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Search term: YDR469W


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name SDC1
SGD link S000002877
Alternative ID YDR469W
Description Subunit of the COMPASS (Set1C) complex, which methylates lysine 4 of histone H3 and is required in chromatin silencing at telomeres; contains a Dpy-30 domain that mediates interaction with Bre2p; similar to C. elegans and human DPY-30
Synonyms YDR469W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG4109 -CDHYP-

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING Histone H3 (Lys4) methyltransferase complex, subunit CPS25/DPY-30

Species KOG link NCBI link UniProt link
Caenorhabditis elegans (Cel) CE15445
(WBGene00001088)
GI:17559182 Q10661
Drosophila melanogaster (Dme) 7292426 GI:7292426
Drosophila melanogaster (Dme) 7297750 GI:7297750
Homo sapiens (Hsa) Hs14211889
(DPY30)
GI:14211889 Q9C005
Saccharomyces cerevisiae (Sce) YDR469w
(S000002877)
GI:6320677 Q03323
Schizosaccharomyces pombe (Spo) SPCC18.11c GI:19075890 O74861


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000790 nuclear chromatin C
IC
SpoSPCC18.11c
GO:0005634 nucleus C
IDA
CelWBGene00001088
HsaDPY30
SpoSPCC18.11c
GO:0005802 trans-Golgi network C
IDA
HsaDPY30
GO:0005829 cytosol C
IDA
SpoSPCC18.11c
GO:0035097 histone methyltransferase complex C
IDA
HsaDPY30
GO:0048188 Set1C/COMPASS complex C
IDA
SpoSPCC18.11c
IPI
SceS000002877
GO:0048189 Lid2 complex C
IDA
SpoSPCC18.11c
GO:0003674 molecular_function F
ND
SpoSPCC18.11c
GO:0005515 protein binding F
IPI
HsaDPY30
GO:0042800 histone methyltransferase activity (H3-K4
specific)
F
IDA
SceS000002877
IMP
SceS000002877
GO:0042802 identical protein binding F
IPI
HsaDPY30
GO:0042803 protein homodimerization activity F
IPI
HsaDPY30
GO:0000003 reproduction P
IMP
CelWBGene00001088
GO:0002119 nematode larval development P
IMP
CelWBGene00001088
GO:0006338 chromatin remodeling P
IC
SpoSPCC18.11c
GO:0006348 chromatin silencing at telomere P
IMP
SceS000002877
GO:0006730 one-carbon metabolic process P
RCA
SceS000002877
GO:0009792 embryo development ending in birth or egg
hatching
P
IMP
CelWBGene00001088
GO:0010171 body morphogenesis P
IMP
CelWBGene00001088
GO:0016197 endosome transport P
IMP
HsaDPY30
GO:0016571 histone methylation P
IMP
SpoSPCC18.11c
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00001088
GO:0040011 locomotion P
IMP
CelWBGene00001088
GO:0040014 regulation of multicellular organism
growth
P
IMP
CelWBGene00001088
GO:0040017 positive regulation of locomotion P
IMP
CelWBGene00001088
GO:0042464 dosage compensation, by hypoactivation of X
chromosome
P
IMP
CelWBGene00001088
GO:0045138 tail tip morphogenesis P
IMP
CelWBGene00001088
GO:0051568 histone H3-K4 methylation P
IDA
HsaDPY30
SceS000002877
IMP
SceS000002877

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_4531

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Ashbya gossypii (Ago) ago3566 AFR374C
Caenorhabditis elegans (Cel) cel22306 ZK863.6
(CE15445;
WBGene00001088)
Candida glabrata (Cgl) cgl3802 CAGL0K06523g
Debaryomyces hansenii (Dha) dha5938 DEHA0G05390g
Drosophila melanogaster (Dme) dme7880 CG11591-PA
(FBgn0035491)
Drosophila melanogaster (Dme) dme1891 CG6444-PA
(FBgn0032293)
Danio rerio (Dre) dre609 ENSDARP00000017331
(zgc:92638)
Q6DH57
Takifugu rubripes (Fru) fru13553 SINFRUP00000129453
Gallus gallus (Gga) gga14918 ENSGALP00000017260
(DPY30)
Homo sapiens (Hsa) hsa17675 ENSP00000295066
(DPY30)
Q9C005
Homo sapiens (Hsa) hsa17676 ENSP00000345837
(DPY30)
Q9C005
Kluyveromyces lactis (Kla) kla3102 KLLA0E03421g
Mus musculus (Mmu) mmu12100 ENSMUSP00000024868
Neurospora crassa (Ncr) ncr2942 NCU03037.2
Rattus norvegicus (Rno) rno24742 ENSRNOP00000035649
(RGD:708575)
Q8K3E7
Saccharomyces cerevisiae (Sce) sce1536 YDR469W
(S000002877)
Schizosaccharomyces pombe (Spo) spo689 SPCC18.11c O74861
Yarrowia lipolytica (Yli) yli979 YALI0B05830g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000790 nuclear chromatin C
IC
SpoSPCC18.11c
GO:0005634 nucleus C
IDA
CelWBGene00001088
SpoSPCC18.11c
GO:0005829 cytosol C
IDA
SpoSPCC18.11c
GO:0048188 Set1C/COMPASS complex C
IDA
SpoSPCC18.11c
IPI
SceS000002877
GO:0048189 Lid2 complex C
IDA
SpoSPCC18.11c
GO:0003674 molecular_function F
ND
SpoSPCC18.11c
GO:0042800 histone methyltransferase activity (H3-K4
specific)
F
IDA
SceS000002877
IMP
SceS000002877
GO:0000003 reproduction P
IMP
CelWBGene00001088
GO:0002119 nematode larval development P
IMP
CelWBGene00001088
GO:0006338 chromatin remodeling P
IC
SpoSPCC18.11c
GO:0006348 chromatin silencing at telomere P
IMP
SceS000002877
GO:0006730 one-carbon metabolic process P
RCA
SceS000002877
GO:0009792 embryo development ending in birth or egg
hatching
P
IMP
CelWBGene00001088
GO:0010171 body morphogenesis P
IMP
CelWBGene00001088
GO:0016571 histone methylation P
IMP
SpoSPCC18.11c
GO:0030317 sperm motility P
IMP
DmeFBgn0035491
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00001088
GO:0040011 locomotion P
IMP
CelWBGene00001088
GO:0040014 regulation of multicellular organism
growth
P
IMP
CelWBGene00001088
GO:0040017 positive regulation of locomotion P
IMP
CelWBGene00001088
GO:0042464 dosage compensation, by hypoactivation of X
chromosome
P
IMP
CelWBGene00001088
GO:0045138 tail tip morphogenesis P
IMP
CelWBGene00001088
GO:0051568 histone H3-K4 methylation P
IDA
SceS000002877
IMP
SceS000002877

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPCC18.11c
(O74861)
YDR469W
(S000002877)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000790 nuclear chromatin C
IC
SpoSPCC18.11c
GO:0005634 nucleus C
IDA
SpoSPCC18.11c
GO:0005829 cytosol C
IDA
SpoSPCC18.11c
GO:0048188 Set1C/COMPASS complex C
IDA
SpoSPCC18.11c
IPI
SceS000002877
GO:0048189 Lid2 complex C
IDA
SpoSPCC18.11c
GO:0003674 molecular_function F
ND
SpoSPCC18.11c
GO:0042800 histone methyltransferase activity (H3-K4
specific)
F
IDA
SceS000002877
IMP
SceS000002877
GO:0006338 chromatin remodeling P
IC
SpoSPCC18.11c
GO:0006348 chromatin silencing at telomere P
IMP
SceS000002877
GO:0006730 one-carbon metabolic process P
RCA
SceS000002877
GO:0016571 histone methylation P
IMP
SpoSPCC18.11c
GO:0051568 histone H3-K4 methylation P
IDA
SceS000002877
IMP
SceS000002877

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Search for gene by ID or name:

Query species:

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Search for GO info:  

GO info in one table:

s.khadayate@ucl.ac.uk