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Search term: YGL127C


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name SOH1
SGD link S000003095
Alternative ID YGL127C
Description Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; involved in telomere maintenance; conserved with other metazoan MED31 subunits
Synonyms YGL127C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG4086 ACDHYPE

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSINGINFORMATION STORAGE AND PROCESSING Transcriptional regulator SOH1

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At5g19910 GI:15241215
Caenorhabditis elegans (Cel) CE09877
(WBGene00007026)
GI:17507087 P91869
Drosophila melanogaster (Dme) 7296835 GI:7296835
Homo sapiens (Hsa) Hs7705592
(MED31)
GI:7705592 Q9Y3C7
Saccharomyces cerevisiae (Sce) YGL127c
(S000003095)
GI:6321311 P38633
Schizosaccharomyces pombe (Spo) SPCP31B10.03c GI:19075359 Q9USH1
Encephalitozoon cuniculi (Ecu) ECU11g0360 GI:19074836 Q8SU76


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000003095
SpoSPCP31B10.03c
GO:0005829 cytosol C
IDA
SpoSPCP31B10.03c
GO:0016592 mediator complex C
IDA
SceS000003095
SpoSPCP31B10.03c
IGI
SpoSPCP31B10.03c
NAS
SpoSPCP31B10.03c
GO:0003674 molecular_function F
ND
SceS000003095
GO:0005515 protein binding F
IPI
HsaMED31
GO:0016455 RNA polymerase II transcription mediator
activity
F
TAS
SpoSPCP31B10.03c
GO:0000003 reproduction P
IMP
CelWBGene00007026
GO:0006281 DNA repair P
IPI
SceS000003095
GO:0006311 meiotic gene conversion P
IMP
SceS000003095
GO:0006366 transcription from RNA polymerase II
promoter
P
IDA
SceS000003095
IGI
SceS000003095
IPI
SpoSPCP31B10.03c
GO:0009792 embryo development ending in birth or egg
hatching
P
IMP
CelWBGene00007026
GO:0032569 gene-specific transcription from RNA polymerase II
promoter
P
IC
SpoSPCP31B10.03c
GO:0045144 meiotic sister chromatid segregation P
IMP
SceS000003095
GO:0045449 regulation of transcription P
TAS
SpoSPCP31B10.03c

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
39023

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) SOH1
(S000003095)
GI:6321311 P38633
Kluyveromyces lactis (Kla) KLLA0C05786g GI:50304999
Eremothecium gossypii (Ego) AGOS_AAR164C GI:45184989


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000003095
GO:0016592 mediator complex C
IDA
SceS000003095
GO:0003674 molecular_function F
ND
SceS000003095
GO:0006281 DNA repair P
IPI
SceS000003095
GO:0006311 meiotic gene conversion P
IMP
SceS000003095
GO:0006366 transcription from RNA polymerase II
promoter
P
IDA
SceS000003095
IGI
SceS000003095
GO:0045144 meiotic sister chromatid segregation P
IMP
SceS000003095

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2269

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Anopheles gambiae (Aga) aga4404 ENSANGP00000021911
Ashbya gossypii (Ago) ago352 AAR164C
Arabidopsis thaliana (Ath) ath24266 At5g19910.1
Caenorhabditis elegans (Cel) cel7942 F32H2.2
(CE09877;
WBGene00007026)
Candida glabrata (Cgl) cgl2537 CAGL0I00308g
Cryptococcus neoformans (Cne) cne2865 183.m01870
Dictyostelium discoideum (Ddi) ddi9213 DDB0186404
Debaryomyces hansenii (Dha) dha1880 DEHA0C10175g
Drosophila melanogaster (Dme) dme10899 CG1057-PA
(FBgn0037262)
Drosophila melanogaster (Dme) dme10900 CG1057-PB
(FBgn0037262)
Danio rerio (Dre) dre30696 ENSDARP00000015703
(med31)
Q6DH26
Encephalitozoon cuniculi (Ecu) ecu924 19074836
Takifugu rubripes (Fru) fru693 SINFRUP00000141269
Gallus gallus (Gga) gga9134 ENSGALP00000009649
(MED31)
Homo sapiens (Hsa) hsa12916 ENSP00000225728
(MED31)
Q9Y3C7
Kluyveromyces lactis (Kla) kla1456 KLLA0C05786g
Mus musculus (Mmu) mmu4141 ENSMUSP00000021157
(MGI:1914529)
Q9CXU1
Neurospora crassa (Ncr) ncr553 NCU00569.2
Oryza sativa (Osa) osa48069 5800.m00158
Oryza sativa (Osa) osa56469 6191.m00127
Oryza sativa (Osa) osa274 750.m00150
Plasmodium falciparum (Pfa) pfa1581 PF14_0718
Rattus norvegicus (Rno) rno5462 ENSRNOP00000019919
(RGD:1309457)
Saccharomyces cerevisiae (Sce) sce2222 YGL127C
(S000003095)
Schizosaccharomyces pombe (Spo) spo2898 SPCP31B10.03c Q9USH1
Yarrowia lipolytica (Yli) yli2695 YALI0C24167g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000003095
SpoSPCP31B10.03c
ISO
MmuMGI:1914529
GO:0005829 cytosol C
IDA
SpoSPCP31B10.03c
GO:0016592 mediator complex C
IDA
DmeFBgn0037262
SceS000003095
SpoSPCP31B10.03c
IGI
SpoSPCP31B10.03c
ISS
DmeFBgn0037262
NAS
SpoSPCP31B10.03c
GO:0003674 molecular_function F
ND
SceS000003095
GO:0003702 RNA polymerase II transcription factor
activity
F
IDA
DmeFBgn0037262
GO:0003713 transcription coactivator activity F
IDA
DmeFBgn0037262
GO:0005515 protein binding F
IPI
MmuMGI:1914529
GO:0016455 RNA polymerase II transcription mediator
activity
F
ISS
DmeFBgn0037262
TAS
SpoSPCP31B10.03c
GO:0032403 protein complex binding F
ISO
MmuMGI:1914529
GO:0000003 reproduction P
IMP
CelWBGene00007026
GO:0006281 DNA repair P
IPI
SceS000003095
GO:0006311 meiotic gene conversion P
IMP
SceS000003095
GO:0006357 regulation of transcription from RNA polymerase II
promoter
P
IDA
DmeFBgn0037262
GO:0006366 transcription from RNA polymerase II
promoter
P
IDA
SceS000003095
IGI
SceS000003095
IPI
SpoSPCP31B10.03c
GO:0006367 transcription initiation from RNA polymerase II
promoter
P
IDA
DmeFBgn0037262
ISS
DmeFBgn0037262
GO:0006461 protein complex assembly P
ISO
MmuMGI:1914529
GO:0008595 anterior/posterior axis specification,
embryo
P
IMP
DmeFBgn0037262
GO:0009792 embryo development ending in birth or egg
hatching
P
IMP
CelWBGene00007026
GO:0032569 gene-specific transcription from RNA polymerase II
promoter
P
IC
SpoSPCP31B10.03c
GO:0045144 meiotic sister chromatid segregation P
IMP
SceS000003095
GO:0045449 regulation of transcription P
TAS
SpoSPCP31B10.03c

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPCP31B10.03c
(Q9USH1)
YGL127C
(S000003095)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000003095
SpoSPCP31B10.03c
GO:0005829 cytosol C
IDA
SpoSPCP31B10.03c
GO:0016592 mediator complex C
IDA
SceS000003095
SpoSPCP31B10.03c
IGI
SpoSPCP31B10.03c
NAS
SpoSPCP31B10.03c
GO:0003674 molecular_function F
ND
SceS000003095
GO:0016455 RNA polymerase II transcription mediator
activity
F
TAS
SpoSPCP31B10.03c
GO:0006281 DNA repair P
IPI
SceS000003095
GO:0006311 meiotic gene conversion P
IMP
SceS000003095
GO:0006366 transcription from RNA polymerase II
promoter
P
IDA
SceS000003095
IGI
SceS000003095
IPI
SpoSPCP31B10.03c
GO:0032569 gene-specific transcription from RNA polymerase II
promoter
P
IC
SpoSPCP31B10.03c
GO:0045144 meiotic sister chromatid segregation P
IMP
SceS000003095
GO:0045449 regulation of transcription P
TAS
SpoSPCP31B10.03c

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GO info in one table:

s.khadayate@ucl.ac.uk