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Search term: YFL027C


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name GYP8
SGD link S000001867
Alternative ID YFL027C
Description GTPase-activating protein for yeast Rab family members; Ypt1p is the preferred in vitro substrate but also acts on Sec4p, Ypt31p and Ypt32p; involved in the regulation of ER to Golgi vesicle transport
Synonyms YFL027C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2595 -CDHYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Predicted GTPase activator protein

Species KOG link NCBI link UniProt link
Caenorhabditis elegans (Cel) CE20311 GI:17537531
Drosophila melanogaster (Dme) 7289454 GI:7289454
Homo sapiens (Hsa) Hs21389447 GI:17484376
Saccharomyces cerevisiae (Sce) YFL027c
(S000001867)
GI:16740526 P43570
Schizosaccharomyces pombe (Spo) SPBC651.03c GI:19112293 O94661


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005622 intracellular C
IDA
SceS000001867
GO:0005634 nucleus C
IDA
SpoSPBC651.03c
GO:0005783 endoplasmic reticulum C
IDA
SpoSPBC651.03c
GO:0005829 cytosol C
IDA
SpoSPBC651.03c
GO:0005097 Rab GTPase activator activity F
IGI
SceS000001867
IPI
SceS000001867
ISS
SceS000001867
SpoSPBC651.03c
GO:0000920 cytokinetic cell separation P
IGI
SpoSPBC651.03c
GO:0016192 vesicle-mediated transport P
IGI
SceS000001867
SpoSPBC651.03c
GO:0019953 sexual reproduction P
RCA
SceS000001867
GO:0032313 regulation of Rab GTPase activity P
ISS
SpoSPBC651.03c
GO:0035023 regulation of Rho protein signal
transduction
P
IGI
SpoSPBC651.03c

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
104198

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) GYP8
(S000001867)
GI:16740526 P43570
Kluyveromyces lactis (Kla) KLLA0F08789g GI:50310913
Eremothecium gossypii (Ego) AGOS_AFR154C GI:45198672


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005622 intracellular C
IDA
SceS000001867
GO:0005097 Rab GTPase activator activity F
IGI
SceS000001867
IPI
SceS000001867
ISS
SceS000001867
GO:0016192 vesicle-mediated transport P
IGI
SceS000001867
GO:0019953 sexual reproduction P
RCA
SceS000001867

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_3317

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Anopheles gambiae (Aga) aga10297 ENSANGP00000018258
Ashbya gossypii (Ago) ago3346 AFR154C
Caenorhabditis elegans (Cel) cel19726 Y54E2A.12
(CE37068;
WBGene00013196)
Candida glabrata (Cgl) cgl4054 CAGL0K12452g
Cryptococcus neoformans (Cne) cne1474 180.m00428
Dictyostelium discoideum (Ddi) ddi6147 DDB0218424
Debaryomyces hansenii (Dha) dha5013 DEHA0F14157g
Drosophila melanogaster (Dme) dme15662 CG17883-PA
Drosophila melanogaster (Dme) dme15663 CG17883-PB
Drosophila melanogaster (Dme) dme15664 CG17883-PC
Danio rerio (Dre) dre14137 ENSDARP00000045751
(zgc:110422)
Q1LXG3
Takifugu rubripes (Fru) fru29537 SINFRUP00000135151
Takifugu rubripes (Fru) fru29538 SINFRUP00000165862
Takifugu rubripes (Fru) fru31606 SINFRUP00000174109
Gallus gallus (Gga) gga12071 ENSGALP00000009992
(TBC1D20)
Gallus gallus (Gga) gga12072 ENSGALP00000009993
Homo sapiens (Hsa) hsa19633 ENSP00000246077
(TBC1D20)
Q96BZ9-3
Kluyveromyces lactis (Kla) kla4479 KLLA0F08789g
Mus musculus (Mmu) mmu15740 ENSMUSP00000028963
(MGI:1914481)
Q9D9I4
Neurospora crassa (Ncr) ncr5117 NCU05272.2
Rattus norvegicus (Rno) rno19978 ENSRNOP00000008713
(RGD:1303293)
Q6AXR1
Saccharomyces cerevisiae (Sce) sce1980 YFL027C
(S000001867)
Schizosaccharomyces pombe (Spo) spo4823 SPBC651.03c O94661
Yarrowia lipolytica (Yli) yli2703 YALI0C24332g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
MmuMGI:1914481
GO:0005622 intracellular C
IDA
SceS000001867
GO:0005634 nucleus C
IDA
SpoSPBC651.03c
GO:0005783 endoplasmic reticulum C
IDA
SpoSPBC651.03c
GO:0005829 cytosol C
IDA
SpoSPBC651.03c
GO:0003674 molecular_function F
ND
MmuMGI:1914481
GO:0005097 Rab GTPase activator activity F
IGI
SceS000001867
IPI
SceS000001867
ISS
SceS000001867
SpoSPBC651.03c
GO:0000920 cytokinetic cell separation P
IGI
SpoSPBC651.03c
GO:0008150 biological_process P
ND
MmuMGI:1914481
GO:0016192 vesicle-mediated transport P
IGI
SceS000001867
SpoSPBC651.03c
GO:0019953 sexual reproduction P
RCA
SceS000001867
GO:0032313 regulation of Rab GTPase activity P
ISS
SpoSPBC651.03c
GO:0035023 regulation of Rho protein signal
transduction
P
IGI
SpoSPBC651.03c

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPBC651.03c
(O94661)
YFL027C
(S000001867)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005622 intracellular C
IDA
SceS000001867
GO:0005634 nucleus C
IDA
SpoSPBC651.03c
GO:0005783 endoplasmic reticulum C
IDA
SpoSPBC651.03c
GO:0005829 cytosol C
IDA
SpoSPBC651.03c
GO:0005097 Rab GTPase activator activity F
IGI
SceS000001867
IPI
SceS000001867
ISS
SceS000001867
SpoSPBC651.03c
GO:0000920 cytokinetic cell separation P
IGI
SpoSPBC651.03c
GO:0016192 vesicle-mediated transport P
IGI
SceS000001867
SpoSPBC651.03c
GO:0019953 sexual reproduction P
RCA
SceS000001867
GO:0032313 regulation of Rab GTPase activity P
ISS
SpoSPBC651.03c
GO:0035023 regulation of Rho protein signal
transduction
P
IGI
SpoSPBC651.03c

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GO info in one table:

s.khadayate@ucl.ac.uk