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Search term: YGL033W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name HOP2
SGD link S000003001
Alternative ID YGL033W
Description Meiosis-specific protein that localizes to chromosomes, preventing synapsis between nonhomologous chromosomes and ensuring synapsis between homologs; complexes with Mnd1p to promote homolog pairing and meiotic double-strand break repair
Synonyms YGL033W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
39054

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) HOP2
(S000003001)		 GI:9755333
Kluyveromyces lactis (Kla) KLLA0E10923g GI:50308877
Eremothecium gossypii (Ego) AGOS_AFR474W GI:45198992


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000794 condensed nuclear chromosome C
IDA
SceS000003001
GO:0003690 double-stranded DNA binding F
IDA
SceS000003001
IPI
SceS000003001
GO:0005515 protein binding F
IPI
SceS000003001
GO:0007129 synapsis P
IMP
SceS000003001
GO:0007131 reciprocal meiotic recombination P
IMP
SceS000003001

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_4322

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago3666 AFR474W
Arabidopsis thaliana (Ath) ath1402 At1g13330.1
Candida glabrata (Cgl) cgl62 CAGL0A01606g
Cryptococcus neoformans (Cne) cne3570 176.m02577
Dictyostelium discoideum (Ddi) ddi6630 DDB0203941
Debaryomyces hansenii (Dha) dha2898 DEHA0D13442g
Danio rerio (Dre) dre22688 ENSDARP00000022914
Encephalitozoon cuniculi (Ecu) ecu1744 19075107
Takifugu rubripes (Fru) fru20930 SINFRUP00000138203
Homo sapiens (Hsa) hsa13718 ENSP00000253789
(PSMC3IP)		 Q9P2W1-2
Homo sapiens (Hsa) hsa13719 ENSP00000341011
Kluyveromyces lactis (Kla) kla3442 KLLA0E10923g
Mus musculus (Mmu) mmu4843 ENSMUSP00000019447
(MGI:1098610)		 O35047
Oryza sativa (Osa) osa728 902.m00119
Rattus norvegicus (Rno) rno6155 ENSRNOP00000027159
(RGD:621885)		 Q91ZY6
Saccharomyces cerevisiae (Sce) sce2125 YGL033W
(S000003001)
Schizosaccharomyces pombe (Spo) spo4869 SPAC222.15 Q9HGK2


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000790 nuclear chromatin C
NAS
SpoSPAC222.15
GO:0000794 condensed nuclear chromosome C
IDA
SceS000003001
GO:0005575 cellular_component C
ND
AthAt1g13330
GO:0005634 nucleus C
IDA
SpoSPAC222.15
GO:0005816 spindle pole body C
IDA
SpoSPAC222.15
GO:0005819 spindle C
IDA
SpoSPAC222.15
GO:0005829 cytosol C
IDA
SpoSPAC222.15
GO:0003674 molecular_function F
ND
AthAt1g13330
GO:0003690 double-stranded DNA binding F
IDA
SceS000003001
IPI
SceS000003001
GO:0005515 protein binding F
IPI
SceS000003001
SpoSPAC222.15
GO:0030331 estrogen receptor binding F
ISO
MmuMGI:1098610
GO:0035259 glucocorticoid receptor binding F
ISO
MmuMGI:1098610
GO:0046966 thyroid hormone receptor binding F
ISO
MmuMGI:1098610
GO:0050681 androgen receptor binding F
ISO
MmuMGI:1098610
GO:0007129 synapsis P
IMP
SceS000003001
SpoSPAC222.15
GO:0007131 reciprocal meiotic recombination P
IMP
SceS000003001
SpoSPAC222.15
GO:0045944 positive regulation of transcription from RNA
polymerase II promoter		 P
ISO
MmuMGI:1098610
GO:0051026 chiasma assembly P
IMP
AthAt1g13330

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC222.15
(Q9HGK2)		 YGL033W
(S000003001)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000790 nuclear chromatin C
NAS
SpoSPAC222.15
GO:0000794 condensed nuclear chromosome C
IDA
SceS000003001
GO:0005634 nucleus C
IDA
SpoSPAC222.15
GO:0005816 spindle pole body C
IDA
SpoSPAC222.15
GO:0005819 spindle C
IDA
SpoSPAC222.15
GO:0005829 cytosol C
IDA
SpoSPAC222.15
GO:0003690 double-stranded DNA binding F
IDA
SceS000003001
IPI
SceS000003001
GO:0005515 protein binding F
IPI
SceS000003001
SpoSPAC222.15
GO:0007129 synapsis P
IMP
SceS000003001
SpoSPAC222.15
GO:0007131 reciprocal meiotic recombination P
IMP
SceS000003001
SpoSPAC222.15

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s.khadayate@ucl.ac.uk