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Search term: YFR019W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name FAB1
SGD link S000001915
Alternative ID YFR019W
Description 1-phosphatidylinositol-3-phosphate 5-kinase; vacuolar membrane kinase that generates phosphatidylinositol (3,5)P2, which is involved in vacuolar sorting and homeostasis
Synonyms YFR019W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0230 ACDHYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Phosphatidylinositol-4-phosphate 5-kinase and related FYVE finger-containing proteins

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g34260 GI:15218566
Arabidopsis thaliana (Ath) At1g71010 GI:15223312
Arabidopsis thaliana (Ath) At3g14270 GI:15231820
Arabidopsis thaliana (Ath) At4g33240 GI:15234121
Caenorhabditis elegans (Cel) CE18979 GI:17569149
Drosophila melanogaster (Dme) 7302711 GI:20130093
Homo sapiens (Hsa) Hs14729948 GI:14729948
Homo sapiens (Hsa) Hs20535111 GI:20535111
Saccharomyces cerevisiae (Sce) YFR019w
(S000001915)		 GI:14318541 P34756
Schizosaccharomyces pombe (Spo) SPBC6B1.11c GI:19112882
Arabidopsis thaliana (Ath) At1g34260 GI:15218566
Arabidopsis thaliana (Ath) At1g71010 GI:15223312
Arabidopsis thaliana (Ath) At3g14270 GI:15231820
Arabidopsis thaliana (Ath) At4g33240 GI:15234121
Caenorhabditis elegans (Cel) CE18979 GI:17569149
Drosophila melanogaster (Dme) 7302711 GI:20130093
Homo sapiens (Hsa) Hs14729948 GI:14729948
Homo sapiens (Hsa) Hs20535111 GI:20535111
Saccharomyces cerevisiae (Sce) YFR019w
(S000001915)		 GI:14318541 P34756
Schizosaccharomyces pombe (Spo) SPBC6B1.11c GI:19112882
Arabidopsis thaliana (Ath) At1g34260 GI:15218566
Arabidopsis thaliana (Ath) At1g71010 GI:15223312
Arabidopsis thaliana (Ath) At3g14270 GI:15231820
Arabidopsis thaliana (Ath) At4g33240 GI:15234121
Caenorhabditis elegans (Cel) CE18979 GI:17569149
Drosophila melanogaster (Dme) 7302711 GI:20130093
Homo sapiens (Hsa) Hs14729948 GI:14729948
Homo sapiens (Hsa) Hs20535111 GI:20535111
Saccharomyces cerevisiae (Sce) YFR019w
(S000001915)		 GI:14318541 P34756
Schizosaccharomyces pombe (Spo) SPBC6B1.11c GI:19112882


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000329 fungal-type vacuole membrane C
IDA
SceS000001915
GO:0005575 cellular_component C
ND
AthAt1g71010
At1g34260
GO:0005739 mitochondrion C
IDA
AthAt3g14270
SceS000001915
GO:0010008 endosome membrane C
IDA
SceS000001915
GO:0070772 PAS complex C
IDA
SceS000001915
IPI
SceS000001915
GO:0000285 1-phosphatidylinositol-3-phosphate 5-kinase
activity		 F
IDA
SceS000001915
IMP
SceS000001915
ISS
AthAt4g33240
At3g14270
GO:0008270 zinc ion binding F
ISS
AthAt4g33240
At3g14270
GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase
activity		 F
ISS
AthAt1g34260
At3g14270
At4g33240
At1g71010
GO:0032266 phosphatidylinositol-3-phosphate
binding		 F
IDA
SceS000001915
GO:0035091 phosphoinositide binding F
ISS
AthAt3g14270
GO:0007033 vacuole organization P
IGI
AthAt4g33240
At3g14270
GO:0007165 signal transduction P
ISS
AthAt3g14270
GO:0009555 pollen development P
IGI
AthAt4g33240
At3g14270
GO:0046854 phosphoinositide phosphorylation P
IDA
SceS000001915
IMP
SceS000001915
GO:0050801 ion homeostasis P
RCA
SceS000001915

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
84881

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) FAB1
(S000001915)		 GI:14318541 P34756
Kluyveromyces lactis (Kla) KLLA0D04598g GI:50306587


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000329 fungal-type vacuole membrane C
IDA
SceS000001915
GO:0005739 mitochondrion C
IDA
SceS000001915
GO:0010008 endosome membrane C
IDA
SceS000001915
GO:0070772 PAS complex C
IDA
SceS000001915
IPI
SceS000001915
GO:0000285 1-phosphatidylinositol-3-phosphate 5-kinase
activity		 F
IDA
SceS000001915
IMP
SceS000001915
GO:0032266 phosphatidylinositol-3-phosphate
binding		 F
IDA
SceS000001915
GO:0046854 phosphoinositide phosphorylation P
IDA
SceS000001915
IMP
SceS000001915
GO:0050801 ion homeostasis P
RCA
SceS000001915

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1914

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga606 ENSANGP00000003760
Ashbya gossypii (Ago) ago2690 AER188C
Arabidopsis thaliana (Ath) ath6386 At1g71010.1
Arabidopsis thaliana (Ath) ath13624 At3g14270.1
Arabidopsis thaliana (Ath) ath21438 At4g33240.1
Caenorhabditis elegans (Cel) cel16689 VF11C1L.1
(CE40822;
WBGene00004089)
Candida glabrata (Cgl) cgl3968 CAGL0K10384g
Cryptococcus neoformans (Cne) cne963 163.m06431
Dictyostelium discoideum (Ddi) ddi5049 DDB0204693
Debaryomyces hansenii (Dha) dha6131 DEHA0G09680g
Drosophila melanogaster (Dme) dme5732 CG6355-PA
(FBgn0028741)
Drosophila melanogaster (Dme) dme5733 CG6355-PB
(FBgn0028741)
Danio rerio (Dre) dre23695 ENSDARP00000018509
Takifugu rubripes (Fru) fru32248 SINFRUP00000143865
Takifugu rubripes (Fru) fru32250 SINFRUP00000173899
Takifugu rubripes (Fru) fru32249 SINFRUP00000175401
Gallus gallus (Gga) gga21412 ENSGALP00000014352
Gallus gallus (Gga) gga21413 ENSGALP00000014353
Gallus gallus (Gga) gga21411 ENSGALP00000014354
(PIP5K3)
Homo sapiens (Hsa) hsa19201 ENSP00000264380
(PIKFYVE)		 Q9Y2I7
Kluyveromyces lactis (Kla) kla2266 KLLA0D04598g
Mus musculus (Mmu) mmu473 ENSMUSP00000076113
Mus musculus (Mmu) mmu474 ENSMUSP00000079926
(MGI:1335106)
Neurospora crassa (Ncr) ncr2025 NCU02083.2
Oryza sativa (Osa) osa1205 1069.m00068
Oryza sativa (Osa) osa16147 3064.m00125
Oryza sativa (Osa) osa44678 5621.m00186
Oryza sativa (Osa) osa51114 5966.m00116
Oryza sativa (Osa) osa53045 6122.m00106
Oryza sativa (Osa) osa64893 6722.m00173
Rattus norvegicus (Rno) rno30169 ENSRNOP00000020447
(GI:316457)
Saccharomyces cerevisiae (Sce) sce2045 YFR019W
(S000001915)
Schizosaccharomyces pombe (Spo) spo4059 SPBC3E7.01 O59722
Yarrowia lipolytica (Yli) yli5065 YALI0E29161g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000329 fungal-type vacuole membrane C
IDA
SceS000001915
ISS
SpoSPBC3E7.01
GO:0005575 cellular_component C
ND
AthAt1g71010
GO:0005739 mitochondrion C
IDA
AthAt3g14270
SceS000001915
GO:0005768 endosome C
IDA
DmeFBgn0028741
GO:0005829 cytosol C
IDA
MmuMGI:1335106
GO:0010008 endosome membrane C
IDA
SceS000001915
GO:0012506 vesicle membrane C
IDA
MmuMGI:1335106
ISS
DmeFBgn0028741
GO:0031410 cytoplasmic vesicle C
IDA
MmuMGI:1335106
GO:0070772 PAS complex C
IDA
SceS000001915
IPI
SceS000001915
GO:0000285 1-phosphatidylinositol-3-phosphate 5-kinase
activity		 F
IDA
SceS000001915
SpoSPBC3E7.01
IGI
SpoSPBC3E7.01
IMP
DmeFBgn0028741
SceS000001915
ISS
AthAt4g33240
At3g14270
GO:0005515 protein binding F
IPI
MmuMGI:1335106
GO:0005524 ATP binding F
ISS
SpoSPBC3E7.01
GO:0008270 zinc ion binding F
IDA
MmuMGI:1335106
ISS
AthAt4g33240
At3g14270
DmeFBgn0028741
GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase
activity		 F
IDA
MmuMGI:1335106
ISS
AthAt3g14270
At4g33240
At1g71010
DmeFBgn0028741
NAS
DmeFBgn0028741
GO:0032266 phosphatidylinositol-3-phosphate
binding		 F
IDA
SceS000001915
ISS
CelWBGene00004089
SpoSPBC3E7.01
GO:0035091 phosphoinositide binding F
ISS
AthAt3g14270
GO:0000750 pheromone-dependent signal transduction involved
in conjugation with cellular fusion		 P
IMP
SpoSPBC3E7.01
GO:0006886 intracellular protein transport P
IC
SpoSPBC3E7.01
GO:0006995 cellular response to nitrogen starvation P
IMP
SpoSPBC3E7.01
GO:0007033 vacuole organization P
IGI
AthAt4g33240
At3g14270
ISS
SpoSPBC3E7.01
GO:0007165 signal transduction P
ISS
AthAt3g14270
GO:0008333 endosome to lysosome transport P
IMP
DmeFBgn0028741
GO:0009555 pollen development P
IGI
AthAt4g33240
At3g14270
GO:0016192 vesicle-mediated transport P
IGI
SpoSPBC3E7.01
GO:0016310 phosphorylation P
NAS
DmeFBgn0028741
GO:0023034 intracellular signaling pathway P
IDA
MmuMGI:1335106
ISS
DmeFBgn0028741
GO:0046488 phosphatidylinositol metabolic
process		 P
IC
SpoSPBC3E7.01
GO:0046854 phosphoinositide phosphorylation P
IDA
MmuMGI:1335106
SceS000001915
SpoSPBC3E7.01
IMP
DmeFBgn0028741
SceS000001915
GO:0050801 ion homeostasis P
RCA
SceS000001915

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC3E7.01
(O59722)		 YFR019W
(S000001915)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000329 fungal-type vacuole membrane C
IDA
SceS000001915
ISS
SpoSPBC3E7.01
GO:0005739 mitochondrion C
IDA
SceS000001915
GO:0010008 endosome membrane C
IDA
SceS000001915
GO:0070772 PAS complex C
IDA
SceS000001915
IPI
SceS000001915
GO:0000285 1-phosphatidylinositol-3-phosphate 5-kinase
activity		 F
IDA
SceS000001915
SpoSPBC3E7.01
IGI
SpoSPBC3E7.01
IMP
SceS000001915
GO:0005524 ATP binding F
ISS
SpoSPBC3E7.01
GO:0032266 phosphatidylinositol-3-phosphate
binding		 F
IDA
SceS000001915
ISS
SpoSPBC3E7.01
GO:0000750 pheromone-dependent signal transduction involved
in conjugation with cellular fusion		 P
IMP
SpoSPBC3E7.01
GO:0006886 intracellular protein transport P
IC
SpoSPBC3E7.01
GO:0006995 cellular response to nitrogen starvation P
IMP
SpoSPBC3E7.01
GO:0007033 vacuole organization P
ISS
SpoSPBC3E7.01
GO:0016192 vesicle-mediated transport P
IGI
SpoSPBC3E7.01
GO:0046488 phosphatidylinositol metabolic
process		 P
IC
SpoSPBC3E7.01
GO:0046854 phosphoinositide phosphorylation P
IDA
SceS000001915
SpoSPBC3E7.01
IMP
SceS000001915
GO:0050801 ion homeostasis P
RCA
SceS000001915

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Search for gene by ID or name:

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GO info in one table:

s.khadayate@ucl.ac.uk