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Search term: YDR416W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name SYF1
SGD link S000002824
Alternative ID YDR416W
Description Member of the NineTeen Complex (NTC) that contains Prp19p and stabilizes U6 snRNA in catalytic forms of the spliceosome containing U2, U5, and U6 snRNAs; null mutant has splicing defect and arrests in G2/M; homologs in human and C. elegans
Synonyms YDR416W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2047 ACDHYP-

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING mRNA splicing factor

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At5g28740 GI:15241911
Caenorhabditis elegans (Cel) CE08909
(WBGene00016837)		 GI:17506161 P91175
Drosophila melanogaster (Dme) 7303287
(FBgn0033859)		 GI:20129961 A1Z9G2
Homo sapiens (Hsa) Hs17482550 GI:17482550
Homo sapiens (Hsa) Hs9910260 GI:9910260
Saccharomyces cerevisiae (Sce) YDR416w
(S000002824)		 GI:6320624 Q04048
Schizosaccharomyces pombe (Spo) SPBC211.02c GI:19113404 Q9P7R9


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000974 Prp19 complex C
IDA
SceS000002824
GO:0005634 nucleus C
IC
DmeFBgn0033859
IDA
SpoSPBC211.02c
GO:0005681 spliceosomal complex C
IDA
SpoSPBC211.02c
GO:0005816 spindle pole body C
IDA
SpoSPBC211.02c
GO:0005829 cytosol C
IDA
SpoSPBC211.02c
GO:0071004 U2-type prespliceosome C
IDA
SceS000002824
GO:0071006 U2-type catalytic step 1 spliceosome C
IDA
SceS000002824
GO:0071007 U2-type catalytic step 2 spliceosome C
IDA
SceS000002824
GO:0071008 U2-type post-mRNA release spliceosomal
complex		 C
IDA
SceS000002824
GO:0071011 precatalytic spliceosome C
IDA
DmeFBgn0033859
GO:0071013 catalytic step 2 spliceosome C
IDA
DmeFBgn0033859
GO:0000384 first spliceosomal transesterification
activity		 F
IC
SceS000002824
GO:0000386 second spliceosomal transesterification
activity		 F
IC
SceS000002824
GO:0003674 molecular_function F
ND
SpoSPBC211.02c
GO:0000003 reproduction P
IMP
CelWBGene00016837
GO:0000349 generation of catalytic spliceosome for first
transesterification step		 P
IDA
SceS000002824
GO:0000381 regulation of alternative nuclear mRNA splicing,
via spliceosome		 P
IMP
DmeFBgn0033859
GO:0000398 nuclear mRNA splicing, via spliceosome P
IC
DmeFBgn0033859
SpoSPBC211.02c
GO:0000910 cytokinesis P
IMP
CelWBGene00016837
GO:0001703 gastrulation with mouth forming
first		 P
IMP
CelWBGene00016837
GO:0002119 nematode larval development P
IMP
CelWBGene00016837
GO:0006911 phagocytosis, engulfment P
IMP
DmeFBgn0033859
GO:0007369 gastrulation P
IMP
CelWBGene00016837
GO:0009790 embryo development P
IMP
CelWBGene00016837
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00016837
GO:0016071 mRNA metabolic process P
RCA
SceS000002824
GO:0040007 growth P
IMP
CelWBGene00016837
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00016837
GO:0051301 cell division P
IMP
CelWBGene00016837

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
68658

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) SYF1
(S000002824)		 GI:6320624 Q04048
Kluyveromyces lactis (Kla) KLLA0A01969g GI:50302305
Eremothecium gossypii (Ego) AGOS_AAR131W GI:45184955


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000974 Prp19 complex C
IDA
SceS000002824
GO:0071004 U2-type prespliceosome C
IDA
SceS000002824
GO:0071006 U2-type catalytic step 1 spliceosome C
IDA
SceS000002824
GO:0071007 U2-type catalytic step 2 spliceosome C
IDA
SceS000002824
GO:0071008 U2-type post-mRNA release spliceosomal
complex		 C
IDA
SceS000002824
GO:0000384 first spliceosomal transesterification
activity		 F
IC
SceS000002824
GO:0000386 second spliceosomal transesterification
activity		 F
IC
SceS000002824
GO:0000349 generation of catalytic spliceosome for first
transesterification step		 P
IDA
SceS000002824
GO:0016071 mRNA metabolic process P
RCA
SceS000002824

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2222

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga9576 ENSANGP00000023353
Ashbya gossypii (Ago) ago318 AAR131W
Arabidopsis thaliana (Ath) ath25153 At5g28740.1
Caenorhabditis elegans (Cel) cel4491 C50F2.3
(CE08909;
WBGene00016837)
Candida glabrata (Cgl) cgl1355 CAGL0F02915g
Cryptococcus neoformans (Cne) cne2984 167.m03286
Dictyostelium discoideum (Ddi) ddi5626 DDB0204337
Debaryomyces hansenii (Dha) dha3662 DEHA0E09537g
Drosophila melanogaster (Dme) dme4944 CG6197-PA
(FBgn0033859)
Danio rerio (Dre) dre31114 ENSDARP00000010070
(LOC555321)		 Q1LY92
Takifugu rubripes (Fru) fru32091 SINFRUP00000152789
Homo sapiens (Hsa) hsa15484 ENSP00000320467
Homo sapiens (Hsa) hsa15483 ENSP00000351137
(XAB2)		 Q9HCS7
Kluyveromyces lactis (Kla) kla84 KLLA0A01969g
Mus musculus (Mmu) mmu25530 ENSMUSP00000019614
(MGI:1914689)		 Q9DCD2
Neurospora crassa (Ncr) ncr7828 NCU08036.2
Oryza sativa (Osa) osa34481 4681.m00170
Oryza sativa (Osa) osa49198 5730.m00083
Oryza sativa (Osa) osa56654 6197.m00157
Plasmodium falciparum (Pfa) pfa5130 PFL1735c
Rattus norvegicus (Rno) rno7937 ENSRNOP00000001309
(RGD:621217)		 Q99PK0
Saccharomyces cerevisiae (Sce) sce1482 YDR416W
(S000002824)
Schizosaccharomyces pombe (Spo) spo3002 SPBC211.02c Q9P7R9
Yarrowia lipolytica (Yli) yli2728 YALI0D00561g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000974 Prp19 complex C
IDA
SceS000002824
GO:0005634 nucleus C
IC
DmeFBgn0033859
IDA
SpoSPBC211.02c
GO:0005681 spliceosomal complex C
IDA
SpoSPBC211.02c
GO:0005816 spindle pole body C
IDA
SpoSPBC211.02c
GO:0005829 cytosol C
IDA
SpoSPBC211.02c
GO:0071004 U2-type prespliceosome C
IDA
SceS000002824
GO:0071006 U2-type catalytic step 1 spliceosome C
IDA
SceS000002824
GO:0071007 U2-type catalytic step 2 spliceosome C
IDA
SceS000002824
GO:0071008 U2-type post-mRNA release spliceosomal
complex		 C
IDA
SceS000002824
GO:0071011 precatalytic spliceosome C
IDA
DmeFBgn0033859
GO:0071013 catalytic step 2 spliceosome C
IDA
DmeFBgn0033859
GO:0000384 first spliceosomal transesterification
activity		 F
IC
SceS000002824
GO:0000386 second spliceosomal transesterification
activity		 F
IC
SceS000002824
GO:0003674 molecular_function F
ND
PfaPFL1735c
SpoSPBC211.02c
GO:0000003 reproduction P
IMP
CelWBGene00016837
GO:0000349 generation of catalytic spliceosome for first
transesterification step		 P
IDA
SceS000002824
GO:0000381 regulation of alternative nuclear mRNA splicing,
via spliceosome		 P
IMP
DmeFBgn0033859
GO:0000398 nuclear mRNA splicing, via spliceosome P
IC
DmeFBgn0033859
SpoSPBC211.02c
GO:0000910 cytokinesis P
IMP
CelWBGene00016837
GO:0001703 gastrulation with mouth forming
first		 P
IMP
CelWBGene00016837
GO:0001824 blastocyst development P
IMP
MmuMGI:1914689
GO:0002119 nematode larval development P
IMP
CelWBGene00016837
GO:0006911 phagocytosis, engulfment P
IMP
DmeFBgn0033859
GO:0007369 gastrulation P
IMP
CelWBGene00016837
GO:0009790 embryo development P
IMP
CelWBGene00016837
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00016837
GO:0016071 mRNA metabolic process P
RCA
SceS000002824
GO:0040007 growth P
IMP
CelWBGene00016837
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00016837
GO:0051301 cell division P
IMP
CelWBGene00016837

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC211.02c
(Q9P7R9)		 YDR416W
(S000002824)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000974 Prp19 complex C
IDA
SceS000002824
GO:0005634 nucleus C
IDA
SpoSPBC211.02c
GO:0005681 spliceosomal complex C
IDA
SpoSPBC211.02c
GO:0005816 spindle pole body C
IDA
SpoSPBC211.02c
GO:0005829 cytosol C
IDA
SpoSPBC211.02c
GO:0071004 U2-type prespliceosome C
IDA
SceS000002824
GO:0071006 U2-type catalytic step 1 spliceosome C
IDA
SceS000002824
GO:0071007 U2-type catalytic step 2 spliceosome C
IDA
SceS000002824
GO:0071008 U2-type post-mRNA release spliceosomal
complex		 C
IDA
SceS000002824
GO:0000384 first spliceosomal transesterification
activity		 F
IC
SceS000002824
GO:0000386 second spliceosomal transesterification
activity		 F
IC
SceS000002824
GO:0003674 molecular_function F
ND
SpoSPBC211.02c
GO:0000349 generation of catalytic spliceosome for first
transesterification step		 P
IDA
SceS000002824
GO:0000398 nuclear mRNA splicing, via spliceosome P
IC
SpoSPBC211.02c
GO:0016071 mRNA metabolic process P
RCA
SceS000002824

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Query species:

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GO info in one table:

s.khadayate@ucl.ac.uk