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Search term: YDR430C


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name CYM1
SGD link S000002838
Alternative ID YDR430C
Description Lysine-specific metalloprotease of the mitochondrial intermembrane space, member of the pitrilysin family; degrades proteins and presequence peptides cleaved from imported proteins; required for normal mitochondrial morphology
Synonyms YDR430C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2019 A-DHYP-

KOGs classification KOGs description
POORLY CHARACTERIZEDCELLULAR PROCESSES AND SIGNALING Metalloendoprotease HMP1 (insulinase superfamily)

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g49630 GI:15222789
Arabidopsis thaliana (Ath) At3g19170 GI:15230313
Drosophila melanogaster (Dme) 7302255 GI:7302255
Homo sapiens (Hsa) Hs7657343 GI:7657343
Homo sapiens (Hsa) Hs7662488 GI:7662488
Saccharomyces cerevisiae (Sce) YDR430c
(S000002838)
GI:6320639 P32898
Schizosaccharomyces pombe (Spo) SPBC119.17 GI:19112091 O42908


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
AthAt3g19170
At1g49630
SceS000002838
SpoSPBC119.17
GO:0005758 mitochondrial intermembrane space C
IDA
SceS000002838
ISS
SpoSPBC119.17
GO:0009507 chloroplast C
IDA
AthAt3g19170
At1g49630
GO:0009570 chloroplast stroma C
IDA
AthAt3g19170
GO:0009941 chloroplast envelope C
IDA
AthAt3g19170
GO:0048046 apoplast C
IDA
AthAt3g19170
GO:0004222 metalloendopeptidase activity F
IDA
AthAt3g19170
SceS000002838
IMP
SceS000002838
ISS
AthAt3g19170
At1g49630
GO:0008237 metallopeptidase activity F
ISS
SpoSPBC119.17
GO:0006414 translational elongation P
RCA
SceS000002838
GO:0006508 proteolysis P
IDA
SceS000002838
ISS
AthAt3g19170
At1g49630
SpoSPBC119.17
GO:0006627 protein processing involved in protein targeting
to mitochondrion
P
ISS
SpoSPBC119.17
GO:0046686 response to cadmium ion P
IEP
AthAt3g19170
GO:0051603 proteolysis involved in cellular protein catabolic
process
P
IMP
SceS000002838
ISS
SpoSPBC119.17
GO:0051605 protein maturation by peptide bond
cleavage
P
IDA
AthAt3g19170
At1g49630

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
117778

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) CYM1
(S000002838)
GI:6320639 P32898
Kluyveromyces lactis (Kla) KLLA0B00957g GI:50303263


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
SceS000002838
GO:0005758 mitochondrial intermembrane space C
IDA
SceS000002838
GO:0004222 metalloendopeptidase activity F
IDA
SceS000002838
IMP
SceS000002838
GO:0006414 translational elongation P
RCA
SceS000002838
GO:0006508 proteolysis P
IDA
SceS000002838
GO:0051603 proteolysis involved in cellular protein catabolic
process
P
IMP
SceS000002838

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1541

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Anopheles gambiae (Aga) aga2062 ENSANGP00000011486
Ashbya gossypii (Ago) ago1925 ADR184W
Arabidopsis thaliana (Ath) ath4233 At1g49630.1
Arabidopsis thaliana (Ath) ath4234 At1g49630.2
Arabidopsis thaliana (Ath) ath4235 At1g49630.3
Arabidopsis thaliana (Ath) ath14194 At3g19170.1
Candida glabrata (Cgl) cgl1365 CAGL0F03157g
Dictyostelium discoideum (Ddi) ddi2913 DDB0168367
Debaryomyces hansenii (Dha) dha2411 DEHA0D02585g
Drosophila melanogaster (Dme) dme3343 CG3107-PA
(FBgn0033005)
Drosophila melanogaster (Dme) dme3344 CG3107-PB
(FBgn0033005)
Danio rerio (Dre) dre11774 ENSDARP00000009881
Danio rerio (Dre) dre11772 ENSDARP00000017252
Takifugu rubripes (Fru) fru12454 SINFRUP00000145015
Takifugu rubripes (Fru) fru12455 SINFRUP00000171355
Gallus gallus (Gga) gga9482 ENSGALP00000011368
Gallus gallus (Gga) gga9479 ENSGALP00000011369
Gallus gallus (Gga) gga9481 ENSGALP00000011370
Gallus gallus (Gga) gga9480 ENSGALP00000011372
(PITRM1)
Gallus gallus (Gga) gga9484 ENSGALP00000011373
Homo sapiens (Hsa) hsa3437 ENSP00000224949
(PITRM1)
C9JSL2
Kluyveromyces lactis (Kla) kla571 KLLA0B00957g
Mus musculus (Mmu) mmu6485 ENSMUSP00000021611
(MGI:1916867)
Q8K411-1
Neurospora crassa (Ncr) ncr1234 NCU01272.2
Oryza sativa (Osa) osa29601 4331.m00192
Plasmodium falciparum (Pfa) pfa3836 PF13_0322
Rattus norvegicus (Rno) rno13553 ENSRNOP00000022356
(RGD:1310998)
Saccharomyces cerevisiae (Sce) sce1496 YDR430C
(S000002838)
Schizosaccharomyces pombe (Spo) spo2787 SPBC119.17 O42908
Yarrowia lipolytica (Yli) yli6254 YALI0F21615g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
AthAt3g19170
At1g49630
MmuMGI:1916867
SceS000002838
SpoSPBC119.17
GO:0005758 mitochondrial intermembrane space C
IDA
SceS000002838
ISS
SpoSPBC119.17
GO:0005759 mitochondrial matrix C
ISS
DmeFBgn0033005
GO:0009507 chloroplast C
IDA
AthAt3g19170
At1g49630
GO:0009570 chloroplast stroma C
IDA
AthAt3g19170
GO:0009941 chloroplast envelope C
IDA
AthAt3g19170
GO:0020020 food vacuole C
IDA
PfaPF13_0322
GO:0048046 apoplast C
IDA
AthAt3g19170
GO:0004222 metalloendopeptidase activity F
IDA
AthAt3g19170
SceS000002838
IMP
SceS000002838
ISS
AthAt3g19170
At1g49630
DmeFBgn0033005
TAS
PfaPF13_0322
GO:0008237 metallopeptidase activity F
ISS
SpoSPBC119.17
GO:0006414 translational elongation P
RCA
SceS000002838
GO:0006508 proteolysis P
IDA
SceS000002838
ISS
AthAt3g19170
At1g49630
DmeFBgn0033005
SpoSPBC119.17
GO:0006627 protein processing involved in protein targeting
to mitochondrion
P
ISS
SpoSPBC119.17
GO:0020027 hemoglobin metabolic process P
IDA
PfaPF13_0322
GO:0046686 response to cadmium ion P
IEP
AthAt3g19170
GO:0051603 proteolysis involved in cellular protein catabolic
process
P
IMP
SceS000002838
ISS
SpoSPBC119.17
GO:0051605 protein maturation by peptide bond
cleavage
P
IDA
AthAt3g19170
At1g49630

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPBC119.17
(O42908)
YDR430C
(S000002838)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
SceS000002838
SpoSPBC119.17
GO:0005758 mitochondrial intermembrane space C
IDA
SceS000002838
ISS
SpoSPBC119.17
GO:0004222 metalloendopeptidase activity F
IDA
SceS000002838
IMP
SceS000002838
GO:0008237 metallopeptidase activity F
ISS
SpoSPBC119.17
GO:0006414 translational elongation P
RCA
SceS000002838
GO:0006508 proteolysis P
IDA
SceS000002838
ISS
SpoSPBC119.17
GO:0006627 protein processing involved in protein targeting
to mitochondrion
P
ISS
SpoSPBC119.17
GO:0051603 proteolysis involved in cellular protein catabolic
process
P
IMP
SceS000002838
ISS
SpoSPBC119.17

Back to the top
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GO info in one table:

s.khadayate@ucl.ac.uk