Search term: YER176W

Gene summary:

KOG results:

KOG name	Phylogenetic pattern (and link to KOGs with this pattern)
KOG1802	ACDHYPE

KOGs classification	KOGs description
INFORMATION STORAGE AND PROCESSING	RNA helicase nonsense mRNA reducing factor (pNORF1)

Species	KOG link	NCBI link	UniProt link
Arabidopsis thaliana (Ath)	At5g47010	GI:15237996
Caenorhabditis elegans (Cel)	CE28367 (WBGene00004880)	GI:17510163	O76512
Drosophila melanogaster (Dme)	7292718	GI:18203558
Homo sapiens (Hsa)	Hs18375673 (UPF1)	GI:18375673	O60385
Homo sapiens (Hsa)	Hs20162560	GI:20162560
Saccharomyces cerevisiae (Sce)	YER176w (S000000978)	GI:6321024	P32644
Saccharomyces cerevisiae (Sce)	YMR080c (S000004685)	GI:6323726	P30771
Schizosaccharomyces pombe (Spo)	SPAC16C9.06c	GI:19113992	Q09820
Encephalitozoon cuniculi (Ecu)	ECU10g1640	GI:19074775	Q8SR02

GO terms for KOG results:

GO ID	GO term	GO aspect	Evidence codes and associations
GO:0000785	chromatin	C	IDA Hsa UPF1
GO:0005634	nucleus	C	IDA Cel WBGene00004880
GO:0005737	cytoplasm	C	IDA Cel WBGene00004880 Sce S000004685 ISS Spo SPAC16C9.06c NAS Hsa UPF1 TAS Cel WBGene00004880
GO:0005829	cytosol	C	IDA Spo SPAC16C9.06c
GO:0005844	polysome	C	IDA Sce S000000978 TAS Sce S000004685
GO:0005886	plasma membrane	C	IDA Ath At5g47010
GO:0003676	nucleic acid binding	F	TAS Sce S000004685
GO:0003678	DNA helicase activity	F	IDA Sce S000000978
GO:0003682	chromatin binding	F	IDA Hsa UPF1
GO:0003723	RNA binding	F	NAS Hsa UPF1
GO:0003724	RNA helicase activity	F	ISS Ath At5g47010 Sce S000000978
GO:0004004	ATP-dependent RNA helicase activity	F	IDA Hsa UPF1 ISS Cel WBGene00004880 Spo SPAC16C9.06c TAS Sce S000004685
GO:0004386	helicase activity	F	NAS Hsa UPF1
GO:0005515	protein binding	F	IPI Cel WBGene00004880 Hsa UPF1
GO:0005524	ATP binding	F	IC Spo SPAC16C9.06c
GO:0008186	RNA-dependent ATPase activity	F	TAS Sce S000004685
GO:0051721	protein phosphatase 2A binding	F	IPI Cel WBGene00004880
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	P	IDA Hsa UPF1 IGI Cel WBGene00004880 IMP Hsa UPF1 ISS Spo SPAC16C9.06c NAS Hsa UPF1 TAS Hsa UPF1 Sce S000004685
GO:0000956	nuclear-transcribed mRNA catabolic process	P	IMP Sce S000004685
GO:0006260	DNA replication	P	IMP Hsa UPF1
GO:0006281	DNA repair	P	IDA Hsa UPF1
GO:0006406	mRNA export from nucleus	P	TAS Hsa UPF1
GO:0006415	translational termination	P	ISS Spo SPAC16C9.06c RCA Sce S000004685
GO:0006417	regulation of translation	P	RCA Sce S000004685
GO:0006449	regulation of translational termination	P	IMP Hsa UPF1 Sce S000000978 NAS Hsa UPF1 TAS Sce S000004685
GO:0006605	protein targeting	P	RCA Sce S000004685
GO:0006886	intracellular protein transport	P	RCA Sce S000004685
GO:0007049	cell cycle	P	IMP Hsa UPF1
GO:0008298	intracellular mRNA localization	P	IMP Sce S000004685
GO:0009744	response to sucrose stimulus	P	IGI Ath At5g47010
GO:0010182	sugar mediated signaling pathway	P	IMP Ath At5g47010
GO:0015031	protein transport	P	RCA Sce S000004685
GO:0016246	RNA interference	P	IGI Ath At5g47010 IMP Cel WBGene00004880
GO:0016567	protein ubiquitination	P	IDA Sce S000004685 IMP Sce S000004685 IPI Sce S000004685
GO:0030466	chromatin silencing at silent mating-type cassette	P	IGI Sce S000004685
GO:0030538	embryonic genitalia morphogenesis	P	IMP Cel WBGene00004880
GO:0034613	cellular protein localization	P	RCA Sce S000004685
GO:0040035	hermaphrodite genitalia development	P	IMP Cel WBGene00004880
GO:0045184	establishment of protein localization	P	RCA Sce S000004685
GO:0070478	nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay	P	IGI Sce S000004685 IMP Sce S000004685
GO:0071044	histone mRNA catabolic process	P	IMP Hsa UPF1

HomoloGene results:

HomoloGene cluster	Phylogenetic pattern
74666

Species	Gene ID	NCBI link	UniProt link
Saccharomyces cerevisiae (Sce)	ECM32 (S000000978)	GI:6321024	P32644
Eremothecium gossypii (Ego)	AGOS_AGR108C	GI:45201204

GO terms for Homologene results:

GO ID	GO term	GO aspect	Evidence codes and associations
GO:0005844	polysome	C	IDA Sce S000000978
GO:0003678	DNA helicase activity	F	IDA Sce S000000978
GO:0003724	RNA helicase activity	F	ISS Sce S000000978
GO:0006449	regulation of translational termination	P	IMP Sce S000000978

OrthoMCL results:

OrthoMCL cluster	Phylogenetic pattern
OG1_31446

Species	OrthoMCL sequence	Model organism protein page	UniProt link
Ashbya gossypii (Ago)	ago4419	AGR108C
Candida glabrata (Cgl)	cgl4599	CAGL0L12034g
Debaryomyces hansenii (Dha)	dha4253	DEHA0E23034g
Saccharomyces cerevisiae (Sce)	sce1927	YER176W (S000000978)

GO terms for OrthoMCL results:

GO ID	GO term	GO aspect	Evidence codes and associations
GO:0005844	polysome	C	IDA Sce S000000978
GO:0003678	DNA helicase activity	F	IDA Sce S000000978
GO:0003724	RNA helicase activity	F	ISS Sce S000000978
GO:0006449	regulation of translational termination	P	IMP Sce S000000978