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Search term: YER065C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name ICL1
SGD link S000000867
Alternative ID YER065C
Description Isocitrate lyase, catalyzes the formation of succinate and glyoxylate from isocitrate, a key reaction of the glyoxylate cycle; expression of ICL1 is induced by growth on ethanol and repressed by growth on glucose
Synonyms YER065C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1260 AC--YP-

KOGs classification KOGs description
METABOLISM Isocitrate lyase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g21440 GI:15218989
Arabidopsis thaliana (Ath) At1g77060 GI:15223832
Arabidopsis thaliana (Ath) At2g43180 GI:15224239
Arabidopsis thaliana (Ath) At3g21720 GI:15233130
Caenorhabditis elegans (Cel) CE23521_1 GI:17561814 Q10663
Caenorhabditis elegans (Cel) CE23529_1 GI:17538588
Saccharomyces cerevisiae (Sce) YER065c
(S000000867)		 GI:6320908 P28240
Saccharomyces cerevisiae (Sce) YPR006c
(S000006210)		 GI:6325263 Q12031
Schizosaccharomyces pombe (Spo) SPBC1683.11c GI:19111859 Q9P6J1
Arabidopsis thaliana (Ath) At1g21440 GI:15218989
Arabidopsis thaliana (Ath) At1g77060 GI:15223832
Arabidopsis thaliana (Ath) At2g43180 GI:15224239
Arabidopsis thaliana (Ath) At3g21720 GI:15233130
Caenorhabditis elegans (Cel) CE23521_1 GI:17561814 Q10663
Caenorhabditis elegans (Cel) CE23529_1 GI:17538588
Saccharomyces cerevisiae (Sce) YER065c
(S000000867)		 GI:6320908 P28240
Saccharomyces cerevisiae (Sce) YPR006c
(S000006210)		 GI:6325263 Q12031
Schizosaccharomyces pombe (Spo) SPBC1683.11c GI:19111859 Q9P6J1


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt3g21720
SceS000000867
GO:0005739 mitochondrion C
IDA
SceS000006210
GO:0005759 mitochondrial matrix C
IDA
SceS000006210
ISS
SpoSPBC1683.11c
GO:0005829 cytosol C
IDA
SpoSPBC1683.11c
GO:0009507 chloroplast C
IDA
AthAt2g43180
At1g21440
At1g77060
GO:0009570 chloroplast stroma C
IDA
AthAt1g21440
At1g77060
GO:0004451 isocitrate lyase activity F
IMP
SceS000000867
ISS
AthAt1g21440
At3g21720
CelWBGene00001564
SceS000000867
GO:0004474 malate synthase activity F
ISS
CelWBGene00001564
GO:0046421 methylisocitrate lyase activity F
IDA
SceS000006210
ISS
SpoSPBC1683.11c
GO:0006097 glyoxylate cycle P
ISS
CelWBGene00001564
TAS
SceS000000867
GO:0006567 threonine catabolic process P
IEP
SceS000006210
ISS
SpoSPBC1683.11c
GO:0008152 metabolic process P
ISS
AthAt3g21720
GO:0008340 determination of adult lifespan P
IGI
CelWBGene00001564
IMP
CelWBGene00001564
GO:0009790 embryo development P
IPI
CelWBGene00001564
GO:0019541 propionate metabolic process P
IDA
SceS000006210
IEP
SceS000006210
ISS
SpoSPBC1683.11c
GO:0055114 oxidation reduction P
RCA
SceS000006210

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
5823

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) ICL1
(S000000867)		 GI:6320908 P28240
Kluyveromyces lactis (Kla) KLLA0C08107g GI:50305203
Eremothecium gossypii (Ego) AGOS_ADL066C GI:45187807
Magnaporthe grisea (Mgr) MGG_04895 GI:39940690
Neurospora crassa (Ncr) NCU04230.1 GI:32405914
Arabidopsis thaliana (Ath) ICL GI:30686361
Oryza sativa (Osa) Os07g0529000 GI:115472481


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthICL
SceS000000867
GO:0004451 isocitrate lyase activity F
IMP
SceS000000867
ISS
AthICL
SceS000000867
GO:0006097 glyoxylate cycle P
TAS
SceS000000867
GO:0008152 metabolic process P
ISS
AthICL

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_3627

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga13865 ENSANGP00000027962
Anopheles gambiae (Aga) aga13864 ENSANGP00000028888
Ashbya gossypii (Ago) ago1675 ADL066C
Ashbya gossypii (Ago) ago4254 AGL057W
Arabidopsis thaliana (Ath) ath14477 At3g21720.1
Candida glabrata (Cgl) cgl3120 CAGL0J03058g
Candida glabrata (Cgl) cgl4483 CAGL0L09273g
Dictyostelium discoideum (Ddi) ddi12051 DDB0230179
Debaryomyces hansenii (Dha) dha2933 DEHA0D14212g
Escherichia coli (Eco) eco3860 16131841
Kluyveromyces lactis (Kla) kla1559 KLLA0C08107g
Kluyveromyces lactis (Kla) kla3577 KLLA0E13948g
Neurospora crassa (Ncr) ncr4106 NCU04230.2
Oryza sativa (Osa) osa73371 7272.m00151
Oryza sativa (Osa) osa73383 7272.m00184
Saccharomyces cerevisiae (Sce) sce1787 YER065C
(S000000867)
Saccharomyces cerevisiae (Sce) sce6459 YPR006C
(S000006210)
Schizosaccharomyces pombe (Spo) spo1286 SPBC1683.11c Q9P6J1
Yarrowia lipolytica (Yli) yli2403 YALI0C16885g
Yarrowia lipolytica (Yli) yli6660 YALI0F31999g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt3g21720
SceS000000867
GO:0005739 mitochondrion C
IDA
SceS000006210
GO:0005759 mitochondrial matrix C
IDA
SceS000006210
ISS
SpoSPBC1683.11c
GO:0005829 cytosol C
IDA
SpoSPBC1683.11c
GO:0004451 isocitrate lyase activity F
IMP
SceS000000867
ISS
AthAt3g21720
SceS000000867
GO:0046421 methylisocitrate lyase activity F
IDA
SceS000006210
ISS
SpoSPBC1683.11c
GO:0006097 glyoxylate cycle P
TAS
SceS000000867
GO:0006567 threonine catabolic process P
IEP
SceS000006210
ISS
SpoSPBC1683.11c
GO:0008152 metabolic process P
ISS
AthAt3g21720
GO:0019541 propionate metabolic process P
IDA
SceS000006210
IEP
SceS000006210
ISS
SpoSPBC1683.11c
GO:0055114 oxidation reduction P
RCA
SceS000006210

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC1683.11c
(Q9P6J1)		 YER065C
(S000000867)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
SceS000000867
GO:0005759 mitochondrial matrix C
ISS
SpoSPBC1683.11c
GO:0005829 cytosol C
IDA
SpoSPBC1683.11c
GO:0004451 isocitrate lyase activity F
IMP
SceS000000867
ISS
SceS000000867
GO:0046421 methylisocitrate lyase activity F
ISS
SpoSPBC1683.11c
GO:0006097 glyoxylate cycle P
TAS
SceS000000867
GO:0006567 threonine catabolic process P
ISS
SpoSPBC1683.11c
GO:0019541 propionate metabolic process P
ISS
SpoSPBC1683.11c

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