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Search term: YFL025C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name BST1
SGD link S000001869
Alternative ID YFL025C
Description GPI inositol deacylase of the ER that negatively regulates COPII vesicle formation, prevents production of vesicles with defective subunits, required for proper discrimination between resident ER proteins and Golgi-bound cargo molecules
Synonyms YFL025C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG3724 ACDHYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Negative regulator of COPII vesicle formation

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At3g27325 GI:15229470
Caenorhabditis elegans (Cel) CE06462
(WBGene00011835)		 GI:17564402 Q22561
Drosophila melanogaster (Dme) 7290613 GI:7290613
Homo sapiens (Hsa) Hs13376494 GI:13376494
Saccharomyces cerevisiae (Sce) YFL025c
(S000001869)		 GI:14318494 P43571
Schizosaccharomyces pombe (Spo) SPAC824.02 GI:19114353 Q9UT41


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005783 endoplasmic reticulum C
IDA
AthAt3g27325
SceS000001869
SpoSPAC824.02
GO:0005789 endoplasmic reticulum membrane C
IC
SpoSPAC824.02
GO:0005794 Golgi apparatus C
IDA
SpoSPAC824.02
GO:0005886 plasma membrane C
IDA
AthAt3g27325
GO:0016021 integral to membrane C
ISS
SceS000001869
GO:0050185 phosphatidylinositol deacylase
activity		 F
IGI
SceS000001869
ISS
SpoSPAC824.02
GO:0006505 GPI anchor metabolic process P
IGI
SceS000001869
ISS
SpoSPAC824.02
GO:0006621 protein retention in ER lumen P
IMP
SceS000001869
ISS
SpoSPAC824.02
GO:0006888 ER to Golgi vesicle-mediated transport P
IMP
SceS000001869
ISS
SpoSPAC824.02
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00011835
GO:0016050 vesicle organization P
IGI
SceS000001869
IMP
SceS000001869
ISS
SpoSPAC824.02
GO:0030433 ER-associated protein catabolic
process		 P
IMP
SceS000001869
GO:0046488 phosphatidylinositol metabolic
process		 P
IC
SpoSPAC824.02

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
32809

Species Gene ID NCBI link UniProt link
Schizosaccharomyces pombe (Spo) SPAC824.02 GI:19114353 Q9UT41
Saccharomyces cerevisiae (Sce) BST1
(S000001869)		 GI:14318494 P43571
Kluyveromyces lactis (Kla) KLLA0F25124g GI:50312333
Eremothecium gossypii (Ego) AGOS_AFR521W GI:45199039
Magnaporthe grisea (Mgr) MGG_01844 GI:145613151
Neurospora crassa (Ncr) NCU08021.1 GI:32416498


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005783 endoplasmic reticulum C
IDA
SceS000001869
SpoSPAC824.02
GO:0005789 endoplasmic reticulum membrane C
IC
SpoSPAC824.02
GO:0005794 Golgi apparatus C
IDA
SpoSPAC824.02
GO:0016021 integral to membrane C
ISS
SceS000001869
GO:0050185 phosphatidylinositol deacylase
activity		 F
IGI
SceS000001869
ISS
SpoSPAC824.02
GO:0006505 GPI anchor metabolic process P
IGI
SceS000001869
ISS
SpoSPAC824.02
GO:0006621 protein retention in ER lumen P
IMP
SceS000001869
ISS
SpoSPAC824.02
GO:0006888 ER to Golgi vesicle-mediated transport P
IMP
SceS000001869
ISS
SpoSPAC824.02
GO:0016050 vesicle organization P
IGI
SceS000001869
IMP
SceS000001869
ISS
SpoSPAC824.02
GO:0030433 ER-associated protein catabolic
process		 P
IMP
SceS000001869
GO:0046488 phosphatidylinositol metabolic
process		 P
IC
SpoSPAC824.02

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_3556

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga8359 ENSANGP00000014894
Ashbya gossypii (Ago) ago3713 AFR521W
Arabidopsis thaliana (Ath) ath15086 At3g27325.1
Caenorhabditis elegans (Cel) cel15681 T19B10.8
(CE06462;
WBGene00011835)
Candida glabrata (Cgl) cgl4052 CAGL0K12408g
Cryptococcus neoformans (Cne) cne1445 180.m00398
Dictyostelium discoideum (Ddi) ddi6416 DDB0218240
Debaryomyces hansenii (Dha) dha3109 DEHA0D18029g
Drosophila melanogaster (Dme) dme16613 CG3160-PA
(FBgn0029789)
Danio rerio (Dre) dre23485 ENSDARP00000015823
Danio rerio (Dre) dre23486 ENSDARP00000042622
Takifugu rubripes (Fru) fru31919 SINFRUP00000145416
Takifugu rubripes (Fru) fru31918 SINFRUP00000166466
Gallus gallus (Gga) gga21288 ENSGALP00000012920
Homo sapiens (Hsa) hsa19041 ENSP00000346809
(PGAP1)		 Q75T13-1
Kluyveromyces lactis (Kla) kla5200 KLLA0F25124g
Mus musculus (Mmu) mmu344 ENSMUSP00000075521
Neurospora crassa (Ncr) ncr7813 NCU08021.2
Oryza sativa (Osa) osa62049 6494.m00184
Rattus norvegicus (Rno) rno30038 ENSRNOP00000017967
(RGD:1303213)		 Q765A7
Saccharomyces cerevisiae (Sce) sce1978 YFL025C
(S000001869)
Schizosaccharomyces pombe (Spo) spo2161 SPAC824.02 Q9UT41
Yarrowia lipolytica (Yli) yli1149 YALI0B10043g
Yarrowia lipolytica (Yli) yli5506 YALI0F03927g
Yarrowia lipolytica (Yli) yli6607 YALI0F30767g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005783 endoplasmic reticulum C
IDA
AthAt3g27325
SceS000001869
SpoSPAC824.02
ISS
DmeFBgn0029789
GO:0005789 endoplasmic reticulum membrane C
IC
SpoSPAC824.02
GO:0005794 Golgi apparatus C
IDA
SpoSPAC824.02
GO:0005886 plasma membrane C
IDA
AthAt3g27325
GO:0016021 integral to membrane C
ISS
SceS000001869
GO:0004518 nuclease activity F
ISS
DmeFBgn0029789
GO:0042578 phosphoric ester hydrolase activity F
ISS
DmeFBgn0029789
GO:0050185 phosphatidylinositol deacylase
activity		 F
IGI
SceS000001869
ISS
SpoSPAC824.02
GO:0006505 GPI anchor metabolic process P
IGI
SceS000001869
ISS
SpoSPAC824.02
GO:0006621 protein retention in ER lumen P
IMP
SceS000001869
ISS
SpoSPAC824.02
GO:0006888 ER to Golgi vesicle-mediated transport P
IMP
SceS000001869
ISS
SpoSPAC824.02
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00011835
GO:0015798 myo-inositol transport P
ISS
DmeFBgn0029789
GO:0016050 vesicle organization P
IGI
SceS000001869
IMP
SceS000001869
ISS
SpoSPAC824.02
GO:0030433 ER-associated protein catabolic
process		 P
IMP
SceS000001869
GO:0046488 phosphatidylinositol metabolic
process		 P
IC
SpoSPAC824.02

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC824.02
(Q9UT41)		 YFL025C
(S000001869)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005783 endoplasmic reticulum C
IDA
SceS000001869
SpoSPAC824.02
GO:0005789 endoplasmic reticulum membrane C
IC
SpoSPAC824.02
GO:0005794 Golgi apparatus C
IDA
SpoSPAC824.02
GO:0016021 integral to membrane C
ISS
SceS000001869
GO:0050185 phosphatidylinositol deacylase
activity		 F
IGI
SceS000001869
ISS
SpoSPAC824.02
GO:0006505 GPI anchor metabolic process P
IGI
SceS000001869
ISS
SpoSPAC824.02
GO:0006621 protein retention in ER lumen P
IMP
SceS000001869
ISS
SpoSPAC824.02
GO:0006888 ER to Golgi vesicle-mediated transport P
IMP
SceS000001869
ISS
SpoSPAC824.02
GO:0016050 vesicle organization P
IGI
SceS000001869
IMP
SceS000001869
ISS
SpoSPAC824.02
GO:0030433 ER-associated protein catabolic
process		 P
IMP
SceS000001869
GO:0046488 phosphatidylinositol metabolic
process		 P
IC
SpoSPAC824.02

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GO info in one table:

s.khadayate@ucl.ac.uk