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Search term: YGL006W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name PMC1
SGD link S000002974
Alternative ID YGL006W
Description Vacuolar Ca2+ ATPase involved in depleting cytosol of Ca2+ ions; prevents growth inhibition by activation of calcineurin in the presence of elevated concentrations of calcium; similar to mammalian PMCA1a
Synonyms YGL006W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0204 ACDHYP-

KOGs classification KOGs description
METABOLISM Calcium transporting ATPase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g27770 GI:12320888
Arabidopsis thaliana (Ath) At2g22950 GI:15227768
Arabidopsis thaliana (Ath) At2g41560 GI:15227380
Arabidopsis thaliana (Ath) At3g21180 GI:15232487
Arabidopsis thaliana (Ath) At3g22910 GI:15228891
Arabidopsis thaliana (Ath) At3g57330 GI:15230278
Arabidopsis thaliana (Ath) At3g63380 GI:15229421
Arabidopsis thaliana (Ath) At4g29900 GI:15233753
Arabidopsis thaliana (Ath) At4g37640 GI:15235643
Arabidopsis thaliana (Ath) At5g53010 GI:15237332
Arabidopsis thaliana (Ath) At5g57110 GI:15242036
Caenorhabditis elegans (Cel) CE25154 GI:17541616
Caenorhabditis elegans (Cel) CE28372
(WBGene00003153)		 GI:17543974
Caenorhabditis elegans (Cel) CE28373 GI:17543976
Caenorhabditis elegans (Cel) CE28747
(WBGene00019875)		 GI:17541776 Q9TYP9
Drosophila melanogaster (Dme) 7304318 GI:7304318
Homo sapiens (Hsa) Hs4502289 GI:4502289
Homo sapiens (Hsa) Hs22046739 GI:22046739
Homo sapiens (Hsa) Hs11386155 GI:11386155
Homo sapiens (Hsa) Hs4502287 GI:4502287
Homo sapiens (Hsa) Hs4757808 GI:4757808
Saccharomyces cerevisiae (Sce) YGL006w
(S000002974)		 GI:6321432 P38929
Schizosaccharomyces pombe (Spo) SPAPB2B4.04c GI:19114802 Q9HDW7
Arabidopsis thaliana (Ath) At1g27770 GI:12320888
Arabidopsis thaliana (Ath) At2g22950 GI:15227768
Arabidopsis thaliana (Ath) At2g41560 GI:15227380
Arabidopsis thaliana (Ath) At3g21180 GI:15232487
Arabidopsis thaliana (Ath) At3g22910 GI:15228891
Arabidopsis thaliana (Ath) At3g57330 GI:15230278
Arabidopsis thaliana (Ath) At3g63380 GI:15229421
Arabidopsis thaliana (Ath) At4g29900 GI:15233753
Arabidopsis thaliana (Ath) At4g37640 GI:15235643
Arabidopsis thaliana (Ath) At5g53010 GI:15237332
Arabidopsis thaliana (Ath) At5g57110 GI:15242036
Caenorhabditis elegans (Cel) CE25154 GI:17541616
Caenorhabditis elegans (Cel) CE28372
(WBGene00003153)		 GI:17543974
Caenorhabditis elegans (Cel) CE28373 GI:17543976
Caenorhabditis elegans (Cel) CE28747
(WBGene00019875)		 GI:17541776 Q9TYP9
Drosophila melanogaster (Dme) 7304318 GI:7304318
Homo sapiens (Hsa) Hs4502289 GI:4502289
Homo sapiens (Hsa) Hs22046739 GI:22046739
Homo sapiens (Hsa) Hs11386155 GI:11386155
Homo sapiens (Hsa) Hs4502287 GI:4502287
Homo sapiens (Hsa) Hs4757808 GI:4757808
Saccharomyces cerevisiae (Sce) YGL006w
(S000002974)		 GI:6321432 P38929
Schizosaccharomyces pombe (Spo) SPAPB2B4.04c GI:19114802 Q9HDW7
Arabidopsis thaliana (Ath) At1g27770 GI:12320888
Arabidopsis thaliana (Ath) At2g22950 GI:15227768
Arabidopsis thaliana (Ath) At2g41560 GI:15227380
Arabidopsis thaliana (Ath) At3g21180 GI:15232487
Arabidopsis thaliana (Ath) At3g22910 GI:15228891
Arabidopsis thaliana (Ath) At3g57330 GI:15230278
Arabidopsis thaliana (Ath) At3g63380 GI:15229421
Arabidopsis thaliana (Ath) At4g29900 GI:15233753
Arabidopsis thaliana (Ath) At4g37640 GI:15235643
Arabidopsis thaliana (Ath) At5g53010 GI:15237332
Arabidopsis thaliana (Ath) At5g57110 GI:15242036
Caenorhabditis elegans (Cel) CE25154 GI:17541616
Caenorhabditis elegans (Cel) CE28372
(WBGene00003153)		 GI:17543974
Caenorhabditis elegans (Cel) CE28373 GI:17543976
Caenorhabditis elegans (Cel) CE28747
(WBGene00019875)		 GI:17541776 Q9TYP9
Drosophila melanogaster (Dme) 7304318 GI:7304318
Homo sapiens (Hsa) Hs4502289 GI:4502289
Homo sapiens (Hsa) Hs22046739 GI:22046739
Homo sapiens (Hsa) Hs11386155 GI:11386155
Homo sapiens (Hsa) Hs4502287 GI:4502287
Homo sapiens (Hsa) Hs4757808 GI:4757808
Saccharomyces cerevisiae (Sce) YGL006w
(S000002974)		 GI:6321432 P38929
Schizosaccharomyces pombe (Spo) SPAPB2B4.04c GI:19114802 Q9HDW7


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000325 plant-type vacuole C
IDA
AthAt2g41560
GO:0000329 fungal-type vacuole membrane C
IDA
SceS000002974
SpoSPAPB2B4.04c
GO:0005773 vacuole C
IDA
AthAt3g57330
At2g41560
TAS
AthAt2g41560
GO:0005774 vacuolar membrane C
IDA
AthAt2g41560
GO:0005783 endoplasmic reticulum C
IDA
AthAt4g37640
At1g27770
GO:0005789 endoplasmic reticulum membrane C
IDA
AthAt4g37640
GO:0005886 plasma membrane C
IDA
AthAt2g41560
At3g57330
At4g29900
At3g21180
At4g37640
At1g27770
At5g57110
CelWBGene00003153
GO:0009507 chloroplast C
IDA
AthAt3g57330
At2g41560
GO:0009706 chloroplast inner membrane C
IDA
AthAt1g27770
TAS
AthAt1g27770
GO:0016020 membrane C
IDA
AthAt5g57110
GO:0005262 calcium channel activity F
TAS
AthAt1g27770
GO:0005388 calcium-transporting ATPase activity F
IDA
AthAt3g21180
At4g37640
At5g57110
IGI
SceS000002974
IMP
SceS000002974
ISS
AthAt3g57330
At4g37640
At3g22910
At2g41560
At2g22950
At1g27770
At3g63380
At4g29900
At3g21180
At5g53010
At5g57110
CelWBGene00003153
SpoSPAPB2B4.04c
TAS
AthAt1g27770
GO:0005509 calcium ion binding F
ISS
SpoSPAPB2B4.04c
GO:0005516 calmodulin binding F
IDA
AthAt2g41560
At4g37640
At3g21180
ISS
AthAt2g22950
At3g63380
At3g57330
At4g29900
At3g22910
At3g21180
At5g53010
TAS
AthAt4g37640
At2g41560
At1g27770
At5g57110
GO:0005524 ATP binding F
IC
SpoSPAPB2B4.04c
GO:0015085 calcium ion transmembrane transporter
activity		 F
IDA
AthAt4g37640
GO:0043621 protein self-association F
IDA
AthAt5g57110
GO:0000003 reproduction P
IMP
CelWBGene00019875
GO:0002119 nematode larval development P
IMP
CelWBGene00003153
GO:0006200 ATP catabolic process P
ISS
SpoSPAPB2B4.04c
GO:0006810 transport P
IDA
AthAt4g37640
GO:0006811 ion transport P
RCA
SceS000002974
GO:0006816 calcium ion transport P
IMP
CelWBGene00003153
SceS000002974
ISS
SpoSPAPB2B4.04c
GO:0006874 cellular calcium ion homeostasis P
IGI
SpoSPAPB2B4.04c
IMP
SceS000002974
SpoSPAPB2B4.04c
GO:0006897 endocytosis P
IMP
CelWBGene00003153
GO:0006914 autophagy P
RCA
SceS000002974
GO:0006970 response to osmotic stress P
IGI
AthAt2g41560
GO:0007039 vacuolar protein catabolic process P
RCA
SceS000002974
GO:0007338 single fertilization P
IMP
AthAt3g21180
GO:0008340 determination of adult lifespan P
IMP
CelWBGene00003153
GO:0009117 nucleotide metabolic process P
RCA
SceS000002974
GO:0009555 pollen development P
IMP
AthAt3g21180
GO:0009624 response to nematode P
IEP
AthAt2g41560
At5g57110
GO:0009651 response to salt stress P
IGI
AthAt2g41560
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00003153
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00003153
WBGene00019875
GO:0040011 locomotion P
IMP
CelWBGene00003153
WBGene00019875
GO:0040017 positive regulation of locomotion P
IMP
CelWBGene00003153
GO:0040018 positive regulation of multicellular organism
growth		 P
IMP
CelWBGene00019875
GO:0045807 positive regulation of endocytosis P
IMP
CelWBGene00003153
GO:0048281 inflorescence morphogenesis P
IGI
AthAt4g29900
GO:0048367 shoot development P
IGI
AthAt4g29900
GO:0050801 ion homeostasis P
RCA
SceS000002974
GO:0051481 reduction of cytosolic calcium ion
concentration		 P
IMP
CelWBGene00003153
GO:0055085 transmembrane transport P
IMP
SceS000002974
GO:0070588 calcium ion transmembrane transport P
IC
SpoSPAPB2B4.04c

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
56150

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) ATP2B2 GI:48255951
Pan troglodytes (Ptr) ATP2B2 GI:114585406
Canis familiaris (Cfa) ATP2B2 GI:73984670
Mus musculus (Mmu) Atp2b2
(MGI:105368)		 GI:6753140 Q3UHH0
Rattus norvegicus (Rno) Atp2b2
(RGD:2176)		 GI:6978557 91
Gallus gallus (Gga) ATP2B2 GI:118096785
Schizosaccharomyces pombe (Spo) SPAPB2B4.04c GI:19114802 Q9HDW7
Saccharomyces cerevisiae (Sce) PMC1
(S000002974)		 GI:6321432 P38929
Kluyveromyces lactis (Kla) KLLA0A08910g GI:50302907
Eremothecium gossypii (Ego) AGOS_AFL011W GI:45198508
Magnaporthe grisea (Mgr) MGG_02487 GI:145606180
Neurospora crassa (Ncr) NCU04736.1 GI:32406975
Arabidopsis thaliana (Ath) AT2G22950 GI:15227768
Arabidopsis thaliana (Ath) ACA2 GI:15235643
Oryza sativa (Osa) Os03g0203700 GI:115451413


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000329 fungal-type vacuole membrane C
IDA
SceS000002974
SpoSPAPB2B4.04c
GO:0005575 cellular_component C
ND
AthACA2
GO:0005737 cytoplasm C
IDA
HsaATP2B2
GO:0005783 endoplasmic reticulum C
IDA
AthACA2
MmuMGI:105368
GO:0005789 endoplasmic reticulum membrane C
IDA
AthACA2
GO:0005792 microsome C
IDA
MmuMGI:105368
GO:0005886 plasma membrane C
IDA
AthACA2
HsaATP2B2
MmuMGI:105368
NAS
HsaATP2B2
GO:0005929 cilium C
IDA
MmuMGI:105368
GO:0016324 apical plasma membrane C
IDA
MmuMGI:105368
ISO
MmuMGI:105368
GO:0030425 dendrite C
ISO
MmuMGI:105368
GO:0043025 neuronal cell body C
IDA
MmuMGI:105368
ISO
MmuMGI:105368
GO:0045121 membrane raft C
ISO
MmuMGI:105368
GO:0003674 molecular_function F
ND
AthACA2
GO:0004089 carbonate dehydratase activity F
ISS
AthACA2
GO:0005388 calcium-transporting ATPase activity F
IDA
AthACA2
HsaATP2B2
IGI
SceS000002974
IMP
SceS000002974
ISO
MmuMGI:105368
ISS
AthAt2g22950
ACA2
SpoSPAPB2B4.04c
NAS
HsaATP2B2
GO:0005509 calcium ion binding F
IDA
HsaATP2B2
ISS
SpoSPAPB2B4.04c
GO:0005515 protein binding F
IPI
HsaATP2B2
GO:0005516 calmodulin binding F
IDA
AthACA2
HsaATP2B2
ISS
AthAt2g22950
TAS
AthACA2
GO:0005524 ATP binding F
IC
SpoSPAPB2B4.04c
IDA
HsaATP2B2
ISO
MmuMGI:105368
GO:0008022 protein C-terminus binding F
IPI
HsaATP2B2
GO:0008270 zinc ion binding F
ISS
AthACA2
GO:0015085 calcium ion transmembrane transporter
activity		 F
IDA
AthACA2
GO:0030165 PDZ domain binding F
IDA
HsaATP2B2
ISO
MmuMGI:105368
GO:0030899 calcium-dependent ATPase activity F
IMP
MmuMGI:105368
GO:0035254 glutamate receptor binding F
ISO
MmuMGI:105368
GO:0000902 cell morphogenesis P
IMP
MmuMGI:105368
GO:0006200 ATP catabolic process P
IMP
MmuMGI:105368
ISS
SpoSPAPB2B4.04c
GO:0006730 one-carbon metabolic process P
ISS
AthACA2
GO:0006810 transport P
IDA
AthACA2
NAS
HsaATP2B2
GO:0006811 ion transport P
RCA
SceS000002974
GO:0006816 calcium ion transport P
IMP
MmuMGI:105368
SceS000002974
ISS
SpoSPAPB2B4.04c
GO:0006874 cellular calcium ion homeostasis P
IGI
SpoSPAPB2B4.04c
IMP
MmuMGI:105368
SceS000002974
SpoSPAPB2B4.04c
GO:0006914 autophagy P
RCA
SceS000002974
GO:0006996 organelle organization P
IMP
MmuMGI:105368
GO:0007039 vacuolar protein catabolic process P
RCA
SceS000002974
GO:0007595 lactation P
IMP
MmuMGI:105368
GO:0007605 sensory perception of sound P
IGI
MmuMGI:105368
IMP
HsaATP2B2
MmuMGI:105368
GO:0007626 locomotory behavior P
IMP
MmuMGI:105368
GO:0008150 biological_process P
ND
AthACA2
GO:0008361 regulation of cell size P
IMP
MmuMGI:105368
GO:0009117 nucleotide metabolic process P
RCA
SceS000002974
GO:0010037 response to carbon dioxide P
IEP
AthACA2
GO:0021549 cerebellum development P
IMP
MmuMGI:105368
GO:0021692 cerebellar Purkinje cell layer
morphogenesis		 P
IMP
MmuMGI:105368
GO:0021702 cerebellar Purkinje cell differentiation P
IMP
MmuMGI:105368
GO:0021707 cerebellar granule cell differentiation P
IMP
MmuMGI:105368
GO:0030182 neuron differentiation P
IDA
HsaATP2B2
GO:0040011 locomotion P
IMP
MmuMGI:105368
GO:0042428 serotonin metabolic process P
IMP
MmuMGI:105368
GO:0042472 inner ear morphogenesis P
IMP
MmuMGI:105368
GO:0045299 otolith mineralization P
IMP
MmuMGI:105368
GO:0046068 cGMP metabolic process P
IMP
MmuMGI:105368
GO:0048167 regulation of synaptic plasticity P
IMP
MmuMGI:105368
GO:0048839 inner ear development P
IMP
MmuMGI:105368
GO:0050801 ion homeostasis P
RCA
SceS000002974
GO:0050808 synapse organization P
IMP
MmuMGI:105368
GO:0050885 neuromuscular process controlling
balance		 P
IMP
MmuMGI:105368
GO:0050910 detection of mechanical stimulus involved in
sensory perception of sound		 P
IMP
MmuMGI:105368
GO:0051928 positive regulation of calcium ion
transport		 P
IMP
MmuMGI:105368
GO:0055085 transmembrane transport P
IMP
SceS000002974
GO:0060088 auditory receptor cell stereocilium
organization		 P
IMP
MmuMGI:105368
GO:0060113 inner ear receptor cell differentiation P
IMP
MmuMGI:105368
GO:0070588 calcium ion transmembrane transport P
IC
SpoSPAPB2B4.04c

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