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Search term: YDR517W


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name GRH1
SGD link S000002925
Alternative ID YDR517W
Description Acetylated, cis-golgi localized protein involved in ER to Golgi transport; homolog of human GRASP65; forms a complex with the coiled-coil protein Bug1p; mutants are compromised for the fusion of ER-derived vesicles with Golgi membranes
Synonyms YDR517W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG3834 -CDHYPE

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Golgi reassembly stacking protein GRASP65, contains PDZ domain

Species KOG link NCBI link UniProt link
Caenorhabditis elegans (Cel) CE25278
(WBGene00021536)
GI:17543358 Q9N3Y1
Drosophila melanogaster (Dme) 7293723 GI:7293723 Q9VW57
Homo sapiens (Hsa) Hs13994253
(GORASP1)
GI:13994253 Q9BQQ3
Homo sapiens (Hsa) Hs20127539 GI:20127539
Saccharomyces cerevisiae (Sce) YDR517w
(S000002925)
GI:6320725 Q04410
Schizosaccharomyces pombe (Spo) SPAC1D4.02c GI:19113927 Q10149
Encephalitozoon cuniculi (Ecu) ECU01g0530 GI:19075062


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPAC1D4.02c
GO:0005737 cytoplasm C
IDA
SceS000002925
ISS
SpoSPAC1D4.02c
GO:0005794 Golgi apparatus C
ISS
SpoSPAC1D4.02c
GO:0005801 cis-Golgi network C
IDA
SceS000002925
IMP
SceS000002925
GO:0005829 cytosol C
EXP
HsaGORASP1
IDA
SpoSPAC1D4.02c
GO:0030127 COPII vesicle coat C
IDA
SceS000002925
GO:0032153 cell division site C
IDA
SpoSPAC1D4.02c
GO:0051286 cell tip C
IDA
SpoSPAC1D4.02c
GO:0003674 molecular_function F
ND
SceS000002925
SpoSPAC1D4.02c
GO:0006888 ER to Golgi vesicle-mediated transport P
IGI
SceS000002925
IMP
SceS000002925
ISS
SpoSPAC1D4.02c
GO:0007030 Golgi organization P
ISS
SceS000002925
SpoSPAC1D4.02c
GO:0007165 signal transduction P
NAS
SpoSPAC1D4.02c
GO:0009306 protein secretion P
IMP
SceS000002925

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
117781

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) GRH1
(S000002925)
GI:6320725 Q04410
Kluyveromyces lactis (Kla) KLLA0C01133g GI:50304579
Eremothecium gossypii (Ego) AGOS_AFR717W GI:45199236


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000002925
GO:0005801 cis-Golgi network C
IDA
SceS000002925
IMP
SceS000002925
GO:0030127 COPII vesicle coat C
IDA
SceS000002925
GO:0003674 molecular_function F
ND
SceS000002925
GO:0006888 ER to Golgi vesicle-mediated transport P
IGI
SceS000002925
IMP
SceS000002925
GO:0007030 Golgi organization P
ISS
SceS000002925
GO:0009306 protein secretion P
IMP
SceS000002925

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1834

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Anopheles gambiae (Aga) aga2806 ENSANGP00000018341
Ashbya gossypii (Ago) ago3910 AFR717W
Caenorhabditis elegans (Cel) cel18768 Y42H9AR.1
(CE25278;
WBGene00021536)
Candida glabrata (Cgl) cgl1257 CAGL0F00583g
Cryptococcus neoformans (Cne) cne4372 177.m03124
Dictyostelium discoideum (Ddi) ddi10034 DDB0191849
Debaryomyces hansenii (Dha) dha977 DEHA0B06710g
Drosophila melanogaster (Dme) dme10306 CG7809-PA
(FBgn0036919)
Danio rerio (Dre) dre8721 ENSDARP00000017335
Encephalitozoon cuniculi (Ecu) ecu1699 19075062
Takifugu rubripes (Fru) fru8767 SINFRUP00000137886
Takifugu rubripes (Fru) fru27574 SINFRUP00000140997
Takifugu rubripes (Fru) fru182 SINFRUP00000149373
Takifugu rubripes (Fru) fru26478 SINFRUP00000150699
Gallus gallus (Gga) gga9370 ENSGALP00000009699
(GORASP1)
Q5ZK65
Gallus gallus (Gga) gga21543 ENSGALP00000015596
(GORASP2)
Homo sapiens (Hsa) hsa18848 ENSP00000234160
(GORASP2)
Q9H8Y8-1
Homo sapiens (Hsa) hsa22273 ENSP00000313869
(GORASP1)
Q9BQQ3-1
Kluyveromyces lactis (Kla) kla1244 KLLA0C01133g
Mus musculus (Mmu) mmu14753 ENSMUSP00000028509
(MGI:2135962)
Q99JX3-1
Mus musculus (Mmu) mmu28470 ENSMUSP00000035099
(MGI:1921748)
Q91X51
Neurospora crassa (Ncr) ncr8984 NCU09217.2
Plasmodium falciparum (Pfa) pfa389 PF10_0168
Rattus norvegicus (Rno) rno29459 ENSRNOP00000024408
(RGD:621122)
A0JN16
Rattus norvegicus (Rno) rno18746 ENSRNOP00000036881
(RGD:619911)
Q68G33
Saccharomyces cerevisiae (Sce) sce1584 YDR517W
(S000002925)
Schizosaccharomyces pombe (Spo) spo3954 SPAC1D4.02c Q10149
Yarrowia lipolytica (Yli) yli3982 YALI0E03014g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000139 Golgi membrane C
ISS
DmeFBgn0036919
GO:0005634 nucleus C
IDA
SpoSPAC1D4.02c
GO:0005737 cytoplasm C
IDA
SceS000002925
ISS
SpoSPAC1D4.02c
GO:0005783 endoplasmic reticulum C
IDA
DmeFBgn0036919
GO:0005794 Golgi apparatus C
IDA
MmuMGI:1921748
ISO
MmuMGI:2135962
ISS
SpoSPAC1D4.02c
GO:0005795 Golgi stack C
IDA
DmeFBgn0036919
GO:0005797 Golgi medial cisterna C
ISO
MmuMGI:2135962
GO:0005798 Golgi-associated vesicle C
IDA
DmeFBgn0036919
GO:0005801 cis-Golgi network C
IDA
SceS000002925
IMP
SceS000002925
GO:0005829 cytosol C
IDA
SpoSPAC1D4.02c
GO:0030127 COPII vesicle coat C
IDA
SceS000002925
GO:0032153 cell division site C
IDA
SpoSPAC1D4.02c
GO:0051286 cell tip C
IDA
SpoSPAC1D4.02c
GO:0003674 molecular_function F
ND
MmuMGI:1921748
MGI:2135962
SceS000002925
SpoSPAC1D4.02c
GO:0006888 ER to Golgi vesicle-mediated transport P
IGI
SceS000002925
IMP
SceS000002925
ISS
SpoSPAC1D4.02c
GO:0007030 Golgi organization P
IMP
DmeFBgn0036919
ISO
MmuMGI:1921748
MGI:2135962
ISS
SceS000002925
SpoSPAC1D4.02c
GO:0007165 signal transduction P
NAS
SpoSPAC1D4.02c
GO:0008150 biological_process P
ND
PfaPF10_0168
GO:0009306 protein secretion P
IMP
SceS000002925

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPAC1D4.02c
(Q10149)
YDR517W
(S000002925)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPAC1D4.02c
GO:0005737 cytoplasm C
IDA
SceS000002925
ISS
SpoSPAC1D4.02c
GO:0005794 Golgi apparatus C
ISS
SpoSPAC1D4.02c
GO:0005801 cis-Golgi network C
IDA
SceS000002925
IMP
SceS000002925
GO:0005829 cytosol C
IDA
SpoSPAC1D4.02c
GO:0030127 COPII vesicle coat C
IDA
SceS000002925
GO:0032153 cell division site C
IDA
SpoSPAC1D4.02c
GO:0051286 cell tip C
IDA
SpoSPAC1D4.02c
GO:0003674 molecular_function F
ND
SceS000002925
SpoSPAC1D4.02c
GO:0006888 ER to Golgi vesicle-mediated transport P
IGI
SceS000002925
IMP
SceS000002925
ISS
SpoSPAC1D4.02c
GO:0007030 Golgi organization P
ISS
SceS000002925
SpoSPAC1D4.02c
GO:0007165 signal transduction P
NAS
SpoSPAC1D4.02c
GO:0009306 protein secretion P
IMP
SceS000002925

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GO info in one table:

s.khadayate@ucl.ac.uk