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Search term: YEL060C


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name PRB1
SGD link S000000786
Alternative ID YEL060C
Description Vacuolar proteinase B (yscB), a serine protease of the subtilisin family; involved in protein degradation in the vacuole and required for full protein degradation during sporulation
Synonyms YEL060C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1153 ----YPE

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Subtilisin-related protease/Vacuolar protease B

Species KOG link NCBI link UniProt link
Saccharomyces cerevisiae (Sce) YCR045c
(S000000641)
GI:6319893 P25381
Saccharomyces cerevisiae (Sce) YEL060c
(S000000786)
GI:6320775 P09232
Saccharomyces cerevisiae (Sce) YOR003w
(S000005529)
GI:6324576 P25036
Schizosaccharomyces pombe (Spo) SPAC1006.01 GI:19115760 Q9UTS0
Schizosaccharomyces pombe (Spo) SPAC4A8.04 GI:19114727 P40903
Encephalitozoon cuniculi (Ecu) ECU01g1130 GI:19075126
Encephalitozoon cuniculi (Ecu) ECU03g1180 GI:19173076 Q8SS86
Saccharomyces cerevisiae (Sce) YCR045c
(S000000641)
GI:6319893 P25381
Saccharomyces cerevisiae (Sce) YEL060c
(S000000786)
GI:6320775 P09232
Saccharomyces cerevisiae (Sce) YOR003w
(S000005529)
GI:6324576 P25036
Schizosaccharomyces pombe (Spo) SPAC1006.01 GI:19115760 Q9UTS0
Schizosaccharomyces pombe (Spo) SPAC4A8.04 GI:19114727 P40903
Encephalitozoon cuniculi (Ecu) ECU01g1130 GI:19075126
Encephalitozoon cuniculi (Ecu) ECU03g1180 GI:19173076 Q8SS86


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000324 fungal-type vacuole C
TAS
SceS000000786
SpoSPAC4A8.04
GO:0000328 fungal-type vacuole lumen C
ISS
SpoSPAC1006.01
TAS
SceS000000786
GO:0005575 cellular_component C
ND
SceS000005529
GO:0005619 ascospore wall C
IDA
SceS000000641
GO:0005635 nuclear envelope C
IDA
SceS000000641
GO:0005794 Golgi apparatus C
IDA
SpoSPAC4A8.04
GO:0004252 serine-type endopeptidase activity F
IMP
SceS000000786
ISA
SceS000000786
ISS
SpoSPAC1006.01
GO:0008233 peptidase activity F
ISS
SceS000005529
GO:0008236 serine-type peptidase activity F
ISS
SceS000000641
SpoSPAC4A8.04
GO:0000747 conjugation with cellular fusion P
IMP
SpoSPAC4A8.04
GO:0006401 RNA catabolic process P
IGI
SpoSPAC4A8.04
GO:0006508 proteolysis P
RCA
SceS000000786
GO:0006914 autophagy P
IMP
SpoSPAC4A8.04
RCA
SceS000000786
GO:0006995 cellular response to nitrogen starvation P
IEP
SpoSPAC4A8.04
IMP
SpoSPAC4A8.04
GO:0007033 vacuole organization P
IMP
SpoSPAC4A8.04
GO:0007039 vacuolar protein catabolic process P
IMP
SceS000000786
ISS
SpoSPAC1006.01
RCA
SceS000000786
GO:0009267 cellular response to starvation P
IMP
SceS000000786
GO:0009415 response to water P
RCA
SceS000000786
GO:0030163 protein catabolic process P
ISS
SceS000005529
GO:0030435 sporulation resulting in formation of a cellular
spore
P
IMP
SceS000000786
RCA
SceS000000786
GO:0030476 ascospore wall assembly P
IMP
SceS000000641
GO:0042594 response to starvation P
RCA
SceS000000786
GO:0051171 regulation of nitrogen compound metabolic
process
P
IMP
SpoSPAC4A8.04
GO:0051603 proteolysis involved in cellular protein catabolic
process
P
IMP
SpoSPAC4A8.04

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
5778

Species Gene ID NCBI link UniProt link
Schizosaccharomyces pombe (Spo) isp6
(SPAC4A8.04)
GI:19114727 P40903
Saccharomyces cerevisiae (Sce) PRB1
(S000000786)
GI:6320775 P09232
Kluyveromyces lactis (Kla) KLLA0D00979g GI:50306283
Eremothecium gossypii (Ego) AGOS_ACR012C GI:45185699
Magnaporthe grisea (Mgr) MGG_03670 GI:39943180
Neurospora crassa (Ncr) NCU00673.1 GI:32408745


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000324 fungal-type vacuole C
TAS
SceS000000786
SpoSPAC4A8.04
GO:0000328 fungal-type vacuole lumen C
TAS
SceS000000786
GO:0005794 Golgi apparatus C
IDA
SpoSPAC4A8.04
GO:0004252 serine-type endopeptidase activity F
IMP
SceS000000786
ISA
SceS000000786
GO:0008236 serine-type peptidase activity F
ISS
SpoSPAC4A8.04
GO:0000747 conjugation with cellular fusion P
IMP
SpoSPAC4A8.04
GO:0006401 RNA catabolic process P
IGI
SpoSPAC4A8.04
GO:0006508 proteolysis P
RCA
SceS000000786
GO:0006914 autophagy P
IMP
SpoSPAC4A8.04
RCA
SceS000000786
GO:0006995 cellular response to nitrogen starvation P
IEP
SpoSPAC4A8.04
IMP
SpoSPAC4A8.04
GO:0007033 vacuole organization P
IMP
SpoSPAC4A8.04
GO:0007039 vacuolar protein catabolic process P
IMP
SceS000000786
RCA
SceS000000786
GO:0009267 cellular response to starvation P
IMP
SceS000000786
GO:0009415 response to water P
RCA
SceS000000786
GO:0030435 sporulation resulting in formation of a cellular
spore
P
IMP
SceS000000786
RCA
SceS000000786
GO:0042594 response to starvation P
RCA
SceS000000786
GO:0051171 regulation of nitrogen compound metabolic
process
P
IMP
SpoSPAC4A8.04
GO:0051603 proteolysis involved in cellular protein catabolic
process
P
IMP
SpoSPAC4A8.04

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2215

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Ashbya gossypii (Ago) ago1060 ACR012C
Candida glabrata (Cgl) cgl363 CAGL0B03619g
Candida glabrata (Cgl) cgl4654 CAGL0L13266g
Cryptococcus neoformans (Cne) cne3826 185.m02407
Debaryomyces hansenii (Dha) dha2089 DEHA0C14916g
Debaryomyces hansenii (Dha) dha2453 DEHA0D03520g
Danio rerio (Dre) dre21217 ENSDARP00000046949
Encephalitozoon cuniculi (Ecu) ecu1763 19075126
Encephalitozoon cuniculi (Ecu) ecu483 19173076
Takifugu rubripes (Fru) fru5529 SINFRUP00000161684
Takifugu rubripes (Fru) fru5530 SINFRUP00000161685
Gallus gallus (Gga) gga25433 ENSGALP00000011501
Homo sapiens (Hsa) hsa1236 ENSP00000303208
(PCSK9)
Q8NBP7-1
Kluyveromyces lactis (Kla) kla2113 KLLA0D00979g
Mus musculus (Mmu) mmu18533 ENSMUSP00000055757
(MGI:2140260)
Q80W65
Neurospora crassa (Ncr) ncr653 NCU00673.2
Neurospora crassa (Ncr) ncr6967 NCU07159.2
Oryza sativa (Osa) osa21051 3638.m00176
Rattus norvegicus (Rno) rno23557 ENSRNOP00000008536
(RGD:728909)
P59996
Saccharomyces cerevisiae (Sce) sce1689 YEL060C
(S000000786)
Saccharomyces cerevisiae (Sce) sce5731 YOR003W
(S000005529)
Schizosaccharomyces pombe (Spo) spo3153 SPAC1006.01 Q9UTS0
Schizosaccharomyces pombe (Spo) spo4069 SPAC4A8.04 P40903
Yarrowia lipolytica (Yli) yli210 YALI0A06435g
Yarrowia lipolytica (Yli) yli1431 YALI0B16500g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000324 fungal-type vacuole C
TAS
SceS000000786
SpoSPAC4A8.04
GO:0000328 fungal-type vacuole lumen C
ISS
SpoSPAC1006.01
TAS
SceS000000786
GO:0005575 cellular_component C
ND
SceS000005529
GO:0005576 extracellular region C
IDA
MmuMGI:2140260
GO:0005615 extracellular space C
IDA
MmuMGI:2140260
ISO
MmuMGI:2140260
GO:0005791 rough endoplasmic reticulum C
ISO
MmuMGI:2140260
GO:0005794 Golgi apparatus C
IDA
SpoSPAC4A8.04
GO:0004252 serine-type endopeptidase activity F
IMP
SceS000000786
ISA
SceS000000786
ISS
MmuMGI:2140260
SpoSPAC1006.01
GO:0008233 peptidase activity F
ISS
SceS000005529
GO:0008236 serine-type peptidase activity F
ISS
SpoSPAC4A8.04
GO:0050750 low-density lipoprotein receptor
binding
F
IDA
MmuMGI:2140260
GO:0000747 conjugation with cellular fusion P
IMP
SpoSPAC4A8.04
GO:0001822 kidney development P
IEP
MmuMGI:2140260
GO:0001889 liver development P
IEP
MmuMGI:2140260
GO:0006401 RNA catabolic process P
IGI
SpoSPAC4A8.04
GO:0006508 proteolysis P
RCA
SceS000000786
GO:0006641 triglyceride metabolic process P
IDA
MmuMGI:2140260
GO:0006644 phospholipid metabolic process P
IDA
MmuMGI:2140260
GO:0006914 autophagy P
IMP
SpoSPAC4A8.04
RCA
SceS000000786
GO:0006917 induction of apoptosis P
ISO
MmuMGI:2140260
GO:0006995 cellular response to nitrogen starvation P
IEP
SpoSPAC4A8.04
IMP
SpoSPAC4A8.04
GO:0007033 vacuole organization P
IMP
SpoSPAC4A8.04
GO:0007039 vacuolar protein catabolic process P
IMP
SceS000000786
ISS
SpoSPAC1006.01
RCA
SceS000000786
GO:0008203 cholesterol metabolic process P
IDA
MmuMGI:2140260
GO:0009267 cellular response to starvation P
IDA
MmuMGI:2140260
IMP
SceS000000786
ISO
MmuMGI:2140260
GO:0009415 response to water P
RCA
SceS000000786
GO:0016540 protein autoprocessing P
ISO
MmuMGI:2140260
ISS
MmuMGI:2140260
GO:0022008 neurogenesis P
IEP
MmuMGI:2140260
GO:0030163 protein catabolic process P
ISS
SceS000005529
GO:0030182 neuron differentiation P
IDA
MmuMGI:2140260
IMP
MmuMGI:2140260
GO:0030435 sporulation resulting in formation of a cellular
spore
P
IMP
SceS000000786
RCA
SceS000000786
GO:0032799 low-density lipoprotein receptor metabolic
process
P
IDA
MmuMGI:2140260
GO:0032802 low-density lipoprotein receptor catabolic
process
P
ISS
MmuMGI:2140260
GO:0032803 regulation of low-density lipoprotein receptor
catabolic process
P
IMP
MmuMGI:2140260
GO:0032869 cellular response to insulin stimulus P
IDA
MmuMGI:2140260
ISO
MmuMGI:2140260
GO:0042157 lipoprotein metabolic process P
IDA
MmuMGI:2140260
GO:0042594 response to starvation P
RCA
SceS000000786
GO:0042632 cholesterol homeostasis P
ISS
MmuMGI:2140260
GO:0043525 positive regulation of neuron apoptosis P
ISO
MmuMGI:2140260
ISS
MmuMGI:2140260
GO:0051171 regulation of nitrogen compound metabolic
process
P
IMP
SpoSPAC4A8.04
GO:0051603 proteolysis involved in cellular protein catabolic
process
P
IMP
SpoSPAC4A8.04
GO:0051605 protein maturation by peptide bond
cleavage
P
ISO
MmuMGI:2140260

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPAC1006.01
(Q9UTS0)
YEL060C
(S000000786)
SPAC4A8.04
(P40903)
YEL060C
(S000000786)