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Search term: YDR443C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name SSN2
SGD link S000002851
Alternative ID YDR443C
Description Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; required for stable association of Srb10p-Srb11p kinase; essential for transcriptional regulation
Synonyms YDR443C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
38831

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) SSN2
(S000002851)		 GI:6320651
Kluyveromyces lactis (Kla) KLLA0B01353g GI:50303299
Eremothecium gossypii (Ego) AGOS_AER323W GI:45190925


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005667 transcription factor complex C
TAS
SceS000002851
GO:0016592 mediator complex C
IDA
SceS000002851
GO:0016251 general RNA polymerase II transcription factor
activity		 F
TAS
SceS000002851
GO:0000122 negative regulation of transcription from RNA
polymerase II promoter		 P
TAS
SceS000002851
GO:0009415 response to water P
RCA
SceS000002851
GO:0070481 nuclear-transcribed mRNA catabolic process,
non-stop decay		 P
IMP
SceS000002851

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_15219

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago2824 AER323W
Candida glabrata (Cgl) cgl3452 CAGL0J10472g
Debaryomyces hansenii (Dha) dha94 DEHA0A02145g
Kluyveromyces lactis (Kla) kla589 KLLA0B01353g
Neurospora crassa (Ncr) ncr3849 NCU03962.2
Saccharomyces cerevisiae (Sce) sce1509 YDR443C
(S000002851)
Schizosaccharomyces pombe (Spo) spo2989 SPAC589.02c Q9HE02
Yarrowia lipolytica (Yli) yli3087 YALI0D09086g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPAC589.02c
GO:0005667 transcription factor complex C
TAS
SceS000002851
GO:0005829 cytosol C
IDA
SpoSPAC589.02c
GO:0016592 mediator complex C
IDA
SceS000002851
SpoSPAC589.02c
GO:0003674 molecular_function F
ND
SpoSPAC589.02c
GO:0016251 general RNA polymerase II transcription factor
activity		 F
TAS
SceS000002851
GO:0000122 negative regulation of transcription from RNA
polymerase II promoter		 P
TAS
SceS000002851
GO:0009415 response to water P
RCA
SceS000002851
GO:0010553 negative regulation of gene-specific transcription
from RNA polymerase II promoter		 P
IEP
SpoSPAC589.02c
GO:0032569 gene-specific transcription from RNA polymerase II
promoter		 P
IC
SpoSPAC589.02c
GO:0070481 nuclear-transcribed mRNA catabolic process,
non-stop decay		 P
IMP
SceS000002851

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC589.02c
(Q9HE02)		 YDR443C
(S000002851)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPAC589.02c
GO:0005667 transcription factor complex C
TAS
SceS000002851
GO:0005829 cytosol C
IDA
SpoSPAC589.02c
GO:0016592 mediator complex C
IDA
SceS000002851
SpoSPAC589.02c
GO:0003674 molecular_function F
ND
SpoSPAC589.02c
GO:0016251 general RNA polymerase II transcription factor
activity		 F
TAS
SceS000002851
GO:0000122 negative regulation of transcription from RNA
polymerase II promoter		 P
TAS
SceS000002851
GO:0009415 response to water P
RCA
SceS000002851
GO:0010553 negative regulation of gene-specific transcription
from RNA polymerase II promoter		 P
IEP
SpoSPAC589.02c
GO:0032569 gene-specific transcription from RNA polymerase II
promoter		 P
IC
SpoSPAC589.02c
GO:0070481 nuclear-transcribed mRNA catabolic process,
non-stop decay		 P
IMP
SceS000002851

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