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Search term: YER144C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name UBP5
SGD link S000000946
Alternative ID YER144C
Description Putative ubiquitin-specific protease, closest paralog of Doa4p but has no functional overlap; concentrates at the bud neck
Synonyms YER144C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1868 ACDHYPE

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Ubiquitin C-terminal hydrolase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At4g39370 GI:5738367
Caenorhabditis elegans (Cel) CE26210
(WBGene00013342)		 GI:17566062
Drosophila melanogaster (Dme) 7295645 GI:7295645
Drosophila melanogaster (Dme) 7300711 GI:7300711
Homo sapiens (Hsa) Hs10190742
(USP29)		 GI:10190742 Q9HBJ7
Homo sapiens (Hsa) Hs13994268
(USP26)		 GI:13994268 Q9BXU7
Homo sapiens (Hsa) Hs17441694 GI:17441694
Homo sapiens (Hsa) Hs21265129 GI:21265129
Homo sapiens (Hsa) Hs21361712 GI:16552833 O75604
Homo sapiens (Hsa) Hs22045513 GI:22045513
Homo sapiens (Hsa) Hs22056581 GI:22056581
Homo sapiens (Hsa) Hs4827054 GI:4827054
Homo sapiens (Hsa) Hs6912742 GI:6912742
Homo sapiens (Hsa) HsM19923759 GI:15314773
Homo sapiens (Hsa) HsM7706755 GI:7706755
Saccharomyces cerevisiae (Sce) YDR069c
(S000002476)		 GI:6320274 P32571
Saccharomyces cerevisiae (Sce) YER144c
(S000000946)		 GI:6320992 P39944
Saccharomyces cerevisiae (Sce) YIL156w
(S000001418)		 GI:6322035 P40453
Saccharomyces cerevisiae (Sce) YKR098c
(S000001806)		 GI:6322951 P36026
Schizosaccharomyces pombe (Spo) SPBC18H10.08c GI:19112524 O60139
Encephalitozoon cuniculi (Ecu) ECU07g0410 GI:19074463 Q8SRL2


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000131 incipient cellular bud site C
IDA
SceS000000946
GO:0000502 proteasome complex C
IPI
SceS000002476
GO:0005575 cellular_component C
ND
HsaUSP29
SceS000001806
GO:0005624 membrane fraction C
IDA
SceS000002476
GO:0005634 nucleus C
IDA
HsaUSP26
GO:0005737 cytoplasm C
IC
SceS000001418
IDA
SpoSPBC18H10.08c
GO:0005739 mitochondrion C
IDA
SceS000002476
GO:0005768 endosome C
IDA
SceS000002476
GO:0005935 cellular bud neck C
IDA
SceS000000946
GO:0004175 endopeptidase activity F
IGI
SceS000002476
IPI
SceS000002476
GO:0004221 ubiquitin thiolesterase activity F
IDA
SceS000002476
IMP
SceS000002476
TAS
HsaUSP29
GO:0004843 ubiquitin-specific protease activity F
IDA
SceS000001806
S000002476
ISS
AthAt4g39370
TAS
SceS000000946
S000001418
GO:0005515 protein binding F
IPI
HsaUSP26
USP29
GO:0016741 transferase activity, transferring one-carbon
groups		 F
RCA
SceS000002476
GO:0006275 regulation of DNA replication P
IMP
SceS000002476
GO:0006464 protein modification process P
NAS
HsaUSP29
GO:0006508 proteolysis P
RCA
SceS000002476
GO:0006511 ubiquitin-dependent protein catabolic
process		 P
IMP
SceS000002476
GO:0006897 endocytosis P
IMP
SceS000002476
GO:0006914 autophagy P
RCA
SceS000002476
GO:0008150 biological_process P
ND
SceS000001806
GO:0010992 ubiquitin homeostasis P
IMP
SceS000002476
GO:0010995 free ubiquitin chain depolymerization P
IDA
SceS000002476
GO:0016579 protein deubiquitination P
IDA
HsaUSP26
TAS
SceS000001418
S000000946
S000002476
GO:0030435 sporulation resulting in formation of a cellular
spore		 P
RCA
SceS000002476
GO:0043162 ubiquitin-dependent protein catabolic process via
the multivesicular body sorting
pathway		 P
IMP
SceS000002476
GO:0045184 establishment of protein localization P
RCA
SceS000002476
GO:0051049 regulation of transport P
RCA
SceS000000946

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_40067

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Caenorhabditis elegans (Cel) cel20116 Y59A8B.2
(CE26210;
WBGene00013342)
Saccharomyces cerevisiae (Sce) sce1886 YER144C
(S000000946)


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000131 incipient cellular bud site C
IDA
SceS000000946
GO:0005935 cellular bud neck C
IDA
SceS000000946
GO:0004843 ubiquitin-specific protease activity F
TAS
SceS000000946
GO:0016579 protein deubiquitination P
TAS
SceS000000946
GO:0051049 regulation of transport P
RCA
SceS000000946

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC18H10.08c
(O60139)		 YER144C
(S000000946)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000131 incipient cellular bud site C
IDA
SceS000000946
GO:0005737 cytoplasm C
IDA
SpoSPBC18H10.08c
GO:0005935 cellular bud neck C
IDA
SceS000000946
GO:0004843 ubiquitin-specific protease activity F
TAS
SceS000000946
GO:0016579 protein deubiquitination P
TAS
SceS000000946
GO:0051049 regulation of transport P
RCA
SceS000000946

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s.khadayate@ucl.ac.uk