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Search term: YGL003C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name CDH1
SGD link S000002971
Alternative ID YGL003C
Description Cell-cycle regulated activator of the anaphase-promoting complex/cyclosome (APC/C), which directs ubiquitination of cyclins resulting in mitotic exit; targets the APC/C to specific substrates including Cdc20p, Ase1p, Cin8p and Fin1p
Synonyms YGL003C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0305 ACDHYPE

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALINGCELLULAR PROCESSES AND SIGNALING Anaphase promoting complex, Cdc20, Cdh1, and Ama1 subunits

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At4g11920 GI:15234350
Arabidopsis thaliana (Ath) At4g22910 GI:15235859
Arabidopsis thaliana (Ath) At4g33260 GI:15234125
Arabidopsis thaliana (Ath) At4g33270 GI:15234128
Arabidopsis thaliana (Ath) At5g13840 GI:15240729
Arabidopsis thaliana (Ath) At5g26900 GI:15240403
Arabidopsis thaliana (Ath) At5g27080 GI:15240441
Arabidopsis thaliana (Ath) At5g27570 GI:15240985
Arabidopsis thaliana (Ath) At5g27940 GI:15241103
Caenorhabditis elegans (Cel) CE01695
(WBGene00001510)		 GI:17538129 Q09649
Caenorhabditis elegans (Cel) CE26338
(WBGene00001511)		 GI:17537825 Q09373
Drosophila melanogaster (Dme) 7290520 GI:7290520
Drosophila melanogaster (Dme) 7291689 GI:19922858
Drosophila melanogaster (Dme) 7297154
(FBgn0000351)		 GI:17647275
Drosophila melanogaster (Dme) 7298293
(FBgn0001086)		 GI:17137788
Homo sapiens (Hsa) Hs22050287 GI:22050287
Homo sapiens (Hsa) Hs22050291 GI:22050291
Homo sapiens (Hsa) Hs4557437 GI:4557437
Homo sapiens (Hsa) Hs7705377 GI:7705377
Saccharomyces cerevisiae (Sce) YGL003c
(S000002971)		 GI:6321435 P53197
Saccharomyces cerevisiae (Sce) YGL116w
(S000003084)		 GI:6321322 P26309
Saccharomyces cerevisiae (Sce) YGR225w
(S000003457)		 GI:6681847
Schizosaccharomyces pombe (Spo) SPAC13G6.08 GI:19113746 Q09786
Schizosaccharomyces pombe (Spo) SPAC144.13c GI:19115586 O13286
Schizosaccharomyces pombe (Spo) SPAC821.08c GI:19114073 P78972
Schizosaccharomyces pombe (Spo) SPBC1198.12 GI:19111873 O94423
Schizosaccharomyces pombe (Spo) SPCC1620.04c GI:19075962 O94411
Encephalitozoon cuniculi (Ecu) ECU03g1520 GI:19173109 Q8SVZ6
Encephalitozoon cuniculi (Ecu) ECU04g1250 GI:19074203 Q8SS21
Arabidopsis thaliana (Ath) At4g11920 GI:15234350
Arabidopsis thaliana (Ath) At4g22910 GI:15235859
Arabidopsis thaliana (Ath) At4g33260 GI:15234125
Arabidopsis thaliana (Ath) At4g33270 GI:15234128
Arabidopsis thaliana (Ath) At5g13840 GI:15240729
Arabidopsis thaliana (Ath) At5g26900 GI:15240403
Arabidopsis thaliana (Ath) At5g27080 GI:15240441
Arabidopsis thaliana (Ath) At5g27570 GI:15240985
Arabidopsis thaliana (Ath) At5g27940 GI:15241103
Caenorhabditis elegans (Cel) CE01695
(WBGene00001510)		 GI:17538129 Q09649
Caenorhabditis elegans (Cel) CE26338
(WBGene00001511)		 GI:17537825 Q09373
Drosophila melanogaster (Dme) 7290520 GI:7290520
Drosophila melanogaster (Dme) 7291689 GI:19922858
Drosophila melanogaster (Dme) 7297154
(FBgn0000351)		 GI:17647275
Drosophila melanogaster (Dme) 7298293
(FBgn0001086)		 GI:17137788
Homo sapiens (Hsa) Hs22050287 GI:22050287
Homo sapiens (Hsa) Hs22050291 GI:22050291
Homo sapiens (Hsa) Hs4557437 GI:4557437
Homo sapiens (Hsa) Hs7705377 GI:7705377
Saccharomyces cerevisiae (Sce) YGL003c
(S000002971)		 GI:6321435 P53197
Saccharomyces cerevisiae (Sce) YGL116w
(S000003084)		 GI:6321322 P26309
Saccharomyces cerevisiae (Sce) YGR225w
(S000003457)		 GI:6681847
Schizosaccharomyces pombe (Spo) SPAC13G6.08 GI:19113746 Q09786
Schizosaccharomyces pombe (Spo) SPAC144.13c GI:19115586 O13286
Schizosaccharomyces pombe (Spo) SPAC821.08c GI:19114073 P78972
Schizosaccharomyces pombe (Spo) SPBC1198.12 GI:19111873 O94423
Schizosaccharomyces pombe (Spo) SPCC1620.04c GI:19075962 O94411
Encephalitozoon cuniculi (Ecu) ECU03g1520 GI:19173109 Q8SVZ6
Encephalitozoon cuniculi (Ecu) ECU04g1250 GI:19074203 Q8SS21
Arabidopsis thaliana (Ath) At4g11920 GI:15234350
Arabidopsis thaliana (Ath) At4g22910 GI:15235859
Arabidopsis thaliana (Ath) At4g33260 GI:15234125
Arabidopsis thaliana (Ath) At4g33270 GI:15234128
Arabidopsis thaliana (Ath) At5g13840 GI:15240729
Arabidopsis thaliana (Ath) At5g26900 GI:15240403
Arabidopsis thaliana (Ath) At5g27080 GI:15240441
Arabidopsis thaliana (Ath) At5g27570 GI:15240985
Arabidopsis thaliana (Ath) At5g27940 GI:15241103
Caenorhabditis elegans (Cel) CE01695
(WBGene00001510)		 GI:17538129 Q09649
Caenorhabditis elegans (Cel) CE26338
(WBGene00001511)		 GI:17537825 Q09373
Drosophila melanogaster (Dme) 7290520 GI:7290520
Drosophila melanogaster (Dme) 7291689 GI:19922858
Drosophila melanogaster (Dme) 7297154
(FBgn0000351)		 GI:17647275
Drosophila melanogaster (Dme) 7298293
(FBgn0001086)		 GI:17137788
Homo sapiens (Hsa) Hs22050287 GI:22050287
Homo sapiens (Hsa) Hs22050291 GI:22050291
Homo sapiens (Hsa) Hs4557437 GI:4557437
Homo sapiens (Hsa) Hs7705377 GI:7705377
Saccharomyces cerevisiae (Sce) YGL003c
(S000002971)		 GI:6321435 P53197
Saccharomyces cerevisiae (Sce) YGL116w
(S000003084)		 GI:6321322 P26309
Saccharomyces cerevisiae (Sce) YGR225w
(S000003457)		 GI:6681847
Schizosaccharomyces pombe (Spo) SPAC13G6.08 GI:19113746 Q09786
Schizosaccharomyces pombe (Spo) SPAC144.13c GI:19115586 O13286
Schizosaccharomyces pombe (Spo) SPAC821.08c GI:19114073 P78972
Schizosaccharomyces pombe (Spo) SPBC1198.12 GI:19111873 O94423
Schizosaccharomyces pombe (Spo) SPCC1620.04c GI:19075962 O94411
Encephalitozoon cuniculi (Ecu) ECU03g1520 GI:19173109 Q8SVZ6
Encephalitozoon cuniculi (Ecu) ECU04g1250 GI:19074203 Q8SS21


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000776 kinetochore C
IDA
DmeFBgn0001086
TAS
DmeFBgn0001086
GO:0000778 condensed nuclear chromosome kinetochore C
IDA
SpoSPAC821.08c
GO:0000793 condensed chromosome C
IDA
CelWBGene00001511
GO:0005575 cellular_component C
ND
AthAt5g27940
GO:0005634 nucleus C
IDA
AthAt4g11920
SceS000002971
SpoSPAC144.13c
SPBC1198.12
SPCC1620.04c
SPAC821.08c
GO:0005680 anaphase-promoting complex C
IPI
SceS000002971
S000003084
S000003457
GO:0005737 cytoplasm C
IDA
AthAt4g11920
CelWBGene00001511
DmeFBgn0000351
SceS000002971
TAS
DmeFBgn0001086
GO:0005813 centrosome C
IDA
DmeFBgn0001086
TAS
DmeFBgn0001086
GO:0005816 spindle pole body C
IDA
SpoSPAC821.08c
GO:0005819 spindle C
IDA
DmeFBgn0001086
SpoSPAC821.08c
GO:0005834 heterotrimeric G-protein complex C
ISS
AthAt4g22910
At4g11920
At5g27570
At4g33260
At4g33270
At5g13840
At5g27080
At5g26900
GO:0032153 cell division site C
IDA
SpoSPAC821.08c
GO:0033597 mitotic checkpoint complex C
IDA
SceS000003084
SpoSPAC821.08c
IPI
SceS000003084
GO:0043234 protein complex C
NAS
SpoSPAC13G6.08
SPAC144.13c
SPBC1198.12
SPCC1620.04c
GO:0080008 CUL4 RING ubiquitin ligase complex C
ISS
AthAt5g27570
At5g27080
GO:0003674 molecular_function F
ND
AthAt5g27940
SpoSPAC13G6.08
SPAC144.13c
SPCC1620.04c
GO:0004842 ubiquitin-protein ligase activity F
IDA
SceS000003084
S000002971
GO:0004871 signal transducer activity F
ISS
AthAt5g27570
At4g33260
At4g22910
At4g33270
At5g27080
At4g11920
At5g26900
At5g13840
GO:0005515 protein binding F
IPI
SpoSPBC1198.12
SPAC821.08c
GO:0008047 enzyme activator activity F
IMP
SceS000003457
IPI
SceS000003457
GO:0010997 anaphase-promoting complex binding F
IPI
DmeFBgn0000351
SpoSPAC821.08c
GO:0030674 protein binding, bridging F
IPI
SceS000002971
S000003084
GO:0000003 reproduction P
IMP
CelWBGene00001511
GO:0000022 mitotic spindle elongation P
TAS
SceS000002971
S000003084
GO:0000070 mitotic sister chromatid segregation P
IGI
SpoSPAC821.08c
TAS
SceS000002971
S000003084
GO:0000076 DNA replication checkpoint P
IGI
SpoSPAC821.08c
GO:0006414 translational elongation P
RCA
SceS000003084
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00001511
GO:0006911 phagocytosis, engulfment P
IMP
DmeFBgn0001086
GO:0007049 cell cycle P
IMP
DmeFBgn0001086
GO:0007067 mitosis P
IMP
CelWBGene00001510
GO:0007091 mitotic metaphase/anaphase transition P
IMP
CelWBGene00001511
TAS
SceS000002971
S000003084
GO:0007092 activation of mitotic anaphase-promoting complex
activity		 P
IMP
SceS000002971
S000003084
TAS
SpoSPAC144.13c
SPAC821.08c
GO:0007094 mitotic cell cycle spindle assembly
checkpoint		 P
IGI
SpoSPAC821.08c
GO:0007096 regulation of exit from mitosis P
TAS
DmeFBgn0001086
GO:0007126 meiosis P
IEP
SpoSPBC1198.12
IMP
CelWBGene00001510
GO:0007127 meiosis I P
IEP
SceS000003457
IMP
SceS000003457
GO:0007138 meiotic anaphase II P
IMP
SpoSPBC1198.12
GO:0007143 female meiosis P
IMP
DmeFBgn0000351
GO:0007144 female meiosis I P
IGI
DmeFBgn0000351
FBgn0001086
GO:0007147 female meiosis II P
IMP
DmeFBgn0000351
FBgn0001086
GO:0007165 signal transduction P
ISS
AthAt4g33270
At4g33260
At5g13840
At5g27570
At4g22910
At5g27080
At5g26900
At4g11920
GO:0007279 pole cell formation P
IMP
DmeFBgn0000351
GO:0007343 egg activation P
IMP
DmeFBgn0000351
GO:0007349 cellularization P
IMP
DmeFBgn0000351
GO:0008054 cyclin catabolic process P
IDA
DmeFBgn0001086
IMP
DmeFBgn0000351
FBgn0001086
SceS000002971
SpoSPAC144.13c
GO:0008150 biological_process P
ND
AthAt5g27940
SpoSPAC13G6.08
SPCC1620.04c
GO:0008340 determination of adult lifespan P
IMP
CelWBGene00001511
GO:0008361 regulation of cell size P
IMP
SceS000002971
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00001511
WBGene00001510
GO:0009987 cellular process P
IMP
DmeFBgn0001086
GO:0010091 trichome branching P
IMP
AthAt4g22910
GO:0010171 body morphogenesis P
IMP
CelWBGene00001511
GO:0010697 negative regulation of spindle pole body
separation		 P
IGI
SceS000002971
IMP
SceS000002971
GO:0016049 cell growth P
IMP
AthAt4g22910
GO:0016567 protein ubiquitination P
IPI
SceS000002971
GO:0018991 oviposition P
IMP
CelWBGene00001510
GO:0030162 regulation of proteolysis P
TAS
DmeFBgn0001086
GO:0030163 protein catabolic process P
IMP
DmeFBgn0001086
SceS000003084
S000003457
IPI
SceS000003457
GO:0030435 sporulation resulting in formation of a cellular
spore		 P
RCA
SceS000003457
GO:0030437 ascospore formation P
IMP
SceS000003457
SpoSPBC1198.12
GO:0030476 ascospore wall assembly P
IMP
SceS000003457
GO:0030718 germ-line stem cell maintenance P
IMP
DmeFBgn0001086
GO:0030996 cell cycle arrest in response to nitrogen
starvation		 P
IMP
SpoSPAC144.13c
GO:0031137 regulation of conjugation with cellular
fusion		 P
IMP
SpoSPAC144.13c
GO:0031577 spindle checkpoint P
IPI
SpoSPAC821.08c
GO:0032877 positive regulation of DNA endoreduplication P
IMP
AthAt4g11920
GO:0034613 cellular protein localization P
IGI
SpoSPAC821.08c
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00001511
GO:0042023 DNA endoreduplication P
IMP
AthAt4g22910
GO:0045143 homologous chromosome segregation P
TAS
DmeFBgn0000351
GO:0045736 negative regulation of cyclin-dependent protein
kinase activity		 P
IC
SpoSPAC144.13c
GO:0045842 positive regulation of mitotic metaphase/anaphase
transition		 P
IPI
SpoSPAC821.08c
GO:0050790 regulation of catalytic activity P
RCA
SceS000002971
GO:0051487 activation of anaphase-promoting complex activity
involved in meiotic cell cycle		 P
IGI
SpoSPBC1198.12
IMP
DmeFBgn0000351
GO:0051726 regulation of cell cycle P
RCA
SceS000002971

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
9444

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) FZR1 GI:33620742
Canis familiaris (Cfa) FZR1 GI:73987195
Mus musculus (Mmu) Fzr1
(MGI:1926790)		 GI:9789959 C0LZ42
Rattus norvegicus (Rno) Fzr1 GI:109480194
Gallus gallus (Gga) FZR1 GI:45383810
Drosophila melanogaster (Dme) rap
(FBgn0003200)		 GI:24639729
Anopheles gambiae (Aga) AgaP_AGAP002114 GI:158301189
Caenorhabditis elegans (Cel) fzr-1
(CE01695;
WBGene00001510)		 GI:17538129 Q09649
Schizosaccharomyces pombe (Spo) srw1
(SPAC144.13c)		 GI:19115586 O13286
Saccharomyces cerevisiae (Sce) CDH1
(S000002971)		 GI:6321435 P53197
Kluyveromyces lactis (Kla) KLLA0A08822g GI:50302899
Eremothecium gossypii (Ego) AGOS_AFL007C GI:45198512
Neurospora crassa (Ncr) NCU01269.1 GI:32412564
Arabidopsis thaliana (Ath) FZR2 GI:79482624
Arabidopsis thaliana (Ath) CCS52A2 GI:30681950
Oryza sativa (Osa) Os03g0123300 GI:115450407