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Search term: YER078C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name ICP55
SGD link S000000880
Alternative ID YER078C
Description Mitochondrial aminopeptidase; cleaves the N termini of at least 38 imported proteins after cleavage by the mitochondrial processing peptidase (MPP), thereby increasing their stability; member of the aminopeptidase P family
Synonyms YER078C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2414 ACDHYP-

KOGs classification KOGs description
METABOLISM Putative Xaa-Pro aminopeptidase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g09300 GI:15217481
Caenorhabditis elegans (Cel) CE18156 GI:17508649
Drosophila melanogaster (Dme) 7289280
(FBgn0031093)		 GI:19920384
Drosophila melanogaster (Dme) 7296571 GI:7296571
Homo sapiens (Hsa) Hs11559925
(XPNPEP3)		 GI:11559925 Q9NQH7
Saccharomyces cerevisiae (Sce) YER078c
(S000000880)		 GI:6320922 P40051
Schizosaccharomyces pombe (Spo) SPAC12B10.05 GI:19115549 Q10439


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000000880
GO:0005739 mitochondrion C
IDA
SceS000000880
SpoSPAC12B10.05
ISS
SpoSPAC12B10.05
GO:0031314 extrinsic to mitochondrial inner
membrane		 C
IDA
SceS000000880
GO:0004177 aminopeptidase activity F
IDA
SceS000000880
IMP
SceS000000880
ISS
DmeFBgn0031093
GO:0008237 metallopeptidase activity F
ISS
AthAt1g09300
GO:0070006 metalloaminopeptidase activity F
ISS
SpoSPAC12B10.05
GO:0007005 mitochondrion organization P
IC
SpoSPAC12B10.05
GO:0034982 mitochondrial protein processing P
ISS
SpoSPAC12B10.05
GO:0050821 protein stabilization P
IMP
SceS000000880
GO:0051605 protein maturation by peptide bond
cleavage		 P
IGI
SceS000000880
IMP
SceS000000880
ISS
SpoSPAC12B10.05

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
74662

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) YER078C
(S000000880)		 GI:6320922 P40051
Kluyveromyces lactis (Kla) KLLA0C07645g GI:50305163


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000000880
GO:0005739 mitochondrion C
IDA
SceS000000880
GO:0031314 extrinsic to mitochondrial inner
membrane		 C
IDA
SceS000000880
GO:0004177 aminopeptidase activity F
IDA
SceS000000880
IMP
SceS000000880
GO:0050821 protein stabilization P
IMP
SceS000000880
GO:0051605 protein maturation by peptide bond
cleavage		 P
IGI
SceS000000880
IMP
SceS000000880

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2560

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga15575 ENSANGP00000017831
Ashbya gossypii (Ago) ago1021 ACL028W
Arabidopsis thaliana (Ath) ath950 At1g09300.1
Caenorhabditis elegans (Cel) cel13817 R119.2
(CE34356;
WBGene00020088)
Candida glabrata (Cgl) cgl3131 CAGL0J03300g
Cryptococcus neoformans (Cne) cne5636 179.m00498
Dictyostelium discoideum (Ddi) ddi5376 DDB0218347
Debaryomyces hansenii (Dha) dha1282 DEHA0B13849g
Drosophila melanogaster (Dme) dme18740 CG9581-PA
(FBgn0031093)
Danio rerio (Dre) dre17417 ENSDARP00000014742
Danio rerio (Dre) dre17414 ENSDARP00000018679
Danio rerio (Dre) dre17418 ENSDARP00000042757
Danio rerio (Dre) dre17415 ENSDARP00000050244
(zgc:76905)		 Q6NYT0
Escherichia coli (Eco) eco2810 16130810
Takifugu rubripes (Fru) fru30892 SINFRUP00000136027
Takifugu rubripes (Fru) fru30893 SINFRUP00000173806
Gallus gallus (Gga) gga850 ENSGALP00000019561
Gallus gallus (Gga) gga848 ENSGALP00000019563
(XPNPEP3)
Gallus gallus (Gga) gga849 ENSGALP00000019564
Homo sapiens (Hsa) hsa21726 ENSP00000349658
(XPNPEP3)		 Q9NQH7-1
Kluyveromyces lactis (Kla) kla1539 KLLA0C07645g
Mus musculus (Mmu) mmu9348 ENSMUSP00000038331
(MGI:2445217)		 Q8BHT9
Neurospora crassa (Ncr) ncr5804 NCU05971.2
Oryza sativa (Osa) osa68809 7028.m00123
Oryza sativa (Osa) osa68828 7028.m00162
Rattus norvegicus (Rno) rno27447 ENSRNOP00000030355
(RGD:1589063)
Saccharomyces cerevisiae (Sce) sce1805 YER078C
(S000000880)
Schizosaccharomyces pombe (Spo) spo1438 SPAC12B10.05 Q10439
Yarrowia lipolytica (Yli) yli1589 YALI0B20394g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000000880
GO:0005739 mitochondrion C
IDA
MmuMGI:2445217
SceS000000880
SpoSPAC12B10.05
ISS
SpoSPAC12B10.05
GO:0031314 extrinsic to mitochondrial inner
membrane		 C
IDA
SceS000000880
GO:0003674 molecular_function F
ND
MmuMGI:2445217
GO:0004177 aminopeptidase activity F
IDA
SceS000000880
IMP
SceS000000880
ISS
DmeFBgn0031093
GO:0008237 metallopeptidase activity F
ISS
AthAt1g09300
GO:0070006 metalloaminopeptidase activity F
ISS
SpoSPAC12B10.05
GO:0007005 mitochondrion organization P
IC
SpoSPAC12B10.05
GO:0008150 biological_process P
ND
MmuMGI:2445217
GO:0034982 mitochondrial protein processing P
ISS
SpoSPAC12B10.05
GO:0050821 protein stabilization P
IMP
SceS000000880
GO:0051605 protein maturation by peptide bond
cleavage		 P
IGI
SceS000000880
IMP
SceS000000880
ISS
SpoSPAC12B10.05

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC12B10.05
(Q10439)		 YER078C
(S000000880)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000000880
GO:0005739 mitochondrion C
IDA
SceS000000880
SpoSPAC12B10.05
ISS
SpoSPAC12B10.05
GO:0031314 extrinsic to mitochondrial inner
membrane		 C
IDA
SceS000000880
GO:0004177 aminopeptidase activity F
IDA
SceS000000880
IMP
SceS000000880
GO:0070006 metalloaminopeptidase activity F
ISS
SpoSPAC12B10.05
GO:0007005 mitochondrion organization P
IC
SpoSPAC12B10.05
GO:0034982 mitochondrial protein processing P
ISS
SpoSPAC12B10.05
GO:0050821 protein stabilization P
IMP
SceS000000880
GO:0051605 protein maturation by peptide bond
cleavage		 P
IGI
SceS000000880
IMP
SceS000000880
ISS
SpoSPAC12B10.05

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