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Search term: YEL032W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name MCM3
SGD link S000000758
Alternative ID YEL032W
Description Protein involved in DNA replication; component of the Mcm2-7 hexameric complex that binds chromatin as a part of the pre-replicative complex
Synonyms YEL032W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0479 ACDHYPE

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING DNA replication licensing factor, MCM3 component

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At5g46280 GI:15237411
Caenorhabditis elegans (Cel) CE08392
(WBGene00003155)		 GI:17562700 Q9XVR7
Drosophila melanogaster (Dme) 7290573 GI:4903292
Homo sapiens (Hsa) Hs6631095
(MCM3)		 GI:6631095 P25205
Saccharomyces cerevisiae (Sce) YEL032w
(S000000758)		 GI:6320803 P24279
Schizosaccharomyces pombe (Spo) SPCC1682.02c GI:19075295 P30666
Encephalitozoon cuniculi (Ecu) ECU08g0290 GI:19173355 Q8SRF0
Arabidopsis thaliana (Ath) At5g46280 GI:15237411
Caenorhabditis elegans (Cel) CE08392
(WBGene00003155)		 GI:17562700 Q9XVR7
Drosophila melanogaster (Dme) 7290573 GI:4903292
Homo sapiens (Hsa) Hs6631095
(MCM3)		 GI:6631095 P25205
Saccharomyces cerevisiae (Sce) YEL032w
(S000000758)		 GI:6320803 P24279
Schizosaccharomyces pombe (Spo) SPCC1682.02c GI:19075295 P30666
Encephalitozoon cuniculi (Ecu) ECU08g0290 GI:19173355 Q8SRF0
Arabidopsis thaliana (Ath) At5g46280 GI:15237411
Caenorhabditis elegans (Cel) CE08392
(WBGene00003155)		 GI:17562700 Q9XVR7
Drosophila melanogaster (Dme) 7290573 GI:4903292
Homo sapiens (Hsa) Hs6631095
(MCM3)		 GI:6631095 P25205
Saccharomyces cerevisiae (Sce) YEL032w
(S000000758)		 GI:6320803 P24279
Schizosaccharomyces pombe (Spo) SPCC1682.02c GI:19075295 P30666
Encephalitozoon cuniculi (Ecu) ECU08g0290 GI:19173355 Q8SRF0


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
HsaMCM3
SceS000000758
SpoSPCC1682.02c
GO:0005654 nucleoplasm C
EXP
HsaMCM3
GO:0005656 pre-replicative complex C
IC
SpoSPCC1682.02c
IDA
SceS000000758
GO:0005657 replication fork C
NAS
SpoSPCC1682.02c
GO:0005658 alpha DNA polymerase:primase complex C
TAS
HsaMCM3
GO:0005737 cytoplasm C
IDA
SceS000000758
GO:0005813 centrosome C
IDA
HsaMCM3
GO:0005829 cytosol C
IDA
SpoSPCC1682.02c
GO:0031261 DNA replication preinitiation complex C
IC
SpoSPCC1682.02c
IPI
SceS000000758
GO:0031298 replication fork protection complex C
IDA
SceS000000758
GO:0031390 Ctf18 RFC-like complex C
IC
SpoSPCC1682.02c
GO:0042555 MCM complex C
IDA
SceS000000758
SpoSPCC1682.02c
GO:0003677 DNA binding F
ISS
AthAt5g46280
GO:0003682 chromatin binding F
IDA
SceS000000758
GO:0003688 DNA replication origin binding F
IDA
SceS000000758
GO:0003697 single-stranded DNA binding F
RCA
SceS000000758
GO:0004003 ATP-dependent DNA helicase activity F
RCA
SceS000000758
TAS
SpoSPCC1682.02c
GO:0004386 helicase activity F
RCA
SceS000000758
GO:0005515 protein binding F
IPI
HsaMCM3
GO:0005524 ATP binding F
ISS
AthAt5g46280
GO:0008026 ATP-dependent helicase activity F
RCA
SceS000000758
GO:0008094 DNA-dependent ATPase activity F
ISS
AthAt5g46280
RCA
SceS000000758
GO:0016887 ATPase activity F
IDA
SceS000000758
IMP
SceS000000758
GO:0042623 ATPase activity, coupled F
RCA
SceS000000758
GO:0043138 3'-5' DNA helicase activity F
RCA
SceS000000758
GO:0043140 ATP-dependent 3'-5' DNA helicase
activity		 F
RCA
SceS000000758
GO:0043566 structure-specific DNA binding F
RCA
SceS000000758
GO:0070035 purine NTP-dependent helicase activity F
RCA
SceS000000758
GO:0000003 reproduction P
IMP
CelWBGene00003155
GO:0000084 S phase of mitotic cell cycle P
IC
SpoSPCC1682.02c
IMP
SceS000000758
GO:0000727 double-strand break repair via break-induced
replication		 P
IMP
SceS000000758
GO:0000910 cytokinesis P
IMP
CelWBGene00003155
GO:0006260 DNA replication P
EXP
HsaMCM3
GO:0006267 pre-replicative complex assembly P
IDA
SceS000000758
IPI
SceS000000758
GO:0006268 DNA unwinding involved in replication P
TAS
AthAt5g46280
GO:0006270 DNA-dependent DNA replication initiation P
IDA
SpoSPCC1682.02c
IMP
SceS000000758
ISS
AthAt5g46280
GO:0006271 DNA strand elongation involved in DNA
replication		 P
IMP
SceS000000758
TAS
SpoSPCC1682.02c
GO:0006348 chromatin silencing at telomere P
IMP
SceS000000758
GO:0006461 protein complex assembly P
RCA
SceS000000758
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00003155
GO:0030466 chromatin silencing at silent mating-type
cassette		 P
IMP
SceS000000758
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00003155
GO:0051301 cell division P
IMP
CelWBGene00003155

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
1791

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) MCM3 GI:6631095 P25205
Pan troglodytes (Ptr) MCM3 GI:114607814
Canis familiaris (Cfa) MCM3 GI:73973306
Mus musculus (Mmu) Mcm3
(MGI:101845)		 GI:33859484 P25206
Rattus norvegicus (Rno) Mcm3 GI:109485811
Gallus gallus (Gga) MCM3 GI:57530231
Drosophila melanogaster (Dme) Mcm3
(FBgn0024332)		 GI:24639835
Anopheles gambiae (Aga) AgaP_AGAP001135 GI:58396614
Schizosaccharomyces pombe (Spo) mcm3
(SPCC1682.02c)		 GI:19075295 P30666
Saccharomyces cerevisiae (Sce) MCM3
(S000000758)		 GI:6320803 P24279
Kluyveromyces lactis (Kla) KLLA0E22330g GI:50309887
Eremothecium gossypii (Ego) AGOS_AFR355C GI:45198873
Magnaporthe grisea (Mgr) MGG_01759 GI:145613273
Neurospora crassa (Ncr) NCU08009.1 GI:32416474
Arabidopsis thaliana (Ath) AT5G46280 GI:15237411
Oryza sativa (Osa) Os05g0476200 GI:115464471
Plasmodium falciparum (Pfa) PFE1345c GI:124506457


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
HsaMCM3
MmuMGI:101845
SceS000000758
SpoSPCC1682.02c
GO:0005654 nucleoplasm C
EXP
HsaMCM3
GO:0005656 pre-replicative complex C
IC
SpoSPCC1682.02c
IDA
SceS000000758
ISS
DmeFBgn0024332
NAS
DmeFBgn0024332
GO:0005657 replication fork C
NAS
SpoSPCC1682.02c
GO:0005658 alpha DNA polymerase:primase complex C
TAS
HsaMCM3
GO:0005737 cytoplasm C
IDA
MmuMGI:101845
SceS000000758
GO:0005813 centrosome C
IDA
HsaMCM3
GO:0005829 cytosol C
IDA
SpoSPCC1682.02c
GO:0031261 DNA replication preinitiation complex C
IC
SpoSPCC1682.02c
IPI
SceS000000758
GO:0031298 replication fork protection complex C
IDA
SceS000000758
GO:0031390 Ctf18 RFC-like complex C
IC
SpoSPCC1682.02c
GO:0042555 MCM complex C
IDA
SceS000000758
SpoSPCC1682.02c
GO:0003677 DNA binding F
ISS
AthAt5g46280
GO:0003682 chromatin binding F
IDA
SceS000000758
ISS
DmeFBgn0024332
NAS
DmeFBgn0024332
GO:0003688 DNA replication origin binding F
IDA
SceS000000758
GO:0003697 single-stranded DNA binding F
RCA
SceS000000758
GO:0004003 ATP-dependent DNA helicase activity F
RCA
SceS000000758
TAS
SpoSPCC1682.02c
GO:0004386 helicase activity F
RCA
SceS000000758
GO:0005515 protein binding F
IPI
HsaMCM3
GO:0005524 ATP binding F
ISS
AthAt5g46280
GO:0008026 ATP-dependent helicase activity F
RCA
SceS000000758
GO:0008094 DNA-dependent ATPase activity F
ISS
AthAt5g46280
RCA
SceS000000758
GO:0016887 ATPase activity F
IDA
SceS000000758
IMP
SceS000000758
GO:0042623 ATPase activity, coupled F
RCA
SceS000000758
GO:0043138 3'-5' DNA helicase activity F
IDA
DmeFBgn0024332
RCA
SceS000000758
GO:0043140 ATP-dependent 3'-5' DNA helicase
activity		 F
RCA
SceS000000758
GO:0043566 structure-specific DNA binding F
RCA
SceS000000758
GO:0070035 purine NTP-dependent helicase activity F
RCA
SceS000000758
GO:0000084 S phase of mitotic cell cycle P
IC
SpoSPCC1682.02c
IMP
SceS000000758
GO:0000727 double-strand break repair via break-induced
replication		 P
IMP
SceS000000758
GO:0006260 DNA replication P
EXP
HsaMCM3
GO:0006267 pre-replicative complex assembly P
IDA
SceS000000758
IPI
SceS000000758
ISS
DmeFBgn0024332
NAS
DmeFBgn0024332
GO:0006268 DNA unwinding involved in replication P
TAS
AthAt5g46280
GO:0006270 DNA-dependent DNA replication initiation P
IDA
SpoSPCC1682.02c
IMP
SceS000000758
ISS
AthAt5g46280
GO:0006271 DNA strand elongation involved in DNA
replication		 P
IMP
SceS000000758
TAS
SpoSPCC1682.02c
GO:0006348 chromatin silencing at telomere P
IMP
SceS000000758
GO:0006461 protein complex assembly P
RCA
SceS000000758
GO:0030466 chromatin silencing at silent mating-type
cassette		 P
IMP
SceS000000758

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1729

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga3206 ENSANGP00000012011
Ashbya gossypii (Ago) ago3547 AFR355C
Arabidopsis thaliana (Ath) ath26490 At5g46280.1
Caenorhabditis elegans (Cel) cel2661 C25D7.6
(CE08392;
WBGene00003155)
Candida glabrata (Cgl) cgl4137 CAGL0L01397g
Cryptococcus neoformans (Cne) cne1900 181.m07868
Dictyostelium discoideum (Ddi) ddi5005 DDB0206506
Debaryomyces hansenii (Dha) dha1818 DEHA0C08811g
Drosophila melanogaster (Dme) dme16561 CG4206-PA
(FBgn0024332)
Danio rerio (Dre) dre12727 ENSDARP00000003671
(mcm3)		 Q5RIC5
Danio rerio (Dre) dre29666 ENSDARP00000011412
Encephalitozoon cuniculi (Ecu) ecu186 19173355
Takifugu rubripes (Fru) fru31196 SINFRUP00000160846
Takifugu rubripes (Fru) fru31195 SINFRUP00000167396
Takifugu rubripes (Fru) fru31197 SINFRUP00000168156
Takifugu rubripes (Fru) fru31198 SINFRUP00000175122
Gallus gallus (Gga) gga16232 ENSGALP00000026857
Gallus gallus (Gga) gga16233 ENSGALP00000026858
(MCM3)		 Q5ZMN2
Gallus gallus (Gga) gga16234 ENSGALP00000026859
Gallus gallus (Gga) gga16235 ENSGALP00000026860
Homo sapiens (Hsa) hsa27296 ENSP00000229854
(MCM3)		 P25205
Kluyveromyces lactis (Kla) kla3956 KLLA0E22330g
Mus musculus (Mmu) mmu93 ENSMUSP00000059192
(MGI:101845)		 P25206
Neurospora crassa (Ncr) ncr7801 NCU08009.2
Oryza sativa (Osa) osa76109 7360.m00138
Plasmodium falciparum (Pfa) pfa3719 PFE1345c
Rattus norvegicus (Rno) rno29784 ENSRNOP00000017081
(RGD:1305168)
Saccharomyces cerevisiae (Sce) sce1657 YEL032W
(S000000758)
Schizosaccharomyces pombe (Spo) spo4145 SPCC1682.02c P30666
Yarrowia lipolytica (Yli) yli6269 YALI0F21945g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
MmuMGI:101845
SceS000000758
SpoSPCC1682.02c
GO:0005656 pre-replicative complex C
IC
SpoSPCC1682.02c
IDA
SceS000000758
ISS
DmeFBgn0024332
NAS
DmeFBgn0024332
GO:0005657 replication fork C
NAS
SpoSPCC1682.02c
GO:0005737 cytoplasm C
IDA
MmuMGI:101845
SceS000000758
GO:0005829 cytosol C
IDA
SpoSPCC1682.02c
GO:0031261 DNA replication preinitiation complex C
IC
SpoSPCC1682.02c
IPI
SceS000000758
GO:0031298 replication fork protection complex C
IDA
SceS000000758
GO:0031390 Ctf18 RFC-like complex C
IC
SpoSPCC1682.02c
GO:0042555 MCM complex C
IDA
SceS000000758
SpoSPCC1682.02c
GO:0003677 DNA binding F
ISS
AthAt5g46280
GO:0003682 chromatin binding F
IDA
SceS000000758
ISS
DmeFBgn0024332
NAS
DmeFBgn0024332
GO:0003688 DNA replication origin binding F
IDA
SceS000000758
GO:0003697 single-stranded DNA binding F
RCA
SceS000000758
GO:0004003 ATP-dependent DNA helicase activity F
RCA
SceS000000758
TAS
SpoSPCC1682.02c
GO:0004386 helicase activity F
RCA
SceS000000758
GO:0005524 ATP binding F
ISS
AthAt5g46280
GO:0008026 ATP-dependent helicase activity F
RCA
SceS000000758
GO:0008094 DNA-dependent ATPase activity F
ISS
AthAt5g46280
RCA
SceS000000758
GO:0016887 ATPase activity F
IDA
SceS000000758
IMP
SceS000000758
GO:0042623 ATPase activity, coupled F
RCA
SceS000000758
GO:0043138 3'-5' DNA helicase activity F
IDA
DmeFBgn0024332
RCA
SceS000000758
GO:0043140 ATP-dependent 3'-5' DNA helicase
activity		 F
RCA
SceS000000758
GO:0043566 structure-specific DNA binding F
RCA
SceS000000758
GO:0070035 purine NTP-dependent helicase activity F
RCA
SceS000000758
GO:0000003 reproduction P
IMP
CelWBGene00003155
GO:0000084 S phase of mitotic cell cycle P
IC
SpoSPCC1682.02c
IMP
SceS000000758
GO:0000727 double-strand break repair via break-induced
replication		 P
IMP
SceS000000758
GO:0000910 cytokinesis P
IMP
CelWBGene00003155
GO:0006267 pre-replicative complex assembly P
IDA
SceS000000758
IPI
SceS000000758
ISS
DmeFBgn0024332
NAS
DmeFBgn0024332
GO:0006268 DNA unwinding involved in replication P
TAS
AthAt5g46280
GO:0006270 DNA-dependent DNA replication initiation P
IDA
SpoSPCC1682.02c
IMP
SceS000000758
ISS
AthAt5g46280
GO:0006271 DNA strand elongation involved in DNA
replication		 P
IMP
SceS000000758
TAS
SpoSPCC1682.02c
GO:0006348 chromatin silencing at telomere P
IMP
SceS000000758
GO:0006461 protein complex assembly P
RCA
SceS000000758
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00003155
GO:0030466 chromatin silencing at silent mating-type
cassette		 P
IMP
SceS000000758
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00003155
GO:0051301 cell division P
IMP
CelWBGene00003155

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPCC1682.02c
(P30666)		 YEL032W
(S000000758)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000000758
SpoSPCC1682.02c
GO:0005656 pre-replicative complex C
IC
SpoSPCC1682.02c
IDA
SceS000000758
GO:0005657 replication fork C
NAS
SpoSPCC1682.02c
GO:0005737 cytoplasm C
IDA
SceS000000758
GO:0005829 cytosol C
IDA
SpoSPCC1682.02c
GO:0031261 DNA replication preinitiation complex C
IC
SpoSPCC1682.02c
IPI
SceS000000758
GO:0031298 replication fork protection complex C
IDA
SceS000000758
GO:0031390 Ctf18 RFC-like complex C
IC
SpoSPCC1682.02c
GO:0042555 MCM complex C
IDA
SceS000000758
SpoSPCC1682.02c
GO:0003682 chromatin binding F
IDA
SceS000000758
GO:0003688 DNA replication origin binding F
IDA
SceS000000758
GO:0003697 single-stranded DNA binding F
RCA
SceS000000758
GO:0004003 ATP-dependent DNA helicase activity F
RCA
SceS000000758
TAS
SpoSPCC1682.02c
GO:0004386 helicase activity F
RCA
SceS000000758
GO:0008026 ATP-dependent helicase activity F
RCA
SceS000000758
GO:0008094 DNA-dependent ATPase activity F
RCA
SceS000000758
GO:0016887 ATPase activity F
IDA
SceS000000758
IMP
SceS000000758
GO:0042623 ATPase activity, coupled F
RCA
SceS000000758
GO:0043138 3'-5' DNA helicase activity F
RCA
SceS000000758
GO:0043140 ATP-dependent 3'-5' DNA helicase
activity		 F
RCA
SceS000000758
GO:0043566 structure-specific DNA binding F
RCA
SceS000000758
GO:0070035 purine NTP-dependent helicase activity F
RCA
SceS000000758
GO:0000084 S phase of mitotic cell cycle P
IC
SpoSPCC1682.02c
IMP
SceS000000758
GO:0000727 double-strand break repair via break-induced
replication		 P
IMP
SceS000000758
GO:0006267 pre-replicative complex assembly P
IDA
SceS000000758
IPI
SceS000000758
GO:0006270 DNA-dependent DNA replication initiation P
IDA
SpoSPCC1682.02c
IMP
SceS000000758
GO:0006271 DNA strand elongation involved in DNA
replication		 P
IMP
SceS000000758
TAS
SpoSPCC1682.02c
GO:0006348 chromatin silencing at telomere P
IMP
SceS000000758
GO:0006461 protein complex assembly P
RCA
SceS000000758
GO:0030466 chromatin silencing at silent mating-type
cassette		 P
IMP
SceS000000758

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Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:

s.khadayate@ucl.ac.uk