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Search term: YDR427W


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name RPN9
SGD link S000002835
Alternative ID YDR427W
Description Non-ATPase regulatory subunit of the 26S proteasome, has similarity to putative proteasomal subunits in other species; null mutant is temperature sensitive and exhibits cell cycle and proteasome assembly defects
Synonyms YDR427W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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Query species:

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Search for GO info:  

GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2908 ACDHYPE

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING 26S proteasome regulatory complex, subunit RPN9/PSMD13

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At5g45620 GI:15242452
Caenorhabditis elegans (Cel) CE02329
(WBGene00004465)
GI:17535701 Q22253
Drosophila melanogaster (Dme) 7301037 GI:6434960
Homo sapiens (Hsa) Hs4506223 GI:4506223
Homo sapiens (Hsa) Hs14774537 GI:14774537
Saccharomyces cerevisiae (Sce) YDR427w
(S000002835)
GI:6320635 Q04062
Schizosaccharomyces pombe (Spo) SPAC607.05 GI:19114506 Q9US13
Encephalitozoon cuniculi (Ecu) ECU11g1960 GI:19074996 Q8STZ6


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
TAS
SpoSPAC607.05
GO:0005838 proteasome regulatory particle C
ISS
CelWBGene00004465
GO:0008541 proteasome regulatory particle, lid
subcomplex
C
IDA
SceS000002835
ISS
AthAt5g45620
SpoSPAC607.05
GO:0034515 proteasome storage granule C
IDA
SceS000002835
GO:0003674 molecular_function F
ND
AthAt5g45620
GO:0005198 structural molecule activity F
IMP
SceS000002835
GO:0005515 protein binding F
IPI
CelWBGene00004465
SpoSPAC607.05
GO:0000003 reproduction P
IMP
CelWBGene00004465
GO:0000278 mitotic cell cycle P
IC
SpoSPAC607.05
GO:0002119 nematode larval development P
IMP
CelWBGene00004465
GO:0006508 proteolysis P
RCA
SceS000002835
GO:0006511 ubiquitin-dependent protein catabolic
process
P
IMP
SceS000002835
ISS
SpoSPAC607.05
TAS
AthAt5g45620
GO:0007346 regulation of mitotic cell cycle P
IC
SpoSPAC607.05
GO:0008340 determination of adult lifespan P
IMP
CelWBGene00004465
GO:0009792 embryo development ending in birth or egg
hatching
P
IMP
CelWBGene00004465
GO:0010171 body morphogenesis P
IMP
CelWBGene00004465
GO:0040007 growth P
IMP
CelWBGene00004465
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00004465
GO:0040011 locomotion P
IMP
CelWBGene00004465
GO:0042176 regulation of protein catabolic
process
P
RCA
SceS000002835
GO:0043161 proteasomal ubiquitin-dependent protein catabolic
process
P
NAS
SpoSPAC607.05
GO:0043248 proteasome assembly P
IMP
SceS000002835

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
2110

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) PSMD13 GI:157502193
Pan troglodytes (Ptr) PSMD13 GI:114635315
Canis familiaris (Cfa) PSMD13 GI:73982052
Mus musculus (Mmu) Psmd13
(MGI:1345192)
GI:6755210 B2RT97
Rattus norvegicus (Rno) Psmd13 GI:62641588
Drosophila melanogaster (Dme) Rpn9
(FBgn0028691)
GI:24649397
Anopheles gambiae (Aga) AgaP_AGAP001651 GI:58395698
Caenorhabditis elegans (Cel) rpn-9
(CE02329;
WBGene00004465)
GI:17535701 Q22253
Schizosaccharomyces pombe (Spo) rpn9
(SPAC607.05)
GI:19114506 Q9US13
Saccharomyces cerevisiae (Sce) RPN9
(S000002835)
GI:6320635 Q04062
Kluyveromyces lactis (Kla) KLLA0B00825g GI:50303251
Eremothecium gossypii (Ego) AGOS_ADR191C GI:45188064
Magnaporthe grisea (Mgr) MGG_03524 GI:39942888
Neurospora crassa (Ncr) NCU02374.1 GI:32421413
Arabidopsis thaliana (Ath) AT4G19006 GI:30684612
Arabidopsis thaliana (Ath) AT5G45620 GI:22327608
Oryza sativa (Osa) Os03g0214600 GI:115451543
Oryza sativa (Osa) Os01g0511300 GI:115436936
Plasmodium falciparum (Pfa) PF10_0298 GI:124802745


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
TAS
AthAT4G19006
SpoSPAC607.05
GO:0005838 proteasome regulatory particle C
IDA
DmeFBgn0028691
MmuMGI:1345192
ISS
CelWBGene00004465
DmeFBgn0028691
PfaPF10_0298
TAS
HsaPSMD13
GO:0008541 proteasome regulatory particle, lid
subcomplex
C
IDA
SceS000002835
ISS
AthAt5g45620
AT4G19006
DmeFBgn0028691
SpoSPAC607.05
NAS
DmeFBgn0028691
GO:0034515 proteasome storage granule C
IDA
SceS000002835
GO:0003674 molecular_function F
ND
AthAt5g45620
AT4G19006
GO:0004175 endopeptidase activity F
IDA
DmeFBgn0028691
ISA
MmuMGI:1345192
ISS
PfaPF10_0298
GO:0005198 structural molecule activity F
IMP
SceS000002835
GO:0005515 protein binding F
IPI
CelWBGene00004465
HsaPSMD13
SpoSPAC607.05
GO:0000003 reproduction P
IMP
CelWBGene00004465
GO:0000278 mitotic cell cycle P
IC
SpoSPAC607.05
GO:0002119 nematode larval development P
IMP
CelWBGene00004465
GO:0006508 proteolysis P
IDA
DmeFBgn0028691
ISS
DmeFBgn0028691
RCA
SceS000002835
GO:0006511 ubiquitin-dependent protein catabolic
process
P
IMP
SceS000002835
ISS
AthAT4G19006
PfaPF10_0298
SpoSPAC607.05
TAS
AthAt5g45620
GO:0007096 regulation of exit from mitosis P
IMP
DmeFBgn0028691
GO:0007127 meiosis I P
IMP
MmuMGI:1345192
GO:0007346 regulation of mitotic cell cycle P
IC
SpoSPAC607.05
GO:0008152 metabolic process P
ISA
MmuMGI:1345192
GO:0008340 determination of adult lifespan P
IMP
CelWBGene00004465
GO:0009792 embryo development ending in birth or egg
hatching
P
IMP
CelWBGene00004465
GO:0010171 body morphogenesis P
IMP
CelWBGene00004465
GO:0030163 protein catabolic process P
TAS
AthAT4G19006
GO:0031145 anaphase-promoting complex-dependent proteasomal
ubiquitin-dependent protein catabolic
process
P
EXP
HsaPSMD13
GO:0040007 growth P
IMP
CelWBGene00004465
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00004465
GO:0040011 locomotion P
IMP
CelWBGene00004465
GO:0042176 regulation of protein catabolic
process
P
RCA
SceS000002835
GO:0043161 proteasomal ubiquitin-dependent protein catabolic
process
P
NAS
SpoSPAC607.05
GO:0043248 proteasome assembly P
IMP
SceS000002835
GO:0051436 negative regulation of ubiquitin-protein ligase
activity involved in mitotic cell
cycle
P
EXP
HsaPSMD13
GO:0051437 positive regulation of ubiquitin-protein ligase
activity involved in mitotic cell
cycle
P
EXP
HsaPSMD13

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1289

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Anopheles gambiae (Aga) aga3762 ENSANGP00000008550
Ashbya gossypii (Ago) ago1932 ADR191C
Arabidopsis thaliana (Ath) ath19784 At4g19006.1
Arabidopsis thaliana (Ath) ath26413 At5g45620.1
Arabidopsis thaliana (Ath) ath26414 At5g45620.2
Caenorhabditis elegans (Cel) cel14764 T06D8.8
(CE02329;
WBGene00004465)
Candida glabrata (Cgl) cgl1364 CAGL0F03135g
Cryptococcus neoformans (Cne) cne5017 186.m03937
Dictyostelium discoideum (Ddi) ddi8472 DDB0186342
Debaryomyces hansenii (Dha) dha103 DEHA0A02343g
Drosophila melanogaster (Dme) dme14061 CG10230-PA
(FBgn0028691)
Drosophila melanogaster (Dme) dme14060 CG10230-PB
(FBgn0028691)
Danio rerio (Dre) dre15020 ENSDARP00000009605
Encephalitozoon cuniculi (Ecu) ecu1084 19074996
Takifugu rubripes (Fru) fru21871 SINFRUP00000142752
Gallus gallus (Gga) gga18627 ENSGALP00000006696
(PSMD13)
P84169
Gallus gallus (Gga) gga18626 ENSGALP00000006697
Homo sapiens (Hsa) hsa4869 ENSP00000333811
(PSMD13)
Q9Y6E3
Kluyveromyces lactis (Kla) kla565 KLLA0B00825g
Mus musculus (Mmu) mmu25361 ENSMUSP00000026560
(MGI:1345192)
Q9WVJ2-1
Neurospora crassa (Ncr) ncr2307 NCU02374.2
Oryza sativa (Osa) osa11526 2799.m00137
Oryza sativa (Osa) osa35237 4725.m00146
Oryza sativa (Osa) osa73862 7281.m00090
Oryza sativa (Osa) osa73937 7283.m00109
Plasmodium falciparum (Pfa) pfa516 PF10_0298
Rattus norvegicus (Rno) rno3243 ENSRNOP00000019642
(RGD:1305236)
B0BN93
Saccharomyces cerevisiae (Sce) sce1493 YDR427W
(S000002835)
Schizosaccharomyces pombe (Spo) spo362 SPAC607.05 Q9US13
Yarrowia lipolytica (Yli) yli4161 YALI0E07183g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
TAS
AthAT4G19006
SpoSPAC607.05
GO:0005838 proteasome regulatory particle C
IDA
DmeFBgn0028691
MmuMGI:1345192
ISS
CelWBGene00004465
DmeFBgn0028691
PfaPF10_0298
GO:0008541 proteasome regulatory particle, lid
subcomplex
C
IDA
SceS000002835
ISS
AthAt5g45620
AT4G19006
DmeFBgn0028691
SpoSPAC607.05
NAS
DmeFBgn0028691
GO:0034515 proteasome storage granule C
IDA
SceS000002835
GO:0003674 molecular_function F
ND
AthAt5g45620
AT4G19006
GO:0004175 endopeptidase activity F
IDA
DmeFBgn0028691
ISA
MmuMGI:1345192
ISS
PfaPF10_0298
GO:0005198 structural molecule activity F
IMP
SceS000002835
GO:0005515 protein binding F
IPI
CelWBGene00004465
SpoSPAC607.05
GO:0000003 reproduction P
IMP
CelWBGene00004465
GO:0000278 mitotic cell cycle P
IC
SpoSPAC607.05
GO:0002119 nematode larval development P
IMP
CelWBGene00004465
GO:0006508 proteolysis P
IDA
DmeFBgn0028691
ISS
DmeFBgn0028691
RCA
SceS000002835
GO:0006511 ubiquitin-dependent protein catabolic
process
P
IMP
SceS000002835
ISS
AthAT4G19006
PfaPF10_0298
SpoSPAC607.05
TAS
AthAt5g45620
GO:0007096 regulation of exit from mitosis P
IMP
DmeFBgn0028691
GO:0007127 meiosis I P
IMP
MmuMGI:1345192
GO:0007346 regulation of mitotic cell cycle P
IC
SpoSPAC607.05
GO:0008152 metabolic process P
ISA
MmuMGI:1345192
GO:0008340 determination of adult lifespan P
IMP
CelWBGene00004465
GO:0009792 embryo development ending in birth or egg
hatching
P
IMP
CelWBGene00004465
GO:0010171 body morphogenesis P
IMP
CelWBGene00004465
GO:0030163 protein catabolic process P
TAS
AthAT4G19006
GO:0040007 growth P
IMP
CelWBGene00004465
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00004465
GO:0040011 locomotion P
IMP
CelWBGene00004465
GO:0042176 regulation of protein catabolic
process
P
RCA
SceS000002835
GO:0043161 proteasomal ubiquitin-dependent protein catabolic
process
P
NAS
SpoSPAC607.05
GO:0043248 proteasome assembly P
IMP
SceS000002835

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPAC607.05
(Q9US13)
YDR427W
(S000002835)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
TAS
SpoSPAC607.05
GO:0008541 proteasome regulatory particle, lid
subcomplex
C
IDA
SceS000002835
ISS
SpoSPAC607.05
GO:0034515 proteasome storage granule C
IDA
SceS000002835
GO:0005198 structural molecule activity F
IMP
SceS000002835
GO:0005515 protein binding F
IPI
SpoSPAC607.05
GO:0000278 mitotic cell cycle P
IC
SpoSPAC607.05
GO:0006508 proteolysis P
RCA
SceS000002835
GO:0006511 ubiquitin-dependent protein catabolic
process
P
IMP
SceS000002835
ISS
SpoSPAC607.05
GO:0007346 regulation of mitotic cell cycle P
IC
SpoSPAC607.05
GO:0042176 regulation of protein catabolic
process
P
RCA
SceS000002835
GO:0043161 proteasomal ubiquitin-dependent protein catabolic
process
P
NAS
SpoSPAC607.05
GO:0043248 proteasome assembly P
IMP
SceS000002835

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s.khadayate@ucl.ac.uk