Bahler Lab

Search term: YDR418W

Gene summary:

Species Saccharomyces cerevisiae (Sce)

Primary name RPL12B

SGD link S000002826

Alternative ID YDR418W

Description Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl12Ap; rpl12a rpl12b double mutant exhibits slow growth and slow translation; has similarity to E. coli L11 and rat L12 ribosomal proteins

Synonyms YDR418W

Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

Search for gene by ID or name:

Query species:

Include wild-cards: Yes No

Search for GO info: Yes No

GO info in one table: Yes No

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)

KOG0886 ACDHYPE

KOGs classification KOGs description

INFORMATION STORAGE AND PROCESSING 40S ribosomal protein S2

GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations

GO:0005634 nucleus C
IDA
Ath At2g37190

GO:0005730 nucleolus C
IDA
Ath At2g37190
Spo SPCC16C4.13c

GO:0005773 vacuole C
IDA
Ath At2g37190

GO:0005811 lipid particle C
IDA
Dme RpL12

GO:0005829 cytosol C
IDA
Spo SPCC16C4.13c
SPCC31H12.04c

GO:0005840 ribosome C
ISS
Ath At2g37190
At3g53430
At5g60670

GO:0009507 chloroplast C
IDA
Ath At2g37190

GO:0016020 membrane C
IDA
Ath At3g53430

GO:0022625 cytosolic large ribosomal subunit C
IDA
Ath At3g53430
At2g37190
At5g60670
ISS
Ath At3g53430
At5g60670
At2g37190
Dme RpL12
Spo SPCC31H12.04c
SPCC16C4.13c
TAS
Sce S000000780
S000002826

GO:0022626 cytosolic ribosome C
IDA
Ath At2g37190

GO:0003674 molecular_function F
ND
Spo SPCC16C4.13c

GO:0003735 structural constituent of ribosome F
ISS
Ath At2g37190
At3g53430
At5g60670
Dme RpL12
TAS
Sce S000000780
S000002826

GO:0008270 zinc ion binding F
IDA
Ath At2g37190

GO:0000003 reproduction P
IMP
Cel WBGene00004424

GO:0000022 mitotic spindle elongation P
IMP
Dme RpL12

GO:0000027 ribosomal large subunit assembly P
IMP
Sce S000000780
S000002826
ISS
Spo SPCC16C4.13c
SPCC31H12.04c

GO:0002119 nematode larval development P
IMP
Cel WBGene00004424

GO:0006412 translation P
ISS
Dme RpL12
Spo SPCC16C4.13c
SPCC31H12.04c
TAS
Sce S000002826
S000000780

GO:0006415 translational termination P
RCA
Sce S000002826

GO:0006417 regulation of translation P
RCA
Sce S000002826
S000000780

GO:0006898 receptor-mediated endocytosis P
IMP
Cel WBGene00004424

GO:0009409 response to cold P
IEP
Ath At2g37190

GO:0009792 embryo development ending in birth or egg
hatching P
IMP
Cel WBGene00004424

GO:0032940 secretion by cell P
IMP
Cel WBGene00004424

GO:0040010 positive regulation of growth rate P
IMP
Cel WBGene00004424

GO:0042254 ribosome biogenesis P
ISS
Ath At3g53430
At5g60670
At2g37190

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern

112233

Species Gene ID NCBI link UniProt link

Pan troglodytes (Ptr) LOC746985 GI:114606936

Mus musculus (Mmu) Gm4957 GI:82878973

Rattus norvegicus (Rno) Rpl12 GI:62653926

Schizosaccharomyces pombe (Spo) rpl12-2
(SPCC31H12.04c) GI:19075397 O75000

Schizosaccharomyces pombe (Spo) rpl12-1 GI:19075423

Saccharomyces cerevisiae (Sce) RPL12B
(S000002826) GI:6320625 P17079

Saccharomyces cerevisiae (Sce) RPL12A
(S000000780) GI:6320781 P17079

Kluyveromyces lactis (Kla) KLLA0A01903g GI:50302299

Eremothecium gossypii (Ego) AGOS_AAR134W GI:45184958

Magnaporthe grisea (Mgr) MGG_06895 GI:145605732

Neurospora crassa (Ncr) NCU01317.1 GI:32412660

Arabidopsis thaliana (Ath) AT5G60670 GI:15239409

Arabidopsis thaliana (Ath) AT2G37190 GI:15228098

Arabidopsis thaliana (Ath) AT3G53430 GI:15231814

Oryza sativa (Osa) Os02g0699600 GI:115448105

Oryza sativa (Osa) Os04g0598200 GI:115460282

Plasmodium falciparum (Pfa) PFE0850c GI:124506259

GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations

GO:0005634 nucleus C
IDA
Ath At2g37190

GO:0005730 nucleolus C
IDA
Ath At2g37190

GO:0005773 vacuole C
IDA
Ath At2g37190

GO:0005829 cytosol C
IDA
Spo SPCC31H12.04c

GO:0005840 ribosome C
ISS
Ath At2g37190
At3g53430
At5g60670

GO:0009507 chloroplast C
IDA
Ath At2g37190

GO:0016020 membrane C
IDA
Ath At3g53430

GO:0022625 cytosolic large ribosomal subunit C
IDA
Ath At3g53430
At2g37190
At5g60670
ISS
Ath At3g53430
At5g60670
At2g37190
Spo SPCC31H12.04c
TAS
Sce S000000780
S000002826

GO:0022626 cytosolic ribosome C
IDA
Ath At2g37190

GO:0003735 structural constituent of ribosome F
ISS
Ath At2g37190
At3g53430
At5g60670
TAS
Sce S000000780
S000002826

GO:0008270 zinc ion binding F
IDA
Ath At2g37190

GO:0000027 ribosomal large subunit assembly P
IMP
Sce S000000780
S000002826
ISS
Spo SPCC31H12.04c

GO:0006412 translation P
ISS
Spo SPCC31H12.04c
TAS
Sce S000002826
S000000780

GO:0006415 translational termination P
RCA
Sce S000002826

GO:0006417 regulation of translation P
RCA
Sce S000002826
S000000780

GO:0009409 response to cold P
IEP
Ath At2g37190

GO:0042254 ribosome biogenesis P
ISS
Ath At3g53430
At5g60670
At2g37190

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern

OG1_858

Species OrthoMCL
sequence Model organism
protein page UniProt link

Anopheles gambiae (Aga) aga12365 ENSANGP00000019214

Ashbya gossypii (Ago) ago321 AAR134W

Arabidopsis thaliana (Ath) ath10801 At2g37190.1

Arabidopsis thaliana (Ath) ath16691 At3g53430.1

Arabidopsis thaliana (Ath) ath28153 At5g60670.1

Caenorhabditis elegans (Cel) cel11520 JC8.3a
(CE17986;
WBGene00004424)

Candida glabrata (Cgl) cgl1356 CAGL0F02937g

Cryptococcus neoformans (Cne) cne5729 179.m00598

Dictyostelium discoideum (Ddi) ddi13273 DDB0229950

Debaryomyces hansenii (Dha) dha3151 DEHA0D19041g

Drosophila melanogaster (Dme) dme6936 CG3195-PA

Drosophila melanogaster (Dme) dme6937 CG3195-PB

Drosophila melanogaster (Dme) dme6935 CG3195-PC

Danio rerio (Dre) dre19451 ENSDARP00000009096
(rpl12) Q5BKW5

Encephalitozoon cuniculi (Ecu) ecu355 19173524

Takifugu rubripes (Fru) fru21861 SINFRUP00000142732

Gallus gallus (Gga) gga8183 ENSGALP00000014298
(RPL12)

Homo sapiens (Hsa) hsa31933 ENSP00000352744

Homo sapiens (Hsa) hsa31931 ENSP00000354739
(RPL12) P30050-1

Homo sapiens (Hsa) hsa31932 ENSP00000355071

Kluyveromyces lactis (Kla) kla81 KLLA0A01903g

Mus musculus (Mmu) mmu14467 ENSMUSP00000048975
(MGI:98002) Q6DI58

Mus musculus (Mmu) mmu4412 ENSMUSP00000071449

Mus musculus (Mmu) mmu1977 ENSMUSP00000074283

Mus musculus (Mmu) mmu17557 ENSMUSP00000080542

Neurospora crassa (Ncr) ncr1276 NCU01317.2

Oryza sativa (Osa) osa25582 3850.m00160

Oryza sativa (Osa) osa45112 5372.m00171

Plasmodium falciparum (Pfa) pfa3619 PFE0850c

Rattus norvegicus (Rno) rno18437 ENSRNOP00000021725

Rattus norvegicus (Rno) rno18436 ENSRNOP00000040848
(RGD:1590883) Q4QQV3

Rattus norvegicus (Rno) rno30768 ENSRNOP00000041462
(RGD:1565106) P23358

Rattus norvegicus (Rno) rno28965 ENSRNOP00000042027

Rattus norvegicus (Rno) rno21309 ENSRNOP00000051432

Saccharomyces cerevisiae (Sce) sce1484 YDR418W
(S000002826)

Saccharomyces cerevisiae (Sce) sce1682 YEL054C
(S000000780)

Schizosaccharomyces pombe (Spo) spo1379 SPCC16C4.13c O75000

Schizosaccharomyces pombe (Spo) spo4859 SPCC31H12.04c O75000

Yarrowia lipolytica (Yli) yli3291 YALI0D13882g

GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations

GO:0005634 nucleus C
IDA
Ath At2g37190
Mmu MGI:98002

GO:0005730 nucleolus C
IDA
Ath At2g37190
Mmu MGI:98002
Spo SPCC16C4.13c

GO:0005737 cytoplasm C
IDA
Mmu MGI:98002

GO:0005773 vacuole C
IDA
Ath At2g37190

GO:0005829 cytosol C
IDA
Spo SPCC16C4.13c
SPCC31H12.04c

GO:0005840 ribosome C
ISS
Ath At2g37190
At3g53430
At5g60670

GO:0009507 chloroplast C
IDA
Ath At2g37190

GO:0016020 membrane C
IDA
Ath At3g53430

GO:0022625 cytosolic large ribosomal subunit C
IDA
Ath At3g53430
At2g37190
At5g60670
ISS
Ath At3g53430
At5g60670
At2g37190
Spo SPCC31H12.04c
SPCC16C4.13c
TAS
Sce S000000780
S000002826

GO:0022626 cytosolic ribosome C
IDA
Ath At2g37190

GO:0003674 molecular_function F
ND
Spo SPCC16C4.13c

GO:0003735 structural constituent of ribosome F
ISS
Ath At2g37190
At3g53430
At5g60670
TAS
Sce S000000780
S000002826

GO:0005515 protein binding F
IPI
Mmu MGI:98002

GO:0008270 zinc ion binding F
IDA
Ath At2g37190

GO:0000003 reproduction P
IMP
Cel WBGene00004424

GO:0000027 ribosomal large subunit assembly P
IMP
Sce S000000780
S000002826
ISS
Spo SPCC16C4.13c
SPCC31H12.04c

GO:0002119 nematode larval development P
IMP
Cel WBGene00004424

GO:0006412 translation P
ISS
Spo SPCC16C4.13c
SPCC31H12.04c
TAS
Sce S000002826
S000000780

GO:0006415 translational termination P
RCA
Sce S000002826

GO:0006417 regulation of translation P
RCA
Sce S000002826
S000000780

GO:0006898 receptor-mediated endocytosis P
IMP
Cel WBGene00004424

GO:0008150 biological_process P
ND
Mmu MGI:98002

GO:0009409 response to cold P
IEP
Ath At2g37190

GO:0009792 embryo development ending in birth or egg
hatching P
IMP
Cel WBGene00004424

GO:0032940 secretion by cell P
IMP
Cel WBGene00004424

GO:0040010 positive regulation of growth rate P
IMP
Cel WBGene00004424

GO:0042254 ribosome biogenesis P
ISS
Ath At3g53430
At5g60670
At2g37190

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Curated yeast ortholog results:

S. pombe
systematic ID S. cerevisiae
systematic ID

SPCC31H12.04c
(O75000) YDR418W
(S000002826)

SPCC16C4.13c
(O75000) YDR418W
(S000002826)

GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations

GO:0005730 nucleolus C
IDA
Spo SPCC16C4.13c

GO:0005829 cytosol C
IDA
Spo SPCC16C4.13c
SPCC31H12.04c

GO:0022625 cytosolic large ribosomal subunit C
ISS
Spo SPCC31H12.04c
SPCC16C4.13c
TAS
Sce S000002826

GO:0003674 molecular_function F
ND
Spo SPCC16C4.13c

GO:0003735 structural constituent of ribosome F
TAS
Sce S000002826

GO:0000027 ribosomal large subunit assembly P
IMP
Sce S000002826
ISS
Spo SPCC16C4.13c
SPCC31H12.04c

GO:0006412 translation P
ISS
Spo SPCC16C4.13c
SPCC31H12.04c
TAS
Sce S000002826

GO:0006415 translational termination P
RCA
Sce S000002826

GO:0006417 regulation of translation P
RCA
Sce S000002826

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YOGY Home

YOGY Help

Search for gene by ID or name:

Query species:

Include wild-cards: Yes No

Search for GO info: Yes No

GO info in one table: Yes No

s.khadayate@ucl.ac.uk

KOG name	Phylogenetic pattern (and link to KOGs with this pattern)
KOG0886	ACDHYPE

KOGs classification	KOGs description
INFORMATION STORAGE AND PROCESSING	40S ribosomal protein S2

Species	KOG link	NCBI link	UniProt link
Arabidopsis thaliana (Ath)	At2g37190	GI:15228098
Arabidopsis thaliana (Ath)	At3g53430	GI:15231814
Arabidopsis thaliana (Ath)	At5g60670	GI:15239409
Caenorhabditis elegans (Cel)	CE17986 (WBGene00004424)	GI:17541134	P61866
Caenorhabditis elegans (Cel)	CE28042	GI:17541136
Drosophila melanogaster (Dme)	7291730 (RpL12)	GI:17864452	Q9W1B9
Homo sapiens (Hsa)	Hs14749869	GI:14749869
Homo sapiens (Hsa)	Hs17438567	GI:17438567
Homo sapiens (Hsa)	Hs18551842	GI:18551842
Homo sapiens (Hsa)	Hs18574558	GI:18574558
Homo sapiens (Hsa)	Hs18599384	GI:18599384
Homo sapiens (Hsa)	Hs20483194	GI:20483194
Homo sapiens (Hsa)	Hs20484271	GI:20484271
Homo sapiens (Hsa)	Hs20535146	GI:20535146
Homo sapiens (Hsa)	Hs20539754	GI:20539754
Homo sapiens (Hsa)	Hs20554345	GI:20554345
Homo sapiens (Hsa)	Hs20554487	GI:20554487
Homo sapiens (Hsa)	Hs20556494	GI:20556494
Homo sapiens (Hsa)	Hs20557305	GI:20557305
Homo sapiens (Hsa)	Hs22050693	GI:22050693
Homo sapiens (Hsa)	Hs22057123	GI:22057123
Homo sapiens (Hsa)	Hs22066150	GI:22066150
Homo sapiens (Hsa)	Hs22066243	GI:22066243
Homo sapiens (Hsa)	Hs4506597 (RPL12)	GI:4506597	P30050
Saccharomyces cerevisiae (Sce)	YDR418w (S000002826)	GI:6320625	P17079
Saccharomyces cerevisiae (Sce)	YEL054c (S000000780)	GI:6320781	P17079
Schizosaccharomyces pombe (Spo)	SPCC16C4.13c	GI:19075397	O75000
Schizosaccharomyces pombe (Spo)	SPCC31H12.04c	GI:19075397	O75000
Encephalitozoon cuniculi (Ecu)	ECU08g2010	GI:19173524	Q8SR84
Arabidopsis thaliana (Ath)	At2g37190	GI:15228098
Arabidopsis thaliana (Ath)	At3g53430	GI:15231814
Arabidopsis thaliana (Ath)	At5g60670	GI:15239409
Caenorhabditis elegans (Cel)	CE17986 (WBGene00004424)	GI:17541134	P61866
Caenorhabditis elegans (Cel)	CE28042	GI:17541136
Drosophila melanogaster (Dme)	7291730 (RpL12)	GI:17864452	Q9W1B9
Homo sapiens (Hsa)	Hs14749869	GI:14749869
Homo sapiens (Hsa)	Hs17438567	GI:17438567
Homo sapiens (Hsa)	Hs18551842	GI:18551842
Homo sapiens (Hsa)	Hs18574558	GI:18574558
Homo sapiens (Hsa)	Hs18599384	GI:18599384
Homo sapiens (Hsa)	Hs20483194	GI:20483194
Homo sapiens (Hsa)	Hs20484271	GI:20484271
Homo sapiens (Hsa)	Hs20535146	GI:20535146
Homo sapiens (Hsa)	Hs20539754	GI:20539754
Homo sapiens (Hsa)	Hs20554345	GI:20554345
Homo sapiens (Hsa)	Hs20554487	GI:20554487
Homo sapiens (Hsa)	Hs20556494	GI:20556494
Homo sapiens (Hsa)	Hs20557305	GI:20557305
Homo sapiens (Hsa)	Hs22050693	GI:22050693
Homo sapiens (Hsa)	Hs22057123	GI:22057123
Homo sapiens (Hsa)	Hs22066150	GI:22066150
Homo sapiens (Hsa)	Hs22066243	GI:22066243
Homo sapiens (Hsa)	Hs4506597 (RPL12)	GI:4506597	P30050
Saccharomyces cerevisiae (Sce)	YDR418w (S000002826)	GI:6320625	P17079
Saccharomyces cerevisiae (Sce)	YEL054c (S000000780)	GI:6320781	P17079
Schizosaccharomyces pombe (Spo)	SPCC16C4.13c	GI:19075397	O75000
Schizosaccharomyces pombe (Spo)	SPCC31H12.04c	GI:19075397	O75000
Encephalitozoon cuniculi (Ecu)	ECU08g2010	GI:19173524	Q8SR84

Species	Gene ID	NCBI link	UniProt link
Pan troglodytes (Ptr)	LOC746985	GI:114606936
Mus musculus (Mmu)	Gm4957	GI:82878973
Rattus norvegicus (Rno)	Rpl12	GI:62653926
Schizosaccharomyces pombe (Spo)	rpl12-2 (SPCC31H12.04c)	GI:19075397	O75000
Schizosaccharomyces pombe (Spo)	rpl12-1	GI:19075423
Saccharomyces cerevisiae (Sce)	RPL12B (S000002826)	GI:6320625	P17079
Saccharomyces cerevisiae (Sce)	RPL12A (S000000780)	GI:6320781	P17079
Kluyveromyces lactis (Kla)	KLLA0A01903g	GI:50302299
Eremothecium gossypii (Ego)	AGOS_AAR134W	GI:45184958
Magnaporthe grisea (Mgr)	MGG_06895	GI:145605732
Neurospora crassa (Ncr)	NCU01317.1	GI:32412660
Arabidopsis thaliana (Ath)	AT5G60670	GI:15239409
Arabidopsis thaliana (Ath)	AT2G37190	GI:15228098
Arabidopsis thaliana (Ath)	AT3G53430	GI:15231814
Oryza sativa (Osa)	Os02g0699600	GI:115448105
Oryza sativa (Osa)	Os04g0598200	GI:115460282
Plasmodium falciparum (Pfa)	PFE0850c	GI:124506259

Species	OrthoMCL sequence	Model organism protein page	UniProt link
Anopheles gambiae (Aga)	aga12365	ENSANGP00000019214
Ashbya gossypii (Ago)	ago321	AAR134W
Arabidopsis thaliana (Ath)	ath10801	At2g37190.1
Arabidopsis thaliana (Ath)	ath16691	At3g53430.1
Arabidopsis thaliana (Ath)	ath28153	At5g60670.1
Caenorhabditis elegans (Cel)	cel11520	JC8.3a (CE17986; WBGene00004424)
Candida glabrata (Cgl)	cgl1356	CAGL0F02937g
Cryptococcus neoformans (Cne)	cne5729	179.m00598
Dictyostelium discoideum (Ddi)	ddi13273	DDB0229950
Debaryomyces hansenii (Dha)	dha3151	DEHA0D19041g
Drosophila melanogaster (Dme)	dme6936	CG3195-PA
Drosophila melanogaster (Dme)	dme6937	CG3195-PB
Drosophila melanogaster (Dme)	dme6935	CG3195-PC
Danio rerio (Dre)	dre19451	ENSDARP00000009096 (rpl12)	Q5BKW5
Encephalitozoon cuniculi (Ecu)	ecu355	19173524
Takifugu rubripes (Fru)	fru21861	SINFRUP00000142732
Gallus gallus (Gga)	gga8183	ENSGALP00000014298 (RPL12)
Homo sapiens (Hsa)	hsa31933	ENSP00000352744
Homo sapiens (Hsa)	hsa31931	ENSP00000354739 (RPL12)	P30050-1
Homo sapiens (Hsa)	hsa31932	ENSP00000355071
Kluyveromyces lactis (Kla)	kla81	KLLA0A01903g
Mus musculus (Mmu)	mmu14467	ENSMUSP00000048975 (MGI:98002)	Q6DI58
Mus musculus (Mmu)	mmu4412	ENSMUSP00000071449
Mus musculus (Mmu)	mmu1977	ENSMUSP00000074283
Mus musculus (Mmu)	mmu17557	ENSMUSP00000080542
Neurospora crassa (Ncr)	ncr1276	NCU01317.2
Oryza sativa (Osa)	osa25582	3850.m00160
Oryza sativa (Osa)	osa45112	5372.m00171
Plasmodium falciparum (Pfa)	pfa3619	PFE0850c
Rattus norvegicus (Rno)	rno18437	ENSRNOP00000021725
Rattus norvegicus (Rno)	rno18436	ENSRNOP00000040848 (RGD:1590883)	Q4QQV3
Rattus norvegicus (Rno)	rno30768	ENSRNOP00000041462 (RGD:1565106)	P23358
Rattus norvegicus (Rno)	rno28965	ENSRNOP00000042027
Rattus norvegicus (Rno)	rno21309	ENSRNOP00000051432
Saccharomyces cerevisiae (Sce)	sce1484	YDR418W (S000002826)
Saccharomyces cerevisiae (Sce)	sce1682	YEL054C (S000000780)
Schizosaccharomyces pombe (Spo)	spo1379	SPCC16C4.13c	O75000
Schizosaccharomyces pombe (Spo)	spo4859	SPCC31H12.04c	O75000
Yarrowia lipolytica (Yli)	yli3291	YALI0D13882g

S. pombe systematic ID	S. cerevisiae systematic ID
SPCC31H12.04c (O75000)	YDR418W (S000002826)
SPCC16C4.13c (O75000)	YDR418W (S000002826)