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Search term: YDR435C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name PPM1
SGD link S000002843
Alternative ID YDR435C
Description Carboxyl methyltransferase, methylates the C terminus of the protein phosphatase 2A catalytic subunit (Pph21p or Pph22p), which is important for complex formation with regulatory subunits
Synonyms YDR435C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2918 ACDHYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Carboxymethyl transferase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g02100 GI:15217618
Caenorhabditis elegans (Cel) CE00643
(WBGene00007137)		 GI:17551786 P46554
Drosophila melanogaster (Dme) 7298251
(FBgn0028507)		 GI:19921402
Homo sapiens (Hsa) Hs7662174 GI:7662174
Homo sapiens (Hsa) Hs7705580 GI:7705580
Homo sapiens (Hsa) Hs18585660 GI:18585660
Homo sapiens (Hsa) Hs15082256 GI:15082256
Saccharomyces cerevisiae (Sce) YDR435c
(S000002843)		 GI:6320643 Q04081
Saccharomyces cerevisiae (Sce) YOL141w
(S000005501)		 GI:6324431 Q08282
Schizosaccharomyces pombe (Spo) SPBC19C7.08c GI:19112956 O60157
Schizosaccharomyces pombe (Spo) SPBP8B7.08c GI:19113307 O94257


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt1g02100
SceS000002843
GO:0005634 nucleus C
IDA
SpoSPBC19C7.08c
GO:0005737 cytoplasm C
IDA
SceS000005501
ISS
SpoSPBC19C7.08c
GO:0005739 mitochondrion C
IDA
SceS000005501
SpoSPBP8B7.08c
GO:0005829 cytosol C
IDA
SpoSPBC19C7.08c
GO:0003880 protein C-terminal carboxyl O-methyltransferase
activity		 F
ISS
SpoSPBP8B7.08c
SPBC19C7.08c
GO:0008168 methyltransferase activity F
ISS
AthAt1g02100
GO:0008175 tRNA methyltransferase activity F
IDA
SceS000005501
IMP
SceS000005501
GO:0018423 protein C-terminal leucine carboxyl
O-methyltransferase activity		 F
IMP
SceS000002843
GO:0006481 C-terminal protein amino acid methylation P
IC
SpoSPBC19C7.08c
IMP
SceS000002843
ISS
SpoSPBP8B7.08c
GO:0008150 biological_process P
ND
AthAt1g02100
GO:0030488 tRNA methylation P
IDA
SceS000005501
IMP
SceS000005501
GO:0031591 wybutosine biosynthetic process P
IMP
SceS000005501
ISS
SpoSPBC19C7.08c
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00007137
GO:0043623 cellular protein complex assembly P
IMP
SceS000002843
ISS
SpoSPBP8B7.08c

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
38829

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) PPM1
(S000002843)		 GI:6320643 Q04081
Kluyveromyces lactis (Kla) KLLA0B01089g GI:50303275
Eremothecium gossypii (Ego) AGOS_ADR178W GI:45188051


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
SceS000002843
GO:0018423 protein C-terminal leucine carboxyl
O-methyltransferase activity		 F
IMP
SceS000002843
GO:0006481 C-terminal protein amino acid methylation P
IMP
SceS000002843
GO:0043623 cellular protein complex assembly P
IMP
SceS000002843

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_819

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga10813 ENSANGP00000012366
Ashbya gossypii (Ago) ago1547 ADL194W
Ashbya gossypii (Ago) ago1919 ADR178W
Arabidopsis thaliana (Ath) ath123 At1g02100.1
Arabidopsis thaliana (Ath) ath124 At1g02100.2
Arabidopsis thaliana (Ath) ath125 At1g02100.3
Caenorhabditis elegans (Cel) cel295 B0285.4
(CE00643;
WBGene00007137)
Candida glabrata (Cgl) cgl268 CAGL0B01485g
Candida glabrata (Cgl) cgl1367 CAGL0F03201g
Cryptococcus neoformans (Cne) cne4998 186.m03911
Dictyostelium discoideum (Ddi) ddi8805 DDB0219323
Debaryomyces hansenii (Dha) dha3016 DEHA0D15994g
Debaryomyces hansenii (Dha) dha3017 DEHA0D16016g
Debaryomyces hansenii (Dha) dha3544 DEHA0E06875g
Drosophila melanogaster (Dme) dme2546 CG3793-PA
(FBgn0028507)
Danio rerio (Dre) dre3392 ENSDARP00000010652
(zgc:101094)		 Q66L53
Danio rerio (Dre) dre23590 ENSDARP00000015001
Danio rerio (Dre) dre3393 ENSDARP00000017365
Danio rerio (Dre) dre24618 ENSDARP00000040131
Danio rerio (Dre) dre24619 ENSDARP00000046039
Takifugu rubripes (Fru) fru7758 SINFRUP00000141801
Takifugu rubripes (Fru) fru14877 SINFRUP00000158543
Gallus gallus (Gga) gga6612 ENSGALP00000009589
Gallus gallus (Gga) gga3523 ENSGALP00000027959
(LCMT2)
Homo sapiens (Hsa) hsa10534 ENSP00000307214
(LCMT2)		 O60294
Kluyveromyces lactis (Kla) kla577 KLLA0B01089g
Mus musculus (Mmu) mmu25047 ENSMUSP00000033025
(MGI:1353593)		 A2RTH5
Neurospora crassa (Ncr) ncr5237 NCU05392.2
Neurospora crassa (Ncr) ncr7785 NCU07993.2
Oryza sativa (Osa) osa15170 3028.m00172
Plasmodium falciparum (Pfa) pfa1827 PF14_0376
Rattus norvegicus (Rno) rno19540 ENSRNOP00000015957
Rattus norvegicus (Rno) rno2939 ENSRNOP00000019640
(RGD:735118)		 Q6P4Z6
Saccharomyces cerevisiae (Sce) sce1501 YDR435C
(S000002843)
Saccharomyces cerevisiae (Sce) sce5699 YOL141W
(S000005501)
Schizosaccharomyces pombe (Spo) spo1985 SPBC19C7.08c O60157
Schizosaccharomyces pombe (Spo) spo1482 SPBP8B7.08c O94257
Yarrowia lipolytica (Yli) yli3249 YALI0D12881g
Yarrowia lipolytica (Yli) yli5245 YALI0E33209g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt1g02100
MmuMGI:1353593
SceS000002843
GO:0005634 nucleus C
IDA
SpoSPBC19C7.08c
GO:0005737 cytoplasm C
IDA
SceS000005501
ISS
SpoSPBC19C7.08c
GO:0005739 mitochondrion C
IDA
SceS000005501
SpoSPBP8B7.08c
GO:0005829 cytosol C
IDA
SpoSPBC19C7.08c
GO:0003674 molecular_function F
ND
PfaPF14_0376
GO:0003880 protein C-terminal carboxyl O-methyltransferase
activity		 F
ISO
MmuMGI:1353593
ISS
SpoSPBP8B7.08c
SPBC19C7.08c
GO:0008168 methyltransferase activity F
ISS
AthAt1g02100
GO:0008175 tRNA methyltransferase activity F
IDA
SceS000005501
IMP
SceS000005501
GO:0018423 protein C-terminal leucine carboxyl
O-methyltransferase activity		 F
IMP
SceS000002843
GO:0006481 C-terminal protein amino acid methylation P
IC
SpoSPBC19C7.08c
IMP
SceS000002843
ISO
MmuMGI:1353593
ISS
SpoSPBP8B7.08c
GO:0008150 biological_process P
ND
AthAt1g02100
PfaPF14_0376
GO:0030488 tRNA methylation P
IDA
SceS000005501
IMP
SceS000005501
GO:0031591 wybutosine biosynthetic process P
IMP
SceS000005501
ISS
SpoSPBC19C7.08c
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00007137
GO:0043623 cellular protein complex assembly P
IMP
SceS000002843
ISS
SpoSPBP8B7.08c

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBP8B7.08c
(O94257)		 YDR435C
(S000002843)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
SceS000002843
GO:0005739 mitochondrion C
IDA
SpoSPBP8B7.08c
GO:0003880 protein C-terminal carboxyl O-methyltransferase
activity		 F
ISS
SpoSPBP8B7.08c
GO:0018423 protein C-terminal leucine carboxyl
O-methyltransferase activity		 F
IMP
SceS000002843
GO:0006481 C-terminal protein amino acid methylation P
IMP
SceS000002843
ISS
SpoSPBP8B7.08c
GO:0043623 cellular protein complex assembly P
IMP
SceS000002843
ISS
SpoSPBP8B7.08c

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s.khadayate@ucl.ac.uk