YOGY Home YOGY Help

Search term: YER172C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name BRR2
SGD link S000000974
Alternative ID YER172C
Description RNA-dependent ATPase RNA helicase (DEIH box); required for disruption of U4/U6 base-pairing in native snRNPs to activate the spliceosome for catalysis; homologous to human U5-200kD
Synonyms YER172C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0951 ACDHYPE

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING RNA helicase BRR2, DEAD-box superfamily

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g20960 GI:15218086
Arabidopsis thaliana (Ath) At1g79940_2 GI:15220027
Arabidopsis thaliana (Ath) At2g42270 GI:15227913
Arabidopsis thaliana (Ath) At3g28870_2 GI:15228509
Arabidopsis thaliana (Ath) At4g21180_2 GI:7486588
Caenorhabditis elegans (Cel) CE21971
(WBGene00012896)		 GI:17537127 Q9U2G0
Caenorhabditis elegans (Cel) CE24303 GI:17537131
Drosophila melanogaster (Dme) 7294212 GI:7294212
Homo sapiens (Hsa) Hs22042312 GI:22042312
Saccharomyces cerevisiae (Sce) YER172c
(S000000974)		 GI:6321020 P32639
Schizosaccharomyces pombe (Spo) SPAC9.03c GI:19114258 Q9UT24
Encephalitozoon cuniculi (Ecu) ECU06g0920 GI:19074342 Q8SRQ1
Arabidopsis thaliana (Ath) At1g20960 GI:15218086
Arabidopsis thaliana (Ath) At1g79940_2 GI:15220027
Arabidopsis thaliana (Ath) At2g42270 GI:15227913
Arabidopsis thaliana (Ath) At3g28870_2 GI:15228509
Arabidopsis thaliana (Ath) At4g21180_2 GI:7486588
Caenorhabditis elegans (Cel) CE21971
(WBGene00012896)		 GI:17537127 Q9U2G0
Caenorhabditis elegans (Cel) CE24303 GI:17537131
Drosophila melanogaster (Dme) 7294212 GI:7294212
Homo sapiens (Hsa) Hs22042312 GI:22042312
Saccharomyces cerevisiae (Sce) YER172c
(S000000974)		 GI:6321020 P32639
Schizosaccharomyces pombe (Spo) SPAC9.03c GI:19114258 Q9UT24
Encephalitozoon cuniculi (Ecu) ECU06g0920 GI:19074342 Q8SRQ1


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt3g28870
GO:0005634 nucleus C
IDA
SpoSPAC9.03c
GO:0005681 spliceosomal complex C
IDA
SpoSPAC9.03c
GO:0005682 U5 snRNP C
IDA
SceS000000974
ISS
SpoSPAC9.03c
GO:0005688 U6 snRNP C
RCA
SceS000000974
GO:0005730 nucleolus C
IDA
AthAt1g20960
GO:0005739 mitochondrion C
IDA
AthAt1g79940
GO:0005783 endoplasmic reticulum C
IDA
AthAt1g79940
At4g21180
GO:0005829 cytosol C
IDA
SpoSPAC9.03c
GO:0005886 plasma membrane C
IDA
AthAt1g79940
At4g21180
GO:0016020 membrane C
IDA
AthAt1g20960
GO:0030176 integral to endoplasmic reticulum
membrane		 C
IDA
AthAt4g21180
At1g79940
GO:0046540 U4/U6 x U5 tri-snRNP complex C
IDA
SceS000000974
ISS
SpoSPAC9.03c
GO:0003674 molecular_function F
ND
AthAt3g28870
GO:0004004 ATP-dependent RNA helicase activity F
IDA
SceS000000974
IMP
SceS000000974
ISS
SpoSPAC9.03c
GO:0008026 ATP-dependent helicase activity F
ISS
AthAt2g42270
At1g20960
GO:0000003 reproduction P
IMP
CelWBGene00012896
GO:0000388 spliceosome conformational change to release U4
(or U4atac) and U1 (or U11)		 P
IMP
SceS000000974
GO:0000393 spliceosomal conformational changes to generate
catalytic conformation		 P
IGI
SpoSPAC9.03c
GO:0002119 nematode larval development P
IMP
CelWBGene00012896
GO:0006200 ATP catabolic process P
ISS
SpoSPAC9.03c
GO:0006457 protein folding P
ISS
AthAt1g79940
At4g21180
GO:0008150 biological_process P
ND
AthAt3g28870
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00012896
GO:0009793 embryo development ending in seed
dormancy		 P
NAS
AthAt1g20960
GO:0016071 mRNA metabolic process P
RCA
SceS000000974
GO:0018991 oviposition P
IMP
CelWBGene00012896
GO:0040007 growth P
IMP
CelWBGene00012896

Back to the top

HomoloGene results:

HomoloGene cluster Phylogenetic pattern
5859

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) SNRNP200 GI:40217847
Pan troglodytes (Ptr) SNRNP200 GI:114578882
Canis familiaris (Cfa) SNRNP200 GI:73980225
Mus musculus (Mmu) Snrnp200
(MGI:2444401)		 GI:40018610 Q69ZZ3
Drosophila melanogaster (Dme) CG5931
(FBgn0036548)		 GI:28574898
Anopheles gambiae (Aga) AgaP_AGAP001519 GI:58396009
Caenorhabditis elegans (Cel) Y46G5A.4
(CE21971;
WBGene00012896)		 GI:17537127 Q9U2G0
Schizosaccharomyces pombe (Spo) brr2
(SPAC9.03c)		 GI:19114258 Q9UT24
Saccharomyces cerevisiae (Sce) BRR2
(S000000974)		 GI:6321020 P32639
Kluyveromyces lactis (Kla) KLLA0C17798g GI:50306067
Eremothecium gossypii (Ego) AGOS_AGR113W GI:45201209
Magnaporthe grisea (Mgr) MGG_11396 GI:145614658
Neurospora crassa (Ncr) NCU02685.1 GI:32422881
Arabidopsis thaliana (Ath) AT2G42270 GI:15227913
Arabidopsis thaliana (Ath) emb1507 GI:15218086
Plasmodium falciparum (Pfa) PFD1060w GI:124505573


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
MmuMGI:2444401
GO:0005634 nucleus C
IC
DmeFBgn0036548
IDA
SpoSPAC9.03c
GO:0005681 spliceosomal complex C
IDA
HsaSNRNP200
SpoSPAC9.03c
ISS
DmeFBgn0036548
PfaPFD1060w
GO:0005682 U5 snRNP C
IDA
HsaSNRNP200
SceS000000974
ISS
DmeFBgn0036548
SpoSPAC9.03c
GO:0005688 U6 snRNP C
RCA
SceS000000974
GO:0005730 nucleolus C
IDA
Athemb1507
GO:0005829 cytosol C
IDA
SpoSPAC9.03c
GO:0016020 membrane C
IDA
Athemb1507
GO:0030532 small nuclear ribonucleoprotein
complex		 C
ISS
DmeFBgn0036548
GO:0046540 U4/U6 x U5 tri-snRNP complex C
IDA
SceS000000974
ISS
SpoSPAC9.03c
GO:0071011 precatalytic spliceosome C
IDA
DmeFBgn0036548
GO:0071013 catalytic step 2 spliceosome C
IDA
DmeFBgn0036548
GO:0003674 molecular_function F
ND
MmuMGI:2444401
GO:0003724 RNA helicase activity F
ISS
DmeFBgn0036548
GO:0004004 ATP-dependent RNA helicase activity F
IDA
SceS000000974
IMP
SceS000000974
ISS
DmeFBgn0036548
PfaPFD1060w
SpoSPAC9.03c
GO:0005515 protein binding F
IPI
HsaSNRNP200
GO:0008026 ATP-dependent helicase activity F
IDA
HsaSNRNP200
ISS
AthAt2g42270
emb1507
GO:0000003 reproduction P
IMP
CelWBGene00012896
GO:0000354 cis assembly of pre-catalytic spliceosome P
IC
HsaSNRNP200
GO:0000381 regulation of alternative nuclear mRNA splicing,
via spliceosome		 P
IMP
DmeFBgn0036548
GO:0000388 spliceosome conformational change to release U4
(or U4atac) and U1 (or U11)		 P
IMP
SceS000000974
GO:0000393 spliceosomal conformational changes to generate
catalytic conformation		 P
IGI
SpoSPAC9.03c
GO:0000398 nuclear mRNA splicing, via spliceosome P
IC
DmeFBgn0036548
GO:0002119 nematode larval development P
IMP
CelWBGene00012896
GO:0006200 ATP catabolic process P
ISS
SpoSPAC9.03c
GO:0008150 biological_process P
ND
MmuMGI:2444401
GO:0008380 RNA splicing P
EXP
HsaSNRNP200
IDA
HsaSNRNP200
ISS
DmeFBgn0036548
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00012896
GO:0009793 embryo development ending in seed
dormancy		 P
NAS
Athemb1507
GO:0016071 mRNA metabolic process P
RCA
SceS000000974
GO:0018991 oviposition P
IMP
CelWBGene00012896
GO:0040007 growth P
IMP
CelWBGene00012896

Back to the top

OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_184

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga3615 ENSANGP00000009625
Anopheles gambiae (Aga) aga3309 ENSANGP00000013875
Ashbya gossypii (Ago) ago734 ABR142W
Ashbya gossypii (Ago) ago4424 AGR113W
Arabidopsis thaliana (Ath) ath2248 At1g20960.1
Arabidopsis thaliana (Ath) ath11401 At2g42270.1
Arabidopsis thaliana (Ath) ath28204 At5g61140.1
Caenorhabditis elegans (Cel) cel19021 Y46G5A.4
(CE21971;
WBGene00012896)
Caenorhabditis elegans (Cel) cel19731 Y54E2A.6
(CE20305;
WBGene00013191)
Candida glabrata (Cgl) cgl1648 CAGL0G00506g
Candida glabrata (Cgl) cgl4595 CAGL0L11946g
Cryptococcus neoformans (Cne) cne238 162.m02712
Cryptococcus neoformans (Cne) cne1263 180.m00204
Dictyostelium discoideum (Ddi) ddi8255 DDB0188864
Dictyostelium discoideum (Ddi) ddi1756 DDB0190760
Debaryomyces hansenii (Dha) dha6313 DEHA0G13761g
Debaryomyces hansenii (Dha) dha6668 DEHA0G21681g
Drosophila melanogaster (Dme) dme12782 CG5205-PA
(FBgn0038344)
Drosophila melanogaster (Dme) dme9687 CG5931-PA
(FBgn0036548)
Danio rerio (Dre) dre23544 ENSDARP00000011862
Danio rerio (Dre) dre23545 ENSDARP00000015906
Danio rerio (Dre) dre23543 ENSDARP00000041242
Encephalitozoon cuniculi (Ecu) ecu1569 19074342
Encephalitozoon cuniculi (Ecu) ecu1891 19074505
Takifugu rubripes (Fru) fru12328 SINFRUP00000131641
Takifugu rubripes (Fru) fru8033 SINFRUP00000160675
Takifugu rubripes (Fru) fru8032 SINFRUP00000160676
Takifugu rubripes (Fru) fru8031 SINFRUP00000160681
Takifugu rubripes (Fru) fru12330 SINFRUP00000165828
Takifugu rubripes (Fru) fru12329 SINFRUP00000166656
Takifugu rubripes (Fru) fru12331 SINFRUP00000172889
Takifugu rubripes (Fru) fru12327 SINFRUP00000173745
Gallus gallus (Gga) gga25148 ENSGALP00000005494
Gallus gallus (Gga) gga25149 ENSGALP00000005495
(ASCC3L1)		 Q5F463
Gallus gallus (Gga) gga26366 ENSGALP00000021714
Gallus gallus (Gga) gga15644 ENSGALP00000024888
Gallus gallus (Gga) gga15640 ENSGALP00000024889
(ASCC3)
Gallus gallus (Gga) gga15641 ENSGALP00000024890
Gallus gallus (Gga) gga15642 ENSGALP00000024891
Gallus gallus (Gga) gga15643 ENSGALP00000024892
Homo sapiens (Hsa) hsa27531 ENSP00000262902
Homo sapiens (Hsa) hsa18247 ENSP00000317123
(SNRNP200)		 O75643-1
Homo sapiens (Hsa) hsa27530 ENSP00000320252
(ASCC3)		 Q8N3C0
Homo sapiens (Hsa) hsa18248 ENSP00000326937
(SNRNP200)		 C9JAQ9
Kluyveromyces lactis (Kla) kla429 KLLA0A09889g
Kluyveromyces lactis (Kla) kla1994 KLLA0C17798g
Mus musculus (Mmu) mmu15445 ENSMUSP00000003757
Mus musculus (Mmu) mmu2116 ENSMUSP00000036726
(MGI:1925237)		 Q6PB36
Mus musculus (Mmu) mmu15446 ENSMUSP00000061054
(MGI:2444401)		 Q8BYH6
Neurospora crassa (Ncr) ncr2601 NCU02685.2
Neurospora crassa (Ncr) ncr8056 NCU08267.2
Oryza sativa (Osa) osa25259 3841.m00149
Oryza sativa (Osa) osa28710 4254.m00131
Oryza sativa (Osa) osa65026 6725.m00128
Oryza sativa (Osa) osa73926 7283.m00098
Plasmodium falciparum (Pfa) pfa1821 PF14_0370
Plasmodium falciparum (Pfa) pfa3301 PFD1060w
Rattus norvegicus (Rno) rno19655 ENSRNOP00000016835
(RGD:1561120)
Rattus norvegicus (Rno) rno19654 ENSRNOP00000048598
(RGD:1561120)		 Q4KLH1
Saccharomyces cerevisiae (Sce) sce1921 YER172C
(S000000974)
Saccharomyces cerevisiae (Sce) sce2655 YGR271W
(S000003503)
Schizosaccharomyces pombe (Spo) spo3123 SPAC9.03c Q9UT24
Schizosaccharomyces pombe (Spo) spo2636 SPBC13G1.10c O60072
Yarrowia lipolytica (Yli) yli1312 YALI0B13904g
Yarrowia lipolytica (Yli) yli6214 YALI0F20724g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
MmuMGI:1925237
MGI:2444401
PfaPF14_0370
GO:0005634 nucleus C
IC
DmeFBgn0036548
IDA
SpoSPAC9.03c
GO:0005681 spliceosomal complex C
IDA
SpoSPAC9.03c
ISS
DmeFBgn0036548
PfaPFD1060w
GO:0005682 U5 snRNP C
IDA
SceS000000974
ISS
DmeFBgn0036548
FBgn0038344
SpoSPAC9.03c
GO:0005688 U6 snRNP C
RCA
SceS000000974
GO:0005730 nucleolus C
IDA
AthAt1g20960
GO:0005737 cytoplasm C
IDA
SceS000003503
ISS
SpoSPBC13G1.10c
GO:0005829 cytosol C
IDA
SpoSPAC9.03c
SPBC13G1.10c
GO:0016020 membrane C
IDA
AthAt1g20960
GO:0030532 small nuclear ribonucleoprotein
complex		 C
ISS
DmeFBgn0036548
FBgn0038344
GO:0046540 U4/U6 x U5 tri-snRNP complex C
IDA
SceS000000974
ISS
SpoSPAC9.03c
GO:0071011 precatalytic spliceosome C
IDA
DmeFBgn0036548
GO:0071013 catalytic step 2 spliceosome C
IDA
DmeFBgn0036548
GO:0003674 molecular_function F
ND
MmuMGI:2444401
MGI:1925237
GO:0003724 RNA helicase activity F
ISS
DmeFBgn0036548
FBgn0038344
SceS000003503
GO:0004004 ATP-dependent RNA helicase activity F
IDA
SceS000000974
IMP
SceS000000974
ISS
DmeFBgn0036548
PfaPFD1060w
PF14_0370
SpoSPAC9.03c
SPBC13G1.10c
GO:0004386 helicase activity F
ISS
DmeFBgn0038344
GO:0008026 ATP-dependent helicase activity F
ISS
AthAt2g42270
At1g20960
At5g61140
GO:0000003 reproduction P
IMP
CelWBGene00012896
GO:0000381 regulation of alternative nuclear mRNA splicing,
via spliceosome		 P
IMP
DmeFBgn0036548
GO:0000388 spliceosome conformational change to release U4
(or U4atac) and U1 (or U11)		 P
IMP
SceS000000974
GO:0000393 spliceosomal conformational changes to generate
catalytic conformation		 P
IGI
SpoSPAC9.03c
GO:0000398 nuclear mRNA splicing, via spliceosome P
IC
DmeFBgn0036548
ISS
DmeFBgn0038344
GO:0002119 nematode larval development P
IMP
CelWBGene00012896
GO:0006200 ATP catabolic process P
ISS
SpoSPAC9.03c
GO:0006417 regulation of translation P
IGI
SceS000003503
IMP
SceS000003503
ISS
SpoSPBC13G1.10c
GO:0008150 biological_process P
ND
MmuMGI:2444401
MGI:1925237
PfaPF14_0370
GO:0008380 RNA splicing P
ISS
DmeFBgn0036548
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00012896
GO:0009793 embryo development ending in seed
dormancy		 P
NAS
AthAt1g20960
GO:0016071 mRNA metabolic process P
RCA
SceS000000974
GO:0018991 oviposition P
IMP
CelWBGene00012896
GO:0040007 growth P
IMP
CelWBGene00012896

Back to the top

Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC9.03c
(Q9UT24)		 YER172C
(S000000974)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPAC9.03c
GO:0005681 spliceosomal complex C
IDA
SpoSPAC9.03c
GO:0005682 U5 snRNP C
IDA
SceS000000974
ISS
SpoSPAC9.03c
GO:0005688 U6 snRNP C
RCA
SceS000000974
GO:0005829 cytosol C
IDA
SpoSPAC9.03c
GO:0046540 U4/U6 x U5 tri-snRNP complex C
IDA
SceS000000974
ISS
SpoSPAC9.03c
GO:0004004 ATP-dependent RNA helicase activity F
IDA
SceS000000974
IMP
SceS000000974
ISS
SpoSPAC9.03c
GO:0000388 spliceosome conformational change to release U4
(or U4atac) and U1 (or U11)		 P
IMP
SceS000000974
GO:0000393 spliceosomal conformational changes to generate
catalytic conformation		 P
IGI
SpoSPAC9.03c
GO:0006200 ATP catabolic process P
ISS
SpoSPAC9.03c
GO:0016071 mRNA metabolic process P
RCA
SceS000000974

Back to the top
YOGY Home YOGY Help

Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:

s.khadayate@ucl.ac.uk