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Search term: YER169W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name RPH1
SGD link S000000971
Alternative ID YER169W
Description JmjC domain-containing histone demethylase which can specifically demethylate H3K36 tri- and dimethyl modification states; transcriptional repressor of PHR1; Rph1p phosphorylation during DNA damage is under control of the MEC1-RAD53 pathway
Synonyms YER169W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

HomoloGene results:

HomoloGene cluster Phylogenetic pattern
117793

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) RPH1
(S000000971)		 GI:6321017 P39956
Kluyveromyces lactis (Kla) KLLA0C17710g GI:50306059
Eremothecium gossypii (Ego) AGOS_AGR117C GI:45201213


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IC
SceS000000971
GO:0016566 specific transcriptional repressor
activity		 F
IDA
SceS000000971
GO:0032453 histone demethylase activity (H3-K4
specific)		 F
IMP
SceS000000971
GO:0032454 histone demethylase activity (H3-K9
specific)		 F
IDA
SceS000000971
IMP
SceS000000971
GO:0043565 sequence-specific DNA binding F
IDA
SceS000000971
GO:0051864 histone demethylase activity (H3-K36
specific)		 F
IDA
SceS000000971
IMP
SceS000000971
GO:0000122 negative regulation of transcription from RNA
polymerase II promoter		 P
IDA
SceS000000971
GO:0006281 DNA repair P
IMP
SceS000000971
GO:0016577 histone demethylation P
IDA
SceS000000971
IMP
SceS000000971

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_739

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga2223 ENSANGP00000020206
Anopheles gambiae (Aga) aga8217 ENSANGP00000021998
Ashbya gossypii (Ago) ago4428 AGR117C
Caenorhabditis elegans (Cel) cel19200 Y48B6A.11
(CE41181;
WBGene00012982)
Candida glabrata (Cgl) cgl4592 CAGL0L11880g
Debaryomyces hansenii (Dha) dha3980 DEHA0E16687g
Drosophila melanogaster (Dme) dme3764 CG15835-PA
(FBgn0033233)
Drosophila melanogaster (Dme) dme4847 CG33182-PA
(FBgn0053182)
Danio rerio (Dre) dre23733 ENSDARP00000024692
Danio rerio (Dre) dre23731 ENSDARP00000034460
Danio rerio (Dre) dre23734 ENSDARP00000034461
Danio rerio (Dre) dre23732 ENSDARP00000034954
Danio rerio (Dre) dre23730 ENSDARP00000035386
Takifugu rubripes (Fru) fru9499 SINFRUP00000147134
Takifugu rubripes (Fru) fru8948 SINFRUP00000151437
Takifugu rubripes (Fru) fru8949 SINFRUP00000151439
Takifugu rubripes (Fru) fru22042 SINFRUP00000161144
Takifugu rubripes (Fru) fru22039 SINFRUP00000161146
Takifugu rubripes (Fru) fru8947 SINFRUP00000167776
Takifugu rubripes (Fru) fru22041 SINFRUP00000167863
Takifugu rubripes (Fru) fru8950 SINFRUP00000168478
Takifugu rubripes (Fru) fru9500 SINFRUP00000171283
Takifugu rubripes (Fru) fru22040 SINFRUP00000175039
Takifugu rubripes (Fru) fru9501 SINFRUP00000176204
Gallus gallus (Gga) gga14229 ENSGALP00000006499
Gallus gallus (Gga) gga14230 ENSGALP00000006500
Gallus gallus (Gga) gga14227 ENSGALP00000006501
(JMJD2B)
Gallus gallus (Gga) gga14226 ENSGALP00000006502
Gallus gallus (Gga) gga14231 ENSGALP00000006503
Gallus gallus (Gga) gga14228 ENSGALP00000006504
Gallus gallus (Gga) gga22652 ENSGALP00000016355
Gallus gallus (Gga) gga22653 ENSGALP00000016356
Gallus gallus (Gga) gga22650 ENSGALP00000016357
(JMJD2A)
Gallus gallus (Gga) gga22651 ENSGALP00000016358
Homo sapiens (Hsa) hsa15394 ENSP00000159111
(KDM4B)		 O94953-1
Homo sapiens (Hsa) hsa31013 ENSP00000262356
Homo sapiens (Hsa) hsa1008 ENSP00000262914
Homo sapiens (Hsa) hsa6425 ENSP00000334181
(KDM4D)		 Q6B0I6
Kluyveromyces lactis (Kla) kla1990 KLLA0C17710g
Mus musculus (Mmu) mmu11943 ENSMUSP00000025036
(MGI:2442355)		 Q91VY5-1
Mus musculus (Mmu) mmu18324 ENSMUSP00000030102
(MGI:1924054)		 Q8VCD7
Mus musculus (Mmu) mmu18740 ENSMUSP00000040088
Mus musculus (Mmu) mmu27019 ENSMUSP00000050828
Mus musculus (Mmu) mmu18741 ENSMUSP00000062910
(MGI:2446210)		 A2A8L9
Mus musculus (Mmu) mmu18323 ENSMUSP00000077017
(MGI:1924054)		 Q8VCD7
Neurospora crassa (Ncr) ncr3397 NCU03505.2
Rattus norvegicus (Rno) rno23331 ENSRNOP00000008890
Rattus norvegicus (Rno) rno23329 ENSRNOP00000008916
Rattus norvegicus (Rno) rno23330 ENSRNOP00000009083 B0BNJ6
Rattus norvegicus (Rno) rno23768 ENSRNOP00000027049
(RGD:1306378)
Saccharomyces cerevisiae (Sce) sce1918 YER169W
(S000000971)
Yarrowia lipolytica (Yli) yli5953 YALI0F14487g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IC
SceS000000971
ISS
DmeFBgn0053182
FBgn0033233
GO:0016564 transcription repressor activity F
ISS
DmeFBgn0033233
FBgn0053182
GO:0016566 specific transcriptional repressor
activity		 F
IDA
SceS000000971
GO:0032453 histone demethylase activity (H3-K4
specific)		 F
IMP
SceS000000971
GO:0032454 histone demethylase activity (H3-K9
specific)		 F
IDA
DmeFBgn0053182
SceS000000971
IMP
DmeFBgn0033233
FBgn0053182
SceS000000971
GO:0043565 sequence-specific DNA binding F
IDA
SceS000000971
GO:0051864 histone demethylase activity (H3-K36
specific)		 F
IDA
DmeFBgn0053182
FBgn0033233
SceS000000971
IMP
DmeFBgn0053182
FBgn0033233
SceS000000971
ISS
DmeFBgn0053182
FBgn0033233
GO:0000122 negative regulation of transcription from RNA
polymerase II promoter		 P
IDA
SceS000000971
GO:0006281 DNA repair P
IMP
SceS000000971
GO:0016577 histone demethylation P
IDA
SceS000000971
IMP
SceS000000971
ISS
DmeFBgn0053182
FBgn0033233
GO:0033169 histone H3-K9 demethylation P
IDA
DmeFBgn0053182
IMP
DmeFBgn0053182
FBgn0033233
GO:0070544 histone H3-K36 demethylation P
IMP
DmeFBgn0053182
FBgn0033233

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC83.07
(O94691)		 YER169W
(S000000971)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000790 nuclear chromatin C
IC
SpoSPBC83.07
GO:0005634 nucleus C
IC
SceS000000971
IDA
SpoSPBC83.07
GO:0005829 cytosol C
IDA
SpoSPBC83.07
GO:0048189 Lid2 complex C
IDA
SpoSPBC83.07
GO:0016566 specific transcriptional repressor
activity		 F
IDA
SceS000000971
ISS
SpoSPBC83.07
GO:0032453 histone demethylase activity (H3-K4
specific)		 F
IMP
SceS000000971
GO:0032454 histone demethylase activity (H3-K9
specific)		 F
IDA
SceS000000971
IMP
SceS000000971
GO:0043565 sequence-specific DNA binding F
IDA
SceS000000971
GO:0051864 histone demethylase activity (H3-K36
specific)		 F
IDA
SceS000000971
IMP
SceS000000971
ISS
SpoSPBC83.07
GO:0000122 negative regulation of transcription from RNA
polymerase II promoter		 P
IDA
SceS000000971
GO:0006281 DNA repair P
IMP
SceS000000971
GO:0006338 chromatin remodeling P
IC
SpoSPBC83.07
GO:0006355 regulation of transcription, DNA-dependent P
IC
SpoSPBC83.07
GO:0016481 negative regulation of transcription P
ISS
SpoSPBC83.07
GO:0016577 histone demethylation P
IDA
SceS000000971
IMP
SceS000000971
ISS
SpoSPBC83.07
GO:0070544 histone H3-K36 demethylation P
ISS
SpoSPBC83.07

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