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Search term: YER043C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name SAH1
SGD link S000000845
Alternative ID YER043C
Description S-adenosyl-L-homocysteine hydrolase, catabolizes S-adenosyl-L-homocysteine which is formed after donation of the activated methyl group of S-adenosyl-L-methionine (AdoMet) to an acceptor
Synonyms YER043C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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Query species:

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1370 ACDHYP-

KOGs classification KOGs description
METABOLISM S-adenosylhomocysteine hydrolase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At3g23810 GI:15229522
Arabidopsis thaliana (Ath) At4g13940 GI:15236376
Caenorhabditis elegans (Cel) CE17154
(WBGene00019322)		 GI:17506425 P27604
Drosophila melanogaster (Dme) 7292277 GI:7292277
Drosophila melanogaster (Dme) 7293068 GI:7293068
Drosophila melanogaster (Dme) 7300202 GI:17137138
Homo sapiens (Hsa) Hs17439584 GI:17439584
Homo sapiens (Hsa) Hs17439773 GI:17439773
Homo sapiens (Hsa) Hs18566749 GI:18566749
Homo sapiens (Hsa) Hs20483309 GI:20483309
Homo sapiens (Hsa) Hs20537421 GI:20537421
Homo sapiens (Hsa) Hs21361647 GI:16588687 O43210
Homo sapiens (Hsa) Hs22041394 GI:22041394
Homo sapiens (Hsa) Hs22051990 GI:22051990
Homo sapiens (Hsa) Hs22054319 GI:22054319
Homo sapiens (Hsa) Hs9951915
(AHCY)		 GI:9951915 P23526
Homo sapiens (Hsa) HsM5729724 GI:5729724
Saccharomyces cerevisiae (Sce) YER043c
(S000000845)		 GI:6320882 P39954
Schizosaccharomyces pombe (Spo) SPBC8D2.18c GI:19112372 O13639


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000000845
NAS
HsaAHCY
GO:0005773 vacuole C
IDA
AthAt4g13940
At3g23810
GO:0005829 cytosol C
IDA
SpoSPBC8D2.18c
GO:0005886 plasma membrane C
IDA
AthAt4g13940
At3g23810
GO:0016020 membrane C
IDA
AthAt3g23810
At4g13940
GO:0004013 adenosylhomocysteinase activity F
IMP
AthAt4g13940
ISS
AthAt4g13940
At3g23810
SceS000000845
SpoSPBC8D2.18c
TAS
HsaAHCY
GO:0005507 copper ion binding F
IDA
AthAt4g13940
GO:0005515 protein binding F
IPI
HsaAHCY
GO:0000003 reproduction P
IMP
CelWBGene00019322
GO:0002119 nematode larval development P
IMP
CelWBGene00019322
GO:0006346 methylation-dependent chromatin
silencing		 P
IMP
AthAt4g13940
GO:0006555 methionine metabolic process P
ISS
SpoSPBC8D2.18c
NAS
SceS000000845
GO:0006730 one-carbon metabolic process P
ISS
AthAt3g23810
At4g13940
NAS
HsaAHCY
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00019322
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00019322
GO:0009793 embryo development ending in seed
dormancy		 P
IMP
AthAt4g13940
NAS
AthAt4g13940
GO:0010171 body morphogenesis P
IMP
CelWBGene00019322
GO:0016259 selenocysteine metabolic process P
ISS
SpoSPBC8D2.18c
NAS
SceS000000845
GO:0016441 posttranscriptional gene silencing P
IMP
AthAt4g13940
GO:0032940 secretion by cell P
IMP
CelWBGene00019322
GO:0040007 growth P
IMP
CelWBGene00019322
GO:0040011 locomotion P
IMP
CelWBGene00019322
GO:0040015 negative regulation of multicellular organism
growth		 P
IMP
CelWBGene00019322

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
554

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) AHCY GI:9951915 P23526
Pan troglodytes (Ptr) AHCY GI:114681558
Canis familiaris (Cfa) AHCY GI:73991635
Mus musculus (Mmu) Ahcy
(MGI:87968)		 GI:61098092 A2ALT5
Rattus norvegicus (Rno) Ahcy
(RGD:69260)		 GI:8392878
Gallus gallus (Gga) AHCY GI:118100510
Drosophila melanogaster (Dme) Ahcy13
(FBgn0014455)		 GI:24642172
Anopheles gambiae (Aga) AgaP_AGAP000719 GI:58381447
Caenorhabditis elegans (Cel) K02F2.2
(CE17154;
WBGene00019322)		 GI:17506425 P27604
Schizosaccharomyces pombe (Spo) SPBC8D2.18c GI:19112372 O13639
Saccharomyces cerevisiae (Sce) SAH1
(S000000845)		 GI:6320882 P39954
Kluyveromyces lactis (Kla) KLLA0A01199g GI:50302237
Eremothecium gossypii (Ego) AGOS_AFR243C GI:45198761
Magnaporthe grisea (Mgr) MGG_05155 GI:39940170
Neurospora crassa (Ncr) NCU07930.1 GI:32416316
Arabidopsis thaliana (Ath) SAHH2 GI:15229522
Arabidopsis thaliana (Ath) MEE58 GI:15236376
Oryza sativa (Osa) Os11g0455500 GI:115485403
Plasmodium falciparum (Pfa) PFE1050w GI:124506339


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
ISO
MmuMGI:87968
GO:0005737 cytoplasm C
IDA
SceS000000845
NAS
HsaAHCY
GO:0005773 vacuole C
IDA
AthSAHH2
MEE58
GO:0005829 cytosol C
IDA
MmuMGI:87968
SpoSPBC8D2.18c
ISO
MmuMGI:87968
GO:0005886 plasma membrane C
IDA
AthSAHH2
MEE58
GO:0016020 membrane C
IDA
AthSAHH2
MEE58
GO:0019717 synaptosome C
ISO
MmuMGI:87968
GO:0004013 adenosylhomocysteinase activity F
IDA
MmuMGI:87968
IMP
AthMEE58
ISO
MmuMGI:87968
ISS
AthSAHH2
MEE58
DmeFBgn0014455
SceS000000845
SpoSPBC8D2.18c
NAS
DmeFBgn0014455
TAS
HsaAHCY
GO:0005507 copper ion binding F
IDA
AthMEE58
MmuMGI:87968
GO:0005515 protein binding F
IPI
HsaAHCY
GO:0030554 adenyl nucleotide binding F
ISO
MmuMGI:87968
GO:0042802 identical protein binding F
ISO
MmuMGI:87968
GO:0043621 protein self-association F
IPI
MmuMGI:87968
GO:0051287 NAD or NADH binding F
ISO
MmuMGI:87968
GO:0000003 reproduction P
IMP
CelWBGene00019322
GO:0002119 nematode larval development P
IMP
CelWBGene00019322
GO:0002439 chronic inflammatory response to antigenic
stimulus		 P
ISO
MmuMGI:87968
GO:0006346 methylation-dependent chromatin
silencing		 P
IMP
AthMEE58
GO:0006555 methionine metabolic process P
ISS
SpoSPBC8D2.18c
NAS
SceS000000845
GO:0006730 one-carbon metabolic process P
ISS
AthSAHH2
MEE58
NAS
HsaAHCY
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00019322
GO:0007584 response to nutrient P
ISO
MmuMGI:87968
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00019322
GO:0009793 embryo development ending in seed
dormancy		 P
IMP
AthMEE58
NAS
AthMEE58
GO:0010171 body morphogenesis P
IMP
CelWBGene00019322
GO:0016259 selenocysteine metabolic process P
ISS
SpoSPBC8D2.18c
NAS
SceS000000845
GO:0016441 posttranscriptional gene silencing P
IMP
AthMEE58
GO:0019510 S-adenosylhomocysteine catabolic
process		 P
IDA
MmuMGI:87968
ISO
MmuMGI:87968
GO:0032940 secretion by cell P
IMP
CelWBGene00019322
GO:0040007 growth P
IMP
CelWBGene00019322
GO:0040011 locomotion P
IMP
CelWBGene00019322
GO:0040015 negative regulation of multicellular organism
growth		 P
IMP
CelWBGene00019322
GO:0042745 circadian sleep/wake cycle P
ISO
MmuMGI:87968

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_394

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga15375 ENSANGP00000011950
Anopheles gambiae (Aga) aga15470 ENSANGP00000021319
Ashbya gossypii (Ago) ago3435 AFR243C
Arabidopsis thaliana (Ath) ath14702 At3g23810.1
Arabidopsis thaliana (Ath) ath19161 At4g13940.1
Caenorhabditis elegans (Cel) cel11695 K02F2.2
(CE17154;
WBGene00019322)
Candida glabrata (Cgl) cgl511 CAGL0C02189g
Cryptococcus neoformans (Cne) cne725 163.m03780
Dictyostelium discoideum (Ddi) ddi11415 DDB0191108
Debaryomyces hansenii (Dha) dha6647 DEHA0G21186g
Drosophila melanogaster (Dme) dme17936 CG11654-PA
(FBgn0014455)
Drosophila melanogaster (Dme) dme7650 CG9977-PA
(FBgn0035371)
Danio rerio (Dre) dre20850 ENSDARP00000002844
(ahcy)		 Q803T5
Danio rerio (Dre) dre22697 ENSDARP00000019607
(ahcyl1)		 Q49S42
Takifugu rubripes (Fru) fru6163 SINFRUP00000135355
Takifugu rubripes (Fru) fru1461 SINFRUP00000136848
Takifugu rubripes (Fru) fru9520 SINFRUP00000142030
Takifugu rubripes (Fru) fru9519 SINFRUP00000168889
Gallus gallus (Gga) gga13356 ENSGALP00000000438
(AHCYL1)		 Q5F3Q3
Gallus gallus (Gga) gga11758 ENSGALP00000003151
Gallus gallus (Gga) gga11756 ENSGALP00000003152
(AHCY)
Gallus gallus (Gga) gga11759 ENSGALP00000003153
Gallus gallus (Gga) gga11757 ENSGALP00000003154
Gallus gallus (Gga) gga6835 ENSGALP00000012914
(AHCYL2)
Homo sapiens (Hsa) hsa20067 ENSP00000217426
(AHCY)		 P23526
Homo sapiens (Hsa) hsa1660 ENSP00000310774
Homo sapiens (Hsa) hsa29410 ENSP00000315931
(AHCYL2)		 Q96HN2
Homo sapiens (Hsa) hsa18678 ENSP00000322497
Homo sapiens (Hsa) hsa1661 ENSP00000352092
(AHCYL1)		 O43865-2
Kluyveromyces lactis (Kla) kla49 KLLA0A01199g
Mus musculus (Mmu) mmu21556 ENSMUSP00000003227
Mus musculus (Mmu) mmu17366 ENSMUSP00000029490
(MGI:2385184)		 Q80SW1
Mus musculus (Mmu) mmu10402 ENSMUSP00000052276
Mus musculus (Mmu) mmu15828 ENSMUSP00000061851
(MGI:3642725)		 P50247
Mus musculus (Mmu) mmu21555 ENSMUSP00000067638
(MGI:1921590)
Neurospora crassa (Ncr) ncr7726 NCU07930.2
Oryza sativa (Osa) osa73908 7164.m00152
Oryza sativa (Osa) osa73960 7164.m00188
Plasmodium falciparum (Pfa) pfa3659 PFE1050w
Rattus norvegicus (Rno) rno20074 ENSRNOP00000024310
(RGD:69260)		 P10760
Rattus norvegicus (Rno) rno16823 ENSRNOP00000025152
(RGD:1309768)		 B5DFN2
Rattus norvegicus (Rno) rno20961 ENSRNOP00000025165
(RGD:1564895)
Saccharomyces cerevisiae (Sce) sce1759 YER043C
(S000000845)
Schizosaccharomyces pombe (Spo) spo3367 SPBC8D2.18c O13639
Yarrowia lipolytica (Yli) yli5837 YALI0F11759g