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Search term: YER093C


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name TSC11
SGD link S000000895
Alternative ID YER093C
Description Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p), a membrane-associated complex that regulates actin cytoskeletal dynamics during polarized growth and cell wall integrity; involved in sphingolipid metabolism; contains a RasGEFN domain
Synonyms YER093C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG3694 -CDHYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Protein required for meiosis

Species KOG link NCBI link UniProt link
Caenorhabditis elegans (Cel) CE20734 GI:17533569
Caenorhabditis elegans (Cel) CE23689_1 GI:17533567
Drosophila melanogaster (Dme) 7293569 GI:7293569
Homo sapiens (Hsa) Hs20541778 GI:20541778
Homo sapiens (Hsa) Hs22047806 GI:20810349 Q8N6M7
Saccharomyces cerevisiae (Sce) YER093c
(S000000895)
GI:6320939 P40061
Schizosaccharomyces pombe (Spo) SPBC12C2.02c GI:19112813 Q09743


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005624 membrane fraction C
IDA
SceS000000895
GO:0005634 nucleus C
IDA
SpoSPBC12C2.02c
GO:0005737 cytoplasm C
IDA
SpoSPBC12C2.02c
GO:0005829 cytosol C
IDA
SpoSPBC12C2.02c
GO:0031932 TORC2 complex C
IDA
SpoSPBC12C2.02c
IPI
SceS000000895
GO:0032153 cell division site C
IDA
SpoSPBC12C2.02c
GO:0003674 molecular_function F
ND
SpoSPBC12C2.02c
GO:0005515 protein binding F
IPI
SceS000000895
GO:0001558 regulation of cell growth P
IPI
SceS000000895
GO:0006995 cellular response to nitrogen starvation P
IEP
SpoSPBC12C2.02c
GO:0007264 small GTPase mediated signal transduction P
ISS
SpoSPBC12C2.02c
GO:0030148 sphingolipid biosynthetic process P
IGI
SceS000000895
GO:0030950 establishment or maintenance of actin cytoskeleton
polarity
P
IMP
SceS000000895
IPI
SceS000000895
GO:0031137 regulation of conjugation with cellular
fusion
P
IMP
SpoSPBC12C2.02c
GO:0031505 fungal-type cell wall organization P
IGI
SceS000000895
IMP
SceS000000895
GO:0031929 TOR signaling cascade P
IC
SceS000000895
TAS
SpoSPBC12C2.02c
GO:0051098 regulation of binding P
RCA
SceS000000895

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
34482

Species Gene ID NCBI link UniProt link
Schizosaccharomyces pombe (Spo) ste16
(SPBC12C2.02c)
GI:19112813 Q09743
Saccharomyces cerevisiae (Sce) TSC11
(S000000895)
GI:6320939 P40061
Kluyveromyces lactis (Kla) KLLA0E20229g GI:50309701
Eremothecium gossypii (Ego) AGOS_ABR214C GI:45185446
Magnaporthe grisea (Mgr) MGG_05284 GI:39939912
Neurospora crassa (Ncr) NCU07854.1 GI:32416164


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005624 membrane fraction C
IDA
SceS000000895
GO:0005634 nucleus C
IDA
SpoSPBC12C2.02c
GO:0005737 cytoplasm C
IDA
SpoSPBC12C2.02c
GO:0005829 cytosol C
IDA
SpoSPBC12C2.02c
GO:0031932 TORC2 complex C
IDA
SpoSPBC12C2.02c
IPI
SceS000000895
GO:0032153 cell division site C
IDA
SpoSPBC12C2.02c
GO:0003674 molecular_function F
ND
SpoSPBC12C2.02c
GO:0005515 protein binding F
IPI
SceS000000895
GO:0001558 regulation of cell growth P
IPI
SceS000000895
GO:0006995 cellular response to nitrogen starvation P
IEP
SpoSPBC12C2.02c
GO:0007264 small GTPase mediated signal transduction P
ISS
SpoSPBC12C2.02c
GO:0030148 sphingolipid biosynthetic process P
IGI
SceS000000895
GO:0030950 establishment or maintenance of actin cytoskeleton
polarity
P
IMP
SceS000000895
IPI
SceS000000895
GO:0031137 regulation of conjugation with cellular
fusion
P
IMP
SpoSPBC12C2.02c
GO:0031505 fungal-type cell wall organization P
IGI
SceS000000895
IMP
SceS000000895
GO:0031929 TOR signaling cascade P
IC
SceS000000895
TAS
SpoSPBC12C2.02c
GO:0051098 regulation of binding P
RCA
SceS000000895

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_3279

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Anopheles gambiae (Aga) aga15749 ENSANGP00000016055
Ashbya gossypii (Ago) ago808 ABR214C
Caenorhabditis elegans (Cel) cel7665 F29C12.2
Candida glabrata (Cgl) cgl2736 CAGL0I04950g
Cryptococcus neoformans (Cne) cne1613 164.m02155
Dictyostelium discoideum (Ddi) ddi12270 DDB0185055
Debaryomyces hansenii (Dha) dha468 DEHA0A10494g
Drosophila melanogaster (Dme) dme18597 CG8002-PA
(FBgn0031006)
Danio rerio (Dre) dre13503 ENSDARP00000010467
Danio rerio (Dre) dre28208 ENSDARP00000012945
Danio rerio (Dre) dre28209 ENSDARP00000018675
Danio rerio (Dre) dre13502 ENSDARP00000019140
Takifugu rubripes (Fru) fru712 SINFRUP00000156253
Takifugu rubripes (Fru) fru713 SINFRUP00000156254
Gallus gallus (Gga) gga28341 ENSGALP00000005978
Gallus gallus (Gga) gga28342 ENSGALP00000005979
Gallus gallus (Gga) gga28340 ENSGALP00000005980
Homo sapiens (Hsa) hsa25157 ENSP00000296782
(RICTOR)
Q6R327-3
Homo sapiens (Hsa) hsa25158 ENSP00000349959
(RICTOR)
Q6R327-1
Kluyveromyces lactis (Kla) kla3861 KLLA0E20229g
Mus musculus (Mmu) mmu8732 ENSMUSP00000051809
(MGI:1926007)
Q6QI06-1
Neurospora crassa (Ncr) ncr7650 NCU07854.2
Rattus norvegicus (Rno) rno15604 ENSRNOP00000030782
(RGD:1307224)
Saccharomyces cerevisiae (Sce) sce1829 YER093C
(S000000895)
Schizosaccharomyces pombe (Spo) spo3291 SPBC12C2.02c Q09743
Yarrowia lipolytica (Yli) yli5378 YALI0F01056g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005624 membrane fraction C
IDA
SceS000000895
GO:0005634 nucleus C
IDA
SpoSPBC12C2.02c
GO:0005737 cytoplasm C
IDA
SpoSPBC12C2.02c
GO:0005829 cytosol C
IDA
SpoSPBC12C2.02c
GO:0031932 TORC2 complex C
IDA
SpoSPBC12C2.02c
IPI
MmuMGI:1926007
SceS000000895
ISO
MmuMGI:1926007
GO:0032153 cell division site C
IDA
SpoSPBC12C2.02c
GO:0003674 molecular_function F
ND
SpoSPBC12C2.02c
GO:0005515 protein binding F
IPI
SceS000000895
GO:0001558 regulation of cell growth P
IPI
SceS000000895
GO:0001938 positive regulation of endothelial cell
proliferation
P
ISO
MmuMGI:1926007
GO:0006974 response to DNA damage stimulus P
IMP
DmeFBgn0031006
GO:0006995 cellular response to nitrogen starvation P
IEP
SpoSPBC12C2.02c
GO:0007264 small GTPase mediated signal transduction P
ISS
SpoSPBC12C2.02c
GO:0009790 embryo development P
IMP
MmuMGI:1926007
GO:0030148 sphingolipid biosynthetic process P
IGI
SceS000000895
GO:0030838 positive regulation of actin filament
polymerization
P
IMP
MmuMGI:1926007
GO:0030950 establishment or maintenance of actin cytoskeleton
polarity
P
IMP
SceS000000895
IPI
SceS000000895
GO:0031137 regulation of conjugation with cellular
fusion
P
IMP
SpoSPBC12C2.02c
GO:0031505 fungal-type cell wall organization P
IGI
SceS000000895
IMP
SceS000000895
GO:0031929 TOR signaling cascade P
IC
SceS000000895
TAS
SpoSPBC12C2.02c
GO:0032314 regulation of Rac GTPase activity P
IMP
MmuMGI:1926007
GO:0042325 regulation of phosphorylation P
ISO
MmuMGI:1926007
GO:0048813 dendrite morphogenesis P
IMP
DmeFBgn0031006
GO:0050731 positive regulation of peptidyl-tyrosine
phosphorylation
P
IMP
MmuMGI:1926007
GO:0051098 regulation of binding P
RCA
SceS000000895
GO:0051896 regulation of protein kinase B signaling
cascade
P
IDA
MmuMGI:1926007
GO:0051897 positive regulation of protein kinase B signaling
cascade
P
ISO
MmuMGI:1926007

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPBC12C2.02c
(Q09743)
YER093C
(S000000895)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005624 membrane fraction C
IDA
SceS000000895
GO:0005634 nucleus C
IDA
SpoSPBC12C2.02c
GO:0005737 cytoplasm C
IDA
SpoSPBC12C2.02c
GO:0005829 cytosol C
IDA
SpoSPBC12C2.02c
GO:0031932 TORC2 complex C
IDA
SpoSPBC12C2.02c
IPI
SceS000000895
GO:0032153 cell division site C
IDA
SpoSPBC12C2.02c
GO:0003674 molecular_function F
ND
SpoSPBC12C2.02c
GO:0005515 protein binding F
IPI
SceS000000895
GO:0001558 regulation of cell growth P
IPI
SceS000000895
GO:0006995 cellular response to nitrogen starvation P
IEP
SpoSPBC12C2.02c
GO:0007264 small GTPase mediated signal transduction P
ISS
SpoSPBC12C2.02c
GO:0030148 sphingolipid biosynthetic process P
IGI
SceS000000895
GO:0030950 establishment or maintenance of actin cytoskeleton
polarity
P
IMP
SceS000000895
IPI
SceS000000895
GO:0031137 regulation of conjugation with cellular
fusion
P
IMP
SpoSPBC12C2.02c
GO:0031505 fungal-type cell wall organization P
IGI
SceS000000895
IMP
SceS000000895
GO:0031929 TOR signaling cascade P
IC
SceS000000895
TAS
SpoSPBC12C2.02c
GO:0051098 regulation of binding P
RCA
SceS000000895

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Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:

s.khadayate@ucl.ac.uk