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Search term: YDR419W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name RAD30
SGD link S000002827
Alternative ID YDR419W
Description DNA polymerase eta, involved in tranlesion synthesis during post-replication repair; catalyzes the synthesis of DNA opposite cyclobutane pyrimidine dimers and other lesions; mutations in human pol eta are responsible for XPV
Synonyms YDR419W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2095 ACDHYP-

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING DNA polymerase iota/DNA damage inducible protein

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At5g44740 GI:2660675
Caenorhabditis elegans (Cel) CE28442 GI:17553546
Drosophila melanogaster (Dme) 7296509 GI:7296509 Q9VNX1
Drosophila melanogaster (Dme) 7298996 GI:7298996
Homo sapiens (Hsa) Hs5729982
(POLH)		 GI:5729982 Q9Y253
Homo sapiens (Hsa) Hs6005848 GI:6005848
Saccharomyces cerevisiae (Sce) YDR419w
(S000002827)		 GI:6320627 Q04049
Schizosaccharomyces pombe (Spo) SPBC16A3.11_1 GI:19113570 O42917


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000790 nuclear chromatin C
IC
SpoSPBC16A3.11
GO:0005634 nucleus C
IDA
HsaPOLH
SpoSPBC16A3.11
GO:0005654 nucleoplasm C
TAS
HsaPOLH
GO:0005657 replication fork C
IPI
SceS000002827
GO:0005737 cytoplasm C
IDA
HsaPOLH
GO:0043596 nuclear replication fork C
IC
SpoSPBC16A3.11
GO:0003887 DNA-directed DNA polymerase activity F
IDA
AthAt5g44740
SceS000002827
ISS
SpoSPBC16A3.11
GO:0005515 protein binding F
IPI
SpoSPBC16A3.11
GO:0008415 acyltransferase activity F
ISS
SpoSPBC16A3.11
GO:0000731 DNA synthesis involved in DNA repair P
IDA
HsaPOLH
GO:0006281 DNA repair P
ISS
AthAt5g44740
SpoSPBC16A3.11
TAS
HsaPOLH
GO:0006282 regulation of DNA repair P
TAS
HsaPOLH
GO:0006473 protein amino acid acetylation P
IC
SpoSPBC16A3.11
GO:0010224 response to UV-B P
IMP
AthAt5g44740
GO:0010225 response to UV-C P
IDA
HsaPOLH
GO:0019985 translesion synthesis P
IMP
SpoSPBC16A3.11
GO:0034087 establishment of mitotic sister chromatid
cohesion		 P
IMP
SpoSPBC16A3.11
GO:0034182 regulation of maintenance of mitotic sister
chromatid cohesion		 P
TAS
SpoSPBC16A3.11
GO:0042276 error-prone translesion synthesis P
IDA
AthAt5g44740
SceS000002827
IMP
SceS000002827
GO:0070987 error-free translesion synthesis P
IDA
SceS000002827

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
44206

Species Gene ID NCBI link UniProt link
Schizosaccharomyces pombe (Spo) eso1
(SPBC16A3.11)		 GI:19113570 O42917
Saccharomyces cerevisiae (Sce) RAD30
(S000002827)		 GI:6320627 Q04049
Kluyveromyces lactis (Kla) KLLA0A01848g GI:50302293
Magnaporthe grisea (Mgr) MGG_02924 GI:39970915
Neurospora crassa (Ncr) NCU01936.1 GI:32417296


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000790 nuclear chromatin C
IC
SpoSPBC16A3.11
GO:0005634 nucleus C
IDA
SpoSPBC16A3.11
GO:0005657 replication fork C
IPI
SceS000002827
GO:0043596 nuclear replication fork C
IC
SpoSPBC16A3.11
GO:0003887 DNA-directed DNA polymerase activity F
IDA
SceS000002827
ISS
SpoSPBC16A3.11
GO:0005515 protein binding F
IPI
SpoSPBC16A3.11
GO:0008415 acyltransferase activity F
ISS
SpoSPBC16A3.11
GO:0006281 DNA repair P
ISS
SpoSPBC16A3.11
GO:0006473 protein amino acid acetylation P
IC
SpoSPBC16A3.11
GO:0019985 translesion synthesis P
IMP
SpoSPBC16A3.11
GO:0034087 establishment of mitotic sister chromatid
cohesion		 P
IMP
SpoSPBC16A3.11
GO:0034182 regulation of maintenance of mitotic sister
chromatid cohesion		 P
TAS
SpoSPBC16A3.11
GO:0042276 error-prone translesion synthesis P
IDA
SceS000002827
IMP
SceS000002827
GO:0070987 error-free translesion synthesis P
IDA
SceS000002827

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_3262

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga3485 ENSANGP00000016819
Ashbya gossypii (Ago) ago323 AAR136W
Arabidopsis thaliana (Ath) ath26309 At5g44740.1
Arabidopsis thaliana (Ath) ath26310 At5g44740.2
Caenorhabditis elegans (Cel) cel9944 F53A3.2
(CE40206;
WBGene00018721)
Candida glabrata (Cgl) cgl1357 CAGL0F02959g
Cryptococcus neoformans (Cne) cne3367 167.m05859
Debaryomyces hansenii (Dha) dha4831 DEHA0F10109g
Drosophila melanogaster (Dme) dme10682 CG7143-PA
(FBgn0037141)
Danio rerio (Dre) dre3805 ENSDARP00000038779
Takifugu rubripes (Fru) fru12596 SINFRUP00000131077
Gallus gallus (Gga) gga14839 ENSGALP00000016779
(POLH)		 Q5ZIW9
Gallus gallus (Gga) gga14841 ENSGALP00000016794
Homo sapiens (Hsa) hsa27201 ENSP00000306591
Kluyveromyces lactis (Kla) kla78 KLLA0A01848g
Mus musculus (Mmu) mmu11784 ENSMUSP00000024749
(MGI:1891457)		 Q9JJN0
Neurospora crassa (Ncr) ncr1885 NCU01936.2
Oryza sativa (Osa) osa12681 2887.m00108
Oryza sativa (Osa) osa31742 4438.m00133
Rattus norvegicus (Rno) rno29682 ENSRNOP00000026049
(RGD:1309893)
Saccharomyces cerevisiae (Sce) sce1485 YDR419W
(S000002827)
Schizosaccharomyces pombe (Spo) spo427 SPBC16A3.11 O42917
Yarrowia lipolytica (Yli) yli1790 YALI0C01573g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000790 nuclear chromatin C
IC
SpoSPBC16A3.11
GO:0005634 nucleus C
IDA
CelWBGene00018721
SpoSPBC16A3.11
TAS
MmuMGI:1891457
GO:0005657 replication fork C
IPI
SceS000002827
GO:0043596 nuclear replication fork C
IC
SpoSPBC16A3.11
GO:0003887 DNA-directed DNA polymerase activity F
IDA
AthAt5g44740
DmeFBgn0037141
MmuMGI:1891457
SceS000002827
IMP
DmeFBgn0037141
ISS
SpoSPBC16A3.11
NAS
DmeFBgn0037141
GO:0005515 protein binding F
IPI
SpoSPBC16A3.11
GO:0008415 acyltransferase activity F
ISS
SpoSPBC16A3.11
GO:0006281 DNA repair P
ISS
AthAt5g44740
SpoSPBC16A3.11
GO:0006290 pyrimidine dimer repair P
IDA
MmuMGI:1891457
GO:0006301 postreplication repair P
IDA
MmuMGI:1891457
GO:0006473 protein amino acid acetylation P
IC
SpoSPBC16A3.11
GO:0010224 response to UV-B P
IMP
AthAt5g44740
GO:0019985 translesion synthesis P
IDA
DmeFBgn0037141
IMP
SpoSPBC16A3.11
ISS
DmeFBgn0037141
NAS
DmeFBgn0037141
GO:0034087 establishment of mitotic sister chromatid
cohesion		 P
IMP
SpoSPBC16A3.11
GO:0034182 regulation of maintenance of mitotic sister
chromatid cohesion		 P
TAS
SpoSPBC16A3.11
GO:0042276 error-prone translesion synthesis P
IDA
AthAt5g44740
SceS000002827
IMP
SceS000002827
GO:0070987 error-free translesion synthesis P
IDA
SceS000002827

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GO info in one table:

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