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Search term: YDR524C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name AGE1
SGD link S000002932
Alternative ID YDR524C
Description ADP-ribosylation factor (ARF) GTPase activating protein (GAP) effector, involved in the secretory and endocytic pathways; contains C2C2H2 cysteine/histidine motif
Synonyms YDR524C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0521 ACDHYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Putative GTPase activating proteins (GAPs)

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g10870 GI:15220230
Arabidopsis thaliana (Ath) At1g60860 GI:15219822
Arabidopsis thaliana (Ath) At5g13300 GI:15240595
Arabidopsis thaliana (Ath) At5g61980 GI:15240398
Caenorhabditis elegans (Cel) CE25223 GI:17536945
Caenorhabditis elegans (Cel) CE28110
(WBGene00000565)		 GI:17536947
Drosophila melanogaster (Dme) 7300962
(FBgn0039056)		 GI:17738139 Q7KS50
Drosophila melanogaster (Dme) 7304095 GI:7304095
Homo sapiens (Hsa) Hs14755125_1 GI:14755125
Homo sapiens (Hsa) Hs16945966 GI:16945966
Homo sapiens (Hsa) Hs17977656 GI:17977656
Homo sapiens (Hsa) Hs19923540
(ASAP3)		 GI:19923540 Q9NXH7
Homo sapiens (Hsa) Hs22044335 GI:22044335
Homo sapiens (Hsa) Hs22047380 GI:22047380
Homo sapiens (Hsa) Hs22047742 GI:22047742
Homo sapiens (Hsa) Hs4502249
(ASAP2)		 GI:4502249 Q8N282
Homo sapiens (Hsa) Hs6912242_1
(APPL1)		 GI:6912242 Q9UKG1
Homo sapiens (Hsa) Hs7661880
(ACAP1)		 GI:7661880 Q15027
Homo sapiens (Hsa) Hs8922577 GI:8922577
Saccharomyces cerevisiae (Sce) YDR524c
(S000002932)		 GI:6320732 Q04412
Schizosaccharomyces pombe (Spo) SPAC26A3.10 GI:19115065 Q10165
Schizosaccharomyces pombe (Spo) SPBC17G9.08c GI:19112689 Q9UUE2
Arabidopsis thaliana (Ath) At1g10870 GI:15220230
Arabidopsis thaliana (Ath) At1g60860 GI:15219822
Arabidopsis thaliana (Ath) At5g13300 GI:15240595
Arabidopsis thaliana (Ath) At5g61980 GI:15240398
Caenorhabditis elegans (Cel) CE25223 GI:17536945
Caenorhabditis elegans (Cel) CE28110
(WBGene00000565)		 GI:17536947
Drosophila melanogaster (Dme) 7300962
(FBgn0039056)		 GI:17738139 Q7KS50
Drosophila melanogaster (Dme) 7304095 GI:7304095
Homo sapiens (Hsa) Hs14755125_1 GI:14755125
Homo sapiens (Hsa) Hs16945966 GI:16945966
Homo sapiens (Hsa) Hs17977656 GI:17977656
Homo sapiens (Hsa) Hs19923540
(ASAP3)		 GI:19923540 Q9NXH7
Homo sapiens (Hsa) Hs22044335 GI:22044335
Homo sapiens (Hsa) Hs22047380 GI:22047380
Homo sapiens (Hsa) Hs22047742 GI:22047742
Homo sapiens (Hsa) Hs4502249
(ASAP2)		 GI:4502249 Q8N282
Homo sapiens (Hsa) Hs6912242_1
(APPL1)		 GI:6912242 Q9UKG1
Homo sapiens (Hsa) Hs7661880
(ACAP1)		 GI:7661880 Q15027
Homo sapiens (Hsa) Hs8922577 GI:8922577
Saccharomyces cerevisiae (Sce) YDR524c
(S000002932)		 GI:6320732 Q04412
Schizosaccharomyces pombe (Spo) SPAC26A3.10 GI:19115065 Q10165
Schizosaccharomyces pombe (Spo) SPBC17G9.08c GI:19112689 Q9UUE2
Arabidopsis thaliana (Ath) At1g10870 GI:15220230
Arabidopsis thaliana (Ath) At1g60860 GI:15219822
Arabidopsis thaliana (Ath) At5g13300 GI:15240595
Arabidopsis thaliana (Ath) At5g61980 GI:15240398
Caenorhabditis elegans (Cel) CE25223 GI:17536945
Caenorhabditis elegans (Cel) CE28110
(WBGene00000565)		 GI:17536947
Drosophila melanogaster (Dme) 7300962
(FBgn0039056)		 GI:17738139 Q7KS50
Drosophila melanogaster (Dme) 7304095 GI:7304095
Homo sapiens (Hsa) Hs14755125_1 GI:14755125
Homo sapiens (Hsa) Hs16945966 GI:16945966
Homo sapiens (Hsa) Hs17977656 GI:17977656
Homo sapiens (Hsa) Hs19923540
(ASAP3)		 GI:19923540 Q9NXH7
Homo sapiens (Hsa) Hs22044335 GI:22044335
Homo sapiens (Hsa) Hs22047380 GI:22047380
Homo sapiens (Hsa) Hs22047742 GI:22047742
Homo sapiens (Hsa) Hs4502249
(ASAP2)		 GI:4502249 Q8N282
Homo sapiens (Hsa) Hs6912242_1
(APPL1)		 GI:6912242 Q9UKG1
Homo sapiens (Hsa) Hs7661880
(ACAP1)		 GI:7661880 Q15027
Homo sapiens (Hsa) Hs8922577 GI:8922577
Saccharomyces cerevisiae (Sce) YDR524c
(S000002932)		 GI:6320732 Q04412
Schizosaccharomyces pombe (Spo) SPAC26A3.10 GI:19115065 Q10165
Schizosaccharomyces pombe (Spo) SPBC17G9.08c GI:19112689 Q9UUE2


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
HsaAPPL1
GO:0005737 cytoplasm C
IC
HsaAPPL1
IDA
SceS000002932
GO:0005792 microsome C
IDA
HsaAPPL1
GO:0005829 cytosol C
IDA
AthAt5g13300
HsaAPPL1
SpoSPAC26A3.10
SPBC17G9.08c
GO:0005886 plasma membrane C
IDA
AthAt5g13300
SpoSPBC17G9.08c
GO:0010008 endosome membrane C
IDA
HsaAPPL1
GO:0012506 vesicle membrane C
IDA
HsaAPPL1
GO:0016581 NuRD complex C
IDA
HsaAPPL1
GO:0030139 endocytic vesicle C
IDA
AthAt5g61980
GO:0030140 trans-Golgi network transport vesicle C
IDA
AthAt5g13300
GO:0032153 cell division site C
IDA
SpoSPAC26A3.10
GO:0051286 cell tip C
IDA
SpoSPAC26A3.10
GO:0005096 GTPase activator activity F
ISS
SpoSPAC26A3.10
SPBC17G9.08c
GO:0005515 protein binding F
IPI
HsaAPPL1
ACAP1
ASAP2
GO:0005543 phospholipid binding F
IDA
SpoSPBC17G9.08c
GO:0008047 enzyme activator activity F
TAS
HsaASAP2
GO:0008060 ARF GTPase activator activity F
IDA
AthAt5g13300
SceS000002932
IGI
SceS000002932
ISS
DmeFBgn0039056
SceS000002932
GO:0035091 phosphoinositide binding F
IDA
AthAt5g13300
GO:0043422 protein kinase B binding F
IPI
HsaAPPL1
GO:0002119 nematode larval development P
IMP
CelWBGene00000565
GO:0006886 intracellular protein transport P
NAS
SpoSPAC26A3.10
SPBC17G9.08c
GO:0006888 ER to Golgi vesicle-mediated transport P
IGI
SceS000002932
ISS
SceS000002932
GO:0006891 intra-Golgi vesicle-mediated transport P
IGI
SceS000002932
ISS
SceS000002932
GO:0006911 phagocytosis, engulfment P
IMP
DmeFBgn0039056
GO:0007010 cytoskeleton organization P
IMP
AthAt5g61980
GO:0007165 signal transduction P
TAS
HsaAPPL1
GO:0007264 small GTPase mediated signal transduction P
IC
SpoSPBC17G9.08c
NAS
SpoSPAC26A3.10
GO:0008283 cell proliferation P
IDA
HsaAPPL1
GO:0008286 insulin receptor signaling pathway P
TAS
HsaAPPL1
GO:0009733 response to auxin stimulus P
IMP
AthAt5g13300
GO:0009965 leaf morphogenesis P
IMP
AthAt5g13300
GO:0010051 xylem and phloem pattern formation P
IMP
AthAt5g13300
GO:0010087 phloem or xylem histogenesis P
IMP
AthAt5g13300
GO:0019915 lipid storage P
IMP
CelWBGene00000565
GO:0043087 regulation of GTPase activity P
ISS
SpoSPAC26A3.10
SPBC17G9.08c
GO:0046324 regulation of glucose import P
IMP
HsaAPPL1
GO:0046685 response to arsenic P
IMP
SpoSPBC17G9.08c
GO:0071276 cellular response to cadmium ion P
IMP
SpoSPBC17G9.08c
GO:0090003 regulation of establishment of protein
localization in plasma membrane		 P
IMP
HsaAPPL1

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2944

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga3160 ENSANGP00000020738
Anopheles gambiae (Aga) aga3161 ENSANGP00000027174
Ashbya gossypii (Ago) ago3918 AFR725C
Drosophila melanogaster (Dme) dme3819 CG30372-PA
(FBgn0050372)
Danio rerio (Dre) dre16048 ENSDARP00000028698
(LOC565798)
Danio rerio (Dre) dre16049 ENSDARP00000037003
Danio rerio (Dre) dre16047 ENSDARP00000050735
Takifugu rubripes (Fru) fru23030 SINFRUP00000134464
Takifugu rubripes (Fru) fru23029 SINFRUP00000136346
Takifugu rubripes (Fru) fru19860 SINFRUP00000142546
Takifugu rubripes (Fru) fru19859 SINFRUP00000142547
Takifugu rubripes (Fru) fru19858 SINFRUP00000142549
Gallus gallus (Gga) gga11581 ENSGALP00000026250
(DDEF1)
Gallus gallus (Gga) gga11582 ENSGALP00000026251
Gallus gallus (Gga) gga11580 ENSGALP00000026252
Gallus gallus (Gga) gga15951 ENSGALP00000026435
Gallus gallus (Gga) gga15952 ENSGALP00000026436
(DDEF2)
Homo sapiens (Hsa) hsa17439 ENSP00000281419
(ASAP2)		 O43150-1
Homo sapiens (Hsa) hsa17440 ENSP00000316404
(ASAP2)		 O43150-2
Homo sapiens (Hsa) hsa30731 ENSP00000344591
(ASAP1)		 C9J570
Homo sapiens (Hsa) hsa30730 ENSP00000350297
(ASAP1)		 B2RNV3
Mus musculus (Mmu) mmu9042 ENSMUSP00000023008
(MGI:1342335)		 Q505F0
Mus musculus (Mmu) mmu9043 ENSMUSP00000080635
Rattus norvegicus (Rno) rno24922 ENSRNOP00000008173
Rattus norvegicus (Rno) rno27142 ENSRNOP00000032092
(RGD:1307379)		 Q1AAU6-2
Rattus norvegicus (Rno) rno24923 ENSRNOP00000036761
Rattus norvegicus (Rno) rno27141 ENSRNOP00000039727
(RGD:1307379)		 Q1AAU6-1
Rattus norvegicus (Rno) rno27140 ENSRNOP00000050699
(RGD:1307379)
Saccharomyces cerevisiae (Sce) sce1591 YDR524C
(S000002932)


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000002932
GO:0005515 protein binding F
IPI
MmuMGI:1342335
GO:0008060 ARF GTPase activator activity F
IDA
SceS000002932
IGI
SceS000002932
ISS
DmeFBgn0050372
SceS000002932
GO:0006888 ER to Golgi vesicle-mediated transport P
IGI
SceS000002932
ISS
SceS000002932
GO:0006891 intra-Golgi vesicle-mediated transport P
IGI
SceS000002932
ISS
SceS000002932
GO:0007264 small GTPase mediated signal transduction P
ISS
DmeFBgn0050372

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC824.09c
(Q9UT34)		 YDR524C
(S000002932)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000002932
SpoSPAC824.09c
GO:0005794 Golgi apparatus C
IDA
SpoSPAC824.09c
GO:0030136 clathrin-coated vesicle C
ISS
SpoSPAC824.09c
GO:0008060 ARF GTPase activator activity F
IDA
SceS000002932
IGI
SceS000002932
ISS
SceS000002932
SpoSPAC824.09c
GO:0006888 ER to Golgi vesicle-mediated transport P
IGI
SceS000002932
ISS
SceS000002932
SpoSPAC824.09c
GO:0006891 intra-Golgi vesicle-mediated transport P
IGI
SceS000002932
ISS
SceS000002932
SpoSPAC824.09c
GO:0051056 regulation of small GTPase mediated signal
transduction		 P
IC
SpoSPAC824.09c

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GO info in one table:

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