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Search term: YEL003W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name GIM4
SGD link S000000729
Alternative ID YEL003W
Description Subunit of the heterohexameric cochaperone prefoldin complex which binds specifically to cytosolic chaperonin and transfers target proteins to it
Synonyms YEL003W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG4098 ACDHYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Molecular chaperone Prefoldin, subunit 2

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At3g22480 GI:15228766
Caenorhabditis elegans (Cel) CE23815
(WBGene00019220)		 GI:17534721 Q9N5M2
Drosophila melanogaster (Dme) 7294772 GI:12230497
Homo sapiens (Hsa) Hs12408675
(PFDN2)		 GI:12408675 Q9UHV9
Saccharomyces cerevisiae (Sce) YEL003w
(S000000729)		 GI:6320834
Schizosaccharomyces pombe (Spo) SPAC227.10 GI:19113876 Q9UTC9


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000000729
GO:0016272 prefoldin complex C
IPI
SceS000000729
ISS
SceS000000729
SpoSPAC227.10
NAS
HsaPFDN2
GO:0005515 protein binding F
IPI
HsaPFDN2
GO:0015631 tubulin binding F
IDA
SceS000000729
GO:0051082 unfolded protein binding F
NAS
HsaPFDN2
GO:0000003 reproduction P
IMP
CelWBGene00019220
GO:0000278 mitotic cell cycle P
RCA
SceS000000729
GO:0002119 nematode larval development P
IMP
CelWBGene00019220
GO:0006457 protein folding P
NAS
HsaPFDN2
GO:0006461 protein complex assembly P
RCA
SceS000000729
GO:0007021 tubulin complex assembly P
IMP
SceS000000729
ISS
SceS000000729
SpoSPAC227.10
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00019220
GO:0010171 body morphogenesis P
IMP
CelWBGene00019220
GO:0035046 pronuclear migration P
IMP
CelWBGene00019220
GO:0040007 growth P
IMP
CelWBGene00019220
GO:0040011 locomotion P
IMP
CelWBGene00019220
GO:0051129 negative regulation of cellular component
organization		 P
RCA
SceS000000729
GO:0051248 negative regulation of protein metabolic
process		 P
RCA
SceS000000729

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
5800

Species Gene ID NCBI link UniProt link
Schizosaccharomyces pombe (Spo) SPAC227.10 GI:19113876 Q9UTC9
Saccharomyces cerevisiae (Sce) GIM4
(S000000729)		 GI:154199604
Eremothecium gossypii (Ego) AGOS_ADL004W GI:45187870
Magnaporthe grisea (Mgr) MGG_01652 GI:145613431
Neurospora crassa (Ncr) NCU09249.1 GI:32422395


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000000729
GO:0016272 prefoldin complex C
IPI
SceS000000729
ISS
SceS000000729
SpoSPAC227.10
GO:0015631 tubulin binding F
IDA
SceS000000729
GO:0000278 mitotic cell cycle P
RCA
SceS000000729
GO:0006461 protein complex assembly P
RCA
SceS000000729
GO:0007021 tubulin complex assembly P
IMP
SceS000000729
ISS
SceS000000729
SpoSPAC227.10
GO:0051129 negative regulation of cellular component
organization		 P
RCA
SceS000000729
GO:0051248 negative regulation of protein metabolic
process		 P
RCA
SceS000000729

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2423

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga1532 ENSANGP00000020462
Ashbya gossypii (Ago) ago1738 ADL004W
Arabidopsis thaliana (Ath) ath14560 At3g22480.1
Arabidopsis thaliana (Ath) ath14561 At3g22480.2
Caenorhabditis elegans (Cel) cel11380 H20J04.5
(CE23815;
WBGene00019220)
Candida glabrata (Cgl) cgl4178 CAGL0L02387g
Cryptococcus neoformans (Cne) cne2229 181.m08248
Dictyostelium discoideum (Ddi) ddi920 DDB0189393
Debaryomyces hansenii (Dha) dha1367 DEHA0B15675g
Drosophila melanogaster (Dme) dme8996 CG6302-PA
(FBgn0010741)
Danio rerio (Dre) dre20937 ENSDARP00000035261
(zgc:136473)		 Q1JPY6
Takifugu rubripes (Fru) fru1505 SINFRUP00000135218
Homo sapiens (Hsa) hsa2453 ENSP00000271485
Kluyveromyces lactis (Kla) kla2681 KLLA0D13904g
Mus musculus (Mmu) mmu1480 ENSMUSP00000006579
(MGI:1276111)		 O70591
Neurospora crassa (Ncr) ncr9015 NCU09249.2
Oryza sativa (Osa) osa50377 5910.m00147
Oryza sativa (Osa) osa65070 6820.m00127
Oryza sativa (Osa) osa72704 7062.m00089
Oryza sativa (Osa) osa72712 7062.m00111
Oryza sativa (Osa) osa74809 7342.m00127
Plasmodium falciparum (Pfa) pfa1530 PF14_0167
Rattus norvegicus (Rno) rno9521 ENSRNOP00000005346
(RGD:1591406)		 B0BN18
Saccharomyces cerevisiae (Sce) sce1620 YEL003W
(S000000729)
Schizosaccharomyces pombe (Spo) spo2068 SPAC227.10 Q9UTC9


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000000729
GO:0005829 cytosol C
TAS
MmuMGI:1276111
GO:0016272 prefoldin complex C
IPI
SceS000000729
ISS
DmeFBgn0010741
SceS000000729
SpoSPAC227.10
GO:0003674 molecular_function F
ND
MmuMGI:1276111
GO:0015631 tubulin binding F
IDA
SceS000000729
GO:0051087 chaperone binding F
ISS
DmeFBgn0010741
GO:0000003 reproduction P
IMP
CelWBGene00019220
GO:0000278 mitotic cell cycle P
RCA
SceS000000729
GO:0002119 nematode larval development P
IMP
CelWBGene00019220
GO:0006457 protein folding P
IDA
MmuMGI:1276111
GO:0006458 'de novo' protein folding P
ISS
DmeFBgn0010741
GO:0006461 protein complex assembly P
RCA
SceS000000729
GO:0006911 phagocytosis, engulfment P
IMP
DmeFBgn0010741
GO:0007021 tubulin complex assembly P
IMP
SceS000000729
ISS
SceS000000729
SpoSPAC227.10
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00019220
GO:0010171 body morphogenesis P
IMP
CelWBGene00019220
GO:0035046 pronuclear migration P
IMP
CelWBGene00019220
GO:0040007 growth P
IMP
CelWBGene00019220
GO:0040011 locomotion P
IMP
CelWBGene00019220
GO:0048477 oogenesis P
IMP
DmeFBgn0010741
GO:0051129 negative regulation of cellular component
organization		 P
RCA
SceS000000729
GO:0051248 negative regulation of protein metabolic
process		 P
RCA
SceS000000729

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC227.10
(Q9UTC9)		 YEL003W
(S000000729)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000000729
GO:0016272 prefoldin complex C
IPI
SceS000000729
ISS
SceS000000729
SpoSPAC227.10
GO:0015631 tubulin binding F
IDA
SceS000000729
GO:0000278 mitotic cell cycle P
RCA
SceS000000729
GO:0006461 protein complex assembly P
RCA
SceS000000729
GO:0007021 tubulin complex assembly P
IMP
SceS000000729
ISS
SceS000000729
SpoSPAC227.10
GO:0051129 negative regulation of cellular component
organization		 P
RCA
SceS000000729
GO:0051248 negative regulation of protein metabolic
process		 P
RCA
SceS000000729

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