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Search term: YER012W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name PRE1
SGD link S000000814
Alternative ID YER012W
Description Beta 4 subunit of the 20S proteasome; localizes to the nucleus throughout the cell cycle
Synonyms YER012W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0177 ACDHYPE

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING 20S proteasome, regulatory subunit beta type PSMB2/PRE1

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At3g22630 GI:15228805
Arabidopsis thaliana (Ath) At4g14800 GI:15233580
Caenorhabditis elegans (Cel) CE13818
(WBGene00003950)		 GI:17508497 P91477
Drosophila melanogaster (Dme) 7295930 GI:7295930
Drosophila melanogaster (Dme) 7295932 GI:18447102
Drosophila melanogaster (Dme) 7298330
(FBgn0032596)		 GI:20129563
Homo sapiens (Hsa) Hs4506195
(PSMB2)		 GI:4506195 P49721
Saccharomyces cerevisiae (Sce) YER012w
(S000000814)		 GI:6320849 P22141
Schizosaccharomyces pombe (Spo) SPAC31A2.04c GI:19113828 Q09720
Encephalitozoon cuniculi (Ecu) ECU08g0280 GI:19173354 Q8SRF1
Arabidopsis thaliana (Ath) At3g22630 GI:15228805
Arabidopsis thaliana (Ath) At4g14800 GI:15233580
Caenorhabditis elegans (Cel) CE13818
(WBGene00003950)		 GI:17508497 P91477
Drosophila melanogaster (Dme) 7295930 GI:7295930
Drosophila melanogaster (Dme) 7295932 GI:18447102
Drosophila melanogaster (Dme) 7298330
(FBgn0032596)		 GI:20129563
Homo sapiens (Hsa) Hs4506195
(PSMB2)		 GI:4506195 P49721
Saccharomyces cerevisiae (Sce) YER012w
(S000000814)		 GI:6320849 P22141
Schizosaccharomyces pombe (Spo) SPAC31A2.04c GI:19113828 Q09720
Encephalitozoon cuniculi (Ecu) ECU08g0280 GI:19173354 Q8SRF1
Arabidopsis thaliana (Ath) At3g22630 GI:15228805
Arabidopsis thaliana (Ath) At4g14800 GI:15233580
Caenorhabditis elegans (Cel) CE13818
(WBGene00003950)		 GI:17508497 P91477
Drosophila melanogaster (Dme) 7295930 GI:7295930
Drosophila melanogaster (Dme) 7295932 GI:18447102
Drosophila melanogaster (Dme) 7298330
(FBgn0032596)		 GI:20129563
Homo sapiens (Hsa) Hs4506195
(PSMB2)		 GI:4506195 P49721
Saccharomyces cerevisiae (Sce) YER012w
(S000000814)		 GI:6320849 P22141
Schizosaccharomyces pombe (Spo) SPAC31A2.04c GI:19113828 Q09720
Encephalitozoon cuniculi (Ecu) ECU08g0280 GI:19173354 Q8SRF1


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000502 proteasome complex C
TAS
HsaPSMB2
GO:0005634 nucleus C
IDA
SceS000000814
SpoSPAC31A2.04c
TAS
SpoSPAC31A2.04c
GO:0005635 nuclear envelope C
IDA
SpoSPAC31A2.04c
GO:0005773 vacuole C
IDA
AthAt4g14800
At3g22630
GO:0005789 endoplasmic reticulum membrane C
IDA
SceS000000814
GO:0005829 cytosol C
IDA
SpoSPAC31A2.04c
GO:0005838 proteasome regulatory particle C
RCA
SceS000000814
GO:0005839 proteasome core complex C
ISS
DmeFBgn0032596
TAS
AthAt4g14800
At3g22630
GO:0005886 plasma membrane C
IDA
AthAt3g22630
GO:0019774 proteasome core complex, beta-subunit
complex		 C
IDA
SceS000000814
ISS
SpoSPAC31A2.04c
GO:0022624 proteasome accessory complex C
RCA
SceS000000814
GO:0031597 cytosolic proteasome complex C
RCA
SceS000000814
GO:0034515 proteasome storage granule C
IC
SceS000000814
RCA
SceS000000814
GO:0048046 apoplast C
IDA
AthAt3g22630
GO:0004175 endopeptidase activity F
ISS
DmeFBgn0032596
SpoSPAC31A2.04c
GO:0008233 peptidase activity F
ISS
AthAt4g14800
At3g22630
GO:0061133 endopeptidase activator activity F
IMP
SceS000000814
GO:0000003 reproduction P
IMP
CelWBGene00003950
GO:0006508 proteolysis P
RCA
SceS000000814
GO:0006511 ubiquitin-dependent protein catabolic
process		 P
TAS
AthAt3g22630
At4g14800
GO:0006974 response to DNA damage stimulus P
IMP
DmeFBgn0032596
GO:0007346 regulation of mitotic cell cycle P
NAS
SpoSPAC31A2.04c
GO:0008340 determination of adult lifespan P
IMP
CelWBGene00003950
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00003950
GO:0009987 cellular process P
IMP
DmeFBgn0032596
GO:0010499 proteasomal ubiquitin-independent protein
catabolic process		 P
IDA
SceS000000814
GO:0030435 sporulation resulting in formation of a cellular
spore		 P
RCA
SceS000000814
GO:0031145 anaphase-promoting complex-dependent proteasomal
ubiquitin-dependent protein catabolic
process		 P
EXP
HsaPSMB2
GO:0043161 proteasomal ubiquitin-dependent protein catabolic
process		 P
IDA
SceS000000814
NAS
SpoSPAC31A2.04c
GO:0046686 response to cadmium ion P
IEP
AthAt4g14800
GO:0051436 negative regulation of ubiquitin-protein ligase
activity involved in mitotic cell
cycle		 P
EXP
HsaPSMB2
GO:0051437 positive regulation of ubiquitin-protein ligase
activity involved in mitotic cell
cycle		 P
EXP
HsaPSMB2

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
2088

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) PSMB2 GI:4506195 P49721
Pan troglodytes (Ptr) PSMB2 GI:114555492
Canis familiaris (Cfa) PSMB2 GI:73977138
Mus musculus (Mmu) Psmb2
(MGI:1347045)		 GI:31981327 Q8BJX0
Rattus norvegicus (Rno) Psmb2
(RGD:61874)		 GI:8394079
Gallus gallus (Gga) PSMB2 GI:118101652
Drosophila melanogaster (Dme) CG17331
(FBgn0032596)		 GI:20129563
Anopheles gambiae (Aga) AgaP_AGAP008837 GI:118791132
Caenorhabditis elegans (Cel) pbs-4
(CE13818;
WBGene00003950)		 GI:17508497 P91477
Schizosaccharomyces pombe (Spo) SPAC31A2.04c GI:19113828 Q09720
Saccharomyces cerevisiae (Sce) PRE1
(S000000814)		 GI:6320849 P22141
Kluyveromyces lactis (Kla) KLLA0B11660g GI:50304199
Eremothecium gossypii (Ego) AGOS_AAR019W GI:45184842
Magnaporthe grisea (Mgr) MGG_07031 GI:145612303
Neurospora crassa (Ncr) NCU01368.1 GI:32412762
Arabidopsis thaliana (Ath) PBD2 GI:15233580
Arabidopsis thaliana (Ath) PBD1 GI:15228805
Oryza sativa (Osa) Os03g0695600 GI:115454751
Plasmodium falciparum (Pfa) PF14_0676 GI:124810342


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000502 proteasome complex C
TAS
HsaPSMB2
GO:0005575 cellular_component C
ND
MmuMGI:1347045
GO:0005634 nucleus C
IDA
SceS000000814
SpoSPAC31A2.04c
TAS
SpoSPAC31A2.04c
GO:0005635 nuclear envelope C
IDA
SpoSPAC31A2.04c
GO:0005773 vacuole C
IDA
AthPBD2
PBD1
GO:0005789 endoplasmic reticulum membrane C
IDA
SceS000000814
GO:0005829 cytosol C
IDA
SpoSPAC31A2.04c
GO:0005838 proteasome regulatory particle C
RCA
SceS000000814
GO:0005839 proteasome core complex C
ISS
DmeFBgn0032596
TAS
AthPBD2
PBD1
GO:0005886 plasma membrane C
IDA
AthPBD1
GO:0019774 proteasome core complex, beta-subunit
complex		 C
IDA
SceS000000814
ISS
SpoSPAC31A2.04c
GO:0022624 proteasome accessory complex C
RCA
SceS000000814
GO:0031597 cytosolic proteasome complex C
RCA
SceS000000814
GO:0034515 proteasome storage granule C
IC
SceS000000814
RCA
SceS000000814
GO:0048046 apoplast C
IDA
AthPBD1
GO:0003674 molecular_function F
ND
MmuMGI:1347045
GO:0004175 endopeptidase activity F
ISS
DmeFBgn0032596
SpoSPAC31A2.04c
GO:0008233 peptidase activity F
ISS
AthPBD2
PBD1
GO:0061133 endopeptidase activator activity F
IMP
SceS000000814
GO:0000003 reproduction P
IMP
CelWBGene00003950
GO:0006508 proteolysis P
RCA
SceS000000814
GO:0006511 ubiquitin-dependent protein catabolic
process		 P
TAS
AthPBD2
PBD1
GO:0006974 response to DNA damage stimulus P
IMP
DmeFBgn0032596
GO:0007346 regulation of mitotic cell cycle P
NAS
SpoSPAC31A2.04c
GO:0008150 biological_process P
ND
MmuMGI:1347045
GO:0008340 determination of adult lifespan P
IMP
CelWBGene00003950
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00003950
GO:0009987 cellular process P
IMP
DmeFBgn0032596
GO:0010499 proteasomal ubiquitin-independent protein
catabolic process		 P
IDA
SceS000000814
GO:0030435 sporulation resulting in formation of a cellular
spore		 P
RCA
SceS000000814
GO:0031145 anaphase-promoting complex-dependent proteasomal
ubiquitin-dependent protein catabolic
process		 P
EXP
HsaPSMB2
GO:0043161 proteasomal ubiquitin-dependent protein catabolic
process		 P
IDA
SceS000000814
NAS
SpoSPAC31A2.04c
GO:0046686 response to cadmium ion P
IEP
AthPBD2
GO:0051436 negative regulation of ubiquitin-protein ligase
activity involved in mitotic cell
cycle		 P
EXP
HsaPSMB2
GO:0051437 positive regulation of ubiquitin-protein ligase
activity involved in mitotic cell
cycle		 P
EXP
HsaPSMB2

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2312

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga10891 ENSANGP00000016798
Ashbya gossypii (Ago) ago205 AAR019W
Arabidopsis thaliana (Ath) ath14575 At3g22630.1
Arabidopsis thaliana (Ath) ath19275 At4g14800.1
Caenorhabditis elegans (Cel) cel15825 T20F5.2
(CE13818;
WBGene00003950)
Candida glabrata (Cgl) cgl2481 CAGL0H09548g
Cryptococcus neoformans (Cne) cne5567 179.m00427
Dictyostelium discoideum (Ddi) ddi236 DDB0190287
Debaryomyces hansenii (Dha) dha2979 DEHA0D15180g
Drosophila melanogaster (Dme) dme2664 CG17331-PA
(FBgn0032596)
Danio rerio (Dre) dre16478 ENSDARP00000041113
(psmb2)		 Q6DHI9
Encephalitozoon cuniculi (Ecu) ecu185 19173354
Takifugu rubripes (Fru) fru13268 SINFRUP00000152343
Gallus gallus (Gga) gga12940 ENSGALP00000003732
(PSMB2)
Homo sapiens (Hsa) hsa835 ENSP00000246311
Kluyveromyces lactis (Kla) kla1047 KLLA0B11660g
Mus musculus (Mmu) mmu18903 ENSMUSP00000030642
(MGI:1347045)		 Q9R1P3
Neurospora crassa (Ncr) ncr1327 NCU01368.2
Oryza sativa (Osa) osa54109 6302.m00160
Plasmodium falciparum (Pfa) pfa1503 PF14_0676
Rattus norvegicus (Rno) rno23944 ENSRNOP00000015618
(RGD:61874)		 P40307
Saccharomyces cerevisiae (Sce) sce1723 YER012W
(S000000814)
Schizosaccharomyces pombe (Spo) spo1625 SPAC31A2.04c Q09720
Yarrowia lipolytica (Yli) yli1206 YALI0B11374g