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Search term: YGL097W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name SRM1
SGD link S000003065
Alternative ID YGL097W
Description Nucleotide exchange factor for Gsp1p, localizes to the nucleus, required for nucleocytoplasmic trafficking of macromolecules; suppressor of the pheromone response pathway; potentially phosphorylated by Cdc28p
Synonyms YGL097W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1426 ACDHYPE

KOGs classification KOGs description
POORLY CHARACTERIZED FOG: RCC1 domain

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g27060 GI:15223423
Arabidopsis thaliana (Ath) At3g02300 GI:15232881
Arabidopsis thaliana (Ath) At3g02510 GI:15232921
Arabidopsis thaliana (Ath) At3g03790 GI:15228636
Arabidopsis thaliana (Ath) At3g15430 GI:18400769
Arabidopsis thaliana (Ath) At3g26100 GI:9279617
Arabidopsis thaliana (Ath) At3g53830 GI:15232347
Arabidopsis thaliana (Ath) At3g55580 GI:15233306
Arabidopsis thaliana (Ath) At5g11580 GI:11290074
Arabidopsis thaliana (Ath) At5g16040 GI:15237253
Arabidopsis thaliana (Ath) At5g48330 GI:15238941
Arabidopsis thaliana (Ath) At5g60870 GI:15239463
Arabidopsis thaliana (Ath) At5g63860 GI:15237540
Caenorhabditis elegans (Cel) CE03024
(WBGene00004304)		 GI:17532079 Q18211
Caenorhabditis elegans (Cel) CE07026 GI:17559318
Caenorhabditis elegans (Cel) CE12118 GI:17508207
Caenorhabditis elegans (Cel) CE19021 GI:17509665
Drosophila melanogaster (Dme) 7295409 GI:18859625
Drosophila melanogaster (Dme) 7295603 GI:7295603
Drosophila melanogaster (Dme) 7296072 GI:7296072
Drosophila melanogaster (Dme) 7296158 GI:7296158 Q9VPU0
Drosophila melanogaster (Dme) 7296478_1 GI:7296478
Drosophila melanogaster (Dme) 7300793 GI:7300793
Drosophila melanogaster (Dme) 7301836 GI:7301836
Homo sapiens (Hsa) Hs13540582
(WBSCR16)		 GI:13540582 Q96I51
Homo sapiens (Hsa) Hs15809006 GI:15809006
Homo sapiens (Hsa) Hs16716337_1 GI:16716337
Homo sapiens (Hsa) Hs17487390 GI:17487390
Homo sapiens (Hsa) Hs19311016_2 GI:19311016
Homo sapiens (Hsa) Hs19923519 GI:19923519
Homo sapiens (Hsa) Hs20483283 GI:20483283
Homo sapiens (Hsa) Hs20486176 GI:20486176
Homo sapiens (Hsa) Hs20554048 GI:20554048
Homo sapiens (Hsa) Hs22049475 GI:22049475
Homo sapiens (Hsa) Hs22056083 GI:22056083
Homo sapiens (Hsa) Hs22056692_2 GI:22056692
Homo sapiens (Hsa) Hs22057585 GI:22057585
Homo sapiens (Hsa) Hs22057603_2 GI:22057603
Homo sapiens (Hsa) Hs22069295 GI:22069295
Homo sapiens (Hsa) Hs22069570 GI:22069570
Homo sapiens (Hsa) Hs4502801 GI:4502801 P18754
Homo sapiens (Hsa) Hs4506581_1 GI:4506581 Q92834
Homo sapiens (Hsa) Hs4557026 GI:4557026
Homo sapiens (Hsa) Hs4557445
(RCBTB2)		 GI:4557445 O95199
Homo sapiens (Hsa) Hs4758520 GI:4758520
Homo sapiens (Hsa) Hs6912330
(SERGEF)		 GI:6912330 Q9UGK8
Saccharomyces cerevisiae (Sce) YAL020c
(S000000018)		 GI:6319299 P31386
Saccharomyces cerevisiae (Sce) YGL097w
(S000003065)		 GI:6321341 P21827
Saccharomyces cerevisiae (Sce) YLR077w
(S000004067)		 GI:6323106 Q08023
Schizosaccharomyces pombe (Spo) SPAC10F6.04 GI:19114167 O42645
Schizosaccharomyces pombe (Spo) SPBC557.03c GI:19112818 P28745
Encephalitozoon cuniculi (Ecu) ECU04g1500 GI:19074229 Q8SS12


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000790 nuclear chromatin C
IDA
SceS000003065
NAS
SpoSPBC557.03c
GO:0005575 cellular_component C
ND
AthAt3g15430
At5g11580
At3g02300
At1g27060
At5g16040
At3g53830
At3g55580
At3g02510
HsaWBSCR16
GO:0005634 nucleus C
IDA
AthAt5g63860
HsaSERGEF
SceS000003065
SpoSPAC10F6.04
SPBC557.03c
GO:0005737 cytoplasm C
IDA
HsaSERGEF
SceS000000018
IPI
SceS000000018
ISS
SpoSPAC10F6.04
GO:0005739 mitochondrion C
IDA
SceS000004067
GO:0005829 cytosol C
IDA
AthAt5g63860
SpoSPAC10F6.04
GO:0003674 molecular_function F
ND
SceS000000018
S000004067
SpoSPAC10F6.04
GO:0003682 chromatin binding F
IDA
AthAt5g63860
ISS
AthAt3g02510
At3g53830
At5g11580
At5g16040
GO:0004871 signal transducer activity F
IMP
SceS000003065
GO:0005085 guanyl-nucleotide exchange factor
activity		 F
ISS
AthAt5g63860
GO:0005087 Ran guanyl-nucleotide exchange factor
activity		 F
IGI
SpoSPBC557.03c
TAS
HsaSERGEF
RCBTB2
GO:0005488 binding F
ISS
AthAt3g03790
At5g48330
At3g55580
GO:0005515 protein binding F
IPI
HsaSERGEF
GO:0008536 Ran GTPase binding F
ISS
AthAt3g02510
At5g16040
At3g02300
At1g27060
At5g11580
At5g60870
At3g15430
At3g53830
At3g26100
GO:0000003 reproduction P
IMP
CelWBGene00004304
GO:0000054 ribosomal subunit export from nucleus P
IMP
SceS000003065
GO:0000226 microtubule cytoskeleton organization P
IGI
SceS000000018
IMP
SceS000000018
GO:0000910 cytokinesis P
IMP
CelWBGene00004304
GO:0002098 tRNA wobble uridine modification P
IMP
SceS000000018
GO:0002119 nematode larval development P
IMP
CelWBGene00004304
GO:0006400 tRNA modification P
ISS
SpoSPAC10F6.04
GO:0006406 mRNA export from nucleus P
IMP
SpoSPBC557.03c
GO:0006407 rRNA export from nucleus P
IMP
SceS000003065
ISS
SpoSPBC557.03c
GO:0006414 translational elongation P
RCA
SceS000000018
GO:0007017 microtubule-based process P
IGI
SceS000000018
ISS
SceS000000018
SpoSPAC10F6.04
GO:0007052 mitotic spindle organization P
IMP
CelWBGene00004304
GO:0007093 mitotic cell cycle checkpoint P
IMP
SpoSPBC557.03c
GO:0007117 budding cell bud growth P
IGI
SceS000000018
IMP
SceS000000018
GO:0007165 signal transduction P
TAS
HsaSERGEF
GO:0007264 small GTPase mediated signal transduction P
IC
SpoSPBC557.03c
GO:0007346 regulation of mitotic cell cycle P
IMP
SpoSPBC557.03c
GO:0008150 biological_process P
ND
AthAt5g48330
At1g27060
At3g03790
At5g60870
At3g15430
At3g02510
At5g16040
At3g26100
At5g11580
At3g53830
At3g55580
At3g02300
HsaWBSCR16
SceS000004067
GO:0009411 response to UV P
IMP
AthAt5g63860
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00004304
GO:0010224 response to UV-B P
IEP
AthAt5g63860
IGI
AthAt5g63860
GO:0016246 RNA interference P
IMP
CelWBGene00004304
GO:0030071 regulation of mitotic metaphase/anaphase
transition		 P
IMP
SpoSPBC557.03c
GO:0031291 Ran protein signal transduction P
IGI
SpoSPBC557.03c
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00004304
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00004304
GO:0050709 negative regulation of protein
secretion		 P
IDA
HsaSERGEF
GO:0051301 cell division P
IMP
CelWBGene00004304
GO:0060623 regulation of chromosome condensation P
IGI
SpoSPBC557.03c
GO:0090307 spindle assembly involved in mitosis P
TAS
SpoSPBC557.03c

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
55567

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) SNHG3-RCC1 GI:114796648
Pan troglodytes (Ptr) SNHG3-RCC1 GI:114555091
Canis familiaris (Cfa) SNHG3-RCC1 GI:73950505
Mus musculus (Mmu) Rcc1
(MGI:1913989)		 GI:19527092 Q3U6D2
Drosophila melanogaster (Dme) Bj1
(FBgn0002638)		 GI:24658888
Anopheles gambiae (Aga) AgaP_AGAP003742 GI:158288412
Caenorhabditis elegans (Cel) ran-3
(CE03024;
WBGene00004304)		 GI:17532079 Q18211
Schizosaccharomyces pombe (Spo) dcd1 GI:19112818
Saccharomyces cerevisiae (Sce) SRM1
(S000003065)		 GI:6321341 P21827
Kluyveromyces lactis (Kla) KLLA0F06600g GI:50310715
Eremothecium gossypii (Ego) AGOS_AFL045C GI:45198474
Magnaporthe grisea (Mgr) MGG_00408 GI:39974891
Neurospora crassa (Ncr) NCU05513.1 GI:32409775


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000790 nuclear chromatin C
IDA
SceS000003065
GO:0005575 cellular_component C
ND
MmuMGI:1913989
GO:0005634 nucleus C
IDA
DmeFBgn0002638
SceS000003065
ISS
DmeFBgn0002638
NAS
DmeFBgn0002638
GO:0005737 cytoplasm C
NAS
DmeFBgn0002638
GO:0003682 chromatin binding F
IDA
DmeFBgn0002638
ISS
DmeFBgn0002638
GO:0004871 signal transducer activity F
IMP
SceS000003065
GO:0005087 Ran guanyl-nucleotide exchange factor
activity		 F
IDA
MmuMGI:1913989
NAS
DmeFBgn0002638
GO:0000003 reproduction P
IMP
CelWBGene00004304
GO:0000054 ribosomal subunit export from nucleus P
IMP
SceS000003065
GO:0000910 cytokinesis P
IMP
CelWBGene00004304
GO:0002119 nematode larval development P
IMP
CelWBGene00004304
GO:0006407 rRNA export from nucleus P
IMP
SceS000003065
GO:0007052 mitotic spindle organization P
IMP
CelWBGene00004304
GO:0007076 mitotic chromosome condensation P
NAS
DmeFBgn0002638
GO:0007346 regulation of mitotic cell cycle P
IDA
DmeFBgn0002638
GO:0007417 central nervous system development P
IDA
DmeFBgn0002638
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00004304
GO:0016246 RNA interference P
IMP
CelWBGene00004304
GO:0030261 chromosome condensation P
ISS
DmeFBgn0002638
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00004304
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00004304
GO:0046822 regulation of nucleocytoplasmic
transport		 P
IMP
DmeFBgn0002638
GO:0050767 regulation of neurogenesis P
IMP
DmeFBgn0002638
GO:0050790 regulation of catalytic activity P
IDA
MmuMGI:1913989
GO:0051301 cell division P
IMP
CelWBGene00004304

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2919

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga6217 ENSANGP00000022492
Ashbya gossypii (Ago) ago3148 AFL045C
Caenorhabditis elegans (Cel) cel2754 C26D10.1
(CE03024;
WBGene00004304)
Candida glabrata (Cgl) cgl3222 CAGL0J05346g
Cryptococcus neoformans (Cne) cne1501 180.m00456
Debaryomyces hansenii (Dha) dha206 DEHA0A04653g
Drosophila melanogaster (Dme) dme8163 CG10480-PA
(FBgn0002638)
Drosophila melanogaster (Dme) dme8164 CG10480-PB
(FBgn0002638)
Drosophila melanogaster (Dme) dme8165 CG10480-PC
(FBgn0002638)
Danio rerio (Dre) dre1079 ENSDARP00000038128
Danio rerio (Dre) dre23573 ENSDARP00000043048
Encephalitozoon cuniculi (Ecu) ecu867 19074229
Takifugu rubripes (Fru) fru376 SINFRUP00000153741
Homo sapiens (Hsa) hsa686 ENSP00000345919
Kluyveromyces lactis (Kla) kla4379 KLLA0F06600g
Mus musculus (Mmu) mmu19024 ENSMUSP00000030726
(MGI:1913989)		 Q3U6D2
Neurospora crassa (Ncr) ncr5355 NCU05513.2
Plasmodium falciparum (Pfa) pfa2290 MAL7P1.38
Saccharomyces cerevisiae (Sce) sce2191 YGL097W
(S000003065)
Schizosaccharomyces pombe (Spo) spo1463 SPBC557.03c P28745
Yarrowia lipolytica (Yli) yli442 YALI0A13299g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000790 nuclear chromatin C
IDA
SceS000003065
NAS
SpoSPBC557.03c
GO:0005575 cellular_component C
ND
MmuMGI:1913989
GO:0005634 nucleus C
IDA
DmeFBgn0002638
SceS000003065
SpoSPBC557.03c
ISS
DmeFBgn0002638
PfaMAL7P1.38
NAS
DmeFBgn0002638
GO:0005737 cytoplasm C
NAS
DmeFBgn0002638
GO:0003682 chromatin binding F
IDA
DmeFBgn0002638
ISS
DmeFBgn0002638
PfaMAL7P1.38
GO:0004871 signal transducer activity F
IMP
SceS000003065
GO:0005087 Ran guanyl-nucleotide exchange factor
activity		 F
IDA
MmuMGI:1913989
IGI
SpoSPBC557.03c
NAS
DmeFBgn0002638
GO:0000003 reproduction P
IMP
CelWBGene00004304
GO:0000054 ribosomal subunit export from nucleus P
IMP
SceS000003065
GO:0000910 cytokinesis P
IMP
CelWBGene00004304
GO:0002119 nematode larval development P
IMP
CelWBGene00004304
GO:0006406 mRNA export from nucleus P
IMP
SpoSPBC557.03c
GO:0006407 rRNA export from nucleus P
IMP
SceS000003065
ISS
SpoSPBC557.03c
GO:0007049 cell cycle P
ISS
PfaMAL7P1.38
GO:0007052 mitotic spindle organization P
IMP
CelWBGene00004304
GO:0007076 mitotic chromosome condensation P
NAS
DmeFBgn0002638
GO:0007093 mitotic cell cycle checkpoint P
IMP
SpoSPBC557.03c
GO:0007264 small GTPase mediated signal transduction P
IC
SpoSPBC557.03c
GO:0007346 regulation of mitotic cell cycle P
IDA
DmeFBgn0002638
IMP
SpoSPBC557.03c
GO:0007417 central nervous system development P
IDA
DmeFBgn0002638
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00004304
GO:0016246 RNA interference P
IMP
CelWBGene00004304
GO:0030071 regulation of mitotic metaphase/anaphase
transition		 P
IMP
SpoSPBC557.03c
GO:0030261 chromosome condensation P
ISS
DmeFBgn0002638
PfaMAL7P1.38
GO:0031291 Ran protein signal transduction P
IGI
SpoSPBC557.03c
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00004304
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00004304
GO:0046822 regulation of nucleocytoplasmic
transport		 P
IMP
DmeFBgn0002638
GO:0050767 regulation of neurogenesis P
IMP
DmeFBgn0002638
GO:0050790 regulation of catalytic activity P
IDA
MmuMGI:1913989
GO:0051301 cell division P
IMP
CelWBGene00004304
GO:0060623 regulation of chromosome condensation P
IGI
SpoSPBC557.03c
GO:0090307 spindle assembly involved in mitosis P
TAS
SpoSPBC557.03c

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC557.03c
(P28745)		 YGL097W
(S000003065)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000790 nuclear chromatin C
IDA
SceS000003065
NAS
SpoSPBC557.03c
GO:0005634 nucleus C
IDA
SceS000003065
SpoSPBC557.03c
GO:0004871 signal transducer activity F
IMP
SceS000003065
GO:0005087 Ran guanyl-nucleotide exchange factor
activity		 F
IGI
SpoSPBC557.03c
GO:0000054 ribosomal subunit export from nucleus P
IMP
SceS000003065
GO:0006406 mRNA export from nucleus P
IMP
SpoSPBC557.03c
GO:0006407 rRNA export from nucleus P
IMP
SceS000003065
ISS
SpoSPBC557.03c
GO:0007093 mitotic cell cycle checkpoint P
IMP
SpoSPBC557.03c
GO:0007264 small GTPase mediated signal transduction P
IC
SpoSPBC557.03c
GO:0007346 regulation of mitotic cell cycle P
IMP
SpoSPBC557.03c
GO:0030071 regulation of mitotic metaphase/anaphase
transition		 P
IMP
SpoSPBC557.03c
GO:0031291 Ran protein signal transduction P
IGI
SpoSPBC557.03c
GO:0060623 regulation of chromosome condensation P
IGI
SpoSPBC557.03c
GO:0090307 spindle assembly involved in mitosis P
TAS
SpoSPBC557.03c

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