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Search term: YER120W


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name SCS2
SGD link S000000922
Alternative ID YER120W
Description Integral ER membrane protein that regulates phospholipid metabolism via an interaction with the FFAT motif of Opi1p, also involved in telomeric silencing, disruption causes inositol auxotrophy above 34 degrees C, VAP homolog
Synonyms YER120W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0439 ACDHYPE

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING VAMP-associated protein involved in inositol metabolism

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g08820 GI:15223943
Arabidopsis thaliana (Ath) At1g51270 GI:15223792
Arabidopsis thaliana (Ath) At2g23830 GI:15224067
Arabidopsis thaliana (Ath) At2g23860 GI:15224069
Arabidopsis thaliana (Ath) At2g45140 GI:15225415
Arabidopsis thaliana (Ath) At3g60600 GI:11288305
Arabidopsis thaliana (Ath) At4g00170_1 GI:7486542
Arabidopsis thaliana (Ath) At4g05060 GI:5732080
Arabidopsis thaliana (Ath) At4g21450 GI:7485721
Arabidopsis thaliana (Ath) At5g47180 GI:15238034
Arabidopsis thaliana (Ath) At5g54110 GI:8809582
Caenorhabditis elegans (Cel) CE00465_1 GI:17557067
Caenorhabditis elegans (Cel) CE01966
(WBGene00018840)
GI:17534407 P91330
Caenorhabditis elegans (Cel) CE02532
(WBGene00016406)
GI:17550790 Q18438
Caenorhabditis elegans (Cel) CE02813
(WBGene00019410)
GI:17534907 Q21246
Caenorhabditis elegans (Cel) CE03695
(WBGene00011911)
GI:17542484 Q22660
Caenorhabditis elegans (Cel) CE08096
(WBGene00015696)
GI:17505564 P91035
Caenorhabditis elegans (Cel) CE08178 GI:17558002
Caenorhabditis elegans (Cel) CE09902
(WBGene00018008)
GI:17507123 O44782
Caenorhabditis elegans (Cel) CE10068
(WBGene00009550)
GI:17540302
Caenorhabditis elegans (Cel) CE10314_1 GI:17533927 O17099
Caenorhabditis elegans (Cel) CE15068
(WBGene00022546)
GI:17566602 O01630
Caenorhabditis elegans (Cel) CE15322
(WBGene00022708)
GI:17544558 P91567
Caenorhabditis elegans (Cel) CE16148
(WBGene00010184)
GI:17561532 O45592
Caenorhabditis elegans (Cel) CE16345
(WBGene00011478)
GI:17554934 O45751
Caenorhabditis elegans (Cel) CE24750
(WBGene00022833)
GI:17511135 Q9N4M2
Caenorhabditis elegans (Cel) CE25398 GI:17537467
Caenorhabditis elegans (Cel) CE29541_2 GI:17551830
Drosophila melanogaster (Dme) 7290454
(FBgn0029687)
GI:18543325 Q9W4N8
Drosophila melanogaster (Dme) 7295165 GI:7295165
Drosophila melanogaster (Dme) 7295411 GI:7295411
Homo sapiens (Hsa) Hs13122608 GI:13122608 O75425
Homo sapiens (Hsa) Hs17456917 GI:17456917
Homo sapiens (Hsa) Hs20070156 GI:20070156
Homo sapiens (Hsa) Hs4759302
(VAPB)
GI:4759302 O95292
Homo sapiens (Hsa) Hs9506543
(MOSPD1)
GI:9506543 Q9UJG1
Saccharomyces cerevisiae (Sce) YER120w
(S000000922)
GI:6320966 P40075
Schizosaccharomyces pombe (Spo) SPAC17C9.12 GI:19115506 Q10484
Schizosaccharomyces pombe (Spo) SPBC16G5.05c GI:19113546 O60119
Encephalitozoon cuniculi (Ecu) ECU11g0640 GI:19074864 Q8SQX9
Arabidopsis thaliana (Ath) At1g08820 GI:15223943
Arabidopsis thaliana (Ath) At1g51270 GI:15223792
Arabidopsis thaliana (Ath) At2g23830 GI:15224067
Arabidopsis thaliana (Ath) At2g23860 GI:15224069
Arabidopsis thaliana (Ath) At2g45140 GI:15225415
Arabidopsis thaliana (Ath) At3g60600 GI:11288305
Arabidopsis thaliana (Ath) At4g00170_1 GI:7486542
Arabidopsis thaliana (Ath) At4g05060 GI:5732080
Arabidopsis thaliana (Ath) At4g21450 GI:7485721
Arabidopsis thaliana (Ath) At5g47180 GI:15238034
Arabidopsis thaliana (Ath) At5g54110 GI:8809582
Caenorhabditis elegans (Cel) CE00465_1 GI:17557067
Caenorhabditis elegans (Cel) CE01966
(WBGene00018840)
GI:17534407 P91330
Caenorhabditis elegans (Cel) CE02532
(WBGene00016406)
GI:17550790 Q18438
Caenorhabditis elegans (Cel) CE02813
(WBGene00019410)
GI:17534907 Q21246
Caenorhabditis elegans (Cel) CE03695
(WBGene00011911)
GI:17542484 Q22660
Caenorhabditis elegans (Cel) CE08096
(WBGene00015696)
GI:17505564 P91035
Caenorhabditis elegans (Cel) CE08178 GI:17558002
Caenorhabditis elegans (Cel) CE09902
(WBGene00018008)
GI:17507123 O44782
Caenorhabditis elegans (Cel) CE10068
(WBGene00009550)
GI:17540302
Caenorhabditis elegans (Cel) CE10314_1 GI:17533927 O17099
Caenorhabditis elegans (Cel) CE15068
(WBGene00022546)
GI:17566602 O01630
Caenorhabditis elegans (Cel) CE15322
(WBGene00022708)
GI:17544558 P91567
Caenorhabditis elegans (Cel) CE16148
(WBGene00010184)
GI:17561532 O45592
Caenorhabditis elegans (Cel) CE16345
(WBGene00011478)
GI:17554934 O45751
Caenorhabditis elegans (Cel) CE24750
(WBGene00022833)
GI:17511135 Q9N4M2
Caenorhabditis elegans (Cel) CE25398 GI:17537467
Caenorhabditis elegans (Cel) CE29541_2 GI:17551830
Drosophila melanogaster (Dme) 7290454
(FBgn0029687)
GI:18543325 Q9W4N8
Drosophila melanogaster (Dme) 7295165 GI:7295165
Drosophila melanogaster (Dme) 7295411 GI:7295411
Homo sapiens (Hsa) Hs13122608 GI:13122608 O75425
Homo sapiens (Hsa) Hs17456917 GI:17456917
Homo sapiens (Hsa) Hs20070156 GI:20070156
Homo sapiens (Hsa) Hs4759302
(VAPB)
GI:4759302 O95292
Homo sapiens (Hsa) Hs9506543
(MOSPD1)
GI:9506543 Q9UJG1
Saccharomyces cerevisiae (Sce) YER120w
(S000000922)
GI:6320966 P40075
Schizosaccharomyces pombe (Spo) SPAC17C9.12 GI:19115506 Q10484
Schizosaccharomyces pombe (Spo) SPBC16G5.05c GI:19113546 O60119
Encephalitozoon cuniculi (Ecu) ECU11g0640 GI:19074864 Q8SQX9
Arabidopsis thaliana (Ath) At1g08820 GI:15223943
Arabidopsis thaliana (Ath) At1g51270 GI:15223792
Arabidopsis thaliana (Ath) At2g23830 GI:15224067
Arabidopsis thaliana (Ath) At2g23860 GI:15224069
Arabidopsis thaliana (Ath) At2g45140 GI:15225415
Arabidopsis thaliana (Ath) At3g60600 GI:11288305
Arabidopsis thaliana (Ath) At4g00170_1 GI:7486542
Arabidopsis thaliana (Ath) At4g05060 GI:5732080
Arabidopsis thaliana (Ath) At4g21450 GI:7485721
Arabidopsis thaliana (Ath) At5g47180 GI:15238034
Arabidopsis thaliana (Ath) At5g54110 GI:8809582
Caenorhabditis elegans (Cel) CE00465_1 GI:17557067
Caenorhabditis elegans (Cel) CE01966
(WBGene00018840)
GI:17534407 P91330
Caenorhabditis elegans (Cel) CE02532
(WBGene00016406)
GI:17550790 Q18438
Caenorhabditis elegans (Cel) CE02813
(WBGene00019410)
GI:17534907 Q21246
Caenorhabditis elegans (Cel) CE03695
(WBGene00011911)
GI:17542484 Q22660
Caenorhabditis elegans (Cel) CE08096
(WBGene00015696)
GI:17505564 P91035
Caenorhabditis elegans (Cel) CE08178 GI:17558002
Caenorhabditis elegans (Cel) CE09902
(WBGene00018008)
GI:17507123 O44782
Caenorhabditis elegans (Cel) CE10068
(WBGene00009550)
GI:17540302
Caenorhabditis elegans (Cel) CE10314_1 GI:17533927 O17099
Caenorhabditis elegans (Cel) CE15068
(WBGene00022546)
GI:17566602 O01630
Caenorhabditis elegans (Cel) CE15322
(WBGene00022708)
GI:17544558 P91567
Caenorhabditis elegans (Cel) CE16148
(WBGene00010184)
GI:17561532 O45592
Caenorhabditis elegans (Cel) CE16345
(WBGene00011478)
GI:17554934 O45751
Caenorhabditis elegans (Cel) CE24750
(WBGene00022833)
GI:17511135 Q9N4M2
Caenorhabditis elegans (Cel) CE25398 GI:17537467
Caenorhabditis elegans (Cel) CE29541_2 GI:17551830
Drosophila melanogaster (Dme) 7290454
(FBgn0029687)
GI:18543325 Q9W4N8
Drosophila melanogaster (Dme) 7295165 GI:7295165
Drosophila melanogaster (Dme) 7295411 GI:7295411
Homo sapiens (Hsa) Hs13122608 GI:13122608 O75425
Homo sapiens (Hsa) Hs17456917 GI:17456917
Homo sapiens (Hsa) Hs20070156 GI:20070156
Homo sapiens (Hsa) Hs4759302
(VAPB)
GI:4759302 O95292
Homo sapiens (Hsa) Hs9506543
(MOSPD1)
GI:9506543 Q9UJG1
Saccharomyces cerevisiae (Sce) YER120w
(S000000922)
GI:6320966 P40075
Schizosaccharomyces pombe (Spo) SPAC17C9.12 GI:19115506 Q10484
Schizosaccharomyces pombe (Spo) SPBC16G5.05c GI:19113546 O60119
Encephalitozoon cuniculi (Ecu) ECU11g0640 GI:19074864 Q8SQX9


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000326 protein storage vacuole C
IDA
AthAt3g60600
GO:0005575 cellular_component C
ND
AthAt2g23830
At4g00170
GO:0005634 nucleus C
IDA
AthAt2g45140
At3g60600
GO:0005635 nuclear envelope C
IDA
SceS000000922
GO:0005783 endoplasmic reticulum C
IDA
AthAt2g45140
At3g60600
HsaVAPB
SceS000000922
SpoSPBC16G5.05c
ISS
SpoSPBC16G5.05c
GO:0005789 endoplasmic reticulum membrane C
EXP
HsaVAPB
IC
SpoSPBC16G5.05c
IDA
AthAt1g08820
At3g60600
HsaVAPB
ISS
SpoSPAC17C9.12
GO:0005794 Golgi apparatus C
IDA
HsaVAPB
GO:0005811 lipid particle C
IDA
DmeFBgn0029687
GO:0005829 cytosol C
IDA
AthAt2g45140
At3g60600
SpoSPAC17C9.12
GO:0005886 plasma membrane C
IDA
AthAt5g54110
At5g47180
At2g45140
At3g60600
At4g21450
At1g08820
GO:0005934 cellular bud tip C
IDA
SceS000000922
GO:0008021 synaptic vesicle C
NAS
DmeFBgn0029687
GO:0016021 integral to membrane C
IDA
AthAt3g60600
ISS
SpoSPBC16G5.05c
GO:0030176 integral to endoplasmic reticulum
membrane
C
IDA
SceS000000922
GO:0031965 nuclear membrane C
IDA
SceS000000922
GO:0003674 molecular_function F
ND
SpoSPBC16G5.05c
SPAC17C9.12
GO:0005198 structural molecule activity F
ISS
AthAt5g47180
At4g21450
At2g45140
At4g00170
At5g54110
At2g23830
At1g51270
At4g05060
GO:0005515 protein binding F
IPI
AthAt3g60600
HsaVAPB
GO:0019899 enzyme binding F
IPI
HsaVAPB
GO:0019904 protein domain specific binding F
IPI
CelWBGene00018008
GO:0033149 FFAT motif binding F
IMP
SceS000000922
IPI
SceS000000922
GO:0035091 phosphoinositide binding F
IDA
SceS000000922
GO:0042803 protein homodimerization activity F
IPI
HsaVAPB
GO:0046875 ephrin receptor binding F
IPI
CelWBGene00018008
GO:0046982 protein heterodimerization activity F
IPI
HsaVAPB
GO:0048487 beta-tubulin binding F
IDA
HsaVAPB
GO:0000003 reproduction P
IMP
CelWBGene00018840
WBGene00018008
GO:0002119 nematode larval development P
IMP
CelWBGene00018008
GO:0006020 inositol metabolic process P
ISS
SpoSPBC16G5.05c
SPAC17C9.12
GO:0006348 chromatin silencing at telomere P
IGI
SceS000000922
IMP
SceS000000922
GO:0006970 response to osmotic stress P
IEP
AthAt5g54110
GO:0006984 ER-nucleus signaling pathway P
RCA
SceS000000922
GO:0007269 neurotransmitter secretion P
NAS
DmeFBgn0029687
GO:0007528 neuromuscular junction development P
IMP
DmeFBgn0029687
GO:0008150 biological_process P
ND
AthAt2g23830
At4g05060
At4g00170
At4g21450
GO:0008654 phospholipid biosynthetic process P
IGI
SceS000000922
IMP
SceS000000922
GO:0009792 embryo development ending in birth or egg
hatching
P
IMP
CelWBGene00018008
GO:0016082 synaptic vesicle priming P
NAS
DmeFBgn0029687
GO:0019048 virus-host interaction P
IDA
HsaVAPB
GO:0019915 lipid storage P
IMP
CelWBGene00018840
GO:0030968 endoplasmic reticulum unfolded protein
response
P
IMP
HsaVAPB
GO:0032377 regulation of intracellular lipid
transport
P
IMP
SceS000000922
GO:0040039 inductive cell migration P
IMP
CelWBGene00018008
GO:0042992 negative regulation of transcription factor import
into nucleus
P
IMP
SceS000000922
IPI
SceS000000922
GO:0045047 protein targeting to ER P
ISS
SpoSPAC17C9.12
SPBC16G5.05c
GO:0045070 positive regulation of viral genome
replication
P
IMP
HsaVAPB
GO:0046907 intracellular transport P
TAS
AthAt1g08820
At3g60600
GO:0048309 endoplasmic reticulum inheritance P
IGI
SceS000000922
IMP
SceS000000922
GO:0051402 neuron apoptosis P
IMP
DmeFBgn0029687

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
117790

Species Gene ID NCBI link UniProt link
Schizosaccharomyces pombe (Spo) SPAC17C9.12 GI:19115506 Q10484
Saccharomyces cerevisiae (Sce) SCS2
(S000000922)
GI:6320966 P40075
Kluyveromyces lactis (Kla) KLLA0E06853g GI:50308511
Eremothecium gossypii (Ego) AGOS_AGL282W GI:45200815
Magnaporthe grisea (Mgr) MGG_06183 GI:145603230
Neurospora crassa (Ncr) NCU08956.1 GI:32421809