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Search term: YER154W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name OXA1
SGD link S000000956
Alternative ID YER154W
Description Mitochondrial inner membrane insertase, mediates the insertion of both mitochondrial- and nuclear-encoded proteins from the matrix into the inner membrane, interacts with mitochondrial ribosomes; conserved from bacteria to animals
Synonyms YER154W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

Search for gene by ID or name:

Query species:

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1239 ACDHYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALINGCELLULAR PROCESSES AND SIGNALING Inner membrane protein translocase involved in respiratory chain assembly

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g24490_2 GI:15221768
Arabidopsis thaliana (Ath) At1g65080 GI:15217841
Arabidopsis thaliana (Ath) At2g28800 GI:15226968
Arabidopsis thaliana (Ath) At2g46470 GI:15225991
Arabidopsis thaliana (Ath) At3g44360 GI:15229946
Arabidopsis thaliana (Ath) At3g44370 GI:15229959
Arabidopsis thaliana (Ath) At5g62050 GI:15241690
Caenorhabditis elegans (Cel) CE07785 GI:17505402
Caenorhabditis elegans (Cel) CE25492 GI:17543670
Drosophila melanogaster (Dme) 7294793 GI:7294793
Drosophila melanogaster (Dme) 7294995 GI:7294995
Homo sapiens (Hsa) Hs22043555 GI:22043555
Homo sapiens (Hsa) Hs4826880 GI:4826880
Saccharomyces cerevisiae (Sce) YER154w
(S000000956)		 GI:6321002 P39952
Saccharomyces cerevisiae (Sce) YGR062c
(S000003294)		 GI:6321499 P53239
Schizosaccharomyces pombe (Spo) SPAC9G1.04 GI:19114471 O14300
Schizosaccharomyces pombe (Spo) SPBC1346.02c GI:19112969
Schizosaccharomyces pombe (Spo) SPCC1442.15c GI:19075829 O94587
Arabidopsis thaliana (Ath) At1g24490_2 GI:15221768
Arabidopsis thaliana (Ath) At1g65080 GI:15217841
Arabidopsis thaliana (Ath) At2g28800 GI:15226968
Arabidopsis thaliana (Ath) At2g46470 GI:15225991
Arabidopsis thaliana (Ath) At3g44360 GI:15229946
Arabidopsis thaliana (Ath) At3g44370 GI:15229959
Arabidopsis thaliana (Ath) At5g62050 GI:15241690
Caenorhabditis elegans (Cel) CE07785 GI:17505402
Caenorhabditis elegans (Cel) CE25492 GI:17543670
Drosophila melanogaster (Dme) 7294793 GI:7294793
Drosophila melanogaster (Dme) 7294995 GI:7294995
Homo sapiens (Hsa) Hs22043555 GI:22043555
Homo sapiens (Hsa) Hs4826880 GI:4826880
Saccharomyces cerevisiae (Sce) YER154w
(S000000956)		 GI:6321002 P39952
Saccharomyces cerevisiae (Sce) YGR062c
(S000003294)		 GI:6321499 P53239
Schizosaccharomyces pombe (Spo) SPAC9G1.04 GI:19114471 O14300
Schizosaccharomyces pombe (Spo) SPBC1346.02c GI:19112969
Schizosaccharomyces pombe (Spo) SPCC1442.15c GI:19075829 O94587


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
AthAt5g62050
At3g44370
SceS000000956
SpoSPCC1442.15c
SPAC9G1.04
TAS
AthAt2g46470
GO:0005743 mitochondrial inner membrane C
IDA
AthAt5g62050
SceS000000956
TAS
SpoSPAC9G1.04
GO:0009507 chloroplast C
IDA
AthAt2g28800
GO:0009535 chloroplast thylakoid membrane C
IDA
AthAt2g28800
At1g24490
GO:0016020 membrane C
IDA
AthAt2g46470
ISS
AthAt1g65080
At1g24490
GO:0031305 integral to mitochondrial inner
membrane		 C
IDA
SceS000003294
IGI
SpoSPCC1442.15c
GO:0044455 mitochondrial membrane part C
RCA
SceS000000956
GO:0003674 molecular_function F
ND
AthAt2g46470
At1g24490
GO:0008565 protein transporter activity F
ISS
SpoSPAC9G1.04
GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane
transporter activity		 F
IDA
AthAt2g28800
IGI
AthAt5g62050
GO:0032977 membrane insertase activity F
IGI
SceS000003294
SpoSPCC1442.15c
IMP
SceS000003294
S000000956
IPI
SceS000003294
ISS
SceS000003294
GO:0043022 ribosome binding F
IDA
SceS000000956
GO:0006414 translational elongation P
RCA
SceS000003294
GO:0006461 protein complex assembly P
IMP
AthAt5g62050
GO:0006605 protein targeting P
RCA
SceS000000956
GO:0006886 intracellular protein transport P
RCA
SceS000000956
GO:0007165 signal transduction P
ISS
AthAt1g24490
GO:0008535 respiratory chain complex IV assembly P
IGI
SpoSPCC1442.15c
IMP
SpoSPAC9G1.04
GO:0009658 chloroplast organization P
IMP
AthAt1g24490
GO:0010027 thylakoid membrane organization P
IMP
AthAt2g28800
GO:0015031 protein transport P
IGI
SpoSPCC1442.15c
RCA
SceS000000956
GO:0032979 protein insertion into mitochondrial membrane from
inner side		 P
IGI
SceS000003294
IMP
SceS000000956
S000003294
IPI
SceS000003294
S000000956
GO:0033615 mitochondrial proton-transporting ATP synthase
complex assembly		 P
IMP
SceS000000956
GO:0045038 protein import into chloroplast thylakoid
membrane		 P
IDA
AthAt2g28800
GO:0045039 protein import into mitochondrial inner
membrane		 P
ISS
SpoSPAC9G1.04
TAS
AthAt2g46470
At5g62050
GO:0045184 establishment of protein localization P
RCA
SceS000000956
GO:0051204 protein insertion into mitochondrial
membrane		 P
IGI
SpoSPCC1442.15c
GO:0090342 regulation of cell aging P
IMP
AthAt2g28800

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
31281

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) OXA1L GI:223718097
Pan troglodytes (Ptr) OXA1L GI:114652024
Canis familiaris (Cfa) LOC480239 GI:57089985
Mus musculus (Mmu) Oxa1l
(MGI:1916339)		 GI:58037139 Q3TC56
Rattus norvegicus (Rno) Oxa1l GI:109501645
Drosophila melanogaster (Dme) CG6404
(FBgn0027615)		 GI:21356443
Anopheles gambiae (Aga) AgaP_AGAP005421 GI:158294169
Caenorhabditis elegans (Cel) C01A2.3
(CE38582;
WBGene00007215)		 GI:71980488
Saccharomyces cerevisiae (Sce) OXA1
(S000000956)		 GI:6321002 P39952
Kluyveromyces lactis (Kla) KLLA0E00891g GI:50307981
Eremothecium gossypii (Ego) AGOS_AGR143W GI:45201239
Arabidopsis thaliana (Ath) OXA1 GI:15241690
Arabidopsis thaliana (Ath) OXA1L GI:15225991
Oryza sativa (Osa) Os03g0116000 GI:115450311
Oryza sativa (Osa) Os10g0521300 GI:115482992


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
AthOXA1
HsaOXA1L
MmuMGI:1916339
SceS000000956
TAS
AthOXA1
GO:0005740 mitochondrial envelope C
ISS
DmeFBgn0027615
GO:0005743 mitochondrial inner membrane C
IDA
AthOXA1
MmuMGI:1916339
SceS000000956
ISS
DmeFBgn0027615
GO:0005746 mitochondrial respiratory chain C
NAS
HsaOXA1L
GO:0032592 integral to mitochondrial membrane C
IDA
HsaOXA1L
GO:0043234 protein complex C
IDA
HsaOXA1L
GO:0044455 mitochondrial membrane part C
RCA
SceS000000956
GO:0003674 molecular_function F
ND
AthOXA1
HsaOXA1L
MmuMGI:1916339
GO:0008565 protein transporter activity F
ISS
DmeFBgn0027615
GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane
transporter activity		 F
IGI
AthOXA1
GO:0032977 membrane insertase activity F
IMP
SceS000000956
GO:0043022 ribosome binding F
IDA
SceS000000956
GO:0002119 nematode larval development P
IMP
CelWBGene00007215
GO:0006461 protein complex assembly P
IMP
AthOXA1
NAS
HsaOXA1L
GO:0006605 protein targeting P
RCA
SceS000000956
GO:0006886 intracellular protein transport P
RCA
SceS000000956
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00007215
GO:0008150 biological_process P
ND
MmuMGI:1916339
GO:0008535 respiratory chain complex IV assembly P
ISS
DmeFBgn0027615
GO:0009060 aerobic respiration P
IMP
HsaOXA1L
NAS
HsaOXA1L
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00007215
GO:0015031 protein transport P
RCA
SceS000000956
GO:0032780 negative regulation of ATPase activity P
IMP
HsaOXA1L
GO:0032979 protein insertion into mitochondrial membrane from
inner side		 P
IMP
SceS000000956
IPI
SceS000000956
GO:0032981 mitochondrial respiratory chain complex I
assembly		 P
IMP
HsaOXA1L
GO:0033615 mitochondrial proton-transporting ATP synthase
complex assembly		 P
IMP
HsaOXA1L
SceS000000956
GO:0040007 growth P
IMP
CelWBGene00007215
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00007215
GO:0045039 protein import into mitochondrial inner
membrane		 P
TAS
AthOXA1
GO:0045184 establishment of protein localization P
RCA
SceS000000956
GO:0051354 negative regulation of oxidoreductase
activity		 P
IMP
HsaOXA1L
GO:0055114 oxidation reduction P
NAS
HsaOXA1L

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_3057

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga834 ENSANGP00000014070
Ashbya gossypii (Ago) ago4454 AGR143W
Arabidopsis thaliana (Ath) ath11886 At2g46470.1
Arabidopsis thaliana (Ath) ath28310 At5g62050.1
Caenorhabditis elegans (Cel) cel650 C01A2.3
(CE38582;
WBGene00007215)
Candida glabrata (Cgl) cgl2805 CAGL0I06534g
Cryptococcus neoformans (Cne) cne3380 167.m05900
Dictyostelium discoideum (Ddi) ddi9913 DDB0186234
Debaryomyces hansenii (Dha) dha239 DEHA0A05390g
Drosophila melanogaster (Dme) dme8964 CG6404-PA
(FBgn0027615)
Drosophila melanogaster (Dme) dme8965 CG6404-PB
(FBgn0027615)
Danio rerio (Dre) dre21118 ENSDARP00000017096
Takifugu rubripes (Fru) fru8848 SINFRUP00000161618
Homo sapiens (Hsa) hsa9218 ENSP00000285848
(OXA1L)		 Q2M1J6
Homo sapiens (Hsa) hsa9219 ENSP00000350740
(OXA1L)		 Q15070-2
Kluyveromyces lactis (Kla) kla2989 KLLA0E00891g
Mus musculus (Mmu) mmu8153 ENSMUSP00000000985
(MGI:1916339)		 Q8BGA9
Neurospora crassa (Ncr) ncr1066 NCU01102.2
Oryza sativa (Osa) osa322 37.m00126
Oryza sativa (Osa) osa40700 5191.m00120
Oryza sativa (Osa) osa61759 6605.m00134
Rattus norvegicus (Rno) rno11322 ENSRNOP00000013246
(RGD:1585024)
Saccharomyces cerevisiae (Sce) sce1900 YER154W
(S000000956)
Schizosaccharomyces pombe (Spo) spo975 SPAC9G1.04 O14300
Schizosaccharomyces pombe (Spo) spo4534 SPBP4H10.03 O43092
Yarrowia lipolytica (Yli) yli6661 YALI0F32021g