Search term: YDR460W

Gene summary:

KOG results:

KOG name	Phylogenetic pattern (and link to KOGs with this pattern)
KOG3800	ACDHYPE

KOGs classification	KOGs description
CELLULAR PROCESSES AND SIGNALING	Predicted E3 ubiquitin ligase containing RING finger, subunit of transcription/repair factor TFIIH and CDK-activating kinase assembly factor

Species	KOG link	NCBI link	UniProt link
Arabidopsis thaliana (Ath)	At4g30820_1	GI:2980784
Caenorhabditis elegans (Cel)	CE11002_2	GI:17534305
Drosophila melanogaster (Dme)	7303708 (FBgn0024956)	GI:19921990
Homo sapiens (Hsa)	Hs4505225 (MNAT1)	GI:4505225	P51948
Saccharomyces cerevisiae (Sce)	YDR460w (S000002868)	GI:6320668	Q03290
Schizosaccharomyces pombe (Spo)	SPBC776.18c	GI:19113126	O94684
Encephalitozoon cuniculi (Ecu)	ECU11g0220	GI:19074822	Q8SQZ2

GO terms for KOG results:

GO ID	GO term	GO aspect	Evidence codes and associations
GO:0000112	nucleotide-excision repair factor 3 complex	C	ISS Spo SPBC776.18c
GO:0005634	nucleus	C	IDA Hsa MNAT1 Spo SPBC776.18c
GO:0005654	nucleoplasm	C	EXP Hsa MNAT1
GO:0005675	holo TFIIH complex	C	IDA Hsa MNAT1 Sce S000002868 ISS Dme FBgn0024956 TAS Spo SPBC776.18c
GO:0005737	cytoplasm	C	IDA Hsa MNAT1
GO:0005829	cytosol	C	IDA Spo SPBC776.18c
GO:0043231	intracellular membrane-bounded organelle	C	IDA Hsa MNAT1
GO:0070985	TFIIK complex	C	IDA Sce S000002868
GO:0003674	molecular_function	F	ND Ath At4g30820
GO:0004672	protein kinase activity	F	IDA Hsa MNAT1
GO:0004842	ubiquitin-protein ligase activity	F	ISS Spo SPBC776.18c
GO:0005515	protein binding	F	IPI Hsa MNAT1 Spo SPBC776.18c
GO:0008094	DNA-dependent ATPase activity	F	IDA Hsa MNAT1
GO:0008270	zinc ion binding	F	ISS Spo SPBC776.18c
GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity	F	IDA Hsa MNAT1
GO:0016251	general RNA polymerase II transcription factor activity	F	IDA Sce S000002868 ISS Dme FBgn0024956
GO:0047485	protein N-terminus binding	F	IPI Hsa MNAT1
GO:0000079	regulation of cyclin-dependent protein kinase activity	P	IGI Spo SPBC776.18c TAS Hsa MNAT1
GO:0000718	nucleotide-excision repair, DNA damage removal	P	EXP Hsa MNAT1
GO:0006281	DNA repair	P	TAS Hsa MNAT1
GO:0006289	nucleotide-excision repair	P	IMP Sce S000002868 ISS Spo SPBC776.18c
GO:0006357	regulation of transcription from RNA polymerase II promoter	P	IDA Hsa MNAT1
GO:0006366	transcription from RNA polymerase II promoter	P	IDA Hsa MNAT1
GO:0006367	transcription initiation from RNA polymerase II promoter	P	EXP Hsa MNAT1 IC Spo SPBC776.18c ISS Dme FBgn0024956
GO:0006368	RNA elongation from RNA polymerase II promoter	P	EXP Hsa MNAT1
GO:0006461	protein complex assembly	P	TAS Hsa MNAT1
GO:0006914	autophagy	P	RCA Sce S000002868
GO:0008283	cell proliferation	P	TAS Hsa MNAT1
GO:0016567	protein ubiquitination	P	ISS Spo SPBC776.18c
GO:0032568	general transcription from RNA polymerase II promoter	P	IDA Sce S000002868
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	P	IDA Hsa MNAT1 IMP Hsa MNAT1
GO:0070816	phosphorylation of RNA polymerase II C-terminal domain	P	IDA Sce S000002868

HomoloGene results:

HomoloGene cluster	Phylogenetic pattern
1821

Species	Gene ID	NCBI link	UniProt link
Homo sapiens (Hsa)	MNAT1	GI:4505225	P51948
Pan troglodytes (Ptr)	MNAT1	GI:114653355
Canis familiaris (Cfa)	MNAT1	GI:57090199
Mus musculus (Mmu)	Mnat1 (MGI:106207)	GI:89363038	A4FUR7
Rattus norvegicus (Rno)	Mnat1 (RGD:628874)	GI:23618897
Gallus gallus (Gga)	MNAT1	GI:118092137
Drosophila melanogaster (Dme)	Mat1 (FBgn0024956)	GI:19921990
Anopheles gambiae (Aga)	AgaP_AGAP008991	GI:118791406
Caenorhabditis elegans (Cel)	mnat-1 (CE31957; WBGene00018769)	GI:32564565
Schizosaccharomyces pombe (Spo)	mcr1	GI:19113126
Saccharomyces cerevisiae (Sce)	TFB3 (S000002868)	GI:6320668	Q03290
Kluyveromyces lactis (Kla)	KLLA0C14872g	GI:50305811
Eremothecium gossypii (Ego)	AGOS_ABR202C	GI:45185434
Magnaporthe grisea (Mgr)	MGG_03605	GI:39943050
Neurospora crassa (Ncr)	NCU02587.1	GI:32422685

GO terms for Homologene results:

GO ID	GO term	GO aspect	Evidence codes and associations
GO:0005634	nucleus	C	IDA Hsa MNAT1
GO:0005654	nucleoplasm	C	EXP Hsa MNAT1
GO:0005675	holo TFIIH complex	C	IDA Hsa MNAT1 Sce S000002868 ISS Dme FBgn0024956
GO:0005737	cytoplasm	C	IDA Hsa MNAT1
GO:0043231	intracellular membrane-bounded organelle	C	IDA Hsa MNAT1
GO:0070985	TFIIK complex	C	IDA Sce S000002868
GO:0004672	protein kinase activity	F	IDA Hsa MNAT1
GO:0005515	protein binding	F	IPI Hsa MNAT1 Mmu MGI:106207
GO:0008094	DNA-dependent ATPase activity	F	IDA Hsa MNAT1
GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity	F	IDA Hsa MNAT1
GO:0016251	general RNA polymerase II transcription factor activity	F	IDA Sce S000002868 ISS Dme FBgn0024956
GO:0047485	protein N-terminus binding	F	IPI Hsa MNAT1
GO:0000003	reproduction	P	IMP Cel WBGene00018769
GO:0000079	regulation of cyclin-dependent protein kinase activity	P	TAS Hsa MNAT1
GO:0000082	G1/S transition of mitotic cell cycle	P	ISO Mmu MGI:106207
GO:0000718	nucleotide-excision repair, DNA damage removal	P	EXP Hsa MNAT1
GO:0006281	DNA repair	P	TAS Hsa MNAT1
GO:0006289	nucleotide-excision repair	P	IMP Sce S000002868
GO:0006355	regulation of transcription, DNA-dependent	P	IMP Mmu MGI:106207
GO:0006357	regulation of transcription from RNA polymerase II promoter	P	IDA Hsa MNAT1
GO:0006366	transcription from RNA polymerase II promoter	P	IDA Hsa MNAT1
GO:0006367	transcription initiation from RNA polymerase II promoter	P	EXP Hsa MNAT1 ISS Dme FBgn0024956
GO:0006368	RNA elongation from RNA polymerase II promoter	P	EXP Hsa MNAT1
GO:0006461	protein complex assembly	P	TAS Hsa MNAT1
GO:0006914	autophagy	P	RCA Sce S000002868
GO:0006915	apoptosis	P	IMP Mmu MGI:106207
GO:0007512	adult heart development	P	IMP Mmu MGI:106207
GO:0008283	cell proliferation	P	TAS Hsa MNAT1
GO:0009792	embryo development ending in birth or egg hatching	P	IMP Cel WBGene00018769
GO:0021591	ventricular system development	P	IMP Mmu MGI:106207
GO:0032568	general transcription from RNA polymerase II promoter	P	IDA Sce S000002868
GO:0043066	negative regulation of apoptosis	P	ISO Mmu MGI:106207
GO:0044236	multicellular organismal metabolic process	P	IMP Mmu MGI:106207
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	P	IDA Hsa MNAT1 IMP Hsa MNAT1
GO:0048661	positive regulation of smooth muscle cell proliferation	P	ISO Mmu MGI:106207
GO:0050790	regulation of catalytic activity	P	IMP Mmu MGI:106207
GO:0051592	response to calcium ion	P	IMP Mmu MGI:106207
GO:0070816	phosphorylation of RNA polymerase II C-terminal domain	P	IDA Sce S000002868

OrthoMCL results:

OrthoMCL cluster	Phylogenetic pattern
OG1_2180

Species	OrthoMCL sequence	Model organism protein page	UniProt link
Anopheles gambiae (Aga)	aga11081	ENSANGP00000017209
Ashbya gossypii (Ago)	ago796	ABR202C
Arabidopsis thaliana (Ath)	ath21140	At4g30820.1
Arabidopsis thaliana (Ath)	ath21141	At4g30820.2
Caenorhabditis elegans (Cel)	cel10081	F53G2.7 (CE31957; WBGene00018769)
Candida glabrata (Cgl)	cgl3795	CAGL0K06369g
Cryptococcus neoformans (Cne)	cne1335	180.m00282
Dictyostelium discoideum (Ddi)	ddi8111	DDB0188247
Debaryomyces hansenii (Dha)	dha3952	DEHA0E16005g
Drosophila melanogaster (Dme)	dme4373	CG7614-PA (FBgn0024956)
Danio rerio (Dre)	dre4406	ENSDARP00000027502 (zgc:101599)	Q5XJT0
Encephalitozoon cuniculi (Ecu)	ecu910	19074822
Takifugu rubripes (Fru)	fru20349	SINFRUP00000151680
Takifugu rubripes (Fru)	fru20350	SINFRUP00000172943
Gallus gallus (Gga)	gga19952	ENSGALP00000019408 (MNAT1)
Gallus gallus (Gga)	gga19953	ENSGALP00000019409
Homo sapiens (Hsa)	hsa9629	ENSP00000261245 (MNAT1)	P51948
Kluyveromyces lactis (Kla)	kla1865	KLLA0C14872g
Mus musculus (Mmu)	mmu5843	ENSMUSP00000021523 (MGI:106207)	P51949
Neurospora crassa (Ncr)	ncr2505	NCU02587.2
Oryza sativa (Osa)	osa14544	3016.m00063
Oryza sativa (Osa)	osa71204	7159.m00191
Plasmodium falciparum (Pfa)	pfa3572	PFE0610c
Rattus norvegicus (Rno)	rno25262	ENSRNOP00000010163 (RGD:628874)	Q8CIR5
Saccharomyces cerevisiae (Sce)	sce1526	YDR460W (S000002868)
Schizosaccharomyces pombe (Spo)	spo2118	SPBC776.18c	O94684
Yarrowia lipolytica (Yli)	yli3934	YALI0E01826g

GO terms for OrthoMCL results:

GO ID	GO term	GO aspect	Evidence codes and associations
GO:0000112	nucleotide-excision repair factor 3 complex	C	ISS Spo SPBC776.18c
GO:0005634	nucleus	C	IDA Spo SPBC776.18c
GO:0005675	holo TFIIH complex	C	IDA Sce S000002868 ISS Dme FBgn0024956 TAS Spo SPBC776.18c
GO:0005829	cytosol	C	IDA Spo SPBC776.18c
GO:0070985	TFIIK complex	C	IDA Sce S000002868
GO:0003674	molecular_function	F	ND Ath At4g30820
GO:0004842	ubiquitin-protein ligase activity	F	ISS Spo SPBC776.18c
GO:0005515	protein binding	F	IPI Mmu MGI:106207 Spo SPBC776.18c
GO:0008270	zinc ion binding	F	ISS Spo SPBC776.18c
GO:0016251	general RNA polymerase II transcription factor activity	F	IDA Sce S000002868 ISS Dme FBgn0024956
GO:0000003	reproduction	P	IMP Cel WBGene00018769
GO:0000079	regulation of cyclin-dependent protein kinase activity	P	IGI Spo SPBC776.18c
GO:0000082	G1/S transition of mitotic cell cycle	P	ISO Mmu MGI:106207
GO:0006289	nucleotide-excision repair	P	IMP Sce S000002868 ISS Spo SPBC776.18c
GO:0006355	regulation of transcription, DNA-dependent	P	IMP Mmu MGI:106207
GO:0006367	transcription initiation from RNA polymerase II promoter	P	IC Spo SPBC776.18c ISS Dme FBgn0024956
GO:0006914	autophagy	P	RCA Sce S000002868
GO:0006915	apoptosis	P	IMP Mmu MGI:106207
GO:0007512	adult heart development	P	IMP Mmu MGI:106207
GO:0009792	embryo development ending in birth or egg hatching	P	IMP Cel WBGene00018769
GO:0016567	protein ubiquitination	P	ISS Spo SPBC776.18c
GO:0021591	ventricular system development	P	IMP Mmu MGI:106207
GO:0032568	general transcription from RNA polymerase II promoter	P	IDA Sce S000002868
GO:0043066	negative regulation of apoptosis	P	ISO Mmu MGI:106207
GO:0044236	multicellular organismal metabolic process	P	IMP Mmu MGI:106207
GO:0048661	positive regulation of smooth muscle cell proliferation	P	ISO Mmu MGI:106207
GO:0050790	regulation of catalytic activity	P	IMP Mmu MGI:106207
GO:0051592	response to calcium ion	P	IMP Mmu MGI:106207
GO:0070816	phosphorylation of RNA polymerase II C-terminal domain	P	IDA Sce S000002868

Curated yeast ortholog results:

S. pombe systematic ID	S. cerevisiae systematic ID
SPBC776.18c (O94684)	YDR460W (S000002868)

GO terms for curated homolog results:

GO ID	GO term	GO aspect	Evidence codes and associations
GO:0000112	nucleotide-excision repair factor 3 complex	C	ISS Spo SPBC776.18c
GO:0005634	nucleus	C	IDA Spo SPBC776.18c
GO:0005675	holo TFIIH complex	C	IDA Sce S000002868 TAS Spo SPBC776.18c
GO:0005829	cytosol	C	IDA Spo SPBC776.18c
GO:0070985	TFIIK complex	C	IDA Sce S000002868
GO:0004842	ubiquitin-protein ligase activity	F	ISS Spo SPBC776.18c
GO:0005515	protein binding	F	IPI Spo SPBC776.18c
GO:0008270	zinc ion binding	F	ISS Spo SPBC776.18c
GO:0016251	general RNA polymerase II transcription factor activity	F	IDA Sce S000002868
GO:0000079	regulation of cyclin-dependent protein kinase activity	P	IGI Spo SPBC776.18c
GO:0006289	nucleotide-excision repair	P	IMP Sce S000002868 ISS Spo SPBC776.18c
GO:0006367	transcription initiation from RNA polymerase II promoter	P	IC Spo SPBC776.18c
GO:0006914	autophagy	P	RCA Sce S000002868
GO:0016567	protein ubiquitination	P	ISS Spo SPBC776.18c
GO:0032568	general transcription from RNA polymerase II promoter	P	IDA Sce S000002868
GO:0070816	phosphorylation of RNA polymerase II C-terminal domain	P	IDA Sce S000002868