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Search term: YER057C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name HMF1
SGD link S000000859
Alternative ID YER057C
Description Member of the p14.5 protein family with similarity to Mmf1p, functionally complements Mmf1p function when targeted to mitochondria; heat shock inducible; high-dosage growth inhibitor; forms a homotrimer in vitro
Synonyms YER057C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2317 ACDHYP-

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING Putative translation initiation inhibitor UK114/IBM1

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At3g04480_2 GI:15229304
Arabidopsis thaliana (Ath) At3g20390 GI:15231137
Caenorhabditis elegans (Cel) CE01809 GI:17552260
Drosophila melanogaster (Dme) 7292700_2 GI:7292700
Drosophila melanogaster (Dme) 7298219
(UK114)		 GI:19921376
Homo sapiens (Hsa) Hs5032215
(HRSP12)		 GI:5032215 P52758
Saccharomyces cerevisiae (Sce) YER057c
(S000000859)		 GI:6320899 P40037
Saccharomyces cerevisiae (Sce) YIL051c
(S000001313)		 GI:6322138 P40185
Saccharomyces cerevisiae (Sce) YLR143w_2 GI:6323172 Q12429
Schizosaccharomyces pombe (Spo) SPAC1039.10 GI:19115913 Q9UR06
Schizosaccharomyces pombe (Spo) SPBC2G2.04c GI:19113225 O43003
Schizosaccharomyces pombe (Spo) SPBC577.12_2 GI:19112102 Q9USQ7


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000000859
SpoSPBC577.12
SPBC2G2.04c
ISS
SpoSPAC1039.10
GO:0005737 cytoplasm C
IDA
SceYLR143w
S000000859
SpoSPBC2G2.04c
ISS
SpoSPAC1039.10
SPBC577.12
GO:0005739 mitochondrion C
IDA
AthAt3g20390
SceS000001313
GO:0005759 mitochondrial matrix C
IDA
SceS000001313
SpoSPBC2G2.04c
GO:0005773 vacuole C
IDA
AthAt3g20390
GO:0005829 cytosol C
IDA
SceS000000859
SpoSPBC2G2.04c
SPBC577.12
GO:0009507 chloroplast C
IDA
AthAt3g20390
GO:0009536 plastid C
IDA
AthAt3g20390
GO:0009579 thylakoid C
IDA
AthAt3g20390
GO:0003674 molecular_function F
ND
SceYLR143w
S000000859
S000001313
SpoSPAC1039.10
SPBC2G2.04c
GO:0004521 endoribonuclease activity F
ISS
AthAt3g20390
At3g04480
SpoSPBC577.12
GO:0000002 mitochondrial genome maintenance P
IMP
SpoSPBC2G2.04c
GO:0006449 regulation of translational termination P
TAS
HsaHRSP12
GO:0006457 protein folding P
IDA
DmeUK114
GO:0008150 biological_process P
ND
AthAt3g04480
SceYLR143w
S000000859
SpoSPBC577.12
GO:0009097 isoleucine biosynthetic process P
IMP
SceS000001313
ISS
SpoSPAC1039.10
GO:0017148 negative regulation of translation P
ISS
DmeUK114
GO:0032543 mitochondrial translation P
IGI
SceS000001313
GO:0046686 response to cadmium ion P
IEP
AthAt3g20390

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
101582

Species Gene ID NCBI link UniProt link
Schizosaccharomyces pombe (Spo) mmf1
(SPBC2G2.04c)		 GI:19113225 O43003
Schizosaccharomyces pombe (Spo) hpm1 GI:19115913
Saccharomyces cerevisiae (Sce) HMF1
(S000000859)		 GI:6320899 P40037
Kluyveromyces lactis (Kla) KLLA0C08349g GI:50305225
Eremothecium gossypii (Ego) AGOS_ADL077C GI:45187796
Magnaporthe grisea (Mgr) MGG_04426 GI:145614640
Neurospora crassa (Ncr) NCU09331.1 GI:32423171


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000000859
SpoSPBC2G2.04c
GO:0005737 cytoplasm C
IDA
SceS000000859
SpoSPBC2G2.04c
GO:0005759 mitochondrial matrix C
IDA
SpoSPBC2G2.04c
GO:0005829 cytosol C
IDA
SceS000000859
SpoSPBC2G2.04c
GO:0003674 molecular_function F
ND
SceS000000859
SpoSPBC2G2.04c
GO:0000002 mitochondrial genome maintenance P
IMP
SpoSPBC2G2.04c
GO:0008150 biological_process P
ND
SceS000000859

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_756

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga738 ENSANGP00000021077
Ashbya gossypii (Ago) ago1664 ADL077C
Arabidopsis thaliana (Ath) ath14334 At3g20390.1
Caenorhabditis elegans (Cel) cel2483 C23G10.2a
(CE37747;
WBGene00016011)
Caenorhabditis elegans (Cel) cel2484 C23G10.2b
(CE30613)
Caenorhabditis elegans (Cel) cel2485 C23G10.2c
(CE37748)
Candida glabrata (Cgl) cgl5195 CAGL0M12386g
Cryptococcus neoformans (Cne) cne3504 176.m02228
Cryptococcus neoformans (Cne) cne1148 180.m00075
Cryptococcus neoformans (Cne) cne4630 186.m03474
Cryptococcus neoformans (Cne) cne5064 186.m03996
Dictyostelium discoideum (Ddi) ddi1399 DDB0167437
Dictyostelium discoideum (Ddi) ddi6972 DDB0169400
Debaryomyces hansenii (Dha) dha3002 DEHA0D15686g
Debaryomyces hansenii (Dha) dha6629 DEHA0G20801g
Drosophila melanogaster (Dme) dme2498 CG15261-PA
(FBgn0028510)
Escherichia coli (Eco) eco4085 16132065
Escherichia coli (Eco) eco3008 49176315
Takifugu rubripes (Fru) fru9366 SINFRUP00000147876
Takifugu rubripes (Fru) fru20151 SINFRUP00000171495
Gallus gallus (Gga) gga27228 ENSGALP00000028191
Homo sapiens (Hsa) hsa30563 ENSP00000254878
(HRSP12)		 P52758
Kluyveromyces lactis (Kla) kla1189 KLLA0B14817g
Kluyveromyces lactis (Kla) kla1570 KLLA0C08349g
Kluyveromyces lactis (Kla) kla3123 KLLA0E03894g
Mus musculus (Mmu) mmu8868 ENSMUSP00000022946
(MGI:1095401)		 P52760
Neurospora crassa (Ncr) ncr9919 NCU10226.2
Oryza sativa (Osa) osa4699 2117.m00133
Oryza sativa (Osa) osa52947 6120.m00110
Rattus norvegicus (Rno) rno26948 ENSRNOP00000007430
(RGD:70940)		 P52759
Saccharomyces cerevisiae (Sce) sce1778 YER057C
(S000000859)
Saccharomyces cerevisiae (Sce) sce3067 YIL051C
(S000001313)
Schizosaccharomyces pombe (Spo) spo2527 SPAC1039.10 Q9UR06
Schizosaccharomyces pombe (Spo) spo1110 SPBC2G2.04c O43003
Yarrowia lipolytica (Yli) yli2120 YALI0C09735g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000000859
SpoSPBC2G2.04c
ISS
SpoSPAC1039.10
GO:0005737 cytoplasm C
IDA
SceS000000859
SpoSPBC2G2.04c
ISS
SpoSPAC1039.10
GO:0005739 mitochondrion C
IDA
AthAt3g20390
MmuMGI:1095401
SceS000001313
GO:0005759 mitochondrial matrix C
IDA
SceS000001313
SpoSPBC2G2.04c
GO:0005773 vacuole C
IDA
AthAt3g20390
GO:0005829 cytosol C
IDA
SceS000000859
SpoSPBC2G2.04c
GO:0009507 chloroplast C
IDA
AthAt3g20390
GO:0009536 plastid C
IDA
AthAt3g20390
GO:0009579 thylakoid C
IDA
AthAt3g20390
GO:0003674 molecular_function F
ND
SceS000000859
S000001313
SpoSPAC1039.10
SPBC2G2.04c
GO:0004521 endoribonuclease activity F
ISS
AthAt3g20390
GO:0000002 mitochondrial genome maintenance P
IMP
SpoSPBC2G2.04c
GO:0008150 biological_process P
ND
SceS000000859
GO:0009097 isoleucine biosynthetic process P
IMP
SceS000001313
ISS
SpoSPAC1039.10
GO:0032543 mitochondrial translation P
IGI
SceS000001313
GO:0046686 response to cadmium ion P
IEP
AthAt3g20390

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC1039.10
(Q9UR06)		 YER057C
(S000000859)
SPBC2G2.04c
(O43003)		 YER057C
(S000000859)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000000859
SpoSPBC2G2.04c
ISS
SpoSPAC1039.10
GO:0005737 cytoplasm C
IDA
SceS000000859
SpoSPBC2G2.04c
ISS
SpoSPAC1039.10
GO:0005759 mitochondrial matrix C
IDA
SpoSPBC2G2.04c
GO:0005829 cytosol C
IDA
SceS000000859
SpoSPBC2G2.04c
GO:0003674 molecular_function F
ND
SceS000000859
SpoSPAC1039.10
SPBC2G2.04c
GO:0000002 mitochondrial genome maintenance P
IMP
SpoSPBC2G2.04c
GO:0008150 biological_process P
ND
SceS000000859
GO:0009097 isoleucine biosynthetic process P
ISS
SpoSPAC1039.10

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