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Search term: YFR031C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name SMC2
SGD link S000001927
Alternative ID YFR031C
Description Subunit of the condensin complex; essential SMC chromosomal ATPase family member that forms a complex with Smc4p to form the active ATPase; Smc2p/Smc4p complex binds DNA; required for clustering of tRNA genes at the nucleolus
Synonyms YFR031C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0933 ACDHYPE

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSINGCELLULAR PROCESSES AND SIGNALING Structural maintenance of chromosome protein 2 (chromosome condensation complex Condensin, subunit E)

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At3g47460 GI:15232802
Arabidopsis thaliana (Ath) At5g62410 GI:15241831
Caenorhabditis elegans (Cel) CE18083
(WBGene00003367)		 GI:17535279 Q09591
Drosophila melanogaster (Dme) 7303132
(FBgn0027783)		 GI:19922276 Q7KK96
Homo sapiens (Hsa) Hs5453591 GI:5453591
Saccharomyces cerevisiae (Sce) YFR031c
(S000001927)		 GI:14318554 P38989
Schizosaccharomyces pombe (Spo) SPBP4H10.06c GI:19112972 P41003
Encephalitozoon cuniculi (Ecu) ECU01g1160 GI:19075129
Arabidopsis thaliana (Ath) At3g47460 GI:15232802
Arabidopsis thaliana (Ath) At5g62410 GI:15241831
Caenorhabditis elegans (Cel) CE18083
(WBGene00003367)		 GI:17535279 Q09591
Drosophila melanogaster (Dme) 7303132
(FBgn0027783)		 GI:19922276 Q7KK96
Homo sapiens (Hsa) Hs5453591 GI:5453591
Saccharomyces cerevisiae (Sce) YFR031c
(S000001927)		 GI:14318554 P38989
Schizosaccharomyces pombe (Spo) SPBP4H10.06c GI:19112972 P41003
Encephalitozoon cuniculi (Ecu) ECU01g1160 GI:19075129


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000775 chromosome, centromeric region C
IDA
CelWBGene00003367
GO:0000793 condensed chromosome C
IDA
CelWBGene00003367
GO:0000796 condensin complex C
IDA
SpoSPBP4H10.06c
ISS
AthAt5g62410
DmeFBgn0027783
NAS
DmeFBgn0027783
GO:0000799 nuclear condensin complex C
IPI
SceS000001927
ISS
SceS000001927
TAS
SceS000001927
GO:0000939 inner kinetochore of condensed
chromosome		 C
IDA
SpoSPBP4H10.06c
GO:0005634 nucleus C
IDA
SpoSPBP4H10.06c
GO:0005730 nucleolus C
IDA
SpoSPBP4H10.06c
GO:0005737 cytoplasm C
IDA
SpoSPBP4H10.06c
GO:0005739 mitochondrion C
IDA
SceS000001927
GO:0005875 microtubule associated complex C
IDA
DmeFBgn0027783
GO:0008278 cohesin complex C
ISS
DmeFBgn0027783
GO:0046536 dosage compensation complex C
IPI
CelWBGene00003367
GO:0000217 DNA secondary structure binding F
IDA
SceS000001927
GO:0003677 DNA binding F
ISS
DmeFBgn0027783
GO:0003680 AT DNA binding F
IDA
SceS000001927
GO:0003690 double-stranded DNA binding F
IDA
SceS000001927
GO:0005215 transporter activity F
ISS
AthAt5g62410
At3g47460
GO:0016887 ATPase activity F
IDA
SceS000001927
ISS
SpoSPBP4H10.06c
GO:0030528 transcription regulator activity F
TAS
CelWBGene00003367
GO:0000070 mitotic sister chromatid segregation P
IMP
CelWBGene00003367
TAS
SceS000001927
GO:0002119 nematode larval development P
IMP
CelWBGene00003367
GO:0006200 ATP catabolic process P
ISS
SpoSPBP4H10.06c
GO:0007052 mitotic spindle organization P
IMP
DmeFBgn0027783
GO:0007062 sister chromatid cohesion P
ISS
DmeFBgn0027783
GO:0007076 mitotic chromosome condensation P
IMP
CelWBGene00003367
DmeFBgn0027783
SceS000001927
SpoSPBP4H10.06c
TAS
SceS000001927
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00003367
GO:0034500 rDNA separation P
IMP
SpoSPBP4H10.06c
GO:0040039 inductive cell migration P
IMP
CelWBGene00003367
GO:0042464 dosage compensation, by hypoactivation of X
chromosome		 P
IMP
CelWBGene00003367
GO:0070058 tRNA gene clustering P
IMP
SceS000001927

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
4705

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) SMC2 GI:110347420
Pan troglodytes (Ptr) SMC2 GI:114625954
Canis familiaris (Cfa) SMC2 GI:73971498
Mus musculus (Mmu) Smc2
(MGI:106067)		 GI:62990166 Q3TT08
Rattus norvegicus (Rno) Smc2 GI:34868391
Gallus gallus (Gga) SMC2 GI:45382553
Drosophila melanogaster (Dme) SMC2
(FBgn0027783)		 GI:19922276 Q7KK96
Anopheles gambiae (Aga) AgaP_AGAP011425 GI:57913907
Schizosaccharomyces pombe (Spo) cut14
(SPBP4H10.06c)		 GI:19112972 P41003
Saccharomyces cerevisiae (Sce) SMC2
(S000001927)		 GI:14318554 P38989
Kluyveromyces lactis (Kla) KLLA0D16005g GI:50307571
Eremothecium gossypii (Ego) AGOS_AGR236W GI:45201332
Magnaporthe grisea (Mgr) MGG_07098 GI:39971565
Neurospora crassa (Ncr) NCU07679.1 GI:32415814
Arabidopsis thaliana (Ath) SMC2 GI:15241831
Arabidopsis thaliana (Ath) ATSMC2 GI:15232802
Oryza sativa (Osa) Os01g0904400 GI:115441687
Plasmodium falciparum (Pfa) MAL13P1.96 GI:124513128


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000228 nuclear chromosome C
IDA
HsaSMC2
GO:0000793 condensed chromosome C
IDA
HsaSMC2
GO:0000796 condensin complex C
IDA
HsaSMC2
SpoSPBP4H10.06c
ISS
DmeFBgn0027783
NAS
DmeFBgn0027783
GO:0000799 nuclear condensin complex C
IPI
SceS000001927
ISS
SceS000001927
TAS
SceS000001927
GO:0000939 inner kinetochore of condensed
chromosome		 C
IDA
SpoSPBP4H10.06c
GO:0005575 cellular_component C
ND
MmuMGI:106067
GO:0005634 nucleus C
IDA
HsaSMC2
SpoSPBP4H10.06c
GO:0005730 nucleolus C
IDA
SpoSPBP4H10.06c
GO:0005737 cytoplasm C
IDA
HsaSMC2
SpoSPBP4H10.06c
GO:0005739 mitochondrion C
IDA
SceS000001927
GO:0005875 microtubule associated complex C
IDA
DmeFBgn0027783
GO:0008278 cohesin complex C
ISS
DmeFBgn0027783
GO:0000217 DNA secondary structure binding F
IDA
SceS000001927
GO:0003677 DNA binding F
ISS
DmeFBgn0027783
GO:0003680 AT DNA binding F
IDA
SceS000001927
GO:0003690 double-stranded DNA binding F
IDA
SceS000001927
GO:0005215 transporter activity F
ISS
AthATSMC2
GO:0005515 protein binding F
IPI
HsaSMC2
MmuMGI:106067
GO:0016887 ATPase activity F
IDA
SceS000001927
ISS
SpoSPBP4H10.06c
GO:0046982 protein heterodimerization activity F
IPI
HsaSMC2
GO:0000070 mitotic sister chromatid segregation P
ISS
PfaMAL13P1.96
TAS
SceS000001927
GO:0006200 ATP catabolic process P
ISS
SpoSPBP4H10.06c
GO:0007052 mitotic spindle organization P
IMP
DmeFBgn0027783
GO:0007062 sister chromatid cohesion P
ISS
DmeFBgn0027783
GO:0007076 mitotic chromosome condensation P
IDA
HsaSMC2
IMP
DmeFBgn0027783
SceS000001927
SpoSPBP4H10.06c
TAS
SceS000001927
GO:0008150 biological_process P
ND
MmuMGI:106067
GO:0034500 rDNA separation P
IMP
SpoSPBP4H10.06c
GO:0044403 symbiosis, encompassing mutualism through
parasitism		 P
IDA
HsaSMC2
GO:0070058 tRNA gene clustering P
IMP
SceS000001927

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1035

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga8515 ENSANGP00000012139
Anopheles gambiae (Aga) aga8516 ENSANGP00000029709
Ashbya gossypii (Ago) ago4547 AGR236W
Arabidopsis thaliana (Ath) ath16033 At3g47460.1
Arabidopsis thaliana (Ath) ath28350 At5g62410.1
Caenorhabditis elegans (Cel) cel12978 M106.1
(CE18083;
WBGene00003367)
Candida glabrata (Cgl) cgl883 CAGL0D05258g
Cryptococcus neoformans (Cne) cne4498 177.m03259
Dictyostelium discoideum (Ddi) ddi12921 DDB0219933
Debaryomyces hansenii (Dha) dha1346 DEHA0B15246g
Debaryomyces hansenii (Dha) dha1347 DEHA0B15268g
Drosophila melanogaster (Dme) dme5151 CG10212-PA
(FBgn0027783)
Danio rerio (Dre) dre396 ENSDARP00000005075
(zgc:55326)		 Q803Y7
Danio rerio (Dre) dre397 ENSDARP00000027519
Encephalitozoon cuniculi (Ecu) ecu1766 19075129
Takifugu rubripes (Fru) fru8952 SINFRUP00000151446
Gallus gallus (Gga) gga28054 ENSGALP00000025260
(SMC2)		 Q90988
Homo sapiens (Hsa) hsa31660 ENSP00000286398
(SMC2)		 O95347-1
Homo sapiens (Hsa) hsa31661 ENSP00000306152
(SMC2)		 O95347-2
Kluyveromyces lactis (Kla) kla2764 KLLA0D16005g
Mus musculus (Mmu) mmu18140 ENSMUSP00000029993
Neurospora crassa (Ncr) ncr7477 NCU07679.2
Oryza sativa (Osa) osa32215 4401.m00166
Plasmodium falciparum (Pfa) pfa4327 MAL13P1.96
Rattus norvegicus (Rno) rno23132 ENSRNOP00000029830
(RGD:1305227)
Saccharomyces cerevisiae (Sce) sce2057 YFR031C
(S000001927)
Schizosaccharomyces pombe (Spo) spo3841 SPBP4H10.06c P41003
Yarrowia lipolytica (Yli) yli6383 YALI0F24783g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000775 chromosome, centromeric region C
IDA
CelWBGene00003367
GO:0000793 condensed chromosome C
IDA
CelWBGene00003367
GO:0000796 condensin complex C
IDA
SpoSPBP4H10.06c
ISS
AthAt5g62410
DmeFBgn0027783
NAS
DmeFBgn0027783
GO:0000799 nuclear condensin complex C
IPI
SceS000001927
ISS
SceS000001927
TAS
SceS000001927
GO:0000939 inner kinetochore of condensed
chromosome		 C
IDA
SpoSPBP4H10.06c
GO:0005634 nucleus C
IDA
SpoSPBP4H10.06c
GO:0005730 nucleolus C
IDA
SpoSPBP4H10.06c
GO:0005737 cytoplasm C
IDA
SpoSPBP4H10.06c
GO:0005739 mitochondrion C
IDA
SceS000001927
GO:0005875 microtubule associated complex C
IDA
DmeFBgn0027783
GO:0008278 cohesin complex C
ISS
DmeFBgn0027783
GO:0046536 dosage compensation complex C
IPI
CelWBGene00003367
GO:0000217 DNA secondary structure binding F
IDA
SceS000001927
GO:0003677 DNA binding F
ISS
DmeFBgn0027783
GO:0003680 AT DNA binding F
IDA
SceS000001927
GO:0003690 double-stranded DNA binding F
IDA
SceS000001927
GO:0005215 transporter activity F
ISS
AthAt5g62410
At3g47460
GO:0016887 ATPase activity F
IDA
SceS000001927
ISS
SpoSPBP4H10.06c
GO:0030528 transcription regulator activity F
TAS
CelWBGene00003367
GO:0000070 mitotic sister chromatid segregation P
IMP
CelWBGene00003367
ISS
PfaMAL13P1.96
TAS
SceS000001927
GO:0002119 nematode larval development P
IMP
CelWBGene00003367
GO:0006200 ATP catabolic process P
ISS
SpoSPBP4H10.06c
GO:0007052 mitotic spindle organization P
IMP
DmeFBgn0027783
GO:0007062 sister chromatid cohesion P
ISS
DmeFBgn0027783
GO:0007076 mitotic chromosome condensation P
IMP
CelWBGene00003367
DmeFBgn0027783
SceS000001927
SpoSPBP4H10.06c
TAS
SceS000001927
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00003367
GO:0034500 rDNA separation P
IMP
SpoSPBP4H10.06c
GO:0040039 inductive cell migration P
IMP
CelWBGene00003367
GO:0042464 dosage compensation, by hypoactivation of X
chromosome		 P
IMP
CelWBGene00003367
GO:0070058 tRNA gene clustering P
IMP
SceS000001927

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBP4H10.06c
(P41003)		 YFR031C
(S000001927)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000796 condensin complex C
IDA
SpoSPBP4H10.06c
GO:0000799 nuclear condensin complex C
IPI
SceS000001927
ISS
SceS000001927
TAS
SceS000001927
GO:0000939 inner kinetochore of condensed
chromosome		 C
IDA
SpoSPBP4H10.06c
GO:0005634 nucleus C
IDA
SpoSPBP4H10.06c
GO:0005730 nucleolus C
IDA
SpoSPBP4H10.06c
GO:0005737 cytoplasm C
IDA
SpoSPBP4H10.06c
GO:0005739 mitochondrion C
IDA
SceS000001927
GO:0000217 DNA secondary structure binding F
IDA
SceS000001927
GO:0003680 AT DNA binding F
IDA
SceS000001927
GO:0003690 double-stranded DNA binding F
IDA
SceS000001927
GO:0016887 ATPase activity F
IDA
SceS000001927
ISS
SpoSPBP4H10.06c
GO:0000070 mitotic sister chromatid segregation P
TAS
SceS000001927
GO:0006200 ATP catabolic process P
ISS
SpoSPBP4H10.06c
GO:0007076 mitotic chromosome condensation P
IMP
SceS000001927
SpoSPBP4H10.06c
TAS
SceS000001927
GO:0034500 rDNA separation P
IMP
SpoSPBP4H10.06c
GO:0070058 tRNA gene clustering P
IMP
SceS000001927

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