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Search term: YDR518W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name EUG1
SGD link S000002926
Alternative ID YDR518W
Description Protein disulfide isomerase of the endoplasmic reticulum lumen, function overlaps with that of Pdi1p; may interact with nascent polypeptides in the ER
Synonyms YDR518W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

Search for gene by ID or name:

Query species:

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0190 ACDHYPE

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Protein disulfide isomerase (prolyl 4-hydroxylase beta subunit)

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g21750 GI:15219086
Arabidopsis thaliana (Ath) At1g35620 GI:15219666
Arabidopsis thaliana (Ath) At1g52260 GI:15218191
Arabidopsis thaliana (Ath) At1g77510 GI:15223975
Arabidopsis thaliana (Ath) At3g16110 GI:15233287
Arabidopsis thaliana (Ath) At3g54960 GI:15233138
Arabidopsis thaliana (Ath) At3g62510 GI:15228782
Arabidopsis thaliana (Ath) At5g60640 GI:15239391
Caenorhabditis elegans (Cel) CE00073 GI:17552178
Caenorhabditis elegans (Cel) CE00897
(WBGene00003962)		 GI:17554386 Q17967
Caenorhabditis elegans (Cel) CE03972
(WBGene00003963)		 GI:17569137 Q17770
Caenorhabditis elegans (Cel) CE11570
(WBGene00003964)		 GI:17507915 O17908
Drosophila melanogaster (Dme) 7294310
(FBgn0014002)		 GI:17647799
Drosophila melanogaster (Dme) 7303555 GI:7303555
Homo sapiens (Hsa) Hs20070125
(P4HB)		 GI:20070125 P07237
Homo sapiens (Hsa) Hs21361511 GI:14042477 Q6PKC3
Homo sapiens (Hsa) Hs21361657 GI:2507461 P30101
Homo sapiens (Hsa) Hs4758304
(PDIA4)		 GI:4758304 P13667
Homo sapiens (Hsa) Hs5803119 GI:5803119
Homo sapiens (Hsa) HsM20127473 GI:20127473
Homo sapiens (Hsa) HsM7705698 GI:7705698
Saccharomyces cerevisiae (Sce) YCL043c
(S000000548)		 GI:6319806 P17967
Saccharomyces cerevisiae (Sce) YDR518w
(S000002926)		 GI:6320726 P32474
Schizosaccharomyces pombe (Spo) SPAC1F5.02 GI:19113783 Q10057
Encephalitozoon cuniculi (Ecu) ECU09g1560 GI:19173277
Arabidopsis thaliana (Ath) At1g21750 GI:15219086
Arabidopsis thaliana (Ath) At1g35620 GI:15219666
Arabidopsis thaliana (Ath) At1g52260 GI:15218191
Arabidopsis thaliana (Ath) At1g77510 GI:15223975
Arabidopsis thaliana (Ath) At3g16110 GI:15233287
Arabidopsis thaliana (Ath) At3g54960 GI:15233138
Arabidopsis thaliana (Ath) At3g62510 GI:15228782
Arabidopsis thaliana (Ath) At5g60640 GI:15239391
Caenorhabditis elegans (Cel) CE00073 GI:17552178
Caenorhabditis elegans (Cel) CE00897
(WBGene00003962)		 GI:17554386 Q17967
Caenorhabditis elegans (Cel) CE03972
(WBGene00003963)		 GI:17569137 Q17770
Caenorhabditis elegans (Cel) CE11570
(WBGene00003964)		 GI:17507915 O17908
Drosophila melanogaster (Dme) 7294310
(FBgn0014002)		 GI:17647799
Drosophila melanogaster (Dme) 7303555 GI:7303555
Homo sapiens (Hsa) Hs20070125
(P4HB)		 GI:20070125 P07237
Homo sapiens (Hsa) Hs21361511 GI:14042477 Q6PKC3
Homo sapiens (Hsa) Hs21361657 GI:2507461 P30101
Homo sapiens (Hsa) Hs4758304
(PDIA4)		 GI:4758304 P13667
Homo sapiens (Hsa) Hs5803119 GI:5803119
Homo sapiens (Hsa) HsM20127473 GI:20127473
Homo sapiens (Hsa) HsM7705698 GI:7705698
Saccharomyces cerevisiae (Sce) YCL043c
(S000000548)		 GI:6319806 P17967
Saccharomyces cerevisiae (Sce) YDR518w
(S000002926)		 GI:6320726 P32474
Schizosaccharomyces pombe (Spo) SPAC1F5.02 GI:19113783 Q10057
Encephalitozoon cuniculi (Ecu) ECU09g1560 GI:19173277
Arabidopsis thaliana (Ath) At1g21750 GI:15219086
Arabidopsis thaliana (Ath) At1g35620 GI:15219666
Arabidopsis thaliana (Ath) At1g52260 GI:15218191
Arabidopsis thaliana (Ath) At1g77510 GI:15223975
Arabidopsis thaliana (Ath) At3g16110 GI:15233287
Arabidopsis thaliana (Ath) At3g54960 GI:15233138
Arabidopsis thaliana (Ath) At3g62510 GI:15228782
Arabidopsis thaliana (Ath) At5g60640 GI:15239391
Caenorhabditis elegans (Cel) CE00073 GI:17552178
Caenorhabditis elegans (Cel) CE00897
(WBGene00003962)		 GI:17554386 Q17967
Caenorhabditis elegans (Cel) CE03972
(WBGene00003963)		 GI:17569137 Q17770
Caenorhabditis elegans (Cel) CE11570
(WBGene00003964)		 GI:17507915 O17908
Drosophila melanogaster (Dme) 7294310
(FBgn0014002)		 GI:17647799
Drosophila melanogaster (Dme) 7303555 GI:7303555
Homo sapiens (Hsa) Hs20070125
(P4HB)		 GI:20070125 P07237
Homo sapiens (Hsa) Hs21361511 GI:14042477 Q6PKC3
Homo sapiens (Hsa) Hs21361657 GI:2507461 P30101
Homo sapiens (Hsa) Hs4758304
(PDIA4)		 GI:4758304 P13667
Homo sapiens (Hsa) Hs5803119 GI:5803119
Homo sapiens (Hsa) HsM20127473 GI:20127473
Homo sapiens (Hsa) HsM7705698 GI:7705698
Saccharomyces cerevisiae (Sce) YCL043c
(S000000548)		 GI:6319806 P17967
Saccharomyces cerevisiae (Sce) YDR518w
(S000002926)		 GI:6320726 P32474
Schizosaccharomyces pombe (Spo) SPAC1F5.02 GI:19113783 Q10057
Encephalitozoon cuniculi (Ecu) ECU09g1560 GI:19173277


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000326 protein storage vacuole C
IDA
AthAt1g21750
GO:0000327 lytic vacuole within protein storage
vacuole		 C
IDA
AthAt1g21750
GO:0005575 cellular_component C
ND
AthAt3g62510
GO:0005576 extracellular region C
NAS
HsaP4HB
GO:0005737 cytoplasm C
IDA
DmeFBgn0014002
GO:0005739 mitochondrion C
IDA
AthAt5g60640
GO:0005773 vacuole C
IDA
AthAt1g21750
GO:0005783 endoplasmic reticulum C
IDA
AthAt1g77510
At1g35620
At3g16110
At5g60640
At1g52260
At1g21750
At3g54960
CelWBGene00003963
DmeFBgn0014002
HsaP4HB
SceS000002926
SpoSPAC1F5.02
GO:0005788 endoplasmic reticulum lumen C
IDA
SceS000000548
ISS
SpoSPAC1F5.02
NAS
DmeFBgn0014002
GO:0005793 ER-Golgi intermediate compartment C
IDA
HsaP4HB
GO:0005811 lipid particle C
IDA
DmeFBgn0014002
GO:0005886 plasma membrane C
IDA
AthAt1g35620
At3g54960
At1g77510
At5g60640
GO:0009505 plant-type cell wall C
IDA
AthAt1g35620
At1g21750
GO:0009507 chloroplast C
IDA
AthAt1g21750
At5g60640
At3g54960
At1g77510
GO:0009579 thylakoid C
IDA
AthAt1g21750
GO:0009986 cell surface C
IDA
HsaP4HB
GO:0016020 membrane C
IDA
AthAt1g21750
GO:0043025 neuronal cell body C
IDA
DmeFBgn0014002
GO:0045169 fusome C
IDA
DmeFBgn0014002
GO:0048471 perinuclear region of cytoplasm C
IDA
DmeFBgn0014002
GO:0060187 cell pole C
IDA
DmeFBgn0014002
GO:0070732 spindle envelope C
IDA
DmeFBgn0014002
GO:0003674 molecular_function F
ND
AthAt3g62510
GO:0003756 protein disulfide isomerase activity F
IDA
CelWBGene00003962
WBGene00003963
WBGene00003964
SceS000000548
S000002926
IGI
SceS000002926
IMP
SceS000000548
S000002926
ISS
AthAt1g35620
At3g16110
At3g54960
At5g60640
At1g21750
At1g52260
At1g77510
DmeFBgn0014002
SceS000002926
SpoSPAC1F5.02
GO:0003810 protein-glutamine gamma-glutamyltransferase
activity		 F
IDA
CelWBGene00003962
WBGene00003963
WBGene00003964
GO:0004656 procollagen-proline 4-dioxygenase
activity		 F
IDA
HsaP4HB
GO:0005515 protein binding F
IPI
HsaP4HB
PDIA4
GO:0015035 protein disulfide oxidoreductase
activity		 F
IDA
SceS000000548
S000002926
IGI
SceS000002926
ISS
SceS000002926
SpoSPAC1F5.02
GO:0000003 reproduction P
IMP
CelWBGene00003963
GO:0001703 gastrulation with mouth forming
first		 P
IMP
CelWBGene00003963
GO:0002119 nematode larval development P
IMP
CelWBGene00003963
GO:0006457 protein folding P
IGI
SceS000002926
IMP
SceS000000548
ISS
DmeFBgn0014002
SpoSPAC1F5.02
NAS
DmeFBgn0014002
GO:0006979 response to oxidative stress P
IDA
AthAt5g60640
GO:0007369 gastrulation P
IMP
CelWBGene00003963
GO:0008150 biological_process P
ND
AthAt3g62510
GO:0008360 regulation of cell shape P
IGI
CelWBGene00003964
GO:0009306 protein secretion P
TAS
HsaPDIA4
GO:0009651 response to salt stress P
IEP
AthAt1g21750
At1g77510
GO:0009790 embryo development P
IMP
AthAt1g21750
CelWBGene00003963
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00003963
GO:0010043 response to zinc ion P
IEP
AthAt1g21750
GO:0010171 body morphogenesis P
IGI
CelWBGene00003964
IMP
CelWBGene00003963
GO:0018401 peptidyl-proline hydroxylation to
4-hydroxy-L-proline		 P
IDA
HsaP4HB
GO:0018991 oviposition P
IGI
CelWBGene00003964
GO:0034976 response to endoplasmic reticulum
stress		 P
IEP
AthAt3g54960
At1g21750
At1g77510
GO:0035121 tail morphogenesis P
IGI
CelWBGene00003964
GO:0040002 collagen and cuticulin-based cuticle
development		 P
IGI
CelWBGene00003964
IMP
CelWBGene00003964
GO:0040007 growth P
IMP
CelWBGene00003963
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00003962
WBGene00003963
GO:0040011 locomotion P
IMP
CelWBGene00003963
GO:0040017 positive regulation of locomotion P
IMP
CelWBGene00003963
GO:0040018 positive regulation of multicellular organism
growth		 P
IMP
CelWBGene00003964
GO:0040019 positive regulation of embryonic
development		 P
IGI
CelWBGene00003964
GO:0043067 regulation of programmed cell death P
IMP
AthAt1g21750
GO:0044262 cellular carbohydrate metabolic
process		 P
RCA
SceS000000548
GO:0045138 tail tip morphogenesis P
IGI
CelWBGene00003964
GO:0045454 cell redox homeostasis P
RCA
SceS000000548
GO:0046686 response to cadmium ion P
IEP
AthAt1g77510
GO:0048316 seed development P
IMP
AthAt1g21750

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_226

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga9615 ENSANGP00000011666
Anopheles gambiae (Aga) aga9614 ENSANGP00000026077
Anopheles gambiae (Aga) aga2817 ENSANGP00000027211
Ashbya gossypii (Ago) ago3911 AFR718W
Arabidopsis thaliana (Ath) ath2333 At1g21750.1
Arabidopsis thaliana (Ath) ath2334 At1g21750.2
Arabidopsis thaliana (Ath) ath7090 At1g77510.1
Arabidopsis thaliana (Ath) ath16871 At3g54960.1
Arabidopsis thaliana (Ath) ath28149 At5g60640.1
Arabidopsis thaliana (Ath) ath28150 At5g60640.2
Caenorhabditis elegans (Cel) cel1373 C07A12.4a
(CE03972;
WBGene00003963)
Caenorhabditis elegans (Cel) cel1958 C14B9.2
(CE30601;
WBGene00015752)
Caenorhabditis elegans (Cel) cel11247 H06O01.1
(CE11570;
WBGene00003964)
Caenorhabditis elegans (Cel) cel20705 Y73B6BL.12
(CE26290;
WBGene00022236)
Candida glabrata (Cgl) cgl235 CAGL0B00704g
Candida glabrata (Cgl) cgl2141 CAGL0H01727g
Cryptococcus neoformans (Cne) cne1778 164.m02186
Dictyostelium discoideum (Ddi) ddi13665 DDB0231409
Debaryomyces hansenii (Dha) dha4340 DEHA0E25036g
Drosophila melanogaster (Dme) dme9575 CG6988-PA
(FBgn0014002)
Drosophila melanogaster (Dme) dme4559 CG8983-PA
(FBgn0033663)
Drosophila melanogaster (Dme) dme4560 CG8983-PB
(FBgn0033663)
Danio rerio (Dre) dre31489 ENSDARP00000009108
Danio rerio (Dre) dre16112 ENSDARP00000018458
(pdia4)		 Q6P3I1
Danio rerio (Dre) dre7333 ENSDARP00000023877
(zgc:77086)		 Q6NXB9
Danio rerio (Dre) dre10131 ENSDARP00000041610
Danio rerio (Dre) dre15104 ENSDARP00000042651
Danio rerio (Dre) dre15103 ENSDARP00000047611
Danio rerio (Dre) dre10148 ENSDARP00000048151
Danio rerio (Dre) dre10130 ENSDARP00000049019
(LOC554866)		 Q1LXD1
Encephalitozoon cuniculi (Ecu) ecu1428 19173277
Takifugu rubripes (Fru) fru2502 SINFRUP00000127860
Takifugu rubripes (Fru) fru22078 SINFRUP00000132913
Takifugu rubripes (Fru) fru22077 SINFRUP00000132914
Takifugu rubripes (Fru) fru9780 SINFRUP00000137354
Takifugu rubripes (Fru) fru31250 SINFRUP00000138984
Takifugu rubripes (Fru) fru22079 SINFRUP00000165919
Takifugu rubripes (Fru) fru31248 SINFRUP00000167897
Takifugu rubripes (Fru) fru2504 SINFRUP00000169136
Takifugu rubripes (Fru) fru31249 SINFRUP00000170679
Takifugu rubripes (Fru) fru2503 SINFRUP00000171108
Gallus gallus (Gga) gga16476 ENSGALP00000011689
(P4HB)		 P09102
Gallus gallus (Gga) gga4258 ENSGALP00000013574
(PDIA3)		 Q8JG64
Gallus gallus (Gga) gga10327 ENSGALP00000020268
(PDIA4)		 Q5ZK20
Gallus gallus (Gga) gga10328 ENSGALP00000020269
(LOC776359)
Homo sapiens (Hsa) hsa11337 ENSP00000219406
(PDIA2)		 Q13087
Homo sapiens (Hsa) hsa29640 ENSP00000286091
(PDIA4)		 P13667
Homo sapiens (Hsa) hsa10558 ENSP00000300289
(PDIA3)		 P30101
Homo sapiens (Hsa) hsa14522 ENSP00000327801
(P4HB)		 P07237
Homo sapiens (Hsa) hsa14618 ENSP00000344468
(SDC3)		 O75056
Kluyveromyces lactis (Kla) kla1243 KLLA0C01111g
Mus musculus (Mmu) mmu5322 ENSMUSP00000026122
(MGI:97464)		 Q3TF72
Mus musculus (Mmu) mmu15360 ENSMUSP00000028683
(MGI:95834)		 P27773
Mus musculus (Mmu) mmu11204 ENSMUSP00000035584
(MGI:1916441)
Mus musculus (Mmu) mmu21801 ENSMUSP00000076521
(MGI:104864)		 P08003
Neurospora crassa (Ncr) ncr8990 NCU09223.2
Oryza sativa (Osa) osa58018 6455.m00167
Oryza sativa (Osa) osa63666 6742.m00179
Oryza sativa (Osa) osa63706 6742.m00199
Plasmodium falciparum (Pfa) pfa1982 MAL8P1.17
Rattus norvegicus (Rno) rno21198 ENSRNOP00000008728
(RGD:619835)		 P38659
Rattus norvegicus (Rno) rno19560 ENSRNOP00000020478
(RGD:68430)		 P11598
Rattus norvegicus (Rno) rno4716 ENSRNOP00000027726
(RGD:1305164)
Rattus norvegicus (Rno) rno4717 ENSRNOP00000046554
Saccharomyces cerevisiae (Sce) sce624 YCL043C
(S000000548)
Saccharomyces cerevisiae (Sce) sce1585 YDR518W
(S000002926)
Schizosaccharomyces pombe (Spo) spo1445 SPAC1F5.02 Q10057
Yarrowia lipolytica (Yli) yli3983 YALI0E03036g