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Search term: YER173W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name RAD24
SGD link S000000975
Alternative ID YER173W
Description Checkpoint protein, involved in the activation of the DNA damage and meiotic pachytene checkpoints; subunit of a clamp loader that loads Rad17p-Mec3p-Ddc1p onto DNA; homolog of human and S. pombe Rad17 protein
Synonyms YER173W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1970 ACDHYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALINGINFORMATION STORAGE AND PROCESSING Checkpoint RAD17-RFC complex, RAD17/RAD24 component

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At5g66130 GI:15239269
Caenorhabditis elegans (Cel) CE17738
(WBGene00001998)		 GI:17534769 O62196
Drosophila melanogaster (Dme) 7299911 GI:4019207
Homo sapiens (Hsa) Hs19718786
(RAD17)		 GI:19718786 O75943
Homo sapiens (Hsa) Hs19718788 GI:19718788 O75943
Homo sapiens (Hsa) Hs19718790 GI:19718790 O75943
Homo sapiens (Hsa) Hs4506383 GI:4506383 O75943
Saccharomyces cerevisiae (Sce) YER173w
(S000000975)		 GI:6321021 P32641
Schizosaccharomyces pombe (Spo) SPAC14C4.13 GI:19115830 P50531


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000781 chromosome, telomeric region C
IDA
HsaRAD17
GO:0000790 nuclear chromatin C
IC
SpoSPAC14C4.13
GO:0005634 nucleus C
IDA
HsaRAD17
IPI
SceS000000975
GO:0005737 cytoplasm C
IDA
HsaRAD17
GO:0031389 Rad17 RFC-like complex C
IDA
SceS000000975
TAS
SpoSPAC14C4.13
GO:0003689 DNA clamp loader activity F
IDA
SceS000000975
TAS
SpoSPAC14C4.13
GO:0005515 protein binding F
IPI
HsaRAD17
GO:0005524 ATP binding F
ISS
SpoSPAC14C4.13
GO:0000076 DNA replication checkpoint P
IMP
SpoSPAC14C4.13
TAS
HsaRAD17
GO:0000077 DNA damage checkpoint P
IMP
HsaRAD17
SceS000000975
SpoSPAC14C4.13
GO:0006260 DNA replication P
EXP
HsaRAD17
RCA
SceS000000975
GO:0006281 DNA repair P
RCA
SceS000000975
GO:0006282 regulation of DNA repair P
IMP
AthAt5g66130
GO:0006289 nucleotide-excision repair P
IMP
SceS000000975
GO:0006974 response to DNA damage stimulus P
IMP
CelWBGene00001998
HsaRAD17
RCA
SceS000000975
GO:0007049 cell cycle P
IMP
CelWBGene00001998
GO:0007093 mitotic cell cycle checkpoint P
IMP
HsaRAD17
GO:0007131 reciprocal meiotic recombination P
IMP
SceS000000975
GO:0007346 regulation of mitotic cell cycle P
NAS
SpoSPAC14C4.13
GO:0008156 negative regulation of DNA replication P
IMP
HsaRAD17
GO:0031573 intra-S DNA damage checkpoint P
IMP
SpoSPAC14C4.13
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00001998
GO:0042325 regulation of phosphorylation P
IMP
HsaRAD17
GO:0051052 regulation of DNA metabolic process P
RCA
SceS000000975
GO:0051321 meiotic cell cycle P
RCA
SceS000000975

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
38969

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) RAD24
(S000000975)		 GI:6321021 P32641
Kluyveromyces lactis (Kla) KLLA0C17820g GI:50306069
Eremothecium gossypii (Ego) AGOS_AGR112C GI:45201208


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IPI
SceS000000975
GO:0031389 Rad17 RFC-like complex C
IDA
SceS000000975
GO:0003689 DNA clamp loader activity F
IDA
SceS000000975
GO:0000077 DNA damage checkpoint P
IMP
SceS000000975
GO:0006260 DNA replication P
RCA
SceS000000975
GO:0006281 DNA repair P
RCA
SceS000000975
GO:0006289 nucleotide-excision repair P
IMP
SceS000000975
GO:0006974 response to DNA damage stimulus P
RCA
SceS000000975
GO:0007131 reciprocal meiotic recombination P
IMP
SceS000000975
GO:0051052 regulation of DNA metabolic process P
RCA
SceS000000975
GO:0051321 meiotic cell cycle P
RCA
SceS000000975

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1860

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga10698 ENSANGP00000005091
Ashbya gossypii (Ago) ago4423 AGR112C
Arabidopsis thaliana (Ath) ath28782 At5g66130.1
Caenorhabditis elegans (Cel) cel7833 F32A11.2
(CE17738;
WBGene00001998)
Candida glabrata (Cgl) cgl4596 CAGL0L11968g
Cryptococcus neoformans (Cne) cne4948 186.m03858
Dictyostelium discoideum (Ddi) ddi10828 DDB0184439
Dictyostelium discoideum (Ddi) ddi6021 DDB0206390
Debaryomyces hansenii (Dha) dha3979 DEHA0E16676g
Drosophila melanogaster (Dme) dme12616 CG7825-PA
(FBgn0025808)
Danio rerio (Dre) dre19107 ENSDARP00000014749
(zgc:91969)		 Q6DG57
Encephalitozoon cuniculi (Ecu) ecu1768 19075131
Takifugu rubripes (Fru) fru11341 SINFRUP00000177066
Gallus gallus (Gga) gga27987 ENSGALP00000025058
(RAD17)		 Q76F78
Homo sapiens (Hsa) hsa25328 ENSP00000282891
(RAD17)		 O75943-4
Homo sapiens (Hsa) hsa25333 ENSP00000303134
(RAD17)		 O75943-2
Homo sapiens (Hsa) hsa25329 ENSP00000311227
(RAD17)		 O75943-2
Homo sapiens (Hsa) hsa25334 ENSP00000324164
Homo sapiens (Hsa) hsa25331 ENSP00000346271
(RAD17)		 O75943-2
Homo sapiens (Hsa) hsa25332 ENSP00000346938
(RAD17)		 O75943-2
Homo sapiens (Hsa) hsa25330 ENSP00000350725
(RAD17)		 O75943-3
Homo sapiens (Hsa) hsa25327 ENSP00000355226
(RAD17)		 O75943-2
Kluyveromyces lactis (Kla) kla1995 KLLA0C17820g
Mus musculus (Mmu) mmu7469 ENSMUSP00000022136
(MGI:1333807)		 Q6NXW6
Neurospora crassa (Ncr) ncr503 NCU00517.2
Oryza sativa (Osa) osa56779 6394.m00128
Oryza sativa (Osa) osa69392 7076.m00099
Rattus norvegicus (Rno) rno15436 ENSRNOP00000024801
(RGD:1309515)		 Q4V7A2
Saccharomyces cerevisiae (Sce) sce1923 YER173W
(S000000975)
Schizosaccharomyces pombe (Spo) spo203 SPAC14C4.13 P50531
Yarrowia lipolytica (Yli) yli1290 YALI0B13376g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000790 nuclear chromatin C
IC
SpoSPAC14C4.13
GO:0005634 nucleus C
IPI
SceS000000975
GO:0031389 Rad17 RFC-like complex C
IDA
SceS000000975
TAS
SpoSPAC14C4.13
GO:0003689 DNA clamp loader activity F
IDA
SceS000000975
TAS
SpoSPAC14C4.13
GO:0005524 ATP binding F
ISS
SpoSPAC14C4.13
GO:0000076 DNA replication checkpoint P
IMP
SpoSPAC14C4.13
GO:0000077 DNA damage checkpoint P
IMP
SceS000000975
SpoSPAC14C4.13
GO:0006260 DNA replication P
RCA
SceS000000975
GO:0006281 DNA repair P
ISS
DmeFBgn0025808
NAS
DmeFBgn0025808
RCA
SceS000000975
GO:0006282 regulation of DNA repair P
IMP
AthAt5g66130
GO:0006289 nucleotide-excision repair P
IMP
SceS000000975
GO:0006974 response to DNA damage stimulus P
IMP
CelWBGene00001998
MmuMGI:1333807
RCA
SceS000000975
GO:0007049 cell cycle P
IMP
CelWBGene00001998
GO:0007131 reciprocal meiotic recombination P
IMP
SceS000000975
GO:0007346 regulation of mitotic cell cycle P
NAS
SpoSPAC14C4.13
GO:0031573 intra-S DNA damage checkpoint P
IMP
SpoSPAC14C4.13
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00001998
GO:0051052 regulation of DNA metabolic process P
RCA
SceS000000975
GO:0051321 meiotic cell cycle P
RCA
SceS000000975

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC14C4.13
(P50531)		 YER173W
(S000000975)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000790 nuclear chromatin C
IC
SpoSPAC14C4.13
GO:0005634 nucleus C
IPI
SceS000000975
GO:0031389 Rad17 RFC-like complex C
IDA
SceS000000975
TAS
SpoSPAC14C4.13
GO:0003689 DNA clamp loader activity F
IDA
SceS000000975
TAS
SpoSPAC14C4.13
GO:0005524 ATP binding F
ISS
SpoSPAC14C4.13
GO:0000076 DNA replication checkpoint P
IMP
SpoSPAC14C4.13
GO:0000077 DNA damage checkpoint P
IMP
SceS000000975
SpoSPAC14C4.13
GO:0006260 DNA replication P
RCA
SceS000000975
GO:0006281 DNA repair P
RCA
SceS000000975
GO:0006289 nucleotide-excision repair P
IMP
SceS000000975
GO:0006974 response to DNA damage stimulus P
RCA
SceS000000975
GO:0007131 reciprocal meiotic recombination P
IMP
SceS000000975
GO:0007346 regulation of mitotic cell cycle P
NAS
SpoSPAC14C4.13
GO:0031573 intra-S DNA damage checkpoint P
IMP
SpoSPAC14C4.13
GO:0051052 regulation of DNA metabolic process P
RCA
SceS000000975
GO:0051321 meiotic cell cycle P
RCA
SceS000000975

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GO info in one table:

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