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Search term: YER179W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name DMC1
SGD link S000000981
Alternative ID YER179W
Description Meiosis-specific protein required for repair of double-strand breaks and pairing between homologous chromosomes; homolog of Rad51p and the bacterial RecA protein
Synonyms YER179W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1434 A--HYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALINGINFORMATION STORAGE AND PROCESSING Meiotic recombination protein Dmc1

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At2g45280 GI:15225444
Arabidopsis thaliana (Ath) At3g22880 GI:15228887
Homo sapiens (Hsa) Hs17402896
(RAD51C)		 GI:17402896 O43502
Homo sapiens (Hsa) Hs5901996 GI:5901996
Saccharomyces cerevisiae (Sce) YER179w
(S000000981)		 GI:6321027 P25453
Schizosaccharomyces pombe (Spo) SPAC8E11.03c GI:19115078 O42634


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000794 condensed nuclear chromosome C
IDA
SceS000000981
ISS
SpoSPAC8E11.03c
GO:0005575 cellular_component C
ND
AthAt2g45280
GO:0005634 nucleus C
IDA
HsaRAD51C
SceS000000981
SpoSPAC8E11.03c
GO:0005737 cytoplasm C
IDA
HsaRAD51C
GO:0005739 mitochondrion C
IDA
HsaRAD51C
GO:0005829 cytosol C
IDA
SpoSPAC8E11.03c
GO:0048471 perinuclear region of cytoplasm C
IDA
HsaRAD51C
GO:0000150 recombinase activity F
IDA
SpoSPAC8E11.03c
ISS
AthAt2g45280
GO:0003677 DNA binding F
ISS
SpoSPAC8E11.03c
GO:0003684 damaged DNA binding F
ISS
AthAt3g22880
At2g45280
GO:0003690 double-stranded DNA binding F
IDA
SceS000000981
SpoSPAC8E11.03c
GO:0003697 single-stranded DNA binding F
IDA
SceS000000981
SpoSPAC8E11.03c
ISS
AthAt2g45280
GO:0005515 protein binding F
IPI
AthAt2g45280
GO:0005524 ATP binding F
ISS
AthAt2g45280
At3g22880
SpoSPAC8E11.03c
GO:0008094 DNA-dependent ATPase activity F
IDA
SpoSPAC8E11.03c
ISS
AthAt3g22880
GO:0016887 ATPase activity F
RCA
SceS000000981
GO:0042623 ATPase activity, coupled F
RCA
SceS000000981
GO:0042802 identical protein binding F
IPI
SpoSPAC8E11.03c
GO:0000709 meiotic joint molecule formation P
IMP
SceS000000981
ISS
SpoSPAC8E11.03c
GO:0000722 telomere maintenance via recombination P
RCA
SceS000000981
GO:0000724 double-strand break repair via homologous
recombination		 P
IMP
AthAt2g45280
GO:0006200 ATP catabolic process P
IDA
SpoSPAC8E11.03c
GO:0006259 DNA metabolic process P
IDA
AthAt3g22880
GO:0006281 DNA repair P
IDA
HsaRAD51C
ISS
AthAt3g22880
At2g45280
GO:0006310 DNA recombination P
IDA
HsaRAD51C
GO:0006311 meiotic gene conversion P
IMP
SpoSPAC8E11.03c
GO:0007126 meiosis P
IMP
AthAt2g45280
SceS000000981
TAS
AthAt3g22880
GO:0007131 reciprocal meiotic recombination P
IMP
AthAt2g45280
SceS000000981
SpoSPAC8E11.03c
ISS
AthAt3g22880
GO:0007140 male meiosis P
IMP
AthAt2g45280
GO:0007143 female meiosis P
IMP
AthAt2g45280
GO:0016444 somatic cell DNA recombination P
IMP
AthAt2g45280
GO:0030435 sporulation resulting in formation of a cellular
spore		 P
RCA
SceS000000981
GO:0051026 chiasma assembly P
IGI
AthAt3g22880
IMP
AthAt3g22880
GO:0051260 protein homooligomerization P
IPI
SpoSPAC8E11.03c
GO:0051321 meiotic cell cycle P
RCA
SceS000000981

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
5135

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) DMC1 GI:23238219
Pan troglodytes (Ptr) DMC1 GI:114686387
Canis familiaris (Cfa) DMC1 GI:73969089
Mus musculus (Mmu) Dmc1
(MGI:105393)		 GI:6753650 Q14AN8
Rattus norvegicus (Rno) Dmc1 GI:109480994
Gallus gallus (Gga) DMC1 GI:118082782
Schizosaccharomyces pombe (Spo) dmc1
(SPAC8E11.03c)		 GI:19115078 O42634
Saccharomyces cerevisiae (Sce) DMC1
(S000000981)		 GI:6321027 P25453
Kluyveromyces lactis (Kla) KLLA0F11957g GI:50311197
Eremothecium gossypii (Ego) AGOS_AGR101C GI:45201197
Arabidopsis thaliana (Ath) DMC1 GI:30686826
Oryza sativa (Osa) Os12g0143800 GI:115487302
Oryza sativa (Osa) Os11g0146800 GI:115484153
Plasmodium falciparum (Pfa) MAL8P1.76 GI:124512446


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000794 condensed nuclear chromosome C
IDA
MmuMGI:105393
SceS000000981
ISS
PfaMAL8P1.76
SpoSPAC8E11.03c
GO:0005634 nucleus C
IDA
HsaDMC1
SceS000000981
SpoSPAC8E11.03c
GO:0005737 cytoplasm C
IDA
HsaDMC1
GO:0005829 cytosol C
IDA
SpoSPAC8E11.03c
GO:0043231 intracellular membrane-bounded
organelle		 C
IDA
HsaDMC1
GO:0000150 recombinase activity F
IDA
SpoSPAC8E11.03c
GO:0003677 DNA binding F
ISS
SpoSPAC8E11.03c
GO:0003690 double-stranded DNA binding F
IDA
SceS000000981
SpoSPAC8E11.03c
GO:0003697 single-stranded DNA binding F
IDA
SceS000000981
SpoSPAC8E11.03c
GO:0005524 ATP binding F
ISS
SpoSPAC8E11.03c
GO:0008094 DNA-dependent ATPase activity F
IDA
SpoSPAC8E11.03c
GO:0016887 ATPase activity F
RCA
SceS000000981
GO:0042623 ATPase activity, coupled F
RCA
SceS000000981
GO:0042802 identical protein binding F
IPI
SpoSPAC8E11.03c
GO:0000239 pachytene P
IMP
MmuMGI:105393
GO:0000709 meiotic joint molecule formation P
IMP
SceS000000981
ISS
SpoSPAC8E11.03c
GO:0000722 telomere maintenance via recombination P
RCA
SceS000000981
GO:0001541 ovarian follicle development P
IMP
MmuMGI:105393
GO:0001556 oocyte maturation P
IMP
MmuMGI:105393
GO:0006200 ATP catabolic process P
IDA
SpoSPAC8E11.03c
GO:0006311 meiotic gene conversion P
IMP
SpoSPAC8E11.03c
GO:0007126 meiosis P
IMP
SceS000000981
GO:0007131 reciprocal meiotic recombination P
IMP
SceS000000981
SpoSPAC8E11.03c
GO:0007141 male meiosis I P
IMP
MmuMGI:105393
GO:0007276 gamete generation P
IMP
MmuMGI:105393
GO:0007283 spermatogenesis P
IMP
MmuMGI:105393
GO:0007286 spermatid development P
IMP
MmuMGI:105393
GO:0007292 female gamete generation P
TAS
HsaDMC1
GO:0030435 sporulation resulting in formation of a cellular
spore		 P
RCA
SceS000000981
GO:0051260 protein homooligomerization P
IPI
SpoSPAC8E11.03c
GO:0051321 meiotic cell cycle P
RCA
SceS000000981

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2484

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago4412 AGR101C
Arabidopsis thaliana (Ath) ath14601 At3g22880.1
Candida glabrata (Cgl) cgl4602 CAGL0L12100g
Cryptococcus neoformans (Cne) cne1752 164.m02138
Debaryomyces hansenii (Dha) dha4015 DEHA0E17479g
Danio rerio (Dre) dre28729 ENSDARP00000050608
Takifugu rubripes (Fru) fru18952 SINFRUP00000160087
Takifugu rubripes (Fru) fru18953 SINFRUP00000166573
Gallus gallus (Gga) gga904 ENSGALP00000019952
(DMC1)
Gallus gallus (Gga) gga905 ENSGALP00000019953
Homo sapiens (Hsa) hsa21665 ENSP00000216024
(DMC1)		 Q14565
Kluyveromyces lactis (Kla) kla4622 KLLA0F11957g
Mus musculus (Mmu) mmu9302 ENSMUSP00000023065
(MGI:105393)		 Q61880
Mus musculus (Mmu) mmu9303 ENSMUSP00000079785
(MGI:105393)		 Q8C610
Oryza sativa (Osa) osa1698 1891.m00114
Oryza sativa (Osa) osa59903 6552.m00105
Oryza sativa (Osa) osa68613 6914.m00120
Plasmodium falciparum (Pfa) pfa2070 MAL8P1.76
Rattus norvegicus (Rno) rno27397 ENSRNOP00000018526
(RGD:1307611)
Rattus norvegicus (Rno) rno27398 ENSRNOP00000029467
(RGD:1307611)
Saccharomyces cerevisiae (Sce) sce1930 YER179W
(S000000981)
Schizosaccharomyces pombe (Spo) spo411 SPAC8E11.03c O42634


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000794 condensed nuclear chromosome C
IDA
MmuMGI:105393
SceS000000981
ISS
PfaMAL8P1.76
SpoSPAC8E11.03c
GO:0005634 nucleus C
IDA
SceS000000981
SpoSPAC8E11.03c
GO:0005829 cytosol C
IDA
SpoSPAC8E11.03c
GO:0000150 recombinase activity F
IDA
SpoSPAC8E11.03c
GO:0003677 DNA binding F
ISS
SpoSPAC8E11.03c
GO:0003684 damaged DNA binding F
ISS
AthAt3g22880
GO:0003690 double-stranded DNA binding F
IDA
SceS000000981
SpoSPAC8E11.03c
GO:0003697 single-stranded DNA binding F
IDA
SceS000000981
SpoSPAC8E11.03c
GO:0005524 ATP binding F
ISS
AthAt3g22880
SpoSPAC8E11.03c
GO:0008094 DNA-dependent ATPase activity F
IDA
SpoSPAC8E11.03c
ISS
AthAt3g22880
GO:0016887 ATPase activity F
RCA
SceS000000981
GO:0042623 ATPase activity, coupled F
RCA
SceS000000981
GO:0042802 identical protein binding F
IPI
SpoSPAC8E11.03c
GO:0000239 pachytene P
IMP
MmuMGI:105393
GO:0000709 meiotic joint molecule formation P
IMP
SceS000000981
ISS
SpoSPAC8E11.03c
GO:0000722 telomere maintenance via recombination P
RCA
SceS000000981
GO:0001541 ovarian follicle development P
IMP
MmuMGI:105393
GO:0001556 oocyte maturation P
IMP
MmuMGI:105393
GO:0006200 ATP catabolic process P
IDA
SpoSPAC8E11.03c
GO:0006259 DNA metabolic process P
IDA
AthAt3g22880
GO:0006281 DNA repair P
ISS
AthAt3g22880
GO:0006311 meiotic gene conversion P
IMP
SpoSPAC8E11.03c
GO:0007126 meiosis P
IMP
SceS000000981
TAS
AthAt3g22880
GO:0007131 reciprocal meiotic recombination P
IMP
SceS000000981
SpoSPAC8E11.03c
ISS
AthAt3g22880
GO:0007141 male meiosis I P
IMP
MmuMGI:105393
GO:0007276 gamete generation P
IMP
MmuMGI:105393
GO:0007283 spermatogenesis P
IMP
MmuMGI:105393
GO:0007286 spermatid development P
IMP
MmuMGI:105393
GO:0030435 sporulation resulting in formation of a cellular
spore		 P
RCA
SceS000000981
GO:0051026 chiasma assembly P
IGI
AthAt3g22880
IMP
AthAt3g22880
GO:0051260 protein homooligomerization P
IPI
SpoSPAC8E11.03c
GO:0051321 meiotic cell cycle P
RCA
SceS000000981

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC8E11.03c
(O42634)		 YER179W
(S000000981)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000794 condensed nuclear chromosome C
IDA
SceS000000981
ISS
SpoSPAC8E11.03c
GO:0005634 nucleus C
IDA
SceS000000981
SpoSPAC8E11.03c
GO:0005829 cytosol C
IDA
SpoSPAC8E11.03c
GO:0000150 recombinase activity F
IDA
SpoSPAC8E11.03c
GO:0003677 DNA binding F
ISS
SpoSPAC8E11.03c
GO:0003690 double-stranded DNA binding F
IDA
SceS000000981
SpoSPAC8E11.03c
GO:0003697 single-stranded DNA binding F
IDA
SceS000000981
SpoSPAC8E11.03c
GO:0005524 ATP binding F
ISS
SpoSPAC8E11.03c
GO:0008094 DNA-dependent ATPase activity F
IDA
SpoSPAC8E11.03c
GO:0016887 ATPase activity F
RCA
SceS000000981
GO:0042623 ATPase activity, coupled F
RCA
SceS000000981
GO:0042802 identical protein binding F
IPI
SpoSPAC8E11.03c
GO:0000709 meiotic joint molecule formation P
IMP
SceS000000981
ISS
SpoSPAC8E11.03c
GO:0000722 telomere maintenance via recombination P
RCA
SceS000000981
GO:0006200 ATP catabolic process P
IDA
SpoSPAC8E11.03c
GO:0006311 meiotic gene conversion P
IMP
SpoSPAC8E11.03c
GO:0007126 meiosis P
IMP
SceS000000981
GO:0007131 reciprocal meiotic recombination P
IMP
SceS000000981
SpoSPAC8E11.03c
GO:0030435 sporulation resulting in formation of a cellular
spore		 P
RCA
SceS000000981
GO:0051260 protein homooligomerization P
IPI
SpoSPAC8E11.03c
GO:0051321 meiotic cell cycle P
RCA
SceS000000981

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