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Search term: YGL086W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name MAD1
SGD link S000003054
Alternative ID YGL086W
Description Coiled-coil protein involved in the spindle-assembly checkpoint; phosphorylated by Mps1p upon checkpoint activation which leads to inhibition of the activity of the anaphase promoting complex; forms a complex with Mad2p
Synonyms YGL086W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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Search for GO info:  

GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG4593 A-DHYPE

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Mitotic checkpoint protein MAD1

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At5g49880 GI:15240571
Drosophila melanogaster (Dme) 7303911 GI:4530484
Homo sapiens (Hsa) Hs22062407 GI:4416457 Q9Y6D9
Homo sapiens (Hsa) Hs4505065 GI:4505065
Saccharomyces cerevisiae (Sce) YGL086w
(S000003054)		 GI:6321352 P40957
Schizosaccharomyces pombe (Spo) SPBC3D6.04c GI:19112308 P87169
Encephalitozoon cuniculi (Ecu) ECU02g0920 GI:19074011 Q8SWC6


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000776 kinetochore C
IDA
SceS000003054
IMP
SceS000003054
GO:0000778 condensed nuclear chromosome kinetochore C
IDA
SpoSPBC3D6.04c
GO:0005634 nucleus C
IDA
SceS000003054
SpoSPBC3D6.04c
GO:0005643 nuclear pore C
IDA
SceS000003054
GO:0003674 molecular_function F
ND
SceS000003054
GO:0005515 protein binding F
IPI
SpoSPBC3D6.04c
GO:0000278 mitotic cell cycle P
RCA
SceS000003054
GO:0000279 M phase P
RCA
SceS000003054
GO:0006461 protein complex assembly P
RCA
SceS000003054
GO:0006913 nucleocytoplasmic transport P
IGI
SceS000003054
IPI
SceS000003054
GO:0007093 mitotic cell cycle checkpoint P
ISS
AthAt5g49880
GO:0007094 mitotic cell cycle spindle assembly
checkpoint		 P
IGI
SceS000003054
IMP
SceS000003054
TAS
SpoSPBC3D6.04c
GO:0070683 decatenation checkpoint P
IGI
SceS000003054

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
74500

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) MAD1L1 GI:62243369
Pan troglodytes (Ptr) MAD1L1 GI:114611968
Canis familiaris (Cfa) MAD1L1 GI:73958203
Mus musculus (Mmu) Mad1l1
(MGI:1341857)		 GI:88014564 Q3TDV6
Rattus norvegicus (Rno) Mad1l1 GI:109495304
Gallus gallus (Gga) MAD1L1 GI:118097776
Drosophila melanogaster (Dme) TXBP181-like
(FBgn0026326)		 GI:24652071
Anopheles gambiae (Aga) AgaP_AGAP006632 GI:158296195
Schizosaccharomyces pombe (Spo) mad1
(SPBC3D6.04c)		 GI:19112308 P87169
Saccharomyces cerevisiae (Sce) MAD1
(S000003054)		 GI:6321352 P40957
Kluyveromyces lactis (Kla) KLLA0E19239g GI:50309611
Eremothecium gossypii (Ego) AGOS_AFL065C GI:45198454
Magnaporthe grisea (Mgr) MGG_04908 GI:39940664
Neurospora crassa (Ncr) NCU04428.1 GI:32406336
Arabidopsis thaliana (Ath) AT5G49880 GI:15240571
Oryza sativa (Osa) Os01g0877300 GI:115441387


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000776 kinetochore C
IDA
HsaMAD1L1
SceS000003054
IMP
SceS000003054
GO:0000778 condensed nuclear chromosome kinetochore C
IDA
SpoSPBC3D6.04c
GO:0005634 nucleus C
IDA
SceS000003054
SpoSPBC3D6.04c
GO:0005643 nuclear pore C
IDA
HsaMAD1L1
SceS000003054
GO:0005813 centrosome C
NAS
HsaMAD1L1
GO:0005819 spindle C
NAS
HsaMAD1L1
GO:0005829 cytosol C
EXP
HsaMAD1L1
GO:0003674 molecular_function F
ND
SceS000003054
GO:0005515 protein binding F
IPI
HsaMAD1L1
SpoSPBC3D6.04c
GO:0000089 mitotic metaphase P
NAS
HsaMAD1L1
GO:0000090 mitotic anaphase P
NAS
HsaMAD1L1
GO:0000093 mitotic telophase P
NAS
HsaMAD1L1
GO:0000278 mitotic cell cycle P
RCA
SceS000003054
GO:0000279 M phase P
RCA
SceS000003054
GO:0006461 protein complex assembly P
RCA
SceS000003054
GO:0006913 nucleocytoplasmic transport P
IGI
SceS000003054
IPI
SceS000003054
GO:0007093 mitotic cell cycle checkpoint P
ISS
AthAt5g49880
NAS
HsaMAD1L1
GO:0007094 mitotic cell cycle spindle assembly
checkpoint		 P
IGI
SceS000003054
IMP
SceS000003054
TAS
SpoSPBC3D6.04c
GO:0070683 decatenation checkpoint P
IGI
SceS000003054

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_4393

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga2079 ENSANGP00000011542
Ashbya gossypii (Ago) ago3128 AFL065C
Candida glabrata (Cgl) cgl2198 CAGL0H03179g
Cryptococcus neoformans (Cne) cne3994 185.m02596
Dictyostelium discoideum (Ddi) ddi8735 DDB0187615
Debaryomyces hansenii (Dha) dha2557 DEHA0D05907g
Drosophila melanogaster (Dme) dme4062 CG2072-PA
(FBgn0026326)
Danio rerio (Dre) dre183 ENSDARP00000023567
Danio rerio (Dre) dre188 ENSDARP00000048609
(mad1l1)		 Q7ZW71
Takifugu rubripes (Fru) fru5961 SINFRUP00000155224
Gallus gallus (Gga) gga6401 ENSGALP00000006711
(MAD1L1)
Gallus gallus (Gga) gga6402 ENSGALP00000006713
Homo sapiens (Hsa) hsa28146 ENSP00000265854
(MAD1L1)		 A4D218
Kluyveromyces lactis (Kla) kla3816 KLLA0E19239g
Mus musculus (Mmu) mmu21205 ENSMUSP00000031534
(MGI:1341857)		 Q9WTX8-1
Mus musculus (Mmu) mmu21206 ENSMUSP00000074376
Neurospora crassa (Ncr) ncr4300 NCU04428.2
Rattus norvegicus (Rno) rno8146 ENSRNOP00000001709
(RGD:1596881)
Saccharomyces cerevisiae (Sce) sce2180 YGL086W
(S000003054)
Schizosaccharomyces pombe (Spo) spo4751 SPBC3D6.04c P87169
Yarrowia lipolytica (Yli) yli5087 YALI0E29623g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000776 kinetochore C
IDA
SceS000003054
IMP
SceS000003054
GO:0000778 condensed nuclear chromosome kinetochore C
IDA
SpoSPBC3D6.04c
GO:0005634 nucleus C
IDA
SceS000003054
SpoSPBC3D6.04c
GO:0005643 nuclear pore C
IDA
SceS000003054
GO:0003674 molecular_function F
ND
SceS000003054
GO:0005515 protein binding F
IPI
SpoSPBC3D6.04c
GO:0000278 mitotic cell cycle P
RCA
SceS000003054
GO:0000279 M phase P
RCA
SceS000003054
GO:0006461 protein complex assembly P
RCA
SceS000003054
GO:0006913 nucleocytoplasmic transport P
IGI
SceS000003054
IPI
SceS000003054
GO:0007094 mitotic cell cycle spindle assembly
checkpoint		 P
IGI
SceS000003054
IMP
SceS000003054
TAS
SpoSPBC3D6.04c
GO:0070683 decatenation checkpoint P
IGI
SceS000003054

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC3D6.04c
(P87169)		 YGL086W
(S000003054)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000776 kinetochore C
IDA
SceS000003054
IMP
SceS000003054
GO:0000778 condensed nuclear chromosome kinetochore C
IDA
SpoSPBC3D6.04c
GO:0005634 nucleus C
IDA
SceS000003054
SpoSPBC3D6.04c
GO:0005643 nuclear pore C
IDA
SceS000003054
GO:0003674 molecular_function F
ND
SceS000003054
GO:0005515 protein binding F
IPI
SpoSPBC3D6.04c
GO:0000278 mitotic cell cycle P
RCA
SceS000003054
GO:0000279 M phase P
RCA
SceS000003054
GO:0006461 protein complex assembly P
RCA
SceS000003054
GO:0006913 nucleocytoplasmic transport P
IGI
SceS000003054
IPI
SceS000003054
GO:0007094 mitotic cell cycle spindle assembly
checkpoint		 P
IGI
SceS000003054
IMP
SceS000003054
TAS
SpoSPBC3D6.04c
GO:0070683 decatenation checkpoint P
IGI
SceS000003054

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Search for gene by ID or name:

Query species:

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Search for GO info:  

GO info in one table:

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