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Search term: YEL019C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name MMS21
SGD link S000000745
Alternative ID YEL019C
Description SUMO ligase involved in chromosomal organization and DNA repair; essential subunit of the Mms21-Smc5-Smc6 complex; mutants are sensitive to methyl methanesulfonate and show increased spontaneous mutation and mitotic recombination
Synonyms YEL019C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2979 ACDHYPE

KOGs classification KOGs description
POORLY CHARACTERIZED Protein involved in DNA repair

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At3g15150 GI:15232505
Caenorhabditis elegans (Cel) CE02895
(WBGene00022881)		 GI:17538091 Q23420
Drosophila melanogaster (Dme) 7293085 GI:7293085
Drosophila melanogaster (Dme) 7293089 GI:7293089
Drosophila melanogaster (Dme) 7293090 GI:7293090
Drosophila melanogaster (Dme) 7293977 GI:7293977
Homo sapiens (Hsa) Hs22046831 GI:22046831
Saccharomyces cerevisiae (Sce) YEL019c
(S000000745)		 GI:6320817 P38632
Schizosaccharomyces pombe (Spo) SPAC16A10.06c GI:19114958 Q4PIR3
Encephalitozoon cuniculi (Ecu) ECU09g1300 GI:19173250


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
AthAt3g15150
SceS000000745
SpoSPAC16A10.06c
GO:0005635 nuclear envelope C
IDA
SceS000000745
GO:0005737 cytoplasm C
IDA
SceS000000745
GO:0005829 cytosol C
IDA
SpoSPAC16A10.06c
GO:0030915 Smc5-Smc6 complex C
IDA
SpoSPAC16A10.06c
IPI
SceS000000745
GO:0005515 protein binding F
IPI
SpoSPAC16A10.06c
GO:0019789 SUMO ligase activity F
IDA
AthAt3g15150
SceS000000745
SpoSPAC16A10.06c
IMP
SceS000000745
GO:0000003 reproduction P
IMP
CelWBGene00022881
GO:0000724 double-strand break repair via homologous
recombination		 P
IGI
SpoSPAC16A10.06c
GO:0002119 nematode larval development P
IMP
CelWBGene00022881
GO:0006281 DNA repair P
IMP
SceS000000745
GO:0016925 protein sumoylation P
IDA
SpoSPAC16A10.06c
GO:0032876 negative regulation of DNA endoreduplication P
IMP
AthAt3g15150
GO:0035176 social behavior P
IMP
CelWBGene00022881
GO:0040007 growth P
IMP
CelWBGene00022881
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00022881
GO:0048478 replication fork protection P
IGI
SpoSPAC16A10.06c
GO:0048509 regulation of meristem development P
IMP
AthAt3g15150

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
38892

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) MMS21
(S000000745)		 GI:6320817 P38632
Eremothecium gossypii (Ego) AGOS_AEL053C GI:45190554


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000000745
GO:0005635 nuclear envelope C
IDA
SceS000000745
GO:0005737 cytoplasm C
IDA
SceS000000745
GO:0030915 Smc5-Smc6 complex C
IPI
SceS000000745
GO:0019789 SUMO ligase activity F
IDA
SceS000000745
IMP
SceS000000745
GO:0006281 DNA repair P
IMP
SceS000000745

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_20744

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago2453 AEL053C
Candida glabrata (Cgl) cgl4799 CAGL0M03267g
Debaryomyces hansenii (Dha) dha2247 DEHA0C18458g
Kluyveromyces lactis (Kla) kla495 KLLA0A11462g
Neurospora crassa (Ncr) ncr3855 NCU03968.2
Saccharomyces cerevisiae (Sce) sce1640 YEL019C
(S000000745)


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000000745
GO:0005635 nuclear envelope C
IDA
SceS000000745
GO:0005737 cytoplasm C
IDA
SceS000000745
GO:0030915 Smc5-Smc6 complex C
IPI
SceS000000745
GO:0019789 SUMO ligase activity F
IDA
SceS000000745
IMP
SceS000000745
GO:0006281 DNA repair P
IMP
SceS000000745

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC16A10.06c
(Q4PIR3)		 YEL019C
(S000000745)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000000745
SpoSPAC16A10.06c
GO:0005635 nuclear envelope C
IDA
SceS000000745
GO:0005737 cytoplasm C
IDA
SceS000000745
GO:0005829 cytosol C
IDA
SpoSPAC16A10.06c
GO:0030915 Smc5-Smc6 complex C
IDA
SpoSPAC16A10.06c
IPI
SceS000000745
GO:0005515 protein binding F
IPI
SpoSPAC16A10.06c
GO:0019789 SUMO ligase activity F
IDA
SceS000000745
SpoSPAC16A10.06c
IMP
SceS000000745
GO:0000724 double-strand break repair via homologous
recombination		 P
IGI
SpoSPAC16A10.06c
GO:0006281 DNA repair P
IMP
SceS000000745
GO:0016925 protein sumoylation P
IDA
SpoSPAC16A10.06c
GO:0048478 replication fork protection P
IGI
SpoSPAC16A10.06c

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