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Search term: YDR519W


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name FPR2
SGD link S000002927
Alternative ID YDR519W
Description Membrane-bound peptidyl-prolyl cis-trans isomerase (PPIase), binds to the drugs FK506 and rapamycin; expression pattern suggests possible involvement in ER protein trafficking
Synonyms YDR519W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0549 ACDHY--

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING FKBP-type peptidyl-prolyl cis-trans isomerase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At3g25220 GI:2129622
Arabidopsis thaliana (Ath) At5g45680 GI:15242472
Arabidopsis thaliana (Ath) At5g48580 GI:15239019
Caenorhabditis elegans (Cel) CE05813
(WBGene00001426)
GI:17540882 Q20107
Caenorhabditis elegans (Cel) CE07921
(WBGene00001428)
GI:17561778 O16309
Caenorhabditis elegans (Cel) CE08912
(WBGene00001430)
GI:17506167 P91180
Caenorhabditis elegans (Cel) CE23446
(WBGene00001429)
GI:17561780 Q23338
Caenorhabditis elegans (Cel) CE26851
(WBGene00001432)
GI:17507841 O61826
Caenorhabditis elegans (Cel) CE27878 GI:17506169 P91180
Drosophila melanogaster (Dme) 7291296
(FBgn0010470)
GI:17352457 Q9V3V2
Drosophila melanogaster (Dme) 7299486 GI:7299486
Homo sapiens (Hsa) Hs17149842 GI:17149842 P26885
Homo sapiens (Hsa) Hs18550547 GI:18550547
Homo sapiens (Hsa) Hs20540566 GI:20540566
Homo sapiens (Hsa) Hs21361895 GI:12231182 Q96AY3
Homo sapiens (Hsa) Hs7706131
(FKBP11)
GI:7706131 Q9NYL4
Homo sapiens (Hsa) Hs8923659
(FKBP14)
GI:8923659 Q9NWM8
Homo sapiens (Hsa) HsM11345476 GI:11345476
Saccharomyces cerevisiae (Sce) YDR519w
(S000002927)
GI:6320727 P32472
Arabidopsis thaliana (Ath) At3g25220 GI:2129622
Arabidopsis thaliana (Ath) At5g45680 GI:15242472
Arabidopsis thaliana (Ath) At5g48580 GI:15239019
Caenorhabditis elegans (Cel) CE05813
(WBGene00001426)
GI:17540882 Q20107
Caenorhabditis elegans (Cel) CE07921
(WBGene00001428)
GI:17561778 O16309
Caenorhabditis elegans (Cel) CE08912
(WBGene00001430)
GI:17506167 P91180
Caenorhabditis elegans (Cel) CE23446
(WBGene00001429)
GI:17561780 Q23338
Caenorhabditis elegans (Cel) CE26851
(WBGene00001432)
GI:17507841 O61826
Caenorhabditis elegans (Cel) CE27878 GI:17506169 P91180
Drosophila melanogaster (Dme) 7291296
(FBgn0010470)
GI:17352457 Q9V3V2
Drosophila melanogaster (Dme) 7299486 GI:7299486
Homo sapiens (Hsa) Hs17149842 GI:17149842 P26885
Homo sapiens (Hsa) Hs18550547 GI:18550547
Homo sapiens (Hsa) Hs20540566 GI:20540566
Homo sapiens (Hsa) Hs21361895 GI:12231182 Q96AY3
Homo sapiens (Hsa) Hs7706131
(FKBP11)
GI:7706131 Q9NYL4
Homo sapiens (Hsa) Hs8923659
(FKBP14)
GI:8923659 Q9NWM8
Homo sapiens (Hsa) HsM11345476 GI:11345476
Saccharomyces cerevisiae (Sce) YDR519w
(S000002927)
GI:6320727 P32472


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005773 vacuole C
IDA
AthAt5g48580
GO:0005789 endoplasmic reticulum membrane C
IEP
SceS000002927
ISS
SceS000002927
GO:0009507 chloroplast C
IDA
AthAt5g45680
GO:0009543 chloroplast thylakoid lumen C
IDA
AthAt5g45680
ISS
AthAt5g48580
At5g45680
GO:0031977 thylakoid lumen C
IDA
AthAt5g45680
GO:0003755 peptidyl-prolyl cis-trans isomerase
activity
F
IDA
AthAt5g45680
ISS
AthAt5g45680
At3g25220
At5g48580
DmeFBgn0010470
SceS000002927
GO:0005528 FK506 binding F
IDA
SceS000002927
ISS
AthAt5g48580
At5g45680
At3g25220
DmeFBgn0010470
GO:0002121 inter-male aggressive behavior P
IMP
DmeFBgn0010470
GO:0008150 biological_process P
ND
SceS000002927
GO:0008340 determination of adult lifespan P
IMP
CelWBGene00001428
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00001429

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
40604

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) FKBP2 GI:206725530
Pan troglodytes (Ptr) FKBP2 GI:114638287
Canis familiaris (Cfa) FKBP2 GI:73983269
Mus musculus (Mmu) Fkbp2
(MGI:95542)
GI:6679805 P45878
Rattus norvegicus (Rno) Fkbp2 GI:62641808
Drosophila melanogaster (Dme) CG14715
(FBgn0037930)
GI:21356629
Anopheles gambiae (Aga) AgaP_AGAP003134 GI:158291297
Caenorhabditis elegans (Cel) fkb-1
(CE05813;
WBGene00001426)
GI:17540882 Q20107
Saccharomyces cerevisiae (Sce) FPR2
(S000002927)
GI:6320727 P32472
Kluyveromyces lactis (Kla) KLLA0C01045g GI:50304571
Magnaporthe grisea (Mgr) MGG_07234 GI:145612595
Neurospora crassa (Ncr) NCU02455.1 GI:32421575
Arabidopsis thaliana (Ath) FKBP15-2 GI:15239019
Arabidopsis thaliana (Ath) FKBP15-1 GI:18404471
Oryza sativa (Osa) Os01g0915800 GI:115441819


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
MmuMGI:95542
GO:0005773 vacuole C
IDA
AthFKBP15-2
GO:0005789 endoplasmic reticulum membrane C
IEP
SceS000002927
ISS
SceS000002927
GO:0009543 chloroplast thylakoid lumen C
ISS
AthFKBP15-2
GO:0003674 molecular_function F
ND
MmuMGI:95542
GO:0003755 peptidyl-prolyl cis-trans isomerase
activity
F
ISS
AthFKBP15-1
FKBP15-2
DmeFBgn0037930
SceS000002927
GO:0005515 protein binding F
IPI
HsaFKBP2
GO:0005528 FK506 binding F
IDA
SceS000002927
ISS
AthFKBP15-2
FKBP15-1
DmeFBgn0037930
TAS
HsaFKBP2
GO:0008150 biological_process P
ND
MmuMGI:95542
SceS000002927

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_3584

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Anopheles gambiae (Aga) aga5419 ENSANGP00000016706
Arabidopsis thaliana (Ath) ath14849 At3g25220.1
Arabidopsis thaliana (Ath) ath26760 At5g48580.1
Caenorhabditis elegans (Cel) cel8315 F36H1.1
(CE05813;
WBGene00001426)
Candida glabrata (Cgl) cgl2140 CAGL0H01705g
Cryptococcus neoformans (Cne) cne3073 167.m03377
Dictyostelium discoideum (Ddi) ddi6741 DDB0205305
Debaryomyces hansenii (Dha) dha3968 DEHA0E16434g
Drosophila melanogaster (Dme) dme12093 CG14715-PA
(FBgn0037930)
Danio rerio (Dre) dre13804 ENSDARP00000023674
Escherichia coli (Eco) eco4050 49176472
Takifugu rubripes (Fru) fru32670 SINFRUP00000128779
Takifugu rubripes (Fru) fru10918 SINFRUP00000157280
Homo sapiens (Hsa) hsa5869 ENSP00000310935
(FKBP2)
P26885
Homo sapiens (Hsa) hsa5870 ENSP00000311201
Kluyveromyces lactis (Kla) kla1240 KLLA0C01045g
Mus musculus (Mmu) mmu13232 ENSMUSP00000066839
(MGI:95542)
P45878
Oryza sativa (Osa) osa7942 2581.m00105
Oryza sativa (Osa) osa33927 4657.m00135
Rattus norvegicus (Rno) rno3589 ENSRNOP00000028725
(RGD:1560660)
Saccharomyces cerevisiae (Sce) sce1586 YDR519W
(S000002927)
Yarrowia lipolytica (Yli) yli665 YALI0A19602g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
MmuMGI:95542
GO:0005773 vacuole C
IDA
AthAt5g48580
GO:0005789 endoplasmic reticulum membrane C
IEP
SceS000002927
ISS
SceS000002927
GO:0009543 chloroplast thylakoid lumen C
ISS
AthAt5g48580
GO:0003674 molecular_function F
ND
MmuMGI:95542
GO:0003755 peptidyl-prolyl cis-trans isomerase
activity
F
ISS
AthAt3g25220
At5g48580
DmeFBgn0037930
SceS000002927
GO:0005528 FK506 binding F
IDA
SceS000002927
ISS
AthAt5g48580
At3g25220
DmeFBgn0037930
GO:0008150 biological_process P
ND
MmuMGI:95542
SceS000002927

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