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Search term: YGL058W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name RAD6
SGD link S000003026
Alternative ID YGL058W
Description Ubiquitin-conjugating enzyme (E2), involved in postreplication repair (as a heterodimer with Rad18p), DSBR and checkpoint control (as a heterodimer with Bre1p), ubiquitin-mediated N-end rule protein degradation (as a heterodimer with Ubr1p
Synonyms YGL058W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0419 ACDHYPE

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Ubiquitin-protein ligase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g14400 GI:18394114
Arabidopsis thaliana (Ath) At2g02760 GI:18395424
Arabidopsis thaliana (Ath) At5g62540 GI:18424601
Caenorhabditis elegans (Cel) CE27822
(WBGene00006701)		 GI:17542650 P52478
Drosophila melanogaster (Dme) 7296802 GI:14286180
Homo sapiens (Hsa) Hs4507771
(UBE2B)		 GI:4507771 P63146
Homo sapiens (Hsa) Hs18546173 GI:18546173
Homo sapiens (Hsa) Hs4507769 GI:4507769
Saccharomyces cerevisiae (Sce) YGL058w
(S000003026)		 GI:6321380 P06104
Schizosaccharomyces pombe (Spo) SPAC18B11.07c GI:19113788 P23566
Encephalitozoon cuniculi (Ecu) ECU10g1310i GI:19074740 Q8SR17
Arabidopsis thaliana (Ath) At1g14400 GI:18394114
Arabidopsis thaliana (Ath) At2g02760 GI:18395424
Arabidopsis thaliana (Ath) At5g62540 GI:18424601
Caenorhabditis elegans (Cel) CE27822
(WBGene00006701)		 GI:17542650 P52478
Drosophila melanogaster (Dme) 7296802 GI:14286180
Homo sapiens (Hsa) Hs4507771
(UBE2B)		 GI:4507771 P63146
Homo sapiens (Hsa) Hs18546173 GI:18546173
Homo sapiens (Hsa) Hs4507769 GI:4507769
Saccharomyces cerevisiae (Sce) YGL058w
(S000003026)		 GI:6321380 P06104
Schizosaccharomyces pombe (Spo) SPAC18B11.07c GI:19113788 P23566
Encephalitozoon cuniculi (Ecu) ECU10g1310i GI:19074740 Q8SR17
Arabidopsis thaliana (Ath) At1g14400 GI:18394114
Arabidopsis thaliana (Ath) At2g02760 GI:18395424
Arabidopsis thaliana (Ath) At5g62540 GI:18424601
Caenorhabditis elegans (Cel) CE27822
(WBGene00006701)		 GI:17542650 P52478
Drosophila melanogaster (Dme) 7296802 GI:14286180
Homo sapiens (Hsa) Hs4507771
(UBE2B)		 GI:4507771 P63146
Homo sapiens (Hsa) Hs18546173 GI:18546173
Homo sapiens (Hsa) Hs4507769 GI:4507769
Saccharomyces cerevisiae (Sce) YGL058w
(S000003026)		 GI:6321380 P06104
Schizosaccharomyces pombe (Spo) SPAC18B11.07c GI:19113788 P23566
Encephalitozoon cuniculi (Ecu) ECU10g1310i GI:19074740 Q8SR17


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0071894
IDA
SpoSPAC18B11.07c
IMP
SpoSPAC18B11.07c
GO:0000502 proteasome complex C
IPI
SceS000003026
GO:0000785 chromatin C
ISS
HsaUBE2B
GO:0000790 nuclear chromatin C
IDA
SceS000003026
NAS
SpoSPAC18B11.07c
GO:0005575 cellular_component C
ND
AthAt5g62540
GO:0005634 nucleus C
IDA
HsaUBE2B
SceS000003026
SpoSPAC18B11.07c
NAS
SpoSPAC18B11.07c
GO:0005657 replication fork C
IDA
HsaUBE2B
GO:0005737 cytoplasm C
IDA
HsaUBE2B
SceS000003026
GO:0005829 cytosol C
IDA
SpoSPAC18B11.07c
GO:0033503 HULC complex C
IDA
SpoSPAC18B11.07c
GO:0003684 damaged DNA binding F
ISS
CelWBGene00006701
GO:0004842 ubiquitin-protein ligase activity F
IDA
AthAt5g62540
At1g14400
At2g02760
CelWBGene00006701
HsaUBE2B
SceS000003026
SpoSPAC18B11.07c
IMP
HsaUBE2B
ISS
AthAt2g02760
At1g14400
At5g62540
CelWBGene00006701
GO:0005515 protein binding F
IPI
HsaUBE2B
GO:0031625 ubiquitin protein ligase binding F
IPI
HsaUBE2B
GO:0000003 reproduction P
IMP
CelWBGene00006701
GO:0000209 protein polyubiquitination P
IMP
HsaUBE2B
SceS000003026
GO:0000724 double-strand break repair via homologous
recombination		 P
IGI
SceS000003026
GO:0002119 nematode larval development P
IMP
CelWBGene00006701
GO:0006281 DNA repair P
IDA
CelWBGene00006701
IGI
HsaUBE2B
GO:0006301 postreplication repair P
IDA
HsaUBE2B
IGI
SpoSPAC18B11.07c
NAS
HsaUBE2B
GO:0006336 DNA replication-independent nucleosome
assembly		 P
TAS
SpoSPAC18B11.07c
GO:0006338 chromatin remodeling P
IMP
SpoSPAC18B11.07c
GO:0006342 chromatin silencing P
IMP
SpoSPAC18B11.07c
GO:0006348 chromatin silencing at telomere P
IMP
SceS000003026
GO:0006366 transcription from RNA polymerase II
promoter		 P
IPI
SceS000003026
GO:0006368 RNA elongation from RNA polymerase II
promoter		 P
IEP
SpoSPAC18B11.07c
GO:0006511 ubiquitin-dependent protein catabolic
process		 P
IDA
AthAt2g02760
At5g62540
At1g14400
HsaUBE2B
NAS
HsaUBE2B
TAS
AthAt1g14400
At2g02760
At5g62540
GO:0006513 protein monoubiquitination P
IMP
HsaUBE2B
SceS000003026
GO:0006974 response to DNA damage stimulus P
IDA
HsaUBE2B
GO:0007283 spermatogenesis P
TAS
HsaUBE2B
GO:0009411 response to UV P
IGI
HsaUBE2B
GO:0009650 UV protection P
IGI
AthAt2g02760
GO:0009910 negative regulation of flower development P
IGI
AthAt1g14400
GO:0009965 leaf morphogenesis P
IGI
AthAt1g14400
GO:0010228 vegetative to reproductive phase transition of
meristem		 P
IGI
AthAt2g02760
At1g14400
GO:0010390 histone monoubiquitination P
IMP
SceS000003026
GO:0016567 protein ubiquitination P
IDA
CelWBGene00006701
HsaUBE2B
GO:0030466 chromatin silencing at silent mating-type
cassette		 P
IGI
SpoSPAC18B11.07c
GO:0031144 proteasome localization P
IMP
SpoSPAC18B11.07c
GO:0031497 chromatin assembly P
IMP
SpoSPAC18B11.07c
GO:0031571 G1/S DNA damage checkpoint P
IMP
SceS000003026
GO:0033522 histone H2A ubiquitination P
IMP
HsaUBE2B
GO:0033523 histone H2B ubiquitination P
IGI
AthAt1g14400
At2g02760
GO:0040007 growth P
IMP
CelWBGene00006701
GO:0042138 meiotic DNA double-strand break
formation		 P
IMP
SceS000003026
GO:0042275 error-free postreplication DNA
repair		 P
IGI
SceS000003026
GO:0042276 error-prone translesion synthesis P
IGI
SceS000003026
GO:0042493 response to drug P
IDA
HsaUBE2B
GO:0042787 protein ubiquitination involved in
ubiquitin-dependent protein catabolic
process		 P
IMP
SceS000003026
GO:0043161 proteasomal ubiquitin-dependent protein catabolic
process		 P
IDA
HsaUBE2B
IMP
SpoSPAC18B11.07c
GO:0043951 negative regulation of cAMP-mediated
signaling		 P
IDA
HsaUBE2B
GO:0045941 positive regulation of transcription P
RCA
SceS000003026
GO:0050821 protein stabilization P
IMP
HsaUBE2B
GO:0051568 histone H3-K4 methylation P
IMP
SpoSPAC18B11.07c
GO:0051865 protein autoubiquitination P
IDA
HsaUBE2B
GO:0060070 canonical Wnt receptor signaling
pathway		 P
ISS
HsaUBE2B
GO:0070534 protein K63-linked ubiquitination P
IDA
HsaUBE2B
GO:0070936 protein K48-linked ubiquitination P
IDA
HsaUBE2B
GO:0070979 protein K11-linked ubiquitination P
IDA
HsaUBE2B
GO:0070987 error-free translesion synthesis P
IGI
SceS000003026
GO:0071596 ubiquitin-dependent protein catabolic process via
the N-end rule pathway		 P
IMP
SceS000003026
GO:0090089 regulation of dipeptide transport P
IMP
SceS000003026

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
101298

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) UBE2B GI:4507771 P63146
Pan troglodytes (Ptr) UBE2B GI:114601701
Canis familiaris (Cfa) UBE2B GI:73970740
Mus musculus (Mmu) Ube2b
(MGI:102944)		 GI:31560630 A2RSE4
Rattus norvegicus (Rno) Ube2b
(RGD:708345)		 GI:13592123
Schizosaccharomyces pombe (Spo) rhp6
(SPAC18B11.07c)		 GI:19113788 P23566
Saccharomyces cerevisiae (Sce) RAD6
(S000003026)		 GI:6321380 P06104
Kluyveromyces lactis (Kla) KLLA0C05632g GI:50304985
Eremothecium gossypii (Ego) AGOS_AAR156C GI:45184981
Magnaporthe grisea (Mgr) MGG_01756 GI:145613279
Neurospora crassa (Ncr) NCU09731.1 GI:32419875