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Search term: YFL005W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name SEC4
SGD link S000001889
Alternative ID YFL005W
Description Secretory vesicle-associated Rab GTPase essential for exocytosis; associates with the exocyst component Sec15p and may regulate polarized delivery of transport vesicles to the exocyst at the plasma membrane
Synonyms YFL005W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0078 ACDHYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALINGCELLULAR PROCESSES AND SIGNALING GTP-binding protein SEC4, small G protein superfamily, and related Ras family GTP-binding proteins

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At3g09900 GI:15232784
Arabidopsis thaliana (Ath) At3g46060 GI:15231322
Arabidopsis thaliana (Ath) At3g53610 GI:15231847
Arabidopsis thaliana (Ath) At5g03520 GI:15242773
Arabidopsis thaliana (Ath) At5g59840 GI:15238542
Caenorhabditis elegans (Cel) CE04693 GI:17568619
Caenorhabditis elegans (Cel) CE14114
(WBGene00004273)		 GI:17509233 Q94148
Caenorhabditis elegans (Cel) CE19030
(WBGene00004281)		 GI:17542952 Q9XWR6
Caenorhabditis elegans (Cel) CE19650
(WBGene00007067)		 GI:17538174 Q9XXA4
Caenorhabditis elegans (Cel) CE20623 GI:17506347
Caenorhabditis elegans (Cel) CE27102
(WBGene00016344)		 GI:17550768 Q22908
Caenorhabditis elegans (Cel) CE27318
(WBGene00022177)		 GI:17556434 Q9BL44
Drosophila melanogaster (Dme) 7292769 GI:7292769
Drosophila melanogaster (Dme) 7293732
(FBgn0015796)		 GI:17737663
Drosophila melanogaster (Dme) 7295615
(FBgn0015789)		 GI:17737369
Drosophila melanogaster (Dme) 7301214_2 GI:7301214
Homo sapiens (Hsa) Hs16933567
(RAB8A)		 GI:16933567 P61006
Homo sapiens (Hsa) Hs18373308 GI:18373308
Homo sapiens (Hsa) Hs18373331 GI:18373331
Homo sapiens (Hsa) Hs18572474 GI:18572474
Homo sapiens (Hsa) Hs18580804 GI:18580804
Homo sapiens (Hsa) Hs18596424 GI:18596424
Homo sapiens (Hsa) Hs20556496_2 GI:20556496
Homo sapiens (Hsa) Hs20557736 GI:20557736
Homo sapiens (Hsa) Hs22041162 GI:22041162
Homo sapiens (Hsa) Hs22048268 GI:22048268
Homo sapiens (Hsa) Hs4506363
(RAB13)		 GI:4506363 P51153
Homo sapiens (Hsa) Hs4758994 GI:4758994
Homo sapiens (Hsa) Hs5803163
(RAB40B)		 GI:5803163 Q12829
Homo sapiens (Hsa) Hs7705849 GI:7705849
Homo sapiens (Hsa) Hs7706563
(RAB8B)		 GI:7706563 Q92930
Saccharomyces cerevisiae (Sce) YFL005w
(S000001889)		 GI:14318517 P07560
Schizosaccharomyces pombe (Spo) SPAC9E9.07c GI:19115492 P17609
Arabidopsis thaliana (Ath) At3g09900 GI:15232784
Arabidopsis thaliana (Ath) At3g46060 GI:15231322
Arabidopsis thaliana (Ath) At3g53610 GI:15231847
Arabidopsis thaliana (Ath) At5g03520 GI:15242773
Arabidopsis thaliana (Ath) At5g59840 GI:15238542
Caenorhabditis elegans (Cel) CE04693 GI:17568619
Caenorhabditis elegans (Cel) CE14114
(WBGene00004273)		 GI:17509233 Q94148
Caenorhabditis elegans (Cel) CE19030
(WBGene00004281)		 GI:17542952 Q9XWR6
Caenorhabditis elegans (Cel) CE19650
(WBGene00007067)		 GI:17538174 Q9XXA4
Caenorhabditis elegans (Cel) CE20623 GI:17506347
Caenorhabditis elegans (Cel) CE27102
(WBGene00016344)		 GI:17550768 Q22908
Caenorhabditis elegans (Cel) CE27318
(WBGene00022177)		 GI:17556434 Q9BL44
Drosophila melanogaster (Dme) 7292769 GI:7292769
Drosophila melanogaster (Dme) 7293732
(FBgn0015796)		 GI:17737663
Drosophila melanogaster (Dme) 7295615
(FBgn0015789)		 GI:17737369
Drosophila melanogaster (Dme) 7301214_2 GI:7301214
Homo sapiens (Hsa) Hs16933567
(RAB8A)		 GI:16933567 P61006
Homo sapiens (Hsa) Hs18373308 GI:18373308
Homo sapiens (Hsa) Hs18373331 GI:18373331
Homo sapiens (Hsa) Hs18572474 GI:18572474
Homo sapiens (Hsa) Hs18580804 GI:18580804
Homo sapiens (Hsa) Hs18596424 GI:18596424
Homo sapiens (Hsa) Hs20556496_2 GI:20556496
Homo sapiens (Hsa) Hs20557736 GI:20557736
Homo sapiens (Hsa) Hs22041162 GI:22041162
Homo sapiens (Hsa) Hs22048268 GI:22048268
Homo sapiens (Hsa) Hs4506363
(RAB13)		 GI:4506363 P51153
Homo sapiens (Hsa) Hs4758994 GI:4758994
Homo sapiens (Hsa) Hs5803163
(RAB40B)		 GI:5803163 Q12829
Homo sapiens (Hsa) Hs7705849 GI:7705849
Homo sapiens (Hsa) Hs7706563
(RAB8B)		 GI:7706563 Q92930
Saccharomyces cerevisiae (Sce) YFL005w
(S000001889)		 GI:14318517 P07560
Schizosaccharomyces pombe (Spo) SPAC9E9.07c GI:19115492 P17609
Arabidopsis thaliana (Ath) At3g09900 GI:15232784
Arabidopsis thaliana (Ath) At3g46060 GI:15231322
Arabidopsis thaliana (Ath) At3g53610 GI:15231847
Arabidopsis thaliana (Ath) At5g03520 GI:15242773
Arabidopsis thaliana (Ath) At5g59840 GI:15238542
Caenorhabditis elegans (Cel) CE04693 GI:17568619
Caenorhabditis elegans (Cel) CE14114
(WBGene00004273)		 GI:17509233 Q94148
Caenorhabditis elegans (Cel) CE19030
(WBGene00004281)		 GI:17542952 Q9XWR6
Caenorhabditis elegans (Cel) CE19650
(WBGene00007067)		 GI:17538174 Q9XXA4
Caenorhabditis elegans (Cel) CE20623 GI:17506347
Caenorhabditis elegans (Cel) CE27102
(WBGene00016344)		 GI:17550768 Q22908
Caenorhabditis elegans (Cel) CE27318
(WBGene00022177)		 GI:17556434 Q9BL44
Drosophila melanogaster (Dme) 7292769 GI:7292769
Drosophila melanogaster (Dme) 7293732
(FBgn0015796)		 GI:17737663
Drosophila melanogaster (Dme) 7295615
(FBgn0015789)		 GI:17737369
Drosophila melanogaster (Dme) 7301214_2 GI:7301214
Homo sapiens (Hsa) Hs16933567
(RAB8A)		 GI:16933567 P61006
Homo sapiens (Hsa) Hs18373308 GI:18373308
Homo sapiens (Hsa) Hs18373331 GI:18373331
Homo sapiens (Hsa) Hs18572474 GI:18572474
Homo sapiens (Hsa) Hs18580804 GI:18580804
Homo sapiens (Hsa) Hs18596424 GI:18596424
Homo sapiens (Hsa) Hs20556496_2 GI:20556496
Homo sapiens (Hsa) Hs20557736 GI:20557736
Homo sapiens (Hsa) Hs22041162 GI:22041162
Homo sapiens (Hsa) Hs22048268 GI:22048268
Homo sapiens (Hsa) Hs4506363
(RAB13)		 GI:4506363 P51153
Homo sapiens (Hsa) Hs4758994 GI:4758994
Homo sapiens (Hsa) Hs5803163
(RAB40B)		 GI:5803163 Q12829
Homo sapiens (Hsa) Hs7705849 GI:7705849
Homo sapiens (Hsa) Hs7706563
(RAB8B)		 GI:7706563 Q92930
Saccharomyces cerevisiae (Sce) YFL005w
(S000001889)		 GI:14318517 P07560
Schizosaccharomyces pombe (Spo) SPAC9E9.07c GI:19115492 P17609


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000131 incipient cellular bud site C
IDA
SceS000001889
GO:0001950 plasma membrane enriched fraction C
IDA
SceS000001889
GO:0005575 cellular_component C
ND
HsaRAB8B
GO:0005634 nucleus C
IDA
SpoSPAC9E9.07c
GO:0005739 mitochondrion C
IDA
SceS000001889
GO:0005741 mitochondrial outer membrane C
IDA
SceS000001889
GO:0005769 early endosome C
IDA
CelWBGene00004273
GO:0005773 vacuole C
IDA
AthAt3g46060
GO:0005794 Golgi apparatus C
IDA
CelWBGene00004273
GO:0005829 cytosol C
IDA
SpoSPAC9E9.07c
GO:0005886 plasma membrane C
IDA
AthAt5g59840
At3g09900
At3g46060
At3g53610
GO:0030133 transport vesicle C
TAS
SceS000001889
GO:0030478 actin cap C
TAS
SceS000001889
GO:0031513 nonmotile primary cilium C
IDA
HsaRAB8A
GO:0031982 vesicle C
IDA
SceS000001889
GO:0043025 neuronal cell body C
IDA
CelWBGene00004273
GO:0003924 GTPase activity F
IDA
SceS000001889
ISS
DmeFBgn0015789
FBgn0015796
NAS
DmeFBgn0015796
HsaRAB8B
TAS
HsaRAB13
SpoSPAC9E9.07c
GO:0005515 protein binding F
IPI
HsaRAB8A
RAB8B
GO:0005525 GTP binding F
IDA
SceS000001889
SpoSPAC9E9.07c
ISS
AthAt3g46060
At3g53610
At5g03520
At3g09900
At5g59840
GO:0030234 enzyme regulator activity F
RCA
SceS000001889
GO:0000003 reproduction P
IMP
CelWBGene00004273
GO:0000910 cytokinesis P
TAS
SceS000001889
GO:0001881 receptor recycling P
IMP
CelWBGene00004273
GO:0002009 morphogenesis of an epithelium P
IMP
CelWBGene00004273
GO:0002119 nematode larval development P
IMP
CelWBGene00004273
GO:0006184 GTP catabolic process P
TAS
SpoSPAC9E9.07c
GO:0006886 intracellular protein transport P
IC
SpoSPAC9E9.07c
GO:0006887 exocytosis P
IDA
SceS000001889
IMP
SpoSPAC9E9.07c
GO:0006893 Golgi to plasma membrane transport P
IGI
SpoSPAC9E9.07c
IMP
SceS000001889
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00004273
GO:0006904 vesicle docking involved in exocytosis P
IDA
HsaRAB8A
GO:0006906 vesicle fusion P
IGI
SpoSPAC9E9.07c
IMP
SceS000001889
GO:0006914 autophagy P
IGI
SceS000001889
IMP
SceS000001889
GO:0007107 membrane addition at site of cytokinesis P
IEP
SceS000001889
IGI
SceS000001889
IMP
SceS000001889
GO:0007121 bipolar cellular bud site selection P
TAS
SceS000001889
GO:0007155 cell adhesion P
TAS
HsaRAB13
GO:0007264 small GTPase mediated signal transduction P
TAS
SceS000001889
GO:0008340 determination of adult lifespan P
IMP
CelWBGene00004273
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00004273
GO:0009873 ethylene mediated signaling pathway P
IEP
AthAt3g46060
GO:0015031 protein transport P
NAS
HsaRAB8B
GO:0016050 vesicle organization P
RCA
SceS000001889
GO:0016192 vesicle-mediated transport P
TAS
HsaRAB13
GO:0031321 ascospore-type prospore formation P
IMP
SceS000001889
GO:0032456 endocytic recycling P
IMP
CelWBGene00004273
GO:0032940 secretion by cell P
IMP
CelWBGene00004273
GO:0040002 collagen and cuticulin-based cuticle
development		 P
IMP
CelWBGene00004273
GO:0040007 growth P
IMP
CelWBGene00004273
GO:0040018 positive regulation of multicellular organism
growth		 P
IMP
CelWBGene00004273
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00004273
GO:0042384 cilium assembly P
IDA
HsaRAB8A
GO:0048210 Golgi vesicle fusion to target
membrane		 P
IDA
HsaRAB8A
GO:0048284 organelle fusion P
RCA
SceS000001889

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
100934

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) RAB8A GI:16933567 P61006
Canis familiaris (Cfa) RAB8A GI:73985097
Mus musculus (Mmu) Rab8a
(MGI:96960)		 GI:38372905 P55258
Gallus gallus (Gga) RCJMB04_2k8 GI:71895669
Drosophila melanogaster (Dme) Rab8
(FBgn0015796)		 GI:17737663
Caenorhabditis elegans (Cel) rab-8
(CE30373;
WBGene00004272)		 GI:25150215
Schizosaccharomyces pombe (Spo) ypt2
(SPAC9E9.07c)		 GI:19115492 P17609
Saccharomyces cerevisiae (Sce) SEC4
(S000001889)		 GI:14318517 P07560
Kluyveromyces lactis (Kla) KLLA0E12111g GI:50308977
Eremothecium gossypii (Ego) AGOS_AGL021W GI:45201075
Magnaporthe grisea (Mgr) MGG_06135 GI:39975877
Neurospora crassa (Ncr) NCU06404.1 GI:32411557
Arabidopsis thaliana (Ath) ATRAB8 GI:145332825
Arabidopsis thaliana (Ath) ATRAB8A GI:145332765
Arabidopsis thaliana (Ath) AT5G59840 GI:15238542
Oryza sativa (Osa) Os05g0461300 GI:115464323
Oryza sativa (Osa) Os03g0819900 GI:115456231
Oryza sativa (Osa) Os07g0239400 GI:115471321