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Search term: YFL003C


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name MSH4
SGD link S000001891
Alternative ID YFL003C
Description Protein involved in meiotic recombination, required for normal levels of crossing over, colocalizes with Zip2p to discrete foci on meiotic chromosomes, has homology to bacterial MutS protein
Synonyms YFL003C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0220 AC-HY--

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING Mismatch repair ATPase MSH4 (MutS family)

Species KOG link NCBI link UniProt link
Homo sapiens (Hsa) Hs20535615 GI:20535615
Arabidopsis thaliana (Ath) At4g17380 GI:15236048
Caenorhabditis elegans (Cel) CE04858
(WBGene00003420)
GI:17535283 Q22103
Caenorhabditis elegans (Cel) CE24714
(WBGene00001872)
GI:17534743 Q23405
Homo sapiens (Hsa) Hs4505251 GI:4505251
Saccharomyces cerevisiae (Sce) YFL003c
(S000001891)
GI:14318519 P40965
Homo sapiens (Hsa) Hs20535615 GI:20535615
Arabidopsis thaliana (Ath) At4g17380 GI:15236048
Caenorhabditis elegans (Cel) CE04858
(WBGene00003420)
GI:17535283 Q22103
Caenorhabditis elegans (Cel) CE24714
(WBGene00001872)
GI:17534743 Q23405
Homo sapiens (Hsa) Hs4505251 GI:4505251
Saccharomyces cerevisiae (Sce) YFL003c
(S000001891)
GI:14318519 P40965
Homo sapiens (Hsa) Hs20535615 GI:20535615
Arabidopsis thaliana (Ath) At4g17380 GI:15236048
Caenorhabditis elegans (Cel) CE04858
(WBGene00003420)
GI:17535283 Q22103
Caenorhabditis elegans (Cel) CE24714
(WBGene00001872)
GI:17534743 Q23405
Homo sapiens (Hsa) Hs4505251 GI:4505251
Saccharomyces cerevisiae (Sce) YFL003c
(S000001891)
GI:14318519 P40965


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000228 nuclear chromosome C
IDA
SceS000001891
GO:0000794 condensed nuclear chromosome C
IDA
AthAt4g17380
GO:0003677 DNA binding F
IPI
SceS000001891
GO:0003684 damaged DNA binding F
ISS
AthAt4g17380
GO:0005524 ATP binding F
ISS
AthAt4g17380
CelWBGene00001872
GO:0043566 structure-specific DNA binding F
RCA
SceS000001891
GO:0000003 reproduction P
IMP
CelWBGene00003420
WBGene00001872
GO:0006298 mismatch repair P
ISS
AthAt4g17380
GO:0007128 meiotic prophase I P
IMP
AthAt4g17380
GO:0007129 synapsis P
IMP
AthAt4g17380
GO:0007131 reciprocal meiotic recombination P
IMP
CelWBGene00001872
SceS000001891
GO:0009792 embryo development ending in birth or egg
hatching
P
IMP
CelWBGene00003420
WBGene00001872
GO:0045143 homologous chromosome segregation P
IMP
CelWBGene00001872
GO:0051026 chiasma assembly P
IMP
CelWBGene00001872

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
1830

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) MSH4 GI:36949366
Pan troglodytes (Ptr) MSH4 GI:114557223
Canis familiaris (Cfa) MSH4 GI:73960157
Mus musculus (Mmu) Msh4
(MGI:1860077)
GI:13994197 A6H6D5
Rattus norvegicus (Rno) Msh4 GI:109465705
Gallus gallus (Gga) MSH4 GI:118094774
Caenorhabditis elegans (Cel) him-14
(CE24714;
WBGene00001872)
GI:17534743 Q23405
Saccharomyces cerevisiae (Sce) MSH4
(S000001891)
GI:14318519 P40965
Kluyveromyces lactis (Kla) KLLA0F11022g GI:50311117
Magnaporthe grisea (Mgr) MGG_08738 GI:145601257
Arabidopsis thaliana (Ath) MSH4 GI:79476962
Oryza sativa (Osa) Os07g0486000 GI:115472123


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000228 nuclear chromosome C
IDA
SceS000001891
GO:0000793 condensed chromosome C
IDA
MmuMGI:1860077
GO:0000794 condensed nuclear chromosome C
IDA
MmuMGI:1860077
GO:0000795 synaptonemal complex C
IDA
MmuMGI:1860077
ISS
MmuMGI:1860077
GO:0005634 nucleus C
IDA
MmuMGI:1860077
GO:0003677 DNA binding F
IPI
SceS000001891
GO:0005524 ATP binding F
ISS
CelWBGene00001872
GO:0043566 structure-specific DNA binding F
RCA
SceS000001891
GO:0000003 reproduction P
IMP
CelWBGene00001872
GO:0001541 ovarian follicle development P
IMP
MmuMGI:1860077
GO:0007126 meiosis P
IDA
MmuMGI:1860077
IMP
MmuMGI:1860077
GO:0007129 synapsis P
IMP
MmuMGI:1860077
GO:0007131 reciprocal meiotic recombination P
IMP
CelWBGene00001872
SceS000001891
TAS
HsaMSH4
GO:0007283 spermatogenesis P
IMP
MmuMGI:1860077
GO:0007292 female gamete generation P
IMP
MmuMGI:1860077
GO:0009792 embryo development ending in birth or egg
hatching
P
IMP
CelWBGene00001872
GO:0045143 homologous chromosome segregation P
IMP
CelWBGene00001872
GO:0051026 chiasma assembly P
IMP
CelWBGene00001872

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_4548

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Anopheles gambiae (Aga) aga9436 ENSANGP00000016548
Arabidopsis thaliana (Ath) ath19596 At4g17380.1
Caenorhabditis elegans (Cel) cel21565 ZK1127.11
(CE24714;
WBGene00001872)
Candida glabrata (Cgl) cgl1325 CAGL0F02167g
Dictyostelium discoideum (Ddi) ddi13326 DDB0229912
Danio rerio (Dre) dre8586 ENSDARP00000041421
Takifugu rubripes (Fru) fru21122 SINFRUP00000139661
Gallus gallus (Gga) gga23020 ENSGALP00000018559
(MSH4)
Homo sapiens (Hsa) hsa1371 ENSP00000263187
(MSH4)
O15457
Kluyveromyces lactis (Kla) kla4582 KLLA0F11022g
Mus musculus (Mmu) mmu17732 ENSMUSP00000005630
(MGI:1860077)
Q99MT2
Oryza sativa (Osa) osa19905 3383.m00092
Oryza sativa (Osa) osa39213 5090.m00055
Oryza sativa (Osa) osa70772 7150.m00121
Rattus norvegicus (Rno) rno17195 ENSRNOP00000014106
(RGD:1309190)
Saccharomyces cerevisiae (Sce) sce1951 YFL003C
(S000001891)


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000228 nuclear chromosome C
IDA
SceS000001891
GO:0000793 condensed chromosome C
IDA
MmuMGI:1860077
GO:0000794 condensed nuclear chromosome C
IDA
AthAt4g17380
MmuMGI:1860077
GO:0000795 synaptonemal complex C
IDA
MmuMGI:1860077
ISS
MmuMGI:1860077
GO:0005634 nucleus C
IDA
MmuMGI:1860077
GO:0003677 DNA binding F
IPI
SceS000001891
GO:0003684 damaged DNA binding F
ISS
AthAt4g17380
GO:0005524 ATP binding F
ISS
AthAt4g17380
CelWBGene00001872
GO:0043566 structure-specific DNA binding F
RCA
SceS000001891
GO:0000003 reproduction P
IMP
CelWBGene00001872
GO:0001541 ovarian follicle development P
IMP
MmuMGI:1860077
GO:0006298 mismatch repair P
ISS
AthAt4g17380
GO:0007126 meiosis P
IDA
MmuMGI:1860077
IMP
MmuMGI:1860077
GO:0007128 meiotic prophase I P
IMP
AthAt4g17380
GO:0007129 synapsis P
IMP
AthAt4g17380
MmuMGI:1860077
GO:0007131 reciprocal meiotic recombination P
IMP
CelWBGene00001872
SceS000001891
GO:0007283 spermatogenesis P
IMP
MmuMGI:1860077
GO:0007292 female gamete generation P
IMP
MmuMGI:1860077
GO:0009792 embryo development ending in birth or egg
hatching
P
IMP
CelWBGene00001872
GO:0045143 homologous chromosome segregation P
IMP
CelWBGene00001872
GO:0051026 chiasma assembly P
IMP
CelWBGene00001872

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GO info in one table:

s.khadayate@ucl.ac.uk