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Search term: YGL020C


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name GET1
SGD link S000002988
Alternative ID YGL020C
Description Subunit of the GET complex; involved in insertion of proteins into the ER membrane; required for the retrieval of HDEL proteins from the Golgi to the ER in an ERD2 dependent fashion and for normal mitochondrial morphology and inheritance
Synonyms YGL020C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG4253 -CDHYP-

KOGs classification KOGs description
POORLY CHARACTERIZED Tryptophan-rich basic nuclear protein

Species KOG link NCBI link UniProt link
Caenorhabditis elegans (Cel) CE25345 GI:17565882
Drosophila melanogaster (Dme) 7295050_1 GI:17864558
Homo sapiens (Hsa) Hs21536428 GI:13655017
Homo sapiens (Hsa) Hs22042251 GI:22042251
Homo sapiens (Hsa) HsM4759326 GI:4759326
Saccharomyces cerevisiae (Sce) YGL020c
(S000002988)
GI:6321418 P53192
Schizosaccharomyces pombe (Spo) SPBC543.10 GI:19113590 Q9HGM2


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
SceS000002988
GO:0005783 endoplasmic reticulum C
IDA
SceS000002988
SpoSPBC543.10
ISS
SpoSPBC543.10
GO:0016021 integral to membrane C
ISM
SceS000002988
GO:0043529 GET complex C
IPI
SceS000002988
ISS
SpoSPBC543.10
GO:0003674 molecular_function F
ND
SpoSPBC543.10
GO:0043495 protein anchor F
IGI
SceS000002988
GO:0006874 cellular calcium ion homeostasis P
IMP
SceS000002988
ISS
SpoSPBC543.10
GO:0006886 intracellular protein transport P
RCA
SceS000002988
GO:0006890 retrograde vesicle-mediated transport, Golgi to
ER
P
IDA
SceS000002988
IGI
SceS000002988
IMP
SceS000002988
ISS
SpoSPBC543.10
GO:0006986 response to unfolded protein P
IMP
SceS000002988
GO:0007005 mitochondrion organization P
IMP
SceS000002988
GO:0007029 endoplasmic reticulum organization P
RCA
SceS000002988
GO:0015031 protein transport P
RCA
SceS000002988
GO:0034613 cellular protein localization P
IGI
SceS000002988
GO:0034620 cellular response to unfolded protein P
ISS
SpoSPBC543.10
GO:0045048 protein insertion into ER membrane P
IGI
SceS000002988
ISS
SpoSPBC543.10
GO:0045184 establishment of protein localization P
RCA
SceS000002988

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
39061

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) GET1
(S000002988)
GI:6321418 P53192
Kluyveromyces lactis (Kla) KLLA0A04796g GI:50302549
Eremothecium gossypii (Ego) AGOS_AFR006C GI:45198524


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
SceS000002988
GO:0005783 endoplasmic reticulum C
IDA
SceS000002988
GO:0016021 integral to membrane C
ISM
SceS000002988
GO:0043529 GET complex C
IPI
SceS000002988
GO:0043495 protein anchor F
IGI
SceS000002988
GO:0006874 cellular calcium ion homeostasis P
IMP
SceS000002988
GO:0006886 intracellular protein transport P
RCA
SceS000002988
GO:0006890 retrograde vesicle-mediated transport, Golgi to
ER
P
IDA
SceS000002988
IGI
SceS000002988
IMP
SceS000002988
GO:0006986 response to unfolded protein P
IMP
SceS000002988
GO:0007005 mitochondrion organization P
IMP
SceS000002988
GO:0007029 endoplasmic reticulum organization P
RCA
SceS000002988
GO:0015031 protein transport P
RCA
SceS000002988
GO:0034613 cellular protein localization P
IGI
SceS000002988
GO:0045048 protein insertion into ER membrane P
IGI
SceS000002988
GO:0045184 establishment of protein localization P
RCA
SceS000002988

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_31560

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Ashbya gossypii (Ago) ago3198 AFR006C
Candida glabrata (Cgl) cgl8 CAGL0A00253g
Kluyveromyces lactis (Kla) kla207 KLLA0A04796g
Saccharomyces cerevisiae (Sce) sce2112 YGL020C
(S000002988)


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
SceS000002988
GO:0005783 endoplasmic reticulum C
IDA
SceS000002988
GO:0016021 integral to membrane C
ISM
SceS000002988
GO:0043529 GET complex C
IPI
SceS000002988
GO:0043495 protein anchor F
IGI
SceS000002988
GO:0006874 cellular calcium ion homeostasis P
IMP
SceS000002988
GO:0006886 intracellular protein transport P
RCA
SceS000002988
GO:0006890 retrograde vesicle-mediated transport, Golgi to
ER
P
IDA
SceS000002988
IGI
SceS000002988
IMP
SceS000002988
GO:0006986 response to unfolded protein P
IMP
SceS000002988
GO:0007005 mitochondrion organization P
IMP
SceS000002988
GO:0007029 endoplasmic reticulum organization P
RCA
SceS000002988
GO:0015031 protein transport P
RCA
SceS000002988
GO:0034613 cellular protein localization P
IGI
SceS000002988
GO:0045048 protein insertion into ER membrane P
IGI
SceS000002988
GO:0045184 establishment of protein localization P
RCA
SceS000002988

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPBC543.10
(Q9HGM2)
YGL020C
(S000002988)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
SceS000002988
GO:0005783 endoplasmic reticulum C
IDA
SceS000002988
SpoSPBC543.10
ISS
SpoSPBC543.10
GO:0016021 integral to membrane C
ISM
SceS000002988
GO:0043529 GET complex C
IPI
SceS000002988
ISS
SpoSPBC543.10
GO:0003674 molecular_function F
ND
SpoSPBC543.10
GO:0043495 protein anchor F
IGI
SceS000002988
GO:0006874 cellular calcium ion homeostasis P
IMP
SceS000002988
ISS
SpoSPBC543.10
GO:0006886 intracellular protein transport P
RCA
SceS000002988
GO:0006890 retrograde vesicle-mediated transport, Golgi to
ER
P
IDA
SceS000002988
IGI
SceS000002988
IMP
SceS000002988
ISS
SpoSPBC543.10
GO:0006986 response to unfolded protein P
IMP
SceS000002988
GO:0007005 mitochondrion organization P
IMP
SceS000002988
GO:0007029 endoplasmic reticulum organization P
RCA
SceS000002988
GO:0015031 protein transport P
RCA
SceS000002988
GO:0034613 cellular protein localization P
IGI
SceS000002988
GO:0034620 cellular response to unfolded protein P
ISS
SpoSPBC543.10
GO:0045048 protein insertion into ER membrane P
IGI
SceS000002988
ISS
SpoSPBC543.10
GO:0045184 establishment of protein localization P
RCA
SceS000002988

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s.khadayate@ucl.ac.uk