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Search term: YER051W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name JHD1
SGD link S000000853
Alternative ID YER051W
Description JmjC domain family histone demethylase specific for H3-K36, similar to proteins found in human, mouse, drosophila, X. laevis, C. elegans, and S. pombe
Synonyms YER051W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1633 -CDHYP-

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING F-box protein JEMMA and related proteins with JmjC, PHD, F-box and LRR domains

Species KOG link NCBI link UniProt link
Caenorhabditis elegans (Cel) CE09781
(WBGene00017920)		 GI:17540064 Q9GYI0
Caenorhabditis elegans (Cel) CE20788
(WBGene00005013)		 GI:17533997 Q20367
Caenorhabditis elegans (Cel) CE27145 GI:17540066 Q9GYI0
Caenorhabditis elegans (Cel) CE29354 GI:17555290
Caenorhabditis elegans (Cel) CE29355 GI:17555288
Drosophila melanogaster (Dme) 7299136_1 GI:7299136
Homo sapiens (Hsa) Hs16306580_1
(KDM2A)		 GI:16306580 Q9Y2K7
Homo sapiens (Hsa) Hs20548284 GI:20548284
Homo sapiens (Hsa) Hs22047187 GI:22047187
Homo sapiens (Hsa) Hs22047606 GI:22047606
Homo sapiens (Hsa) Hs22053635 GI:22053635
Homo sapiens (Hsa) Hs22055516 GI:22055516
Homo sapiens (Hsa) Hs22057112_1 GI:22057112
Homo sapiens (Hsa) Hs22069613 GI:22069613
Homo sapiens (Hsa) Hs4885547 GI:4885547
Saccharomyces cerevisiae (Sce) YER051w
(S000000853)		 GI:6320892 P40034
Schizosaccharomyces pombe (Spo) SPCC622.16c GI:19075688 O94603


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
SceS000000853
GO:0005634 nucleus C
IDA
CelWBGene00017920
SpoSPCC622.16c
GO:0005720 nuclear heterochromatin C
IDA
SpoSPCC622.16c
GO:0005816 spindle pole body C
IDA
SpoSPCC622.16c
GO:0005515 protein binding F
IPI
HsaKDM2A
SpoSPCC622.16c
GO:0032454 histone demethylase activity (H3-K9
specific)		 F
IDA
CelWBGene00017920
IMP
CelWBGene00017920
GO:0035064 methylated histone residue binding F
IDA
SceS000000853
GO:0051864 histone demethylase activity (H3-K36
specific)		 F
IDA
SceS000000853
IMP
SceS000000853
GO:0071558 histone demethylase activity (H3-K27
specific)		 F
IDA
CelWBGene00017920
IMP
CelWBGene00017920
GO:0001672 regulation of chromatin assembly or
disassembly		 P
IMP
SpoSPCC622.16c
GO:0006338 chromatin remodeling P
IMP
SpoSPCC622.16c
GO:0006357 regulation of transcription from RNA polymerase II
promoter		 P
IMP
SpoSPCC622.16c
GO:0007059 chromosome segregation P
IMP
SpoSPCC622.16c
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00017920
GO:0016577 histone demethylation P
IDA
SceS000000853
IMP
SceS000000853
GO:0031454 regulation of extent of heterochromatin
formation		 P
IMP
SpoSPCC622.16c
GO:0033169 histone H3-K9 demethylation P
IDA
CelWBGene00017920
IMP
CelWBGene00017920
GO:0040012 regulation of locomotion P
IMP
CelWBGene00017920
GO:0071557 histone H3-K27 demethylation P
IDA
CelWBGene00017920
IMP
CelWBGene00017920
GO:0090052 regulation of chromatin silencing at
centromere		 P
IMP
SpoSPCC622.16c
GO:0090054 regulation of chromatin silencing at silent
mating-type cassette		 P
IMP
SpoSPCC622.16c

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
49405

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) PHF8 GI:32698700
Pan troglodytes (Ptr) PHF8 GI:114688773
Canis familiaris (Cfa) PHF8 GI:74007015
Mus musculus (Mmu) Phf8
(MGI:2444341)		 GI:28893223 A2ABV3
Saccharomyces cerevisiae (Sce) JHD1
(S000000853)		 GI:6320892 P40034
Kluyveromyces lactis (Kla) KLLA0F27643g GI:50312549
Eremothecium gossypii (Ego) AGOS_ADL088W GI:45187785


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
MmuMGI:2444341
SceS000000853
GO:0005634 nucleus C
IC
HsaPHF8
IDA
HsaPHF8
GO:0005730 nucleolus C
IDA
HsaPHF8
GO:0003674 molecular_function F
ND
MmuMGI:2444341
GO:0003682 chromatin binding F
IDA
HsaPHF8
GO:0005506 iron ion binding F
IDA
HsaPHF8
GO:0005515 protein binding F
IPI
HsaPHF8
GO:0008270 zinc ion binding F
IDA
HsaPHF8
GO:0016706 oxidoreductase activity, acting on paired donors,
with incorporation or reduction of molecular
oxygen, 2-oxoglutarate as one donor, and
incorporation of one atom each of oxygen into both
donors		 F
IDA
HsaPHF8
GO:0032452 histone demethylase activity F
IDA
HsaPHF8
GO:0032454 histone demethylase activity (H3-K9
specific)		 F
IDA
HsaPHF8
GO:0035064 methylated histone residue binding F
IDA
HsaPHF8
SceS000000853
GO:0035575 histone demethylase activity (H4-K20
specific)		 F
IDA
HsaPHF8
GO:0051864 histone demethylase activity (H3-K36
specific)		 F
IDA
HsaPHF8
SceS000000853
IMP
SceS000000853
GO:0071558 histone demethylase activity (H3-K27
specific)		 F
IDA
HsaPHF8
GO:0000082 G1/S transition of mitotic cell
cycle		 P
IMP
HsaPHF8
GO:0008150 biological_process P
ND
MmuMGI:2444341
GO:0016577 histone demethylation P
IDA
SceS000000853
IMP
SceS000000853
GO:0033169 histone H3-K9 demethylation P
IDA
HsaPHF8
GO:0035574 histone H4-K20 demethylation P
IDA
HsaPHF8
GO:0045893 positive regulation of transcription,
DNA-dependent		 P
IDA
HsaPHF8
IMP
HsaPHF8
GO:0045943 positive regulation of transcription from RNA
polymerase I promoter		 P
IDA
HsaPHF8
GO:0061188 negative regulation of chromatin silencing at
rDNA		 P
IDA
HsaPHF8
GO:0070544 histone H3-K36 demethylation P
IDA
HsaPHF8
GO:0071557 histone H3-K27 demethylation P
IDA
HsaPHF8

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1361

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga3996 ENSANGP00000007938
Ashbya gossypii (Ago) ago1653 ADL088W
Caenorhabditis elegans (Cel) cel16374 T26A5.5a
(CE32733;
WBGene00020821)
Caenorhabditis elegans (Cel) cel16375 T26A5.5b
(CE32734)
Candida glabrata (Cgl) cgl3111 CAGL0J02860g
Cryptococcus neoformans (Cne) cne4155 177.m02914
Debaryomyces hansenii (Dha) dha792 DEHA0B02519g
Drosophila melanogaster (Dme) dme11637 CG11033-PA
(FBgn0037659)
Danio rerio (Dre) dre25905 ENSDARP00000015487
Danio rerio (Dre) dre28863 ENSDARP00000024032
Danio rerio (Dre) dre30616 ENSDARP00000027250
Danio rerio (Dre) dre30617 ENSDARP00000038635
Danio rerio (Dre) dre28862 ENSDARP00000040956
Danio rerio (Dre) dre28864 ENSDARP00000042784
(LOC558032)
Takifugu rubripes (Fru) fru22000 SINFRUP00000147534
Takifugu rubripes (Fru) fru22001 SINFRUP00000147539
Takifugu rubripes (Fru) fru15882 SINFRUP00000149358
Takifugu rubripes (Fru) fru15883 SINFRUP00000149359
Takifugu rubripes (Fru) fru12027 SINFRUP00000160259
Takifugu rubripes (Fru) fru32442 SINFRUP00000165570
Takifugu rubripes (Fru) fru32440 SINFRUP00000165571
Takifugu rubripes (Fru) fru12029 SINFRUP00000169032
Takifugu rubripes (Fru) fru12028 SINFRUP00000171233
Takifugu rubripes (Fru) fru32441 SINFRUP00000171889
Gallus gallus (Gga) gga7215 ENSGALP00000006714
(FBXL10)
Gallus gallus (Gga) gga7217 ENSGALP00000006715
Gallus gallus (Gga) gga7216 ENSGALP00000006716
Gallus gallus (Gga) gga26313 ENSGALP00000021661
(FBXL11)
Homo sapiens (Hsa) hsa8343 ENSP00000261824
(KDM2B)		 Q8NHM5-2
Homo sapiens (Hsa) hsa6057 ENSP00000309302
(KDM2A)		 Q9Y2K7-2
Kluyveromyces lactis (Kla) kla5310 KLLA0F27643g
Mus musculus (Mmu) mmu20894 ENSMUSP00000038229
(MGI:1354737)		 Q6P1G2-1
Rattus norvegicus (Rno) rno8579 ENSRNOP00000001803
(RGD:1310217)		 Q641Z3
Rattus norvegicus (Rno) rno3448 ENSRNOP00000025969
Rattus norvegicus (Rno) rno8578 ENSRNOP00000042993
(RGD:1310217)
Rattus norvegicus (Rno) rno8577 ENSRNOP00000050408
(RGD:1310217)
Saccharomyces cerevisiae (Sce) sce1770 YER051W
(S000000853)
Schizosaccharomyces pombe (Spo) spo2746 SPCC622.16c O94603


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
SceS000000853
GO:0005634 nucleus C
IDA
SpoSPCC622.16c
GO:0005720 nuclear heterochromatin C
IDA
SpoSPCC622.16c
GO:0005816 spindle pole body C
IDA
SpoSPCC622.16c
GO:0005515 protein binding F
IPI
MmuMGI:1354737
SpoSPCC622.16c
GO:0035064 methylated histone residue binding F
IDA
SceS000000853
GO:0051864 histone demethylase activity (H3-K36
specific)		 F
IDA
SceS000000853
IMP
SceS000000853
GO:0000003 reproduction P
IMP
CelWBGene00020821
GO:0001672 regulation of chromatin assembly or
disassembly		 P
IMP
SpoSPCC622.16c
GO:0006338 chromatin remodeling P
IMP
SpoSPCC622.16c
GO:0006357 regulation of transcription from RNA polymerase II
promoter		 P
IMP
SpoSPCC622.16c
GO:0006974 response to DNA damage stimulus P
IMP
CelWBGene00020821
GO:0007059 chromosome segregation P
IMP
SpoSPCC622.16c
GO:0016577 histone demethylation P
IDA
SceS000000853
IMP
SceS000000853
GO:0031454 regulation of extent of heterochromatin
formation		 P
IMP
SpoSPCC622.16c
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00020821
GO:0090052 regulation of chromatin silencing at
centromere		 P
IMP
SpoSPCC622.16c
GO:0090054 regulation of chromatin silencing at silent
mating-type cassette		 P
IMP
SpoSPCC622.16c

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPCC622.16c
(O94603)		 YER051W
(S000000853)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
SceS000000853
GO:0005634 nucleus C
IDA
SpoSPCC622.16c
GO:0005720 nuclear heterochromatin C
IDA
SpoSPCC622.16c
GO:0005816 spindle pole body C
IDA
SpoSPCC622.16c
GO:0005515 protein binding F
IPI
SpoSPCC622.16c
GO:0035064 methylated histone residue binding F
IDA
SceS000000853
GO:0051864 histone demethylase activity (H3-K36
specific)		 F
IDA
SceS000000853
IMP
SceS000000853
GO:0001672 regulation of chromatin assembly or
disassembly		 P
IMP
SpoSPCC622.16c
GO:0006338 chromatin remodeling P
IMP
SpoSPCC622.16c
GO:0006357 regulation of transcription from RNA polymerase II
promoter		 P
IMP
SpoSPCC622.16c
GO:0007059 chromosome segregation P
IMP
SpoSPCC622.16c
GO:0016577 histone demethylation P
IDA
SceS000000853
IMP
SceS000000853
GO:0031454 regulation of extent of heterochromatin
formation		 P
IMP
SpoSPCC622.16c
GO:0090052 regulation of chromatin silencing at
centromere		 P
IMP
SpoSPCC622.16c
GO:0090054 regulation of chromatin silencing at silent
mating-type cassette		 P
IMP
SpoSPCC622.16c

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Search for gene by ID or name:

Query species:

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Search for GO info:  

GO info in one table:

s.khadayate@ucl.ac.uk