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Search term: YDR414C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name ERD1
SGD link S000002822
Alternative ID YDR414C
Description Predicted membrane protein required for the retention of lumenal endoplasmic reticulum proteins; mutants secrete the endogenous ER protein, BiP (Kar2p)
Synonyms YDR414C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1162 ACDHYPE

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Predicted small molecule transporter

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g14040 GI:15223057
Arabidopsis thaliana (Ath) At1g26730 GI:15223330
Arabidopsis thaliana (Ath) At1g35350 GI:15219565
Arabidopsis thaliana (Ath) At1g68740 GI:12324141
Arabidopsis thaliana (Ath) At1g69480 GI:15222329
Arabidopsis thaliana (Ath) At2g03240 GI:15227571
Arabidopsis thaliana (Ath) At2g03250 GI:15227573
Arabidopsis thaliana (Ath) At2g03260 GI:15227575
Arabidopsis thaliana (Ath) At3g23430 GI:15229446
Arabidopsis thaliana (Ath) At3g29060 GI:15228585
Arabidopsis thaliana (Ath) At4g25350 GI:15235030
Arabidopsis thaliana (Ath) At5g35730 GI:9758646
Caenorhabditis elegans (Cel) CE19142
(WBGene00012659)		 GI:17555732 Q9XX10
Drosophila melanogaster (Dme) 7290442 GI:7290442 Q9W4P9
Drosophila melanogaster (Dme) 7293416 GI:7293416
Drosophila melanogaster (Dme) 7295413 GI:7295413
Drosophila melanogaster (Dme) 7298635 GI:7298635
Homo sapiens (Hsa) Hs19923272 GI:16160592
Saccharomyces cerevisiae (Sce) YDR414c
(S000002822)		 GI:6320622 P16151
Saccharomyces cerevisiae (Sce) YIL047c
(S000001309)		 GI:6322142 P40528
Saccharomyces cerevisiae (Sce) YPL110c_1 GI:6325147 Q02979
Schizosaccharomyces pombe (Spo) SPAC1D4.05c GI:19113930 Q10151
Schizosaccharomyces pombe (Spo) SPAC227.01c GI:19113867 Q9UTD8
Schizosaccharomyces pombe (Spo) SPCP1E11.01c GI:19076054
Encephalitozoon cuniculi (Ecu) ECU08g1440 GI:19173469 Q8SUM2
Arabidopsis thaliana (Ath) At1g14040 GI:15223057
Arabidopsis thaliana (Ath) At1g26730 GI:15223330
Arabidopsis thaliana (Ath) At1g35350 GI:15219565
Arabidopsis thaliana (Ath) At1g68740 GI:12324141
Arabidopsis thaliana (Ath) At1g69480 GI:15222329
Arabidopsis thaliana (Ath) At2g03240 GI:15227571
Arabidopsis thaliana (Ath) At2g03250 GI:15227573
Arabidopsis thaliana (Ath) At2g03260 GI:15227575
Arabidopsis thaliana (Ath) At3g23430 GI:15229446
Arabidopsis thaliana (Ath) At3g29060 GI:15228585
Arabidopsis thaliana (Ath) At4g25350 GI:15235030
Arabidopsis thaliana (Ath) At5g35730 GI:9758646
Caenorhabditis elegans (Cel) CE19142
(WBGene00012659)		 GI:17555732 Q9XX10
Drosophila melanogaster (Dme) 7290442 GI:7290442 Q9W4P9
Drosophila melanogaster (Dme) 7293416 GI:7293416
Drosophila melanogaster (Dme) 7295413 GI:7295413
Drosophila melanogaster (Dme) 7298635 GI:7298635
Homo sapiens (Hsa) Hs19923272 GI:16160592
Saccharomyces cerevisiae (Sce) YDR414c
(S000002822)		 GI:6320622 P16151
Saccharomyces cerevisiae (Sce) YIL047c
(S000001309)		 GI:6322142 P40528
Saccharomyces cerevisiae (Sce) YPL110c_1 GI:6325147 Q02979
Schizosaccharomyces pombe (Spo) SPAC1D4.05c GI:19113930 Q10151
Schizosaccharomyces pombe (Spo) SPAC227.01c GI:19113867 Q9UTD8
Schizosaccharomyces pombe (Spo) SPCP1E11.01c GI:19076054
Encephalitozoon cuniculi (Ecu) ECU08g1440 GI:19173469 Q8SUM2


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000329 fungal-type vacuole membrane C
IDA
SpoSPAC227.01c
GO:0005634 nucleus C
IDA
AthAt4g25350
GO:0005737 cytoplasm C
IDA
SpoSPAC227.01c
GO:0005739 mitochondrion C
IDA
SceS000001309
GO:0005783 endoplasmic reticulum C
IDA
SpoSPAC1D4.05c
GO:0005829 cytosol C
IDA
AthAt4g25350
GO:0005886 plasma membrane C
IDA
AthAt1g26730
At1g69480
SceS000001309
GO:0016020 membrane C
IDA
SceS000002822
ISS
SpoSPAC1D4.05c
GO:0016021 integral to membrane C
ISS
AthAt2g03260
At3g23430
At1g35350
At1g69480
At1g26730
At5g35730
At4g25350
At1g68740
At2g03240
At1g14040
At2g03250
At3g29060
SpoSPAC227.01c
GO:0003674 molecular_function F
ND
AthAt1g69480
At1g68740
At5g35730
At4g25350
SceS000002822
S000001309
SpoSPAC1D4.05c
SPAC227.01c
GO:0006486 protein amino acid glycosylation P
IMP
SceS000002822
ISS
SpoSPAC1D4.05c
SPAC227.01c
GO:0006621 protein retention in ER lumen P
IMP
SceS000002822
ISS
SpoSPAC1D4.05c
SPAC227.01c
GO:0006811 ion transport P
RCA
SceS000001309
GO:0006817 phosphate transport P
IMP
AthAt3g23430
At1g68740
GO:0007165 signal transduction P
IMP
SceS000001309
GO:0008150 biological_process P
ND
AthAt1g69480
At5g35730
GO:0009960 endosperm development P
IMP
AthAt4g25350
GO:0010017 red or far-red light signaling
pathway		 P
IMP
AthAt4g25350
GO:0010171 body morphogenesis P
IMP
CelWBGene00012659
GO:0010468 regulation of gene expression P
IMP
AthAt4g25350
GO:0016036 cellular response to phosphate
starvation		 P
IEP
AthAt1g68740
At3g23430
GO:0018991 oviposition P
IMP
CelWBGene00012659
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00012659
GO:0045793 positive regulation of cell size P
IMP
AthAt4g25350
GO:0050801 ion homeostasis P
RCA
SceS000001309
GO:0080050 regulation of seed development P
IMP
AthAt4g25350
GO:0080113 regulation of seed growth P
IMP
AthAt4g25350

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
38821

Species Gene ID NCBI link UniProt link
Schizosaccharomyces pombe (Spo) SPAC1D4.05c GI:19113930 Q10151
Saccharomyces cerevisiae (Sce) ERD1
(S000002822)		 GI:6320622 P16151
Kluyveromyces lactis (Kla) ERD1_KLULA GI:50302313
Eremothecium gossypii (Ego) AGOS_AAR127C GI:45184951
Magnaporthe grisea (Mgr) MGG_11390 GI:145614610
Neurospora crassa (Ncr) NCU03278.1 GI:32420541
Arabidopsis thaliana (Ath) AT5G35730 GI:18421489
Oryza sativa (Osa) Os12g0595000 GI:115489386


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005783 endoplasmic reticulum C
IDA
SpoSPAC1D4.05c
GO:0016020 membrane C
IDA
SceS000002822
ISS
SpoSPAC1D4.05c
GO:0016021 integral to membrane C
ISS
AthAt5g35730
GO:0003674 molecular_function F
ND
AthAt5g35730
SceS000002822
SpoSPAC1D4.05c
GO:0006486 protein amino acid glycosylation P
IMP
SceS000002822
ISS
SpoSPAC1D4.05c
GO:0006621 protein retention in ER lumen P
IMP
SceS000002822
ISS
SpoSPAC1D4.05c
GO:0008150 biological_process P
ND
AthAt5g35730

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_7859

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago314 AAR127C
Arabidopsis thaliana (Ath) ath10243 At2g32295.1
Arabidopsis thaliana (Ath) ath25348 At5g35730.1
Candida glabrata (Cgl) cgl1353 CAGL0F02871g
Cryptococcus neoformans (Cne) cne3866 185.m02452
Debaryomyces hansenii (Dha) dha5626 DEHA0F27731g
Kluyveromyces lactis (Kla) kla88 KLLA0A02057g
Neurospora crassa (Ncr) ncr3176 NCU03278.2
Oryza sativa (Osa) osa58763 6282.m00146
Saccharomyces cerevisiae (Sce) sce1480 YDR414C
(S000002822)
Schizosaccharomyces pombe (Spo) spo2272 SPAC1D4.05c Q10151
Schizosaccharomyces pombe (Spo) spo133 SPAC227.01c Q9UTD8
Yarrowia lipolytica (Yli) yli2059 YALI0C08371g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000329 fungal-type vacuole membrane C
IDA
SpoSPAC227.01c
GO:0005737 cytoplasm C
IDA
SpoSPAC227.01c
GO:0005783 endoplasmic reticulum C
IDA
SpoSPAC1D4.05c
GO:0016020 membrane C
IDA
SceS000002822
ISS
SpoSPAC1D4.05c
GO:0016021 integral to membrane C
ISS
AthAt2g32295
At5g35730
SpoSPAC227.01c
GO:0003674 molecular_function F
ND
AthAt2g32295
At5g35730
SceS000002822
SpoSPAC1D4.05c
SPAC227.01c
GO:0006486 protein amino acid glycosylation P
IMP
SceS000002822
ISS
SpoSPAC1D4.05c
SPAC227.01c
GO:0006621 protein retention in ER lumen P
IMP
SceS000002822
ISS
SpoSPAC1D4.05c
SPAC227.01c
GO:0008150 biological_process P
ND
AthAt2g32295
At5g35730

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC227.01c
(Q9UTD8)		 YDR414C
(S000002822)
SPAC1D4.05c
(Q10151)		 YDR414C
(S000002822)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000329 fungal-type vacuole membrane C
IDA
SpoSPAC227.01c
GO:0005737 cytoplasm C
IDA
SpoSPAC227.01c
GO:0005783 endoplasmic reticulum C
IDA
SpoSPAC1D4.05c
GO:0016020 membrane C
IDA
SceS000002822
ISS
SpoSPAC1D4.05c
GO:0016021 integral to membrane C
ISS
SpoSPAC227.01c
GO:0003674 molecular_function F
ND
SceS000002822
SpoSPAC1D4.05c
SPAC227.01c
GO:0006486 protein amino acid glycosylation P
IMP
SceS000002822
ISS
SpoSPAC1D4.05c
SPAC227.01c
GO:0006621 protein retention in ER lumen P
IMP
SceS000002822
ISS
SpoSPAC1D4.05c
SPAC227.01c

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s.khadayate@ucl.ac.uk