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Search term: YFL009W


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name CDC4
SGD link S000001885
Alternative ID YFL009W
Description F-box protein required for G1/S and G2/M transition, associates with Skp1p and Cdc53p to form a complex, SCFCdc4, which acts as ubiquitin-protein ligase directing ubiquitination of the phosphorylated CDK inhibitor Sic1p
Synonyms YFL009W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0274 ACDHYPE

KOGs classification KOGs description
POORLY CHARACTERIZED Cdc4 and related F-box and WD-40 proteins

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At4g25440_1 GI:15235075
Arabidopsis thaliana (Ath) At5g21040 GI:15242140
Arabidopsis thaliana (Ath) At5g40880 GI:15237513
Arabidopsis thaliana (Ath) At5g49200 GI:15239819
Arabidopsis thaliana (Ath) At5g51980 GI:15242242
Caenorhabditis elegans (Cel) CE02308
(WBGene00011332)
GI:17535893 Q22071
Caenorhabditis elegans (Cel) CE25007 GI:17563260 Q93794
Caenorhabditis elegans (Cel) CE27762 GI:17563262
Drosophila melanogaster (Dme) 7292465 GI:17737533
Homo sapiens (Hsa) Hs11024696 GI:11024696
Homo sapiens (Hsa) Hs13994164_1 GI:13994164
Homo sapiens (Hsa) Hs14150011_2 GI:14150011
Homo sapiens (Hsa) Hs15812196
(FBXO24)
GI:15812196 O75426
Homo sapiens (Hsa) Hs16117779 GI:16117779 Q969H0
Homo sapiens (Hsa) Hs16117781
(FBXW7)
GI:16117781 Q969H0
Homo sapiens (Hsa) Hs22047819 GI:22047819
Homo sapiens (Hsa) Hs22047943 GI:22047943
Homo sapiens (Hsa) Hs22058783 GI:22058783
Homo sapiens (Hsa) Hs5453581 GI:5453581
Homo sapiens (Hsa) Hs6912360 GI:6912360
Saccharomyces cerevisiae (Sce) YER066w
(S000000868)
GI:6320909 P40042
Saccharomyces cerevisiae (Sce) YFL009w
(S000001885)
GI:14318513 P07834
Saccharomyces cerevisiae (Sce) YIL046w
(S000001308)
GI:6322143 P39014
Saccharomyces cerevisiae (Sce) YML088w
(S000004553)
GI:6323551 Q04511
Schizosaccharomyces pombe (Spo) SPAC4D7.03 GI:19115868 O14170
Schizosaccharomyces pombe (Spo) SPAC57A10.05c GI:19114222 P87053
Schizosaccharomyces pombe (Spo) SPBC1703.06 GI:19112993 Q9P7W4
Schizosaccharomyces pombe (Spo) SPBC2G2.18 GI:19113239
Encephalitozoon cuniculi (Ecu) ECU01g1300 GI:19075143
Arabidopsis thaliana (Ath) At4g25440_1 GI:15235075
Arabidopsis thaliana (Ath) At5g21040 GI:15242140
Arabidopsis thaliana (Ath) At5g40880 GI:15237513
Arabidopsis thaliana (Ath) At5g49200 GI:15239819
Arabidopsis thaliana (Ath) At5g51980 GI:15242242
Caenorhabditis elegans (Cel) CE02308
(WBGene00011332)
GI:17535893 Q22071
Caenorhabditis elegans (Cel) CE25007 GI:17563260 Q93794
Caenorhabditis elegans (Cel) CE27762 GI:17563262
Drosophila melanogaster (Dme) 7292465 GI:17737533
Homo sapiens (Hsa) Hs11024696 GI:11024696
Homo sapiens (Hsa) Hs13994164_1 GI:13994164
Homo sapiens (Hsa) Hs14150011_2 GI:14150011
Homo sapiens (Hsa) Hs15812196
(FBXO24)
GI:15812196 O75426
Homo sapiens (Hsa) Hs16117779 GI:16117779 Q969H0
Homo sapiens (Hsa) Hs16117781
(FBXW7)
GI:16117781 Q969H0
Homo sapiens (Hsa) Hs22047819 GI:22047819
Homo sapiens (Hsa) Hs22047943 GI:22047943
Homo sapiens (Hsa) Hs22058783 GI:22058783
Homo sapiens (Hsa) Hs5453581 GI:5453581
Homo sapiens (Hsa) Hs6912360 GI:6912360
Saccharomyces cerevisiae (Sce) YER066w
(S000000868)
GI:6320909 P40042
Saccharomyces cerevisiae (Sce) YFL009w
(S000001885)
GI:14318513 P07834
Saccharomyces cerevisiae (Sce) YIL046w
(S000001308)
GI:6322143 P39014
Saccharomyces cerevisiae (Sce) YML088w
(S000004553)
GI:6323551 Q04511
Schizosaccharomyces pombe (Spo) SPAC4D7.03 GI:19115868 O14170
Schizosaccharomyces pombe (Spo) SPAC57A10.05c GI:19114222 P87053
Schizosaccharomyces pombe (Spo) SPBC1703.06 GI:19112993 Q9P7W4
Schizosaccharomyces pombe (Spo) SPBC2G2.18 GI:19113239
Encephalitozoon cuniculi (Ecu) ECU01g1300 GI:19075143
Arabidopsis thaliana (Ath) At4g25440_1 GI:15235075
Arabidopsis thaliana (Ath) At5g21040 GI:15242140
Arabidopsis thaliana (Ath) At5g40880 GI:15237513
Arabidopsis thaliana (Ath) At5g49200 GI:15239819
Arabidopsis thaliana (Ath) At5g51980 GI:15242242
Caenorhabditis elegans (Cel) CE02308
(WBGene00011332)
GI:17535893 Q22071
Caenorhabditis elegans (Cel) CE25007 GI:17563260 Q93794
Caenorhabditis elegans (Cel) CE27762 GI:17563262
Drosophila melanogaster (Dme) 7292465 GI:17737533
Homo sapiens (Hsa) Hs11024696 GI:11024696
Homo sapiens (Hsa) Hs13994164_1 GI:13994164
Homo sapiens (Hsa) Hs14150011_2 GI:14150011
Homo sapiens (Hsa) Hs15812196
(FBXO24)
GI:15812196 O75426
Homo sapiens (Hsa) Hs16117779 GI:16117779 Q969H0
Homo sapiens (Hsa) Hs16117781
(FBXW7)
GI:16117781 Q969H0
Homo sapiens (Hsa) Hs22047819 GI:22047819
Homo sapiens (Hsa) Hs22047943 GI:22047943
Homo sapiens (Hsa) Hs22058783 GI:22058783
Homo sapiens (Hsa) Hs5453581 GI:5453581
Homo sapiens (Hsa) Hs6912360 GI:6912360
Saccharomyces cerevisiae (Sce) YER066w
(S000000868)
GI:6320909 P40042
Saccharomyces cerevisiae (Sce) YFL009w
(S000001885)
GI:14318513 P07834
Saccharomyces cerevisiae (Sce) YIL046w
(S000001308)
GI:6322143 P39014
Saccharomyces cerevisiae (Sce) YML088w
(S000004553)
GI:6323551 Q04511
Schizosaccharomyces pombe (Spo) SPAC4D7.03 GI:19115868 O14170
Schizosaccharomyces pombe (Spo) SPAC57A10.05c GI:19114222 P87053
Schizosaccharomyces pombe (Spo) SPBC1703.06 GI:19112993 Q9P7W4
Schizosaccharomyces pombe (Spo) SPBC2G2.18 GI:19113239
Encephalitozoon cuniculi (Ecu) ECU01g1300 GI:19075143


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000151 ubiquitin ligase complex C
ISS
SpoSPBC1703.06
NAS
HsaFBXO24
GO:0000152 nuclear ubiquitin ligase complex C
ISS
SpoSPAC57A10.05c
GO:0005575 cellular_component C
ND
AthAt5g40880
At5g51980
At4g25440
SceS000000868
GO:0005634 nucleus C
IDA
SceS000001885
S000001308
S000004553
SpoSPAC57A10.05c
GO:0005635 nuclear envelope C
IDA
SpoSPAC4D7.03
GO:0005737 cytoplasm C
IDA
SceS000004553
SpoSPBC1703.06
GO:0005829 cytosol C
IDA
SpoSPBC1703.06
GO:0016363 nuclear matrix C
IDA
SceS000001885
GO:0019005 SCF ubiquitin ligase complex C
IDA
SceS000001885
SpoSPAC4D7.03
SPAC57A10.05c
IPI
SceS000001885
S000001308
S000004553
ISS
AthAt5g21040
GO:0043224 nuclear SCF ubiquitin ligase complex C
IDA
SceS000001308
S000001885
GO:0003674 molecular_function F
ND
AthAt5g21040
SceS000000868
GO:0003676 nucleic acid binding F
ISS
AthAt5g40880
At5g49200
At5g51980
GO:0004842 ubiquitin-protein ligase activity F
IDA
SceS000001885
IMP
SceS000004553
NAS
HsaFBXO24
RCA
SceS000001308
GO:0005515 protein binding F
IDA
SceS000004553
IPI
SpoSPAC57A10.05c
SPBC1703.06
SPAC4D7.03
TAS
SceS000001308
GO:0016874 ligase activity F
RCA
SceS000001308
GO:0016879 ligase activity, forming carbon-nitrogen
bonds
F
RCA
SceS000001308
GO:0016881 acid-amino acid ligase activity F
RCA
SceS000001308
GO:0019787 small conjugating protein ligase
activity
F
RCA
SceS000001308
GO:0030674 protein binding, bridging F
ISS
SpoSPAC57A10.05c
SPBC1703.06
SPAC4D7.03
GO:0042802 identical protein binding F
IPI
SpoSPAC4D7.03
GO:0000082 G1/S transition of mitotic cell
cycle
P
IMP
SceS000001885
S000001308
GO:0000086 G2/M transition of mitotic cell
cycle
P
IGI
SceS000001885
IMP
SceS000001885
GO:0000087 M phase of mitotic cell cycle P
IMP
SceS000001308
GO:0000114 regulation of transcription involved in G1 phase
of mitotic cell cycle
P
IMP
SceS000001308
GO:0000278 mitotic cell cycle P
IC
SpoSPAC57A10.05c
GO:0006511 ubiquitin-dependent protein catabolic
process
P
IMP
SceS000004553
IPI
SceS000004553
TAS
SpoSPAC4D7.03
GO:0006974 response to DNA damage stimulus P
IMP
SceS000004553
IPI
SceS000004553
GO:0007126 meiosis P
IMP
SceS000001885
GO:0007346 regulation of mitotic cell cycle P
IC
SpoSPAC4D7.03
GO:0008150 biological_process P
ND
AthAt4g25440
At5g49200
At5g51980
SceS000000868
SpoSPBC1703.06
GO:0016036 cellular response to phosphate
starvation
P
IMP
AthAt5g21040
GO:0016567 protein ubiquitination P
IGI
SceS000001308
IPI
SceS000001308
NAS
HsaFBXO24
GO:0030174 regulation of DNA-dependent DNA replication
initiation
P
IMP
SceS000001308
GO:0031146 SCF-dependent proteasomal ubiquitin-dependent
protein catabolic process
P
IDA
SceS000001885
S000001308
GO:0032876 negative regulation of DNA endoreduplication P
IMP
SpoSPAC4D7.03
GO:0042787 protein ubiquitination involved in
ubiquitin-dependent protein catabolic
process
P
IDA
SceS000001885
IPI
SpoSPAC57A10.05c
RCA
SceS000001308
GO:0046685 response to arsenic P
IDA
SceS000001308
GO:0046686 response to cadmium ion P
IDA
SceS000001308
GO:0051325 interphase P
RCA
SceS000001885
GO:0071276 cellular response to cadmium ion P
IEP
SpoSPAC57A10.05c
IGI
SpoSPAC57A10.05c

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
118010

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) CDC4
(S000001885)
GI:14318513 P07834
Kluyveromyces lactis (Kla) KLLA0D07546g GI:50306847
Eremothecium gossypii (Ego) AGOS_AGL024W GI:45201072


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000001885
GO:0016363 nuclear matrix C
IDA
SceS000001885
GO:0019005 SCF ubiquitin ligase complex C
IDA
SceS000001885
IPI
SceS000001885
GO:0043224 nuclear SCF ubiquitin ligase complex C
IDA
SceS000001885
GO:0004842 ubiquitin-protein ligase activity F
IDA
SceS000001885
GO:0000082 G1/S transition of mitotic cell
cycle
P
IMP
SceS000001885
GO:0000086 G2/M transition of mitotic cell
cycle
P
IGI
SceS000001885
IMP
SceS000001885
GO:0007126 meiosis P
IMP
SceS000001885
GO:0031146 SCF-dependent proteasomal ubiquitin-dependent
protein catabolic process
P
IDA
SceS000001885
GO:0042787 protein ubiquitination involved in
ubiquitin-dependent protein catabolic
process
P
IDA
SceS000001885
GO:0051325 interphase P
RCA
SceS000001885

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1087

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Anopheles gambiae (Aga) aga769 ENSANGP00000020955
Ashbya gossypii (Ago) ago1659 ADL082C
Ashbya gossypii (Ago) ago4287 AGL024W
Caenorhabditis elegans (Cel) cel10362 F55B12.3a
Caenorhabditis elegans (Cel) cel10363 F55B12.3b
(CE27762)
Candida glabrata (Cgl) cgl4112 CAGL0L00781g
Candida glabrata (Cgl) cgl4189 CAGL0L02629g
Cryptococcus neoformans (Cne) cne1166 180.m00094
Cryptococcus neoformans (Cne) cne2381 181.m08417
Dictyostelium discoideum (Ddi) ddi9290 DDB0186817
Dictyostelium discoideum (Ddi) ddi223 DDB0190268
Dictyostelium discoideum (Ddi) ddi6717 DDB0206452
Debaryomyces hansenii (Dha) dha3014 DEHA0D15950g
Debaryomyces hansenii (Dha) dha4745 DEHA0F08206g
Drosophila melanogaster (Dme) dme7940 CG15010-PA
(FBgn0041171)
Drosophila melanogaster (Dme) dme7939 CG15010-PB
(FBgn0041171)
Drosophila melanogaster (Dme) dme7938 CG15010-PC
(FBgn0041171)
Danio rerio (Dre) dre558 ENSDARP00000013323
Danio rerio (Dre) dre561 ENSDARP00000036258
Encephalitozoon cuniculi (Ecu) ecu1780 19075143
Takifugu rubripes (Fru) fru1149 SINFRUP00000129810
Takifugu rubripes (Fru) fru22717 SINFRUP00000140149
Takifugu rubripes (Fru) fru1150 SINFRUP00000173070
Gallus gallus (Gga) gga17391 ENSGALP00000016409
(FBXW7)
Gallus gallus (Gga) gga17392 ENSGALP00000016410
Gallus gallus (Gga) gga17393 ENSGALP00000016411
Gallus gallus (Gga) gga3529 ENSGALP00000027965
(LOC419074)
Homo sapiens (Hsa) hsa24740 ENSP00000263981
(FBXW7)
Q969H0-2
Homo sapiens (Hsa) hsa24741 ENSP00000281708
(FBXW7)
Q969H0-1
Homo sapiens (Hsa) hsa24739 ENSP00000296555
(FBXW7)
Q969H0-4
Kluyveromyces lactis (Kla) kla2398 KLLA0D07546g
Kluyveromyces lactis (Kla) kla5304 KLLA0F27511g
Mus musculus (Mmu) mmu16836 ENSMUSP00000029727
(MGI:1354695)
Q8VBV4
Neurospora crassa (Ncr) ncr5773 NCU05939.2
Neurospora crassa (Ncr) ncr6301 NCU06483.2
Neurospora crassa (Ncr) ncr8345 NCU08563.2
Rattus norvegicus (Rno) rno16290 ENSRNOP00000015280
Saccharomyces cerevisiae (Sce) sce1956 YFL009W
(S000001885)
Saccharomyces cerevisiae (Sce) sce3060 YIL046W
(S000001308)
Schizosaccharomyces pombe (Spo) spo3970 SPAC4D7.03 O14170
Schizosaccharomyces pombe (Spo) spo3204 SPAC57A10.05c P87053
Schizosaccharomyces pombe (Spo) spo4695 SPBC1718.01 P87060
Yarrowia lipolytica (Yli) yli318 YALI0A09658g
Yarrowia lipolytica (Yli) yli1145 YALI0B09977g
Yarrowia lipolytica (Yli) yli4492 YALI0E15290g