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Search term: YER025W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name GCD11
SGD link S000000827
Alternative ID YER025W
Description Gamma subunit of the translation initiation factor eIF2, involved in the identification of the start codon; binds GTP when forming the ternary complex with GTP and tRNAi-Met
Synonyms YER025W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0466 ACDHYPE

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING Translation initiation factor 2, gamma subunit (eIF-2gamma; GTPase)

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g04170 GI:15219669
Arabidopsis thaliana (Ath) At2g18720 GI:15224215
Arabidopsis thaliana (Ath) At4g18330 GI:7428968
Caenorhabditis elegans (Cel) CE27254
(WBGene00021466)		 GI:17509919 Q95XR0
Drosophila melanogaster (Dme) 7299981 GI:2494300
Homo sapiens (Hsa) Hs22057930 GI:22057930
Homo sapiens (Hsa) Hs4503507
(EIF2S3)		 GI:4503507 P41091
Saccharomyces cerevisiae (Sce) YER025w
(S000000827)		 GI:6320863 P32481
Schizosaccharomyces pombe (Spo) SPBC17G9.09 GI:19112690 Q09130
Encephalitozoon cuniculi (Ecu) ECU01g0700 GI:19075080
Arabidopsis thaliana (Ath) At1g04170 GI:15219669
Arabidopsis thaliana (Ath) At2g18720 GI:15224215
Arabidopsis thaliana (Ath) At4g18330 GI:7428968
Caenorhabditis elegans (Cel) CE27254
(WBGene00021466)		 GI:17509919 Q95XR0
Drosophila melanogaster (Dme) 7299981 GI:2494300
Homo sapiens (Hsa) Hs22057930 GI:22057930
Homo sapiens (Hsa) Hs4503507
(EIF2S3)		 GI:4503507 P41091
Saccharomyces cerevisiae (Sce) YER025w
(S000000827)		 GI:6320863 P32481
Schizosaccharomyces pombe (Spo) SPBC17G9.09 GI:19112690 Q09130
Encephalitozoon cuniculi (Ecu) ECU01g0700 GI:19075080
Arabidopsis thaliana (Ath) At1g04170 GI:15219669
Arabidopsis thaliana (Ath) At2g18720 GI:15224215
Arabidopsis thaliana (Ath) At4g18330 GI:7428968
Caenorhabditis elegans (Cel) CE27254
(WBGene00021466)		 GI:17509919 Q95XR0
Drosophila melanogaster (Dme) 7299981 GI:2494300
Homo sapiens (Hsa) Hs22057930 GI:22057930
Homo sapiens (Hsa) Hs4503507
(EIF2S3)		 GI:4503507 P41091
Saccharomyces cerevisiae (Sce) YER025w
(S000000827)		 GI:6320863 P32481
Schizosaccharomyces pombe (Spo) SPBC17G9.09 GI:19112690 Q09130
Encephalitozoon cuniculi (Ecu) ECU01g0700 GI:19075080


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SpoSPBC17G9.09
GO:0005829 cytosol C
EXP
HsaEIF2S3
IDA
SpoSPBC17G9.09
GO:0005840 ribosome C
TAS
SceS000000827
GO:0005850 eukaryotic translation initiation factor 2
complex		 C
IMP
SceS000000827
ISS
SceS000000827
GO:0043614 multi-eIF complex C
IDA
SceS000000827
GO:0000049 tRNA binding F
IMP
SceS000000827
GO:0003743 translation initiation factor activity F
IDA
HsaEIF2S3
ISS
AthAt4g18330
At1g04170
TAS
SceS000000827
GO:0005515 protein binding F
IPI
HsaEIF2S3
GO:0005525 GTP binding F
IMP
SceS000000827
GO:0008135 translation factor activity, nucleic acid
binding		 F
IDA
HsaEIF2S3
ISS
AthAt1g04170
At2g18720
GO:0000003 reproduction P
IMP
CelWBGene00021466
GO:0002119 nematode larval development P
IMP
CelWBGene00021466
GO:0006413 translational initiation P
IDA
HsaEIF2S3
ISS
AthAt4g18330
GO:0006417 regulation of translation P
RCA
SceS000000827
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00021466
GO:0010171 body morphogenesis P
IMP
CelWBGene00021466
GO:0040007 growth P
IMP
CelWBGene00021466
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00021466
GO:0040011 locomotion P
IMP
CelWBGene00021466
GO:0040018 positive regulation of multicellular organism
growth		 P
IMP
CelWBGene00021466
GO:0045903 positive regulation of translational
fidelity		 P
IMP
SceS000000827

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
99414

Species Gene ID NCBI link UniProt link
Mus musculus (Mmu) Eif2s3y
(MGI:1349430)		 GI:7242148 Q9D791
Caenorhabditis elegans (Cel) Y39G10AR.8
(CE27254;
WBGene00021466)		 GI:17509919 Q95XR0
Schizosaccharomyces pombe (Spo) tif213
(SPBC17G9.09)		 GI:19112690 Q09130
Saccharomyces cerevisiae (Sce) GCD11
(S000000827)		 GI:6320863 P32481
Kluyveromyces lactis (Kla) KLLA0D10571g GI:50307107
Eremothecium gossypii (Ego) AGOS_ABR175W GI:45185406
Magnaporthe grisea (Mgr) MGG_01592 GI:145613496
Neurospora crassa (Ncr) NCU02810.1 GI:32419040
Arabidopsis thaliana (Ath) AT4G18330 GI:42572941
Arabidopsis thaliana (Ath) AT2G18720 GI:186501375


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SpoSPBC17G9.09
GO:0005829 cytosol C
IDA
SpoSPBC17G9.09
GO:0005840 ribosome C
TAS
SceS000000827
GO:0005850 eukaryotic translation initiation factor 2
complex		 C
IMP
SceS000000827
ISS
SceS000000827
GO:0043614 multi-eIF complex C
IDA
SceS000000827
GO:0000049 tRNA binding F
IMP
SceS000000827
GO:0003743 translation initiation factor activity F
ISS
AthAt4g18330
TAS
SceS000000827
GO:0005525 GTP binding F
IMP
SceS000000827
GO:0008135 translation factor activity, nucleic acid
binding		 F
ISS
AthAt2g18720
GO:0000003 reproduction P
IMP
CelWBGene00021466
GO:0002119 nematode larval development P
IMP
CelWBGene00021466
GO:0006413 translational initiation P
ISS
AthAt4g18330
GO:0006417 regulation of translation P
RCA
SceS000000827
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00021466
GO:0010171 body morphogenesis P
IMP
CelWBGene00021466
GO:0040007 growth P
IMP
CelWBGene00021466
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00021466
GO:0040011 locomotion P
IMP
CelWBGene00021466
GO:0040018 positive regulation of multicellular organism
growth		 P
IMP
CelWBGene00021466
GO:0045903 positive regulation of translational
fidelity		 P
IMP
SceS000000827

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1354

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga6048 ENSANGP00000011873
Ashbya gossypii (Ago) ago768 ABR175W
Arabidopsis thaliana (Ath) ath361 At1g04170.1
Arabidopsis thaliana (Ath) ath8728 At2g18720.1
Arabidopsis thaliana (Ath) ath19703 At4g18330.2
Caenorhabditis elegans (Cel) cel18599 Y39G10AR.8
(CE27254;
WBGene00021466)
Candida glabrata (Cgl) cgl2881 CAGL0I08327g
Cryptococcus neoformans (Cne) cne678 163.m03861
Dictyostelium discoideum (Ddi) ddi12704 DDB0215353
Debaryomyces hansenii (Dha) dha3712 DEHA0E10648g
Drosophila melanogaster (Dme) dme12706 CG6476-PB
(FBgn0003600)
Drosophila melanogaster (Dme) dme12707 CG6476-PC
(FBgn0003600)
Danio rerio (Dre) dre16139 ENSDARP00000027695
(eif2s3)		 Q7SXT9
Encephalitozoon cuniculi (Ecu) ecu1717 19075080
Takifugu rubripes (Fru) fru26976 SINFRUP00000135402
Gallus gallus (Gga) gga2325 ENSGALP00000026306
Gallus gallus (Gga) gga2324 ENSGALP00000026307
(EIF2S3)		 Q5ZMS3
Homo sapiens (Hsa) hsa32560 ENSP00000253039
(EIF2S3)		 P41091
Kluyveromyces lactis (Kla) kla2531 KLLA0D10571g
Mus musculus (Mmu) mmu29303 ENSMUSP00000059395
(MGI:1349431)		 Q9Z0N1
Mus musculus (Mmu) mmu30115 ENSMUSP00000071159
Neurospora crassa (Ncr) ncr2720 NCU02810.2
Oryza sativa (Osa) osa1672 1890.m00144
Oryza sativa (Osa) osa69365 7075.m00132
Oryza sativa (Osa) osa75876 7246.m00181
Plasmodium falciparum (Pfa) pfa1396 PF14_0104
Rattus norvegicus (Rno) rno31561 ENSRNOP00000008489
(RGD:1561279)		 P81795
Saccharomyces cerevisiae (Sce) sce1739 YER025W
(S000000827)
Schizosaccharomyces pombe (Spo) spo4852 SPBC17G9.09 Q09130
Yarrowia lipolytica (Yli) yli139 YALI0A03839g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000775 chromosome, centromeric region C
TAS
DmeFBgn0003600
GO:0000792 heterochromatin C
NAS
DmeFBgn0003600
TAS
DmeFBgn0003600
GO:0005575 cellular_component C
ND
MmuMGI:1349431
GO:0005634 nucleus C
NAS
DmeFBgn0003600
GO:0005737 cytoplasm C
IDA
SpoSPBC17G9.09
GO:0005829 cytosol C
IDA
SpoSPBC17G9.09
ISS
DmeFBgn0003600
GO:0005840 ribosome C
TAS
SceS000000827
GO:0005850 eukaryotic translation initiation factor 2
complex		 C
IMP
SceS000000827
ISS
DmeFBgn0003600
PfaPF14_0104
SceS000000827
NAS
DmeFBgn0003600
GO:0043614 multi-eIF complex C
IDA
SceS000000827
GO:0000049 tRNA binding F
IMP
SceS000000827
NAS
DmeFBgn0003600
GO:0003674 molecular_function F
ND
MmuMGI:1349431
GO:0003682 chromatin binding F
NAS
DmeFBgn0003600
GO:0003743 translation initiation factor activity F
ISS
AthAt4g18330
At1g04170
DmeFBgn0003600
TAS
SceS000000827
GO:0005525 GTP binding F
IMP
SceS000000827
NAS
DmeFBgn0003600
GO:0008135 translation factor activity, nucleic acid
binding		 F
ISS
AthAt1g04170
At2g18720
GO:0042054 histone methyltransferase activity F
IDA
DmeFBgn0003600
NAS
DmeFBgn0003600
GO:0046974 histone methyltransferase activity (H3-K9
specific)		 F
IDA
DmeFBgn0003600
NAS
DmeFBgn0003600
TAS
DmeFBgn0003600
GO:0000003 reproduction P
IMP
CelWBGene00021466
GO:0002119 nematode larval development P
IMP
CelWBGene00021466
GO:0006306 DNA methylation P
IMP
DmeFBgn0003600
GO:0006325 chromatin organization P
IMP
DmeFBgn0003600
NAS
DmeFBgn0003600
GO:0006342 chromatin silencing P
IMP
DmeFBgn0003600
GO:0006348 chromatin silencing at telomere P
IMP
DmeFBgn0003600
GO:0006413 translational initiation P
ISS
AthAt4g18330
DmeFBgn0003600
PfaPF14_0104
NAS
DmeFBgn0003600
GO:0006417 regulation of translation P
RCA
SceS000000827
GO:0008150 biological_process P
ND
MmuMGI:1349431
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00021466
GO:0010171 body morphogenesis P
IMP
CelWBGene00021466
GO:0016458 gene silencing P
IMP
DmeFBgn0003600
NAS
DmeFBgn0003600
GO:0016570 histone modification P
IMP
DmeFBgn0003600
GO:0016571 histone methylation P
IDA
DmeFBgn0003600
TAS
DmeFBgn0003600
GO:0030702 chromatin silencing at centromere P
IMP
DmeFBgn0003600
GO:0031507 heterochromatin formation P
IMP
DmeFBgn0003600
GO:0040007 growth P
IMP
CelWBGene00021466
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00021466
GO:0040011 locomotion P
IMP
CelWBGene00021466
GO:0040018 positive regulation of multicellular organism
growth		 P
IMP
CelWBGene00021466
GO:0045903 positive regulation of translational
fidelity		 P
IMP
SceS000000827
GO:0048132 female germ-line stem cell division P
IDA
DmeFBgn0003600
GO:0048477 oogenesis P
IDA
DmeFBgn0003600
IMP
DmeFBgn0003600
GO:0051276 chromosome organization P
IMP
DmeFBgn0003600
GO:0051567 histone H3-K9 methylation P
IDA
DmeFBgn0003600
IMP
DmeFBgn0003600
GO:0070868 heterochromatin organization involved in chromatin
silencing		 P
IMP
DmeFBgn0003600

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC17G9.09
(Q09130)		 YER025W
(S000000827)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SpoSPBC17G9.09
GO:0005829 cytosol C
IDA
SpoSPBC17G9.09
GO:0005840 ribosome C
TAS
SceS000000827
GO:0005850 eukaryotic translation initiation factor 2
complex		 C
IMP
SceS000000827
ISS
SceS000000827
GO:0043614 multi-eIF complex C
IDA
SceS000000827
GO:0000049 tRNA binding F
IMP
SceS000000827
GO:0003743 translation initiation factor activity F
TAS
SceS000000827
GO:0005525 GTP binding F
IMP
SceS000000827
GO:0006417 regulation of translation P
RCA
SceS000000827
GO:0045903 positive regulation of translational
fidelity		 P
IMP
SceS000000827

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