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Search term: YGL141W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name HUL5
SGD link S000003109
Alternative ID YGL141W
Description Ubiquitin-conjugating enzyme (E4), elongates polyubiquitin chains on substrate proteins; works in opposition to Ubp6p polyubiquitin-shortening activity; required for retrograde transport of misfolded proteins into cytoplasm during ERAD
Synonyms YGL141W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0942 ACDHYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING E3 ubiquitin protein ligase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At3g17205 GI:15230032
Caenorhabditis elegans (Cel) CE15744
(WBGene00008429)		 GI:17532705 O17736
Drosophila melanogaster (Dme) 7291760
(FBgn0034989)		 GI:19922892
Homo sapiens (Hsa) Hs7661856 GI:7661856
Saccharomyces cerevisiae (Sce) YGL141w
(S000003109)		 GI:6321297 P53119
Schizosaccharomyces pombe (Spo) SPAC167.07c GI:19114290 Q1K9C4
Arabidopsis thaliana (Ath) At3g17205 GI:15230032
Caenorhabditis elegans (Cel) CE15744
(WBGene00008429)		 GI:17532705 O17736
Drosophila melanogaster (Dme) 7291760
(FBgn0034989)		 GI:19922892
Homo sapiens (Hsa) Hs7661856 GI:7661856
Saccharomyces cerevisiae (Sce) YGL141w
(S000003109)		 GI:6321297 P53119
Schizosaccharomyces pombe (Spo) SPAC167.07c GI:19114290 Q1K9C4


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000151 ubiquitin ligase complex C
ISS
AthAt3g17205
GO:0000502 proteasome complex C
IDA
SceS000003109
GO:0005622 intracellular C
ISS
AthAt3g17205
GO:0005634 nucleus C
IDA
SceS000003109
SpoSPAC167.07c
ISS
SpoSPAC167.07c
GO:0005635 nuclear envelope C
IDA
SpoSPAC167.07c
GO:0005737 cytoplasm C
IDA
SceS000003109
ISS
SpoSPAC167.07c
GO:0005829 cytosol C
IDA
SpoSPAC167.07c
GO:0004842 ubiquitin-protein ligase activity F
ISS
AthAt3g17205
SpoSPAC167.07c
GO:0008270 zinc ion binding F
ISS
SpoSPAC167.07c
GO:0034450 ubiquitin-ubiquitin ligase activity F
IDA
SceS000003109
GO:0000003 reproduction P
IMP
CelWBGene00008429
GO:0000209 protein polyubiquitination P
IDA
SceS000003109
GO:0006464 protein modification process P
ISS
AthAt3g17205
GO:0016567 protein ubiquitination P
ISS
AthAt3g17205
SpoSPAC167.07c
GO:0030433 ER-associated protein catabolic
process		 P
IMP
SceS000003109
GO:0033554 cellular response to stress P
IEP
SpoSPAC167.07c

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
39015

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) HUL5
(S000003109)		 GI:6321297 P53119
Kluyveromyces lactis (Kla) KLLA0E14740g GI:50309211
Eremothecium gossypii (Ego) AGOS_ADL280W GI:45187593


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000502 proteasome complex C
IDA
SceS000003109
GO:0005634 nucleus C
IDA
SceS000003109
GO:0005737 cytoplasm C
IDA
SceS000003109
GO:0034450 ubiquitin-ubiquitin ligase activity F
IDA
SceS000003109
GO:0000209 protein polyubiquitination P
IDA
SceS000003109
GO:0030433 ER-associated protein catabolic
process		 P
IMP
SceS000003109

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_901

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga8576 ENSANGP00000004863
Anopheles gambiae (Aga) aga1339 ENSANGP00000013485
Anopheles gambiae (Aga) aga1340 ENSANGP00000027467
Ashbya gossypii (Ago) ago1461 ADL280W
Arabidopsis thaliana (Ath) ath13970 At3g17205.1
Arabidopsis thaliana (Ath) ath16649 At3g53090.1
Caenorhabditis elegans (Cel) cel5122 D2085.4
(CE15744;
WBGene00008429)
Caenorhabditis elegans (Cel) cel18457 Y39A1C.2
(CE19147;
WBGene00003898)
Candida glabrata (Cgl) cgl1566 CAGL0F07821g
Cryptococcus neoformans (Cne) cne3914 185.m02500
Debaryomyces hansenii (Dha) dha6731 DEHA0G23122g
Drosophila melanogaster (Dme) dme6974 CG3356-PA
(FBgn0034989)
Drosophila melanogaster (Dme) dme8681 CG5087-PA
(FBgn0035953)
Danio rerio (Dre) dre18989 ENSDARP00000010405
Danio rerio (Dre) dre21749 ENSDARP00000013222
Takifugu rubripes (Fru) fru29232 SINFRUP00000137557
Takifugu rubripes (Fru) fru10160 SINFRUP00000173025
Gallus gallus (Gga) gga26833 ENSGALP00000001807
Gallus gallus (Gga) gga9432 ENSGALP00000010422
(UBE3C)
Gallus gallus (Gga) gga26837 ENSGALP00000022432
(UBE3B)		 Q98SE8
Homo sapiens (Hsa) hsa8154 ENSP00000280774
(UBE3B)		 Q7Z3V4-2
Homo sapiens (Hsa) hsa29770 ENSP00000309198
(UBE3C)		 Q15386-1
Homo sapiens (Hsa) hsa8152 ENSP00000340596
(UBE3B)		 Q7Z3V4-1
Kluyveromyces lactis (Kla) kla3611 KLLA0E14740g
Mus musculus (Mmu) mmu19833 ENSMUSP00000045998
(MGI:2140998)		 Q80U95
Mus musculus (Mmu) mmu20726 ENSMUSP00000072294
Mus musculus (Mmu) mmu20725 ENSMUSP00000073652
(MGI:1891295)		 Q9ES34
Neurospora crassa (Ncr) ncr4661 NCU04800.2
Oryza sativa (Osa) osa17910 3324.m00129
Oryza sativa (Osa) osa32857 4495.m00157
Oryza sativa (Osa) osa395 753.m00306
Plasmodium falciparum (Pfa) pfa652 PF11_0201
Rattus norvegicus (Rno) rno20562 ENSRNOP00000015232
(RGD:1559986)
Saccharomyces cerevisiae (Sce) sce2236 YGL141W
(S000003109)
Schizosaccharomyces pombe (Spo) spo4113 SPAC167.07c Q1K9C4
Yarrowia lipolytica (Yli) yli699 YALI0A20372g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000151 ubiquitin ligase complex C
ISS
AthAt3g17205
At3g53090
GO:0000502 proteasome complex C
IDA
SceS000003109
GO:0005622 intracellular C
ISS
AthAt3g17205
At3g53090
GO:0005634 nucleus C
IDA
SceS000003109
SpoSPAC167.07c
ISS
SpoSPAC167.07c
GO:0005635 nuclear envelope C
IDA
SpoSPAC167.07c
GO:0005737 cytoplasm C
IDA
SceS000003109
ISS
SpoSPAC167.07c
GO:0005829 cytosol C
IDA
SpoSPAC167.07c
GO:0004842 ubiquitin-protein ligase activity F
ISS
AthAt3g17205
At3g53090
DmeFBgn0035953
SpoSPAC167.07c
GO:0008270 zinc ion binding F
ISS
SpoSPAC167.07c
GO:0034450 ubiquitin-ubiquitin ligase activity F
IDA
SceS000003109
GO:0000003 reproduction P
IMP
CelWBGene00008429
GO:0000209 protein polyubiquitination P
IDA
SceS000003109
GO:0006464 protein modification process P
ISS
AthAt3g17205
At3g53090
GO:0016567 protein ubiquitination P
ISS
AthAt3g17205
At3g53090
SpoSPAC167.07c
GO:0030433 ER-associated protein catabolic
process		 P
IMP
SceS000003109
GO:0033554 cellular response to stress P
IEP
SpoSPAC167.07c

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC167.07c
(Q1K9C4)		 YGL141W
(S000003109)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000502 proteasome complex C
IDA
SceS000003109
GO:0005634 nucleus C
IDA
SceS000003109
SpoSPAC167.07c
ISS
SpoSPAC167.07c
GO:0005635 nuclear envelope C
IDA
SpoSPAC167.07c
GO:0005737 cytoplasm C
IDA
SceS000003109
ISS
SpoSPAC167.07c
GO:0005829 cytosol C
IDA
SpoSPAC167.07c
GO:0004842 ubiquitin-protein ligase activity F
ISS
SpoSPAC167.07c
GO:0008270 zinc ion binding F
ISS
SpoSPAC167.07c
GO:0034450 ubiquitin-ubiquitin ligase activity F
IDA
SceS000003109
GO:0000209 protein polyubiquitination P
IDA
SceS000003109
GO:0016567 protein ubiquitination P
ISS
SpoSPAC167.07c
GO:0030433 ER-associated protein catabolic
process		 P
IMP
SceS000003109
GO:0033554 cellular response to stress P
IEP
SpoSPAC167.07c

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GO info in one table:

s.khadayate@ucl.ac.uk